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SPIRES-BOOKS: FIND KEYWORD ALLERGY *END*INIT* use /tmp/qspiwww.webspi1/18606.38 QRY 131.225.70.96 . find keyword allergy ( in books using www Cover
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Call number:SPRINGER-2008-9780387728353:ONLINE Show nearby items on shelf
Title:The Frailty Model [electronic resource]
Author(s): Luc Duchateau
Paul Janssen
Date:2008
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Clustered survival data are encountered in many scientific disciplines including human and veterinary medicine, biology, epidemiology, public health and demography. Frailty models provide a powerful tool to analyse clusteredsurvival data. In contrast to the large number of research publications on frailty models, relatively few statistical software packages contain frailty models. It is demanding for statistical practitioners and graduate students tograsp a good knowledge on frailty models from the e xisting literature. This book provides an in-depth discussion and explanation of the basics of frailty model methodology for such readers. The discussion includes parametric andsemiparametric frailty models and accelerated failure time models. Common tech niques to fit frailty models include the EM-algorithm, penalised likelihood techniques, Laplacian integration and Bayesian techniques. More advanced frailtymodels for hierarchical data are also included. Real-life examples are used to demonstrate how part icular frailty models can be fitted and how the results should be interpreted. The programs to fit all the worked-out examples in thebook are available from the Springer website with most of the programs developed in the freeware packages R and Winbugs. T he book starts with a brief overview of some basic concepts in classical survival analysis, collecting what isneeded for the reading on the more complex frailty models. Luc Duchateau is Associate Professor of Statistics at the Faculty of Veterinary Medici ne of the Ghent University, Belgium. He is board member of the Quetelet Society (BelgianRegion of the International Biometric Society) and of the International Biometric Society Channel Network. He has collaborated extensively with physicians in oncology and allergy, public health workers and veterinarians, and is anauthor of numerous papers in statistical, medical and veterinarian journals. Paul Janssen is Professor of Statistics at the Centre for Stat
Note:Springer eBooks
Contents:Parametric proportional hazards models with gamma frailty
Alternatives for the frailty model
Frailty distributions
The semiparametric frailty model
Multifrailty and multilevel models
Extensions of the frailty model
ISBN:9780387728353
Series:e-books
Series:SpringerLink (Online service)
Series:Mathematics and Statistics (Springer-11649)
Keywords: Statistics , Oncology , Emerging infectious diseases , Epidemiology , Computer simulation , Biometrics
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Call number:SPRINGER-1988-9783642731518:ONLINE Show nearby items on shelf
Title:Photosensitisation Molecular, Cellular and Medical Aspects
Author(s):
Date:1988
Size:1 online resource (521 p.)
Note:10.1007/978-3-642-73151-8
Contents:Past, present and future of photosensitisers -- Primary photochemical processes -- Continuous irradiation and emission methods -- Fluorescence lifetimes of chromophores interacting with biomolecules -- Pulse radiolysis -- The
photophysics and photochemistry of some dye sensitisers -- Spectral properties of hypericin-metal complexes -- Photolysis of the photosensitisers biothionol and fentichlor -- Laser flash photolysis and singlet oxygen quantum yields of
anthracyclines -- Characterization of the anthralin radical by pulse radiolysis and laser photolysis -- Photophysical and photodynamic properties of new photosensitisers -- Photoacoustic spectroscopy in biomedical sciences -- Absolute
determination of quantum yields of Photosensitisation by time resolved thermal lensing -- Hematoporphyrin-manganese: a contrast agent for tumors in magnetic resonance imaging -- Interactions of light with biological tissue -- Optical
measurements on tissue layers -- The optical properties of tissues at 633 nanometers as related to light dosimetry in photodynamic therapy -- Applications of the change in tissue optical properties caused by the prescence of
photosensitisers -- Mechanistic characterization of photosensitised reactions -- Singlet oxygen involvement in membrane photomodification -- Standards for singlet oxygen sensitization -- Biological and chemical photoproduction of
hydrogen peroxide -- Cell models -- Biological target molecules and cell structures in mammalian cell photosensitization -- Porphyrin photosensitisation of mitochondria -- Nuclear damage in mammalian cell photosensitization --
Biological implications of lesions introduced into DNA by singlet oxygen -- Damage to DNA repair in Murine L929 fibroblasts induced by the photodynamic action of HPD -- Photoinactivation of cells studied by 31P-NMR -- Sunlight,
melanogenesis, and free radicals in the skin -- Pulsed irradiation studies of some reactions of melanin precursors -- Melanin and photoprotection -- Pigmentogenic effects of psoralens -- Melanogenesis and light regulated experimental
carcinogenesis -- Role of melanins and drugs in cutaneous photosensitivity -- Skin and related photoreactions -- Phototherapy for pruritus in primary biliary cirrhosis -- Psoralens: a review -- Mutagenesis of psoralens on eukaryotic
cells -- Bichromophoric systems to study the base-psoralen photoreactions -- Photophysical behaviour of 5-methoxypsoralen in different solvent systems -- Furocoumarin photosensitized reations with fatty acids -- Furocoumarin
photosensitisation: wavelength dependence of monoadduct and crosslink formation in yeast -- The use of animal models for human risk assessment of psoralen photocarcinogenesis -- Phototherapy and PUVA therapy -- Ocular phototoxicity --
Ocular protection for patients undergoing PUVA or photodynamic therapy -- Diseases associated with defective tetrapyrrole metabolism: porphyria and hyperbilirubinemia -- Photophysical and related aspects of haematoporphyrin and related
systems -- Photophysical properties of chlorin derivatives of haematoporphyrin -- Insoluble polymer-supported porphyrins as photosensitisers -- Water-soluble metal napthalocyanines as potential photosensitisers -- HPDs chemical and
biophysical studies -- Studies of Photofrin II - induced photosensitisation of human red blood cells: variability between blood samples -- In vitro uptake and photodynamic action of tetra (3-hydroxyphenyl) porphyrin in cells --
Quantitative aspects of the interaction of porphyrins with cells -- Uptake of the anticancer porphyrin mixture Photofrin II by human fibroblasts from low density lipoprotein, high density lipoprotein and albumin -- Parameters
influencing photodynamic selectivity of normal progenitors vs leukemia cells -- Porphyrin-protein interaction -- Photomodification of porphyrins in biological systems -- Photoradiation therapy of rodent tumors -- Targets of porphyrins
photodynamic action in vivo -- Phthalocyanines as sensitisers for photodynamic therapy of cancer -- Pulsed laser studies of aluminium phthalocyanine derivatives -- Zn-phthalocyanine as a possible phototherapeutic agent for tumors --
Photochemotherapy - clinical aspects -- In vivo fluorescence from mouse skin: spectral evidence for the presence of chlorophyll derivatives -- DHE uptake and PDT response in an in vitro tumor model -- Fluorescence diagnosis and
photodynamic therapy evaluation of sensitisers by comparison of their pharmacokinetics -- In vivo aspects of PDT -- Alternative synthesis of “DHE” analogues -- New photosensitisers for PDT -- A dose response study of two purpurins on
the AY-27 rat bladder tumor -- In vivo cytotoxicity of metallopurpurins to bladder tumors -- Potential phototoxicity in the photosensitive patient -- Participants
ISBN:9783642731518
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:NATO ASI Series, Series H: Cell Biology : 15
Keywords: Physics , Immunology , Neurosciences , Allergy , Biochemistry , Cell biology , Biophysics , Biological physics , Physics , Biophysics and Biological Physics , Cell Biology , Biochemistry, general , Neurosciences , Allergology , Immunology
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Call number:SPRINGER-1976-9781461343042:ONLINE Show nearby items on shelf
Title:Molecular and Biological Aspects of the Acute Allergic Reaction
Author(s):
Date:1976
Size:1 online resource (464 p.)
Note:10.1007/978-1-4613-4304-2
Contents:Session I Structure of Allergens and Regulation of IgE Immune Response -- Common Characteristics of Major Allergens -- Allergy: A Model for Studying the Genetics of Human Immune Response -- Induction and Suppression of IgE Antibody
Response -- T Cell-Mediated Regulation of IgE Antibody Production -- Session II IgE In Rats: An Experimental Model -- Production of IgE and Reaginic Antibody in Rats in Relation to Worm Infections -- IgE-Myelomas in Rats -- Macrophage
Cytotoxicity Mediated by IgE Antibody -- Session III IgE-Dependent Activation and Release of Chemical Mediators -- Function and Structure of Immunoglobulin E (IgE) -- Functions and Development of Cell Receptors for IgE -- Modes of
Action of Antigen-Antibody Reaction and Compound 48/80 in Histamine Release -- Discussion Remark: Protein Kinases in Rat Mast Cells -- The Interdependence of Allergic and Inflammatory Processes -- Influence of Calcium Ions and
Metabolic Energy (ATP) on Histamine Release -- Molecular Events in Membrane Fusion Occurring During Mast Cell Degranulation -- Mast Cell-Derived Mediators: Structural and Functional Diversity and Regulation of Expression --
Prostaglandins and Related Substances in Acute Allergie Reactions -- Session IV Generation of Biologically Active Substances and Mediator - Target Cell Interactions -- The Anaphylatoxins: Formation, Structure, Function and Control --
Some Interrelations Among Chemotaxis, Lysosomal Enzyme Secretion and Phagocytosis by Neutrophils -- The Hageman Factor System: Mechanism of Contact Activation -- Neutrophil Generation of Permeability Enhancing Peptides from Plasma
Substrates -- Specificity and Modulation of the Eosinophil Polymorphonuclear Leukocyte Response to the Eosinophil Chemotactic Factor of Anaphylaxis (ECF-A) -- Lymphocyte Mediators, Activated Macrophages, and Tumor Immunity --
Participants
ISBN:9781461343042
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Medicine , Immunology , Biomedicine , Immunology
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