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SPIRES-BOOKS: FIND KEYWORD CANCER RESEARCH *END*INIT* use /tmp/qspiwww.webspi1/18373.151 QRY 131.225.70.96 . find keyword cancer research ( in books using www Cover
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Call number:9783319430300:ONLINE Show nearby items on shelf
Title:Nanoscale Insights into Ion-Beam Cancer Therapy
Author(s):
Date:2017
Size:1 online resource (XX, 498 p. 183 illus., 159 illus. in color p.)
Contents:Multiscale Physics of Ion-Beam Cancer Therapy -- Theory of atomic and molecular collisions, quantum and classical molecular dynamics (theory) -- Fundamental collisions (experiment, both electrons and ions, stress on biomolecules) --
Dissociative electron attachment process -- Ions propagation through biological medium -- Irradiation of biological targets with ions -- Monte Carlo track structure simulations -- Radiation nanochemistry -- Radiobiological effects --
Advanced therapies based on nanoprocesses and technologies: radiobiological effects with nanoparticles -- Treatment planning systems -- Medical applications (overview of the heavy ion therapy medical centers and practices)
ISBN:9783319430300
Series:eBooks
Series:Springer eBooks
Series:Springer 2017 package
Keywords: Physics , Cancer research , Nanochemistry , Nuclear physics , Heavy ions , Hadrons , Nanoscale science , Nanoscience , Nanostructures , Medical physics , Radiation , Physics , Medical and Radiation Physics , Cancer Research , Nanoscale Science and Technology , Nuclear Physics, Heavy Ions, Hadrons , Nanochemistry , Biological and Medical Physics, Biophysics
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Call number:SPRINGER-2016-9783319412139:ONLINE Show nearby items on shelf
Title:The Statistical Physics of Fixation and Equilibration in Individual-Based Models
Author(s): Peter Ashcroft
Date:2016
Size:1 online resource (13 p.)
Note:10.1007/978-3-319-41213-9
Contents:Introduction -- Technical Background -- Finite Populations in Switching Environments -- Fixation Time Distribution -- Metastable States in Cancer Initiation -- The WKB Method: A User-guide -- Conclusions
ISBN:9783319412139
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Physics , Cancer research , Bioinformatics , Game theory , Probabilities , Biomathematics , Sociophysics , Econophysics , Physics , Socio- and Econophysics, Population and Evolutionary Models , Mathematical and Computational Biology , Bioinformatics , Probability Theory and Stochastic Processes , Game Theory, Economics, Social and Behav. Sciences , Cancer Research
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Call number:SPRINGER-2016-9783319395371:ONLINE Show nearby items on shelf
Title:Grating-Based X-Ray Phase-Contrast Mammography
Author(s): Kai Hermann Scherer
Date:2016
Size:1 online resource (33 p.)
Note:10.1007/978-3-319-39537-1
Contents:Introduction -- Theoretical Background -- Experimental Setup & Methods Development -- Bi-directional Phase-Contrast Mammography -- Screening Value of Phase-Contrast Mammography -- Microcalcification Assessment with Dark-Field
Mammography -- Toward Clinically Compatible Phase-Contrast Mammography -- Non-invasive Kidney Stone Differentiation Using Dark-Field Radiography -- Summary & Outlook
ISBN:9783319395371
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Physics , Cancer research , Radiology , Medical physics , Radiation , Physics , Medical and Radiation Physics , Diagnostic Radiology , Cancer Research
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Call number:SPRINGER-2016-9783319336428:ONLINE Show nearby items on shelf
Title:Applications of Elliptic Carleman Inequalities to Cauchy and Inverse Problems
Author(s): Mourad Choulli
Date:2016
Size:1 online resource (81 p.)
Note:10.1007/978-3-319-33642-8
Contents:1 Preliminaries -- 2 Uniqueness of continuation and Cauchy problems -- 3 Determining the surface impedance of an obstacle from the scattering amplitude -- 4 Determining a corrosion coecient from a boundary measurement and an attenuation coecient fr om an internal measurement
ISBN:9783319336428
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Mathematics , Cancer research , Partial differential equations , Applied mathematics , Engineering mathematics , Physics , Mathematics , Partial Differential Equations , Mathematical Methods in Physics , Cancer Research , Applications of Mathematics , Appl.Mathematics/Computational Methods of Engineering
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Call number:SPRINGER-2014-9781461488996:ONLINE Show nearby items on shelf
Title:Hadron Therapy Physics and Simulations [electronic resource]
Author(s): Marcos dvila Nunes
Date:2014
Publisher:New York, NY : Springer New York : Imprint: Springer
Size:1 online resource
Note:This brief provides an in-depth overview of the physics of hadron therapy, ranging from the history to the latest contributions to the subject. It covers the mechanisms of protons and carbon ions at the molecular level (DNA breaksand proteins 53BP1 a nd RPA), the physics and mathematics of accelerators (Cyclotron and Synchrotron), microdosimetry measurements (with new results so far achieved), and Monte Carlo simulations in hadron therapy using FLUKA (CERN) andMCHIT (FIAS) software. The text also incl udes information about proton therapy centers and carbon ion centers (PTCOG), as well as a comparison and discussion of both techniques in treatment planning and radiation monitoring. This briefis suitable for newcomers to medical physics as well as seaso ned specialists in radiation oncology
Contents:Brief History of Radiotherapy
Time line of Hadron Therapy
Mechanism of Hadron Therapy at molecular level
Strengthening concepts about variations in therapy by radiation
Which conditions can be treated by Hadron Therapy?
Hospitals and Research Centers for cancer treatment by Hadron
Particle therapy facilities in operation (incl. patient statistics)
Tumors: localization
Using boro
therapy to treat tumors
Which therapy must be used? Where? Conduct before and during treatment used at HIT
After Modern Radiotherapy: estimating risk of second malignancies
Particles a
ISBN:9781461488996
Series:eBooks
Series:SpringerLink
Series:SpringerBriefs in Physics, 2191-5423
Series:Physics and Astronomy (Springer-11651)
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Call number:SPRINGER-2013-9781461455868:ONLINE Show nearby items on shelf
Title:Epidemiologic Studies in Cancer Prevention and Screening [electronic resource]
Author(s): Anthony B Miller
Date:2013
Publisher:New York, NY : Springer New York : Imprint: Springer
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Epidemiologic Studies in Cancer Prevention and Screening is the first comprehensive overview of the evidence base for both cancer prevention and screening. This book is directed to the many professionals in government, academia,public health and heal th care who need up to date information on the potential for reducing the impact of cancer, including physicians, nurses, epidemiologists, and research scientists. The main aim of the book is to provide arealistic appraisal of the evidence for both cancer prevention and cancer screening. In addition, the book provides an accounting of the extent programs based on available knowledge have impacted populations. It does this through: 1.Presentation of a rigorous and realistic evaluation of the evidence for p opulation-based interventions in prevention of and screening for cancer, with particular relevance to those believed to be applicable now, or on the cusp ofapplication 2. Evaluation of the relative contributions of prevention and screening 3. Discussion o f how, within the health systems with which the authors are familiar, prevention and screening for cancer can be enhanced. Overview ofthe evidence base for cancer prevention and screening, as demonstrated in Epidemiologic Studies in Cancer Prevention and Screening, is critically important given current debates within the scientific community. Of the five componentsof cancer control, prevention, early detection (including screening) treatment, rehabilitation and palliative care, prevention is regarded as t he most important. Yet the knowledge available to prevent many cancers is incomplete, andeven if we know the main causal factors for a cancer, we often lack the understanding to put this knowledge into effect. Further, with the long natural history of mos t cancers, it could take many years to make an appreciable impactupon the incidence of the cancer. Because of these facts, many have come to believe that screening has the most potential for reduction o
Note:Springer eBooks
Contents:Health promotion in cancer prevention
Preventing cancer by ending tobacco use
Prevention of occupationally
induced cancer
The prospects for successful HPV vaccination for cervix and other cancers
Prevention of cancers due to infection
Applying physical activity in cancer prevention
Cancer prevention in the United States
The role of nutrition in cancer prevention
Chemoprevention of cancer: from nutritional epidemiology to clinical trials
The role of hormonal factors in cancer prevention
Controlling environmental causes of cancer
A historical moment: cancer preve
ISBN:9781461455868
Series:e-books
Series:SpringerLink (Online service)
Series:Statistics for Biology and Health, 1431-8776 : v79
Series:Mathematics and Statistics (Springer-11649)
Keywords: Statistics
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Call number:SPRINGER-2012-9783642237492:ONLINE Show nearby items on shelf
Title:Photons in Natural and Life Sciences [electronic resource] : An Interdisciplinary Approach
Author(s): Hans-Joachim Lewerenz
Date:2012
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:The book describes first the principle photon generation processes from nuclear reactions, electron motion and from discrete quantum transitions. It then focuses on the use of photons in various selected fields of modern naturaland life sciences. It bridges disciplines such as physics, chemistry, earth- and materials science, proteomics, information technology, photoelectrochemistry, photosynthesis and spintronics. Advanced light sources and their use innatural and life sciences are emphasized and th e effects related to the quantum nature of photons (quantum computing, teleportation) are described. The content encompasses among many other examples the role of photons on the origin oflife and on homochirality in biology, femtosecond laser slicing, pho tothermal cancer therapy, the use of gamma rays in materials science, photoelectrochemical surface conditioning, quantum information aspects and photo-spintronics. Thebook is written for scientists and graduate students from all related disciplines who ar e interested in the science beyond their immediate research field. It is meant to encourage interdisciplinary research and development in an agewhere nanoscience results in a convergence of formerly more disparate science
Note:Springer eBooks
Contents:On the Origin of Light
Sources of Spectral Photon Radiation
Photon Generation in Electronic Transition High
Energy Lasers
Applications in Chemistry, Physics, Materials Science and Biology
Exploiting the Quantum Nature of Photons
Spintronics
ISBN:9783642237492
Series:e-books
Series:SpringerLink (Online service)
Series:Springer Series in Optical Sciences, 0342-4111 : v157
Series:Physics and Astronomy (Springer-11651)
Keywords: Engineering , Nanotechnology
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Call number:SPRINGER-2012-9783642214141:ONLINE Show nearby items on shelf
Title:Ion Beam Therapy [electronic resource] : Fundamentals, Technology, Clinical Applications
Author(s): Ute Linz
Date:2012
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:The book provides a detailed, up-to-date account of the basics, the technology, and the clinical use of ion beams for radiation therapy. Theoretical background, technical components, and patient treatment schemes are delineated bythe leading experts that helped to develop this field from a research niche to its current highly sophisticated and powerful clinical treatment level used to the benefit of cancer patients worldwide. Rather than being a side-by-sidecollection of articles, this book consists of related chapters. It is a common achievement by 76 experts from around the world. Their expertise reflects the diversity of the field with radiation therapy, medical and acceleratorphysics, radiobiology, computer science, engineering, and health econom ics. The book addresses a similarly broad audience ranging from professionals that need to know more about this novel treatment modality or consider to enter thefield of ion beam therapy as a researcher. However, it is also written for the interested publ ic and for patients who might want to learn about this treatment option
Note:Springer eBooks
Contents:Ion Beam Therapy in Perspective
Physical and Biological Aspects
Models and Preclinical Studies
Clinical Results and Indications
Beam Preparation and Control
Patient Positioning and Treatment Planning
Individual Facilities and Management Issues
Future Developments
ISBN:9783642214141
Series:e-books
Series:SpringerLink (Online service)
Series:Biological and Medical Physics, Biomedical Engineering, 1618-7210 : v320
Series:Physics and Astronomy (Springer-11651)
Keywords: Oncology , Nuclear medicine , Radiotherapy , Biomedical engineering
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Call number:SPRINGER-2012-9783642214134:ONLINE Show nearby items on shelf
Title:Ion Beam Therapy [electronic resource]
Author(s): Ute Linz
Date:2012
Publisher:Springer Berlin Heidelberg
Size:1 online resource
Note:Monograph
Note:Springer 2012 Physics and Astronomy eBook collection
Note:Springer e-book platform
ISBN:9783642214134
Series:Biological and Medical Physics, Biomedical Engineering
Series:e-books
Keywords: Medical and Radiation Physics , Radiotherapy , Nuclear Medicine , Biomedical Engineering , Energy, general , Cancer Research
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Call number:SPRINGER-2012-9781461438342:ONLINE Show nearby items on shelf
Title:Geometric Optimal Control [electronic resource] : Theory, Methods and Examples
Author(s): Heinz Schttler
Urszula Ledzewicz
Date:2012
Publisher:New York, NY : Springer New York : Imprint: Springer
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:This book gives a comprehensive treatment of the fundamental necessary and sufficient conditions for optimality for finite-dimensional, deterministic, optimal control problems. The emphasis is on the geometric aspects of thetheory and on illustrating how these methods can be used to solve optimal control problems. It provides tools and techniques that go well beyond standard procedures and can be used to obtain a full understanding of the global structureof solutions for the underlying problem. The t ext includes a large number and variety of fully worked out examples that range from the classical problem of minimum surfaces of revolution to cancer treatment for novel therapyapproaches. All these examples, in one way or the other, illustrate the power of geometric techniques and methods. The versatile text contains material on different levels ranging from the introductory and elementary to the advanced.Parts of the text can be viewed as a comprehensive textbook for both advanced undergraduate and all level graduate courses on optimal control in both mathematics and engineering departments. The text moves smoothly from the moreintroductory topics to those parts that are in a monograph style were advanced topics are presented. While the presentation is mathematically rigorous, it is carried out in a tutorial style that makes the text accessible to a wideaudience of researchers and students from various fields, including the mathematical sciences and engineering. Heinz Schttler is an Associate Professor at Washington University in St. Louis in the Department of Electrical andSystems Engineering, Urszula Ledzewicz is a Distinguished Research Professor at Southern Illinois University Edwardsville in the Department of Mathematics and Statistics
Note:Springer eBooks
Contents:The Calculus of Variations: A Historical Perspective
The Pontryagin Maximum Principle: From Necessary Conditions to the Construction of an Optimal Solution
Reachable Sets of Linear Time
Invariant Systems: From Convex Sets to the Bang
Bang Theorem
The High
Order Maximum Principle: From Approximations of Reachable Sets to High
Order Necessary Conditions for Optimality
The Method of Characteristics: A Geometric Approach to Sufficient Conditions for a Local Minimum
Synthesis of Optimal Controlled Trajectories: FromLocal to Global Solutions
Control
Affine Systems in Low Dimensions
ISBN:9781461438342
Series:e-books
Series:SpringerLink (Online service)
Series:Interdisciplinary Applied Mathematics, 0939-6047 : v38
Series:Mathematics and Statistics (Springer-11649)
Keywords: Mathematics , Differential Equations , Global differential geometry , Mathematical optimization , Engineering mathematics
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Call number:SPRINGER-2012-9781461436157:ONLINE Show nearby items on shelf
Title:Essentials of Stochastic Processes [electronic resource]
Author(s): Richard Durrett
Date:2012
Edition:2nd ed. 2012
Publisher:New York, NY : Springer New York : Imprint: Springer
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:This book is for a first course in stochastic processes taken by undergraduates or masters students who have had a course in probability theory. It covers Markov chains in discrete and continuous time, Poisson processes,renewal processes, martingales , and mathematical finance. One can only learn a subject by seeing it in action, so there are a large number of examples and more than 300 carefully chosen exercises to deepen the readers understanding The book has undergone a thorough revision since the first edition. There are many new examples and problems with solutions that use the TI-83 to eliminate the tedious details of solving linear equations by hand. Some material thatwas too advanced for the level has been eliminated while the treatment of oth er topics useful for applications has been expanded. In addition, the ordering of topics has been improved. For example, the difficult subject ofmartingales is delayed until its usefulness can be seen in the treatment of mathematical finance. Richard Dur rett received his Ph.D. in Operations Research from Stanford in 1976. He taught at the UCLA math department for nine yearsand at Cornell for twenty-five before moving to Duke in 2010. He is the author of 8 books and almost 200 journal articles, and has su pervised more that 40 Ph.D. students. Most of his current research concerns the applications ofprobability to biology: ecology, genetics, and most recently cancer
Note:Springer eBooks
Contents:Markov Chains
Poisson Processes
Renewal Processes
Continuous Time Markov Chains
Martingales
Mathematical Finance
A Review of Probability
ISBN:9781461436157
Series:e-books
Series:SpringerLink (Online service)
Series:Springer Texts in Statistics, 1431-875X
Series:Mathematics and Statistics (Springer-11649)
Keywords: Statistics , Distribution (Probability theory) , Mathematical statistics
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Call number:SPRINGER-2011-9789048132553:ONLINE Show nearby items on shelf
Title:Acoustical Imaging [electronic resource] : Volume 30
Author(s): Michael P Andr
Joie P Jones
Hua Lee
Date:2011
Publisher:Dordrecht : Springer Netherlands
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:The International Symposium on Acoustical Imaging is a unique forum for advanced research, covering new technologies, developments, methods and theories in all areas of acoustics. This interdisciplinary Symposium has been takingplace every two years since 1968. In the course of the years the proceedings volumes in the Acoustical Imaging Series have become a reference for cutting-edge research in the field. In 2009 the 30th International Symposium onAcoustical Imaging was held in Monterey, CA, USA, Ma rch 1-4. Offering both a broad perspective on the state-of-the-art as well as in-depth research contributions by the specialists in the field, this Volume 30 in the Series containsan excellent collection of forty three papers presented in five major categ ories: Biomedical Imaging Acoustic Microscopy Non-Destructive Evaluation Systems Analysis Signal Analysis and Image Processing Audience Researchers in medicalimaging and biomedical instrumentation experts
Note:Springer eBooks
Contents:Preface. Part I BIOMEDICAL IMAGING Performance of a Method to Standardize Breast Ultrasound Interpretation Using Image Processing and Case
Based Reasoning
High Resolution Ultrasonic Method for 3D Fingerprint Recognizable Characteristics In Biometrics Identification
Ultrasonic Detection of Metastases in Dissected Lymph Nodes of Cancer Patients
Measurement of Mechanical Properties of Soft Tissue with Ultrasound Vibrometry
Vector Doppler Method Based on an Automatic Transverse Angle Tracking Procedure
Proposal for Blood
Flow Imaging by Contrast Echo Using Counter
Crossed Beams
I
ISBN:9789048132553
Series:e-books
Series:SpringerLink (Online service)
Series:Acoustical Imaging, 0270-5117 : v30
Series:Physics and Astronomy (Springer-11651)
Keywords: Radiology, Medical , Diagnosis, Ultrasonic , Acoustics
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Call number:SPRINGER-2010-9783642156038:ONLINE Show nearby items on shelf
Title:The Role of Model Integration in Complex Systems Modelling [electronic resource] An Example from Cancer Biology
Author(s): Manish Patel
Sylvia Nagl
Date:2010
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Model integration the process by which different modelling efforts can be brought together to simulate the target system is a core technology in the field of Systems Biology. In the work presented here model integrationwas addressed directly taking cancer systems as an example. An in-depth literature review was carried out to survey the model forms and types currently being utilised. This was used to formalise the main challenges that modelintegration poses, namely that of paradigm (the formalism o n which a model is based), focus (the real-world system the model represents) and scale. A two-tier model integration strategy, including a knowledge-driven approach to addressmodel semantics, was developed to tackle these challenges. In the first step a novel description of models at the level of behaviour, rather than the precise mathematical or computational basis of the model, is developed by distillinga set of abstract classes and properties. These can accurately describe model behaviour and hence de scribe focus in a way that can be integrated with behavioural descriptions of other models. In the second step this behaviour isdecomposed into an agent-based system by translating the models into local interaction rules. The book provides a detailed and highly integrated presentation of the method, encompassing both its novel theoretical and practical aspects,which will enable the reader to practically apply it to their model integration needs in academic research and professional settings. The text is s elf-supporting. It also includes an in-depth current bibliography to relevant researchpapers and literature. The review of the current state of the art in tumour modelling provides added value
Note:Springer eBooks
Contents:Part 1 Introduction
Part 2 Nature to Numbers: Complex Systems Modelling of Cancer
Part 3 Coping with Complexity: Modelling of Complex Systems
Part 4 Complexity and Model Integration: Formalisations
Part 5 Novel Strategies for Integrating Models into Systems
level Simulations
Part 6 Experiments in Model Integration
Part 7 Discussion
ISBN:9783642156038
Series:e-books
Series:SpringerLink (Online service)
Series:Understanding Complex Systems, 1860-0832
Series:Physics and Astronomy (Springer-11651)
Keywords: Engineering , Oncology , Biological models
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Call number:SPRINGER-2010-9781441969446:ONLINE Show nearby items on shelf
Title:Frontiers of Statistical Decision Making and Bayesian Analysis [electronic resource] : In Honor of James O. Berger
Author(s): Ming-Hui Chen
Peter Mller
Dongchu Sun
Keying Ye
Dipak K Dey
Date:2010
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Research in Bayesian analysis and statistical decision theory is rapidly expanding and diversifying, making it increasingly more difficult for any single researcher to stay up to date on all current research frontiers. This bookprovides a review of c urrent research challenges and opportunities. While the book can not exhaustively cover all current research areas, it does include some exemplary discussion of most research frontiers. Topics include objectiveBayesian inference, shrinkage estimation and other decision based estimation, model selection and testing, nonparametric Bayes, the interface of Bayesian and frequentist inference, data mining and machine learning, methods forcategorical and spatio-temporal data analysis and posterior simulation met hods. Several major application areas are covered: computer models, Bayesian clinical trial design, epidemiology, phylogenetics, bioinformatics, climate modelingand applications in political science, finance and marketing. As a review of current research in Bayesian analysis the book presents a balance between theory and applications. The lack of a clear demarcation between theoretical andapplied research is a reflection of the highly interdisciplinary and often applied nature of research in Bayesian stat istics. The book is intended as an update for researchers in Bayesian statistics, including non-statisticians whomake use of Bayesian inference to address substantive research questions in other fields. It would also be useful for graduate students and re search scholars in statistics or biostatistics who wish to acquaint themselves with currentresearch frontiers. Ming-Hui Chen is Professor of Statistics at the University of Connecticut Dipak K. Dey is Head and Professor of Statistics at the University of Connecticut Peter Mller is Professor of Biostatistics at theUniversity of Texas M. D. Anderson Cancer Center Dongchu Sun is Professor of Statistics at the University of Missouri- Columbia and Keyi
Note:Springer eBooks
Contents:Objective Bayesian Inference with Applications
Bayesian Decision Based Estimation and Predictive Inference
Bayesian Model Selection and Hypothesis Tests
Bayesian Inference for Complex Computer Models
Bayesian Nonparametrics and Semi
parametrics
Bayesian Influence and Frequentist Interface
Bayesian Clinical Trials
Bayesian Methods for Genomics, Molecular and Systems Biology
Bayesian Data Mining and Machine Learning
Bayesian Inference in Political Science, Finance, and Marketing Research
Bayesian Categorical Data Analysis
Bayesian Geophysical, Spatial and Tempora
ISBN:9781441969446
Series:e-books
Series:SpringerLink (Online service)
Series:Mathematics and Statistics (Springer-11649)
Keywords: Statistics , Mathematical statistics
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Call number:SPRINGER-2010-9781441916303:ONLINE Show nearby items on shelf
Title:Data Mining and Knowledge Discovery via Logic-Based Methods [electronic resource] : Theory, Algorithms, and Applications
Author(s): Evangelos Triantaphyllou
Date:2010
Publisher:Boston, MA : Springer US
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:The importance of having efficient and effective methods for data mining and knowledge discovery (DM) is rapidly growing. This is due to the wide use of fast and affordable computing power and data storage media and also thegathering of huge amounts of data in almost all aspects of human activity and interest. While numerous methods have been developed, the focus of this book presents algorithms and applications using one popular method that has beenformulated in terms of binary attributes, i.e., by Boolean functions defined on several attributes that are easily transformed into rules that can express new knowledge. This book presents methods that deal with key data mining andknowledge discovery issues in an intuitive manner, in a natural sequence, a nd in a way that can be easily understood and interpreted by a wide array of experts and end users. The presentation provides a unique perspective into theessence of some fundamental DM issues, many of which come from important real life applications such as breast cancer diagnosis. Applications and algorithms are accompanied by extensive experimental results and are presented in a waysuch that anyone with a minimum background in mathematics and computer science can benefit from the exposition. Rigor in m athematics and algorithmic development is not compromised and each chapter systematically offers some possibleextensions for future research
Note:Springer eBooks
Contents:Algorithmic Issues
Inferring a Boolean Function from Positive and Negative Examples
A Revised Branch
and
Bound Approach for Inferring a Boolean Function from Examples
Some Fast Heuristics for Inferring a Boolean Function from Examples
An Approach to Guided Learning of Boolean Functions
An Incremental Learning Algorithm for Inferring Boolean Functions
A Duality Relationship Between Boolean Functions in CNF and DNF Derivable from the Same Training Examples
The Rejectability Graph of Two Sets of Examples
Application Issues
The Reliability Issue in Data Mining: The Case
ISBN:9781441916303
Series:e-books
Series:SpringerLink (Online service)
Series:Springer Optimization and Its Applications, 1931-6828 : v43
Series:Mathematics and Statistics (Springer-11649)
Keywords: Mathematics , Computer science , Operations research
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Call number:SPRINGER-2009-9780387781938:ONLINE Show nearby items on shelf
Title:Cancer Mortality and Morbidity Patterns in the U.S. Population [electronic resource] : An Interdisciplinary Approach
Author(s): K.G Manton
Igor Akushevich
Julia Kravchenko
Date:2009
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:This book is the first of its kind to describe interdisciplinary approaches to biomedical studies. It views analyses of biomedical data sets, such as cancer morbidity and mortality, from a different and richer than classicepidemiological perspective by using mathematical modeling methods, including ones providing insights into probable mechanisms of human carcinogenesis. The book will be useful for many specialists, e.g., epidemiologists, oncologists,medical researchers, biologists, public health and environmental specialists, and specialists in mathematical modeling. Medical, biology and math undergraduates and postgraduates, as well as basic and applied researchers attempting toextend their studies in collaboration with other specialists in interdi sciplinary teams, will find practical information here. Biomedical specialists could be interested in historical aspects of cancer treatment and prevention,mechanisms of carcinogenesis, cancer risk factors, cancer mortality and morbidity trends in the U.S . over a more than 50-year period, as well as specific features of cancer histotypes, and recent approaches to cancer prevention.Readers interested in analytic aspects can find information on existing and innovative approaches used in interdisciplinary st udies such as stochastic process models, microsimulation of interventions, and empirical Bayes approaches.This book was written by authors with different backgrounds who teamed in an interdisciplinary group. Kenneth G. Manton, Ph.D. (Demography) is Resear ch Professor of Demographic Studies at Duke University (Durham, NC). He was Head ofthe W.H.O. Collaborating Center for Research and Training in the Methods of Assessing Risk and Forecasting Health Status Trends. He has authored more than 450 peer-reviewed publications, including several books. Igor Akushevich, Ph.D.(Theoretical and Mathematical Physics), Center for Population Health and Aging at Duke University, authored more than 70 peer-reviewed publi
Note:Springer eBooks
Contents:Preface
Introduction: Cancer contra human: cohabitation with casualties?
Cancer modeling: how far can we move?
Cancer risk factors
Standard and innovative statistical methods for empirically analyzing cancer morbidity and mortality
Stochastic methods of analysis
U.S. cancer morbidity and mortality risks
U.S. cancer morbidity: modeling age
patterns of cancer histotypes
Risk factors intervention
Cancer prevention
Conclusion/outlook
Appendices
ISBN:9780387781938
Series:e-books
Series:SpringerLink (Online service)
Series:Statistics for Biology and Health, 1431-8776
Series:Mathematics and Statistics (Springer-11649)
Keywords: Statistics , Oncology , Epidemiology , Bioinformatics , Demography
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Call number:SPRINGER-2008-9780387772400:ONLINE Show nearby items on shelf
Title:Bioconductor Case Studies [electronic resource]
Author(s): Florian Hahne
Wolfgang Huber
Robert Gentleman
Seth Falcon
Date:2008
Edition:1
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Bioconductor software has become a standard tool for the analysis and comprehension of data from high-throughput genomics experiments. Its application spans a broad field of technologies used in contemporary molecular biology. Inthis volume, the auth ors present a collection of cases to apply Bioconductor tools in the analysis of microarray gene expression data. Topics covered include * import and preprocessing of data from various sources * statisticalmodeling of differential gene expression * biolog ical metadata * application of graphs and graph rendering * machine learning for clustering and classification problems * gene set enrichment analysis Each chapter of this book describesan analysis of real data using hands-on example driven approaches. Sh ort exercises help in the learning process and invite more advanced considerations of key topics. The book is a dynamic document. All the code shown can be executedon a local computer, and readers are able to reproduce every computation, figure, and table . The authors of this book have longtime experience in teaching introductory and advanced courses to the application of Bioconductor software.Florian Hahne is a Postdoc at the Fred Hutchinson Cancer Research Center in Seattle, developing novel methodologi es for the analysis of high-throughput cell-biological data. Wolfgang Huber is a research group leader in the EuropeanMolecular Biology Laboratory at the European Bioinformatics Institute in Cambridge. He has wide-ranging experience in the development of methods for the analysis of functional genomics experiments. Robert Gentleman is Head of theProgram in Computational Biology at the Fred Hutchinson Cancer Research Center in Seattle, and he is one of the two authors of the original R system. Seth Falcon i s a member of the R core team and former project manager and developerfor the Bioconductor project
Note:Springer eBooks
Contents:The ALL Dataset
R and Bioconductor Introduction
Processing Affymetrix Expression Data
Two Color Arrays
Fold Changes, Log Ratios, Background Correction, Shrinkage Estimation, and Variance Stabilization
Easy Differential Expression
Differential Expression
Annotation and Metadata
Supervised Machine Learning
Unsupervised Machine Learning
Using Graphs for Interactome Data
Graph Layout
Gene Set Enrichment Analysis
Hypergeometric Testing Used for Gene Set Enrichment Analysis
Solutions to Exercises
ISBN:9780387772400
Series:e-books
Series:SpringerLink (Online service)
Series:Use R!
Series:Mathematics and Statistics (Springer-11649)
Keywords: Statistics , Bioinformatics , Biology Mathematics
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Call number:SPRINGER-2008-9780387759692:ONLINE Show nearby items on shelf
Title:Lattice [electronic resource] : Multivariate Data Visualization with R
Author(s): Deepayan Sarkar
Date:2008
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
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Note:R is rapidly growing in popularity as the environment of choice for data analysis and graphics both in academia and industry. Lattice brings the proven design of Trellis graphics (originally developed for S by William S.Cleveland and colleagues at Be ll Labs) to R, considerably expanding its capabilities in the process. Lattice is a powerful and elegant high level data visualization system that is sufficient for most everyday graphics needs, yetflexible enough to be easily extended to handle demands o f cutting edge research. Written by the author of the lattice system, this book describes it in considerable depth, beginning with the essentials and systematically delving intospecific low levels details as necessary. No prior experience with lattice is required to read the book, although basic familiarity with R is assumed. The book contains close to150 figures produced with lattice. Many of the examplesemphasize principles of good graphical design almost all use real data sets that are publicly availab le in various R packages. All code and figures in the book are also available online, along with supplementary material covering moreadvanced topics. Deepayan Sarkar won the 2004 John M. Chambers Statistical Software Award for writing lattice while he was a graduate student in Statistics at the University of Wisconsin-Madison. He is currently doing postdoctoralresearch in the Computational Biology program at the Fred Hutchinson Cancer Research Center, a member of the R Core Team, and an active participant on the R mailing lists
Note:Springer eBooks
Contents:Introduction
The anatomy of a Trellis display
Visualizing univariate distributions
Displaing multiway tables
Scatter plots and extensions
Trivariate displays
Specialized displays
Scales
Annotation
Devices, themes and other options
Conditioning
Manipulating the Trellis object
Augmenting Trellis displays
Writing panel functions
Creating new Trellis displays
A few tips and tricks
ISBN:9780387759692
Series:e-books
Series:SpringerLink (Online service)
Series:Use R!
Series:Mathematics and Statistics (Springer-11649)
Keywords: Statistics , Computer graphics , Visualization , Mathematical statistics
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Call number:SPRINGER-2008-9780387732992:ONLINE Show nearby items on shelf
Title:Optimization in Medicine [electronic resource]
Author(s): Carlos J. S Alves
Panos M Pardalos
Luis Nunes Vicente
Date:2008
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Optimization has become an essential tool in addressing the limitation of resources and need for better decision-making in the medical field. Both continuous and discrete mathematical techniques are playing an increasinglyimportant role in understand ing several fundamental problems in medicine. This volume presents a wide range of medical applications that can utilize mathematical computing. Examples include using an algorithm for considering the seedreconstruction problem in brachytherapy and using optimization-classification models to assist in the early prediction, diagnosis and detection of diseases. Discrete optimization techniques and measures derived from the theory ofnonlinear dynamics, with analysis of multi-electrode electroencephalographic (EEG) data, assist in predicting impending epileptic seizures. Mathematics in medicine can also be found in recent cancer research. Sophisticated mathematicalmodels and optimization algorithms have been used to generate treatment plans for radionuclide i mplant and external beam radiation therapy. Optimization techniques have also been used to automate the planning process in Gamma Knifetreatment, as well as to address a variety of medical image registration problems. This work grew out of a workshop on o ptimization which was held during the 2005 CIM Thematic Term on Optimization in Coimbra, Portugal. It provides anoverview of the state-of-the-art in optimization in medicine and will serve as an excellent reference for researchers in the medical computing community and for those working in applied mathematics and optimization
Note:Springer eBooks
Contents:The influence of dose grid resolution on beam selection strategies in radiotherapy treatment design
Decomposition of matrices and static multileaf collimators: a survey
Neuro
dynamic programming for fractionated radiotherapy planning
Randomized algorithms for mixed matching and covering in hypergraphs in 3D seed reconstruction in brachytherapy
Global optimization and spatial synchronization changes prior to epileptic seizures
Optimization
based predictive models in medicine and biology
Optimal reconstruction kernels in medical imaging
Optimal control in high intensity focu
ISBN:9780387732992
Series:e-books
Series:SpringerLink (Online service)
Series:Springer Optimization and Its Applications, 1931-6828 : v12
Series:Mathematics and Statistics (Springer-11649)
Keywords: Mathematics , Radiology, Medical , Mathematical optimization
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Call number:SPRINGER-2008-9780387686394:ONLINE Show nearby items on shelf
Title:Proportional Hazards Regression [electronic resource]
Author(s): John O'Quigley
Date:2008
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
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Note:The place in survival analysis now occupied by proportional hazards models and their generalizations is so large that it is no longer conceivable to offer a course on the subject without devoting at least half of the content tothis topic alone. This book focuses on the theory and applications of a very broad class of modelsproportional hazards and non-proportional hazards models, the former being viewed as a special case of the latterwhich underliemodern survival analysis. Unlike other books in this area the emphasis is not on measure theoretic arguments for stochastic integrals and martingales. Instead, while inference based on counting processes and the theory of martingalesis covered, much greater weight is placed on more traditional results such as the functional central limit theorem. This change in emphasis allows us in the book to devote much greater consideration to practical issues in modeling. Theimplications of different models, their practical interpretation, the predictive ability of any model, model construction, and model selection as well as the whole area of mis-specified models receive a great deal of attention. Thebook is aimed at both those interested in theory and those interested in applications. Many examples and illustrations are provided. The required mathematical and statistical background for those relatively new to the field iscarefully outlined so that the material is accessible to a broad range of levels. John OQuigleyDirector of Research at the French Institut National de la Sant et de la Recherche Mdicale and Professor of Mathematics at theUniversity of California at San Diegohas published extensively on the subject of survival analysis, both in theoretical and applied journals. He has taught and carried out collaborat ive research at several of the world's leadingdepartments of mathematics and statistics including the University of Washington, the Fred Hutchinson Cancer Research Center in Seattle,
Note:Springer eBooks
Contents:Introduction
Background: probability
Background: inference
Background: survival analysis
Marginal survival
Regression models and subject heterogeneity
Estimating equations
Inference: functions of the Brownian motion
Inference: likelihood
Inference: counting processes
Inference: small samples
Inference: changepoint models
Explained variation
Explained randomness
Survival given covariates
Proofs of theorems, lemmas and corollaries
ISBN:9780387686394
Series:e-books
Series:SpringerLink (Online service)
Series:Statistics for Biology and Health, 1431-8776
Series:Mathematics and Statistics (Springer-11649)
Keywords: Statistics , Econometrics
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Call number:SPRINGER-2007-9780387377407:ONLINE Show nearby items on shelf
Title:Nanobiotechnology of Biomimetic Membranes [electronic resource]
Author(s): Donald K Martin
Date:2007
Publisher:Boston, MA : Springer US
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:About the Series: Fundamental Biomedical Technologies features titles in multidisciplinary, technology-driven areas, providing the foundations for breakthrough advances in medicine and biology. The term technology refers, in avigorously unrestrictive sense, to a broad array of engineering disciplines, the sciences of computation and informatics, mathematical models exploiting and advancing methods of mathematical physics, and the development of novel,experimental discovery devices. Titles in this ser ies are designed and selected to provide high-level visionary input for specialists, while presenting overviews of emerging fields for those in related areas. Volumes in this series aimto provide technologists with the material to gain competent entry int o biomedical research and biomedical researchers to understand and embrace novel technological foundations and tools. About the Series Editor: Mauro Ferrari is aprofessor in the Brown Institute of Molecular Medicine, a professor of internal medicine in th e division of cardiology, and the chairman of the department of biomedical engineering at the University of Texas Health Science Center inHouston, Texas. He holds concurrent professor appointments at the M.D. Anderson Cancer Center as professor of experim ental therapeutics, and at Rice University in bioengineering. Dr. Ferrari is the current President of the Alliance forNanoHealth and he has spearheaded the development of the National Cancer Institutes nanotechnology programs. Dr. Ferrari is also the foun der and Editor-in-Chief of Springers archival journal Biomedical Microdevices.Nanobiotechnology of Biomimetic Membranes Donald Martin, Editor Nanobiotechnology of Biomimetic Membranes focuses on biomimetic membranes, one of the fundamental building blocks of nanobiotechnology. The application of nanotechnologyprinciples and methodology to problems in biotechnology provides an exciting new discipline that will generate a revolution of novel applica
Note:Springer eBooks
Contents:The Significance of Biomimetic Membrane Nanobiotechnology to Biomedical Applications
Langmuir
Blodgett technique for Synthesis o fbiomimetic lipid membranes
Liposome techniques for synthesis of biomimetic lipid membranes
Characterization and analysis of biomimetic membranes
Biomimetic membranes in biosensor applications
ISBN:9780387377407
Series:e-books
Series:SpringerLink (Online service)
Series:Fundamental Biomedical Technologies, 1559-7083 : v1
Series:Physics and Astronomy (Springer-11651)
Keywords: Medicine , Cytology , Biomedical engineering , Nanotechnology
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Call number:SPRINGER-2006-9780387358512:ONLINE Show nearby items on shelf
Title:Universality of Nonclassical Nonlinearity [electronic resource] : Applications to Non-Destructive Evaluations and Ultrasonic
Author(s): Pier Paolo Delsanto
Date:2006
Publisher:New York, NY : Springer New York
Size:1 online resource
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Note:This book comes as a result of the research work developed in the framework of two international projects: the European Science Foundation supported program NATEMIS (Nonlinear Acoustic Techniques for Micro-Scale DamageDiagnostics) and a Los Alamos-ba sed international network. The main topics of both the programs and the book cover the phenomenology, theory and applications of Nonclassical Nonlinearity (NCNL). NCNL techniques have been found inrecent years to be extremely powerful (up to 1000 times mo re than the corresponding linear techniques) in a wide range of applications, including Material Characterization, Ultrasonics, Geophysics and Maintenance and Restoration ofartifacts. These techniques are being adopted as the main inspection and research tool in another European program: AERONEWS (Health monitoring of aircraft by nonlinear elastic wave propagation). In the future, the proposedUniversality of NCNL is expected to extend the range of applications to numerous other fields and scientific disci plines outside acoustics and NDE
Note:Springer eBooks
Contents:Towards a top
down approach in materials science
Nonlinear dynamical systems in economics
Nonlinearity in medical sciences (oncology)
Nonlinearity as a structural feature of living systems
Nonlinearity and complexity in Elastic Wave Motion
The state of the art of nonlinear elasticity in geomaterials
Nonlinear Rock Mechanics Seasonality and Harvesting, Revisited
Cancer growth is a nonclassical nonlinear phenomenon
Multiscale Approach to Nonlinear and Hysteretic Elastodynamics in one
and two
dimensions
Inverse modelling of microdamage characteristics in specimens of s
ISBN:9780387358512
Series:e-books
Series:SpringerLink (Online service)
Series:Physics and Astronomy (Springer-11651)
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Call number:SPRINGER-2006-9780387354293:ONLINE Show nearby items on shelf
Title:Statistical Analysis of Environmental Space-Time Processes [electronic resource]
Author(s): Nhu D Le
James V Zidek
Date:2006
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:This book provides a broad introduction to the fascinating subject of environmental space-time processes addressing the role of uncertainty. Within that context, it covers a spectrum of technical matters from measurement toenvironmental epidemiology to risk assessment. It showcases non-stationary vector-valued processes, while treating stationarity as a special case. The contents reflect the authors cumulative knowledge gained over many years ofconsulting and research collaboration. In particular, wi th members of their research group, they developed within a hierarchical Bayesian framework, the new statistical approaches presented in the book for analyzing, modeling, andmonitoring environmental spatio-temporal processes. Furthermore they indicate new directions for development. This book contains technical and non-technical material and it is written for statistical scientists as well as consultants,subject area researchers and students in related fields. Novel chapters present the authors hierarchic al Bayesian approaches to spatially interpolating environmental processes designing networks to monitor environmental processesmultivariate extreme value theory incorporating risk assessment. In addition, they present a comprehensive and critical survey o f other approaches, highlighting deficiencies that their method seeks to overcome. Special sections markedby an asterisk provide rigorous development for readers with a strong technical background. Alternatively readers can go straight to the tutorials su pplied in chapter 14 and learn how to apply the free, downloadable modeling and designsoftware that the authors and their research partners have developed. Nhu Le is a Senior Scientist in Cancer Control Research and a former Director of the Occupational O ncology Research Program at the British Columbia Cancer Agency(BCCA). An Adjunct Professor of Statistics at the University of British Columbia since 1992, he also teaches graduate courses and sup
Note:Springer eBooks
Contents:First encounters
Case study
Uncertainty
Measurement
Modelling
Covariances
Classical approaches
Bayesian kriging
Hierarchical methods
Multivariate modelling
Network design
Extremes
Risk assessment
R tutorial
ISBN:9780387354293
Series:e-books
Series:SpringerLink (Online service)
Series:Springer Series in Statistics, 0172-7397
Series:Mathematics and Statistics (Springer-11649)
Keywords: Statistics , Epidemiology , Mathematical statistics , Environmental toxicology
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Call number:SPRINGER-2006-9780387254449:ONLINE Show nearby items on shelf
Title:Quantitative Analysis in Nuclear Medicine Imaging [electronic resource]
Author(s): Habib Zaidi
Date:2006
Publisher:Boston, MA : Springer US
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:This book provides a review of image analysis techniques as they are applied in the field of diagnostic and therapeutic nuclear medicine. Driven in part by the remarkable increase in computing power and its ready and inexpensiveavailability, this is a relatively new yet rapidly expanding field. Likewise, although the use of radionuclides for diagnosis and therapy has origins dating back almost to the discovery of natural radioactivity itself, radionuclidetherapy and, in particular, targeted radionucl ide therapy has only recently emerged as a promising approach for therapy of cancer and, to a lesser extent, other diseases. As effort has, therefore, been made to place the reviewsprovided in this book in a broader context. The effort to do this is refle cted by the inclusion of introductory chapters that address basic principles of nuclear medicine imaging, followed by overview of issues that are closely relatedto quantitative nuclear imaging and its potential role in diagnostic and therapeutic applicati ons. The different chapters discuss the basic principles and various steps required for obtaining quantitatively accurate data from nuclearmedicine images including data collection methods and algorithms used to correct them for physical degrading factors (e.g. collimator response, attenuation, scatter, partial volume effect), and image reconstruction algorithms(analytic, iterative) as well as image processing and analysis techniques as their clinical and research applications in neurology, cardiology and oncology. Some algorithms are described and illustrated with some useful features andclinical applications. Other potential applications of quantitative image analysis such as image-guided radiation therapy are also discussed
Note:Springer eBooks
Contents:Preface
Overview of nuclear medical imaging: physics and instrumentation
Dual
modality imaging: more than the sum of its parts
Analytic image reconstruction methods
Iterative image reconstruction methods
Collimator
detector response compensation in SPECT
Attenuation correction strategies in emission tomography
Scatter correction strategies in emission tomography
Correction of partial volume effects in emission tomography
Image registration techniques in nuclear medicine imaging
Image segmentation techniques in nuclear medicine imaging
Monte Carlo modeling in nucl
ISBN:9780387254449
Series:e-books
Series:SpringerLink (Online service)
Series:Physics and Astronomy (Springer-11651)
Keywords: Neurosciences , Toxicology , Cardiology , Oncology , Biomedical engineering
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Call number:SPRINGER-2005-9780387293622:ONLINE Show nearby items on shelf
Title:Bioinformatics and Computational Biology Solutions Using R and Bioconductor [electronic resource]
Author(s): Robert Gentleman
Vincent J Carey
Wolfgang Huber
Rafael A Irizarry
Sandrine Dudoit
Date:2005
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Bioconductor is a widely used open source and open development software project for the analysis and comprehension of data arising from high-throughput experimentation in genomics and molecular biology. Bioconductor is rooted inthe open source statis tical computing environment R. This volume's coverage is broad and ranges across most of the key capabilities of the Bioconductor project, including importation and preprocessing of high-throughput data frommicroarray, proteomic, and flow cytometry platfo rms curation and delivery of biological metadata for use in statistical modeling and interpretation statistical analysis of high-throughput data, including machine learning andvisualization, modeling and visualization of graphs and networks. The developer s of the software, who are in many cases leading academic researchers, jointly authored chapters. All methods are illustrated with publicly available data,and a major section of the book is devoted to exposition of fully worked case studies. This book is more than a static collection of descriptive text, figures, and code examples that were run by the authors to produce the text it is adynamic document. Code underlying all of the computations that are shown is made available on a companion website, and re aders can reproduce every number, figure, and table on their own computers. Robert Gentleman is Head of theProgram in Computational Biology at the Fred Hutchinson Cancer Research Center in Seattle. He is one of the two authors of the original R system and a leading member of the R core team. Vincent Carey is Associate Professor of Medicine(Biostatistics), Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School. Gentleman and Carey are co-founders of the Bioconductor project. Wolfgang Hub er is Group Leader in the European Molecular Biology Laboratory atthe European Bioinformatics Institute in Cambridge. He has made influential contributions to the error modeling of microarray data. Raf
Note:Springer eBooks
Contents:Preprocessing data from genomic experiments
Preprocessing Overview
Preprocessing High
density Oligonucleotide Arrays
Quality Assessment of Affymetrix GeneChip Data
Preprocessing Two
Color Spotted Arrays
Cell
Based Assays
SELDI
TOF Mass Spectrometry Protein Data
Meta
data: biological annotation and visualization
Meta
data Resources and Tools in Bioconductor
Querying On
line Resources
Interactive Outputs
Visualizing Data
Statistical analysis for genomic experiments
Analysis Overview
Distance Measures in DNA Microarray Data Analysis
Cluster Analysis of
ISBN:9780387293622
Series:e-books
Series:SpringerLink (Online service)
Series:Statistics for Biology and Health, 1431-8776
Series:Mathematics and Statistics (Springer-11649)
Keywords: Statistics , Bioinformatics , Animal genetics
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Call number:SPRINGER-2005-9780387260150:ONLINE Show nearby items on shelf
Title:Molecular and Cellular Signaling [electronic resource]
Author(s): Martin Beckerman
Date:2005
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:A small number of signaling pathways, no more than a dozen or so, form a control layer that is responsible for all signaling in and between cells of the human body. The signaling proteins belonging to the control layer determinewhat kinds of cells ar e made during development and how they function during adult life. Malfunctions in the proteins belonging to the control layer are responsible for a host of human diseases ranging from neurological disorders tocancers. Most drugs target components in the control layer, and difficulties in drug design are intimately related to the architecture of the control layer. Molecular and Cellular Signaling provides an introduction to molecular andcellular signaling in biological systems with an emphasis on the unde rlying physical principles. The text is aimed at upper-level undergraduates, graduate students and individuals in medicine and pharmacology interested in broadeningtheir understanding of how cells regulate and coordinate their core activities and how dise ases arise when these regulatory systems malfunction, as well as those in chemistry, physics and computer science interested in pursuing careersin biological and medical physics, bioinformatics and systems biology. To that end, the book includes backgroun d information and review sections, and chapters on signaling in the immune, endocrine (hormonal) and nervous systems. It haschapters on cancer, apoptosis and gene regulation, and contains chapters on bacteria and viruses. In those chapters not specificall y devoted to pathogens, connections between diseases, drugs and signaling are made. Each chapter alsofeatures a problem set to facilitate further discussion and understanding. About the Author: Martin Beckerman, Ph.D. is Senior Scientist at the Center for Martin Beckerman, PhD, is a senior research scientist at the Department ofEnergy/National Nuclear Security Administrations Y-12 National Security Complex in Oak Ridge, TN. Prior to assuming his curre
Note:Springer eBooks
Contents:1. Introduction
2. The Control Layer
3. Exploring Protein Structure and Function
4. Macromolecular Forces
5. Protein Folding and Binding
6. Stress and Pheromone Responses in Yeast
7. Two
Component Signaling Systems
8. Organization of Signal Complexes by Lipids, Calcium and Cyclic Amp
9. Signaling by Cells of the Immune System
10. Cell Adhesion and Motility
11. Signaling in the Endocrine System
12. Signaling in the Endocrine and Nervous System through GPCRs
13. Cell Fate and Polarity
14.Cancer
15. Apoptosis
16. Gene Regulation in Eukaryotes
17. Ce
ISBN:9780387260150
Series:e-books
Series:SpringerLink (Online service)
Series:Biological and Medical Physics, Biomedical Engineering, 1618-7210
Series:Physics and Astronomy (Springer-11651)
Keywords: Medicine , Biochemistry , Cytology , Biomedical engineering
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Call number:SPRINGER-2004-9783642186875:ONLINE Show nearby items on shelf
Title:Life Sciences and Radiation Accomplishments and Future Directions
Author(s):
Date:2004
Size:1 online resource (285 p.)
Note:10.1007/978-3-642-18687-5
Contents:Introductory Remarks: On the State of Radiation Research -- Cellular Responses, Genomic Stability -- Cellular Responses to DNA Damage — a Personal Account -- Prospects for Research in Radiation Biology -- Cellular and Molecular
Aspects of the Anti-inflammatory Action of Low Dose Ionizing Irradiation -- The Network of Radiation Responses and Genomic Stability -- Topological Factors in Radiation Biology -- Signalling -- Molecular Radiation Biology -
Perspectives for the Future -- P53 Stabilization and the Role of Radiation-Induced Signalling -- Cytogenetics -- Molecular Genetic Mechanisms of Radiocarcinogenesis and Predictive Markers for Radioresistance in Tumors — Present Work
and Future Perspectives — -- FISH and CHIPs: Colorful Clues to Radiation-Induced Chromosomal Instability -- Carcinogenesis, Radiation Protection -- Recombination and Radiation-Induced Cancer. Mechanisms and Genetic Testing --
UV-Radiation Biology as Part of Cancer Research -- Contribution of Radiation Research to Human Space Exploration: Approaches to mitigate Radiation Health Risk in Spaceflight -- Repair -- Radiation Damage and Human Cells: You have to
know one to understand the other -- Different Means to an End: DNA Double-Strand Break Repair -- Impact of Physical Developments -- Electrostatistics of DNA Complexes -- Future Radiobiology at Accelerators: From Heavy Ion Therapy to
Basic Research -- Targeting Radiation at the Subcellular, Cellular and Tissue Levels: Future Strategies -- The PTB — a Competent and Reliable Partner for Research and Development Projects in the Field of Ionizing Radiation -- General
Issues -- Life Sciences and Radiation Research - Examples from the Past -- Need and Importance of Further Research in the Field of Radiation -- Reflections on the Acceptability of the Use of Ionizing Radiation to German Society --
Janus Face of Radiation Biology and Science for the Future -- Postscript: Thoughts on the Future of Radiation Research and its Impact on Life Sciences
ISBN:9783642186875
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Physics , Radiotherapy , Cell biology , Biophysics , Biological physics , Physics , Biophysics and Biological Physics , Radiotherapy , Cell Biology
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Call number:SPRINGER-2003-9783642557217:ONLINE Show nearby items on shelf
Title:Exploratory Data Analysis in Empirical Research Proceedings of the 25th Annual Conference of the Gesellschaft für Klassifikation e.V., University of Munich, March 14–16, 2001
Author(s):
Date:2003
Size:1 online resource (536 p.)
Note:10.1007/978-3-642-55721-7
Contents:1: Classification, Data Analysis and Statistics -- Sliced Inverse Regression for High-dimensional Time Series -- Symbolic Clustering of Constrained Probabilistic Data -- On Memory Requirement with Normal Symbolic Form -- On the Roles
of Galois Connections in Classification -- Mining Sets of Time Series: Description of Time Points -- Spatial Smoothing with Robust Priors in Functional MRI -- Clustering in the Presence of Outliers -- Two Models of Random Intersection
Graphs for Classification -- Classification Techniques based on Methods of Computational Intelligence -- Constrained Correspondence Analysis for Seriation in Archaeology Applied to Sagalassos Ceramic Tablewares -- The Moment
Preservation Method of Cluster Analysis -- On The General Distance Measure -- Tests for One-dimensional Nearest Neighbors Clusters -- Integration of Cluster Analysis and Visualization Techniques for Visual Data Analysis -- Bayesian
Space-time Analysis of Health Insurance Data -- On Clustering by Mixture Models -- Using Additive Conjoint Measurement in Analysis of Social Network Data -- Bayesian Latent Class Metric Conjoint Analysis — A Case Study from the
Austrian Mineral Water Market -- Diagnostics in Multivariate Data Analysis: Sensitivity Analysis for Principal Components and Canonical Correlations -- Classification of Natural Languages by Word Ordering Rule -- Combining Mental Fit
and Data Fit for Classification Rule Selection -- Bayesian Analysis of Econometric Models for Count Data: A Survey -- k-Means Clustering with Outlier Detection, Mixed Variables and Missing Values -- 2: Web Mining, Data Mining and
Computer Science -- Repeat-buying Theory and its Application for Recommender Services -- Joker — Visualization of an Object Model for a Cost Accounting Educational Software -- Data Preparation in Large Real-world Data Mining Projects:
Methods for Imputing Missing Values -- Clustering of Document Collections to Support Interactive Text Exploration -- Web Usage Mining — Languages and Algorithms -- Thesaurus Migration in Practice -- Relational Clustering for the
Analysis of Internet Newsgroups -- The Theory of On-line Learning — A Statistical Physics Approach -- A Framework for Web Usage Mining on Anonymous Logfile Data -- 3: Medicine, Biological Sciences and Health -- Knee Replacement Surgery
and Learning Effects — Data Evidence from a German Hospital -- Self-organizing Maps and its Applications in Sleep Apnea Research and Molecular Genetics -- Automated Classification of Optic Nerve Head Topography Images for Glaucoma
Screening -- Comparing Split Criteria for Constructing Survival Trees -- A Type of Bayesian Small Area Estimation for the Analysis of Cancer Mortality Data -- DEA-Benchmarks for Austrian Physicians -- Data Mining Tools for Quality
Management in Health Care -- The Effects of Simultaneous Misclassification on the Attributable Risk -- Statistical Genetics — Present and Future -- 4: Marketing, Finance and Management Science -- Market Simulation Using Bayesian
Procedures in Conjoint Analysis -- Value Based Benchmarking and Market Partitioning -- Optimization of Corporate Reorganization Portfolios based on a Genetic Algorithm -- Key Success Factors in City Marketing — Some Empirical Evidence
-- From Credit Scores to Stable Default Probabilities: A Model Based Approach -- Dimensions of Credit Risk -- Cognitive Organization of Person Attributes: Measurement Procedures and Statistical Models -- Manufacturing Branches in
Poland — A Classification Attempt -- Market-Segments of Automotive Brands: Letting Multivariate Analyses Reveal Additional Insights -- Sequence Mining in Marketing -- Portfolio Management Using Multivariate Time Series Forecasts --
Value-at-Risk for Financial Assets Determined by Moment Estimators of the Tail Index -- Keywords -- Authors
ISBN:9783642557217
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Computer science , Business , Management science , Data structures (Computer science) , Database management , Probabilities , Statistics , Economic theory , Computer Science , Database Management , Probability Theory and Stochastic Processes , Business and Management, general , Data Structures, Cryptology and Information Theory , Statistics for Business/Economics/Mathematical Finance/Insurance , Economic Theory/Quantitative Economics/Mathematical Methods
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Call number:SPRINGER-2003-9780387218663:ONLINE Show nearby items on shelf
Title:Design and Analysis of DNA Microarray Investigations
Author(s): Richard M Simon
Date:2003
Size:1 online resource (19 p.)
Note:10.1007/b97583
Contents:DNA Microarray Technology -- Design of DNA Microarray Experiments -- Image Analysis -- Quality Control -- Array Normalization -- Class Comparison -- Class Prediction -- Class Discovery
ISBN:9780387218663
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Medicine , Cancer research , Molecular biology , Pharmacology , Health informatics , Bioinformatics , Statistics , Biomedicine , Cancer Research , Bioinformatics , Statistics for Life Sciences, Medicine, Health Sciences , Molecular Medicine , Pharmacology/Toxicology , Health Informatics
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Call number:SPRINGER-2002-9783642559914:ONLINE Show nearby items on shelf
Title:Classification, Automation, and New Media Proceedings of the 24th Annual Conference of the Gesellschaft für Klassifikation e.V., University of Passau, March 15—17, 2000
Author(s):
Date:2002
Size:1 online resource (535 p.)
Note:10.1007/978-3-642-55991-4
Contents:1: Data Analysis, Statistics, and Classification -- Clustering and Models -- Some New and Some Old Results for the Polytomous Rasch Model -- Some Basic Results on the Extension of Quasi-likelihood Based Measurement Error Correction to
Multivariate and Flexible Structural Models -- On the Optimal Number of Clusters in Histogram Clustering -- The Dual Dynamic Factor Analysis Models -- Joint Non-symmetrical Correspondence Analysis with Ordered Categories -- Regression
Analysis of Extremely Multicollinear Data -- Modern Data Analysis: A Clash of Paradigms -- Two-mode Clustering with Genetic Algorithms -- Exact Tests for the Comparison of Binary Data Structures in Time -- Connected Maximum Split
Clustering of Ladder Graphs -- A Generalization of Two-mode Three-way Asymmetric Multidimensional Scaling -- Central Limit Theorem for Probabilities of Correct Classification -- A New Model for the Analysis of Multitrait-multimethod
Data -- Discrete and Continuous Models for Two-way Data -- 2: Pattern Recognition and Automation -- Towards Feature Fusion — A Classifier on the Basis of Automatically Generated Significant Contour Sections -- Convex Discriminant
Analysis Tools for Non Convex Pattern Recognition -- Sparse Kernel Feature Analysis -- 3: Data Mining, Information Processing, and Automation -- Exploring Association Rules by Interactive Graphics -- Classification of Texts with
Support Vector Machines: An Examination of the Efficiency of Kernels and Data-transformations -- Text Mining with the Help of Cohesion Trees -- New Features of Categorical Principal Components Analysis for Complicated Data Sets,
Including Data Mining -- Supplement of Information: Data Integration by Classification of Pairs of Records -- The Completion of Missing Values by Neural Nets for Data Mining -- Knowledge Landscapes: Clustering Hypermedia Course Content
for Efficient Overviews -- Simplification of Knowledge Discovery using “Structure Classification” -- 4: New Media, Web Mining, and Automation -- Natural Language-based Specification and Fuzzy Logic for the Multimedia Development
Process -- A Tool System for an Object-oriented Approach to Construction and Maintenance of Hypermedia Documents -- Recommendations for Virtual Universities from Observed User Behavior -- Virtual Dialect Areas in the Internet:
“Townchats” -- The Navigation Problem in the World-Wide-Web -- Mining Web Usage Data for Automatic Site Personalization -- Integrating Combinatorial Relationships in a Cartography for Web Site Promotion -- 5: Applications in Management
Science, Finance, and Marketing -- Common Due Date Scheduling — Straddling Jobs and Due Windows — -- Currency Derivatives in German Non-financials: Empirical Evidence on Theoretical Approaches -- Data Visualization and Preparation by
Separating Sales Force Data -- Fuzzy Scenario Evaluation -- Fair Stock Risk Premiums under Firm-specific Price Jumps -- What Components Determine Stock Market Returns in the 1990’s? -- A Comparison of Estimators for Multivariate ARCH
Models -- Pricing of a New Integrated Risk Reinsurance Product -- A Multiple Method Approach for Discrimination and Classification in Marketing Research -- Goodness-of-Fit Measures for Two-mode Cluster Analyses -- On Volatility
Transfers During the Asia Crisis in 1997-1998 -- 6: Applications in Medicine, Biology, Archaeology, and Others -- QTL Mapping in Plant Populations -- Robust Multivariate Methods in Geostatistics -- Resampling Methods in Physical
Mapping -- Validating Dialect Comparison Methods -- Rater Classification on the Basis of Latent Features in Responding to Situations -- Results of Automatic Conversion of Diagnoses from ICD-9 to ICD-10 for Cancer Registration --
Exploring Roman Brick and Tile by Cluster Analysis with Validation of Results -- Relief Intensity and the Formation of the Archaeological Record -- Spatio-Temporal Modeling of Cancer Mortality Rates -- The Classification of Critical
Periods for Melanoma Development due to UV-Radiation -- Classification in the Prescription of Medicaments -- Effects of Independent Non-differential Misclassification on the Attributable Risk -- A New Approach to Discriminant Analysis
with Longitudinal Data -- Author Index
ISBN:9783642559914
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Computer science , Information technology , Business , Data structures (Computer science) , Coding theory , Pattern recognition , Statistics , Econometrics , Computer Science , Data Structures, Cryptology and Information Theory , Coding and Information Theory , Econometrics , IT in Business , Statistics for Business/Economics/Mathematical Finance/Insurance , Pattern Recognition
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Call number:SPRINGER-2002-9780387216058:ONLINE Show nearby items on shelf
Title:Cancer Precursors Epidemiology, Detection, and Prevention
Author(s):
Date:2002
Size:1 online resource (430 p.)
Note:10.1007/b97323
Contents:Site-Specific Precancerous Conditions -- Biological Basis of Carcinogenesis -- Mechanisms and Biological Markers of Carcinogenesis -- Morphology of Cancer Precursor Lesions -- Issues Related to Measurement and Interpretation of Cancer
Precursors -- Collection, Processing, and Analysis of Preneoplastic Specimens -- Intermediate Markers in Cancer Research: Theoretical and Practical Issues in the Use of Surrogate Endpoints -- Assessing Epidemiological Relations and the
Role of Measurement Errors -- Site-Specific Precancerous Conditions -- Upper Aerodigestive Tract -- Esophagus -- Stomach -- Colon and Rectum -- Anus -- Liver -- Pancreas -- Lung -- Skin -- Breast -- Cervix -- Endometrium -- Ovary --
Vulva and Vagina -- Prostate -- Bladder -- Control of Cancer Precursors -- Screening -- Chemoprevention -- Evidence-Based Policy Recommendations on Screening and Prevention -- Conclusion -- Prospects
ISBN:9780387216058
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Medicine , Cancer research , Health promotion , Oncology , Epidemiology , Medicine & Public Health , Oncology , Epidemiology , Health Promotion and Disease Prevention , Cancer Research
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Call number:SPRINGER-2001-9781461512530:ONLINE Show nearby items on shelf
Title:Telemedicine Medicine and Communication
Author(s):
Date:2001
Size:1 online resource (213 p.)
Note:10.1007/978-1-4615-1253-0
Contents:1: Tele-Imaging -- Computer Supported Cooperative 3D Teleimaging in Java -- 3D Image Based Collaboration System for Telemedicine -- Computer Mediated Communication of Medical Image Data: An Example from Cardiological Ultrasound Data
-- Digital Image Communication in Radiotherapy -- The Challenge of Telepathology -- Improvement of Fetal Diagnostics Using Telepathology -- 2: Clinical Applications -- Telearchiving for Craniosynostosis Research -- A Case Study for
Digital Systems Integration and Telemedicine in the Management of Lung Cancer Treatment -- Neurovisual Rehabilitation via the Internet -- Knowledge Management in Field of Radiology -- 3: Platforms and Medical Networks -- The
Telemedicine Project of the Medical Service of the Bundeswehr -- Integrated Health Care Within the Compound Network Bottrop -- ONCONET: A Telematics Application Programme Projects Result -- Integration Of TLS In An
Internet/intranet-based Application -- Virtual Polyclinic -- 4: Medical Data Transfer -- The Next Generation Internet (NGI) for Telemedicine Applications -- VESIMA-MED -- 5: Standardisation and Data Compression -- Applicability of
Lossy Image Data Compression in Tele-Medicine -- Standardization of Image Collaboration Command Protocol for Tele-Medicine
ISBN:9781461512530
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Physics , Computer science , Biophysics , Biological physics , Statistics , Social sciences , Physics , Biophysics and Biological Physics , Social Sciences, general , Statistics for Life Sciences, Medicine, Health Sciences , Computer Science, general , Information Systems Applications (incl. Internet)
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Call number:SPRINGER-2000-9783642572807:ONLINE Show nearby items on shelf
Title:Classification and Information Processing at the Turn of the Millennium Proceedings of the 23rd Annual Conference of the Gesellschaft für Klassifikation e.V., University of Bielefeld, March 10–12, 1999
Author(s):
Date:2000
Size:1 online resource (492 p.)
Note:10.1007/978-3-642-57280-7
Contents:1: Data Analysis and Classification -- New Developments in Latent Variable Models -- Regression-Type Models for Kohonen’s Self-Organizing Networks -- Relational Data Analysis, Discrimination and Classification -- Data Types and
Information: Beyond the Current Practice of Data Analysis -- Two-Mode Three-Way Asymmetric Multidimensional Scaling with Constraints on Asymmetry -- Regularized Discriminant Analysis with Optimally Scaled Data -- Recurrence Properties
in Two-Mode Hierarchical Clustering -- On Pyramidal Classification in the Delimitation of Climatic Regions in Catalonia -- On the Modal Understanding of Triadic Contexts -- Clustering and Scaling: Grouping Variables in Burt Matrices --
Standardisation of Data Set under Different Measurement Scales -- Neural Networks for Two-Group Classification Problems with Monotonicity Hints -- A Bridge from the Nearest Neighbour to the Fixed Bandwidth in Nonparametric Functional
Estimation -- Clustering Techniques for the Detection of Business Cycles -- Simulated Annealing Optimization for Two-mode Partitioning -- 2: Computer Science, Computational Statistics, and Data Mining -- Competitiveness of Evolutionary
Algorithms -- Intelligent Data Analysis via Linguistic Data Summaries: A Fuzzy Logic Approach -- Algorithm Selection Support for Classification -- Society of Knowledge — Interdisciplinary Perspectives of Information Processing in
Virtual Networks -- What is Computational Statistics? -- A Development Framework for Nature Analogic Heuristics -- Systematizing and Evaluating Data Mining Methods -- On Textures: A Sketch of a Texture-Based Image Segmentation Approach
-- Automatic Texture Classification by Visual Properties -- Java Servlets versus CGI — Implications for Remote Data Analysis -- Generating Automatically Local Feature Groups of Complex and Deformed Objects -- Decision Tree Construction
by Association Rules -- Learning Complex Similarity Measures -- Graphical Programming in Statistics: The XGPL Prototype -- 3: Management Science, Marketing, and Finance -- Measuring Brand Loyalty on the Individual Level: a Comparative
Study -- Facility Location Planning with Qualitative Location Factors -- Testing the Multinomial Logit Model -- Time Optimal Portfolio Selection: Mean-variance-efficient Sets for Arithmetic and Geometric Brownian Price Processes --
Analyzing Multigroup Data with Structural Equation Models -- Validity of Customized and Adaptive Hybrid Conjoint Analysis -- Analysis of the Assessments of One’s Values Among Different Cohorts in Age and Sex by Multidimensional Scaling
-- Impacts of Hedging with Futures on Optimal Production Levels -- How to Integrate Stock Price Jumps into Portfolio Selection -- A Multivariate GARCH-M Model for Exchange Rates in the US, Germany and Japan -- A Model for Constructing
Quadratic Objective Functions and its Applications to Price Adjustments -- 4: Biology, Genome Analysis, and Medicine -- Phylogeny Inference by Minimum Conflict -- Detecting Change-Points in Aircraft Noise Effects -- A Generalized
Estimating Equations Approach to Quantifying the Influence of Meteorological Conditions on Hand Dermatitis -- Discrimination in Paired Data Situations -- Classification of Multidimensional Visual Field Data for Glaucoma Diagnosis --
Quality of Life of Cancer Patients: A Multi-set Analysis -- A New Approach on Nonparametric Repeated Measures Analysis of Variance -- 5: Text Analysis and Information Retrieval -- GERHARD (German Harvest Automated Retrieval and
Directory) -- Automatic Labelling of References for Internet Information Systems -- Architecture and Retrieval Methods of a Search Assistant for Scientific Libraries -- Computer Aided Evaluations of Linguistic Atlases: Prom Automatic
Classification to Dialectometry -- Structured Phrases for Indexing and Retrieval of Research Topics -- Author and Subject Index
ISBN:9783642572807
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Computer science , Information technology , Business , Data structures (Computer science) , Probabilities , Statistics , Econometrics , Computer Science , Data Structures, Cryptology and Information Theory , Econometrics , IT in Business , Statistics for Business/Economics/Mathematical Finance/Insurance , Probability Theory and Stochastic Processes
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Call number:SPRINGER-1996-9789400902176:ONLINE Show nearby items on shelf
Title:Mass Spectrometry in Biomolecular Sciences
Author(s):
Date:1996
Size:1 online resource (523 p.)
Note:10.1007/978-94-009-0217-6
Contents:I: Methods in Mass Spectrometry -- 1. Ion Formation by Fast Atom Bombardment Mass Spectrometry -- 2. Matrix-Assisted Laser Desorption-Ionization (MALDI) Mass Spectrometry of Biological Molecules -- 3. Matrix-Assisted Laser Desorption
Mass Spectrometry on a Magnetic Sector Instrument Fitted with an Array Detector -- 4. Electrospray Ionization Mass Spectrometry: Protein Structure -- 5. Applications of Quantum Chemistry in Mass Spectrometry -- 6. Proton Affinities and
Intrinsic Basicities of Alanine and Glycine Studied by Means of AM1 and PM3 Methods -- II: Instrumentation for Mass Analysis and Detection -- 7. Energy-Isochronous Time-of-Flight Mass Spectrometers -- 8. The Detection of High
Mass-to-Charge Biological Ions by Fourier Transform Mass Spectrometry: Issues and Routes for Instrument Improvement -- 9. Quadrupole Mass Filters, Quadrupole Ion Traps and Fourier Transform Ion Cyclotron Resonance Spectrometers -- 10.
Energy Shifts in Collisional Activation -- 11. Hybrid Instruments of Unusual Geometry -- III: Application to Biomolecules -- 12. Continuous-Flow Fast Atom Bombardment Mass Spectrometry: Applications to Dynamic Systems -- 13. Hybrid
Tandem Mass Spectrometry of Peptides -- 14. Mass Spectrometry in the Study of Advanced Glycation End Products -- 14. Nucleic Acids: Overview and Analytical Strategies -- 15. Monitoring of Human Exposure to Xenobiotics Identification
and Quantification of Cancer Initiators in Vivo -- 16. The Role of Mass Spectrometry in Biomonitoring Exposure to Carcinogens -- 17. Characterization of Ceramide Mixtures by Fast Atom Bombardment and Tandem Mass Spectrometry -- 18.
Bioorganic Studies of a New Photoreceptor Structure -- IV: Coupling of Chromatography to Mass Spectrometry -- 19. Gas Chromatography and Mass Spectrometry Coupling -- 20. Recent Developments in Combined Supercritical Fluid
Chromatography/Mass Spectrometry (SFC/MS) -- 21. GC-MS Analysis of Volatile Compounds of Mesir -- 22. The Application of Mass Spectrometry to Food and Nutrition Research
ISBN:9789400902176
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:NATO ASI Series, Series C: Mathematical and Physical Sciences: 475
Keywords: Chemistry , Analytical chemistry , Biochemistry , Ecotoxicology , Chemistry , Analytical Chemistry , Biochemistry, general , Ecotoxicology
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Call number:SPRINGER-1996-9781475756548:ONLINE Show nearby items on shelf
Title:Lifetime Data: Models in Reliability and Survival Analysis
Author(s):
Date:1996
Size:1 online resource (410 p.)
Note:10.1007/978-1-4757-5654-8
Contents:On the Entropies and Mutual Information of Some Bivariate Continuous Distributions Used in Reliability -- Initial Conditions Problem in Event History Analysis: An Indirect Inference Procedure -- Analysis of Survival Data Under
Competing Risks with Missing Cause of Death Information: Application and Implications for Study Design -- Conditional Proportional Hazards Models -- A Comparison of Conditional and Unconditional Inference Relating to Log-Gamma
Distribution -- Universal Formulas for Treatment Effects from Noncompliance Data -- Foundational Issues Concerning the Analysis of Censored Data -- Burn-in at the Component and System Level -- Identification of Dependent Competing
Risks Models -- Reliability Modelling for Optical Amplified Communication Systems -- A Parametric Approach to Measurement Errors in Receiver Operating Characteristic Studies -- A Modification of Goel-Okumoto Model -- Models for
Degradation Processes and Event Times Based on Gaussian Processes -- A Non-Parametric Two-Sample Survival Test Based on a Single Occupancy Fermi-Dirac Model for the Discrete Range Distribution -- Probability Approximations and
Inequalities for Sequential Tests -- Cure Mixture Models in Breast Cancer Survival Studies -- A General Approach to Derive Chi-Square Type of Goodness-of-Fit Tests for Lifetime Data -- Prediction in Survival Analysis: Model or Medic --
Dynamic Reliability Models -- Generalizations of Current Status Data with Applications -- Trend Analysis of Multiple Counting Processes -- Historical Controls and Model Survival Analysis -- A Random Effects Model for Multivariate Life
Data -- Statistical Challenges in Comparing Chemotherapy and Bone Marrow Transplantation as a Treatment for Leukimia -- Maximum Likelihood Estimation and the Multivariate Bernoulli Distribution: An Application to Reliability --
Intermediate Clinical Events, Surrogate Markers and Survival -- A Semiparametric Bootstrap for Proportional Hazards Models -- Application of Cox Regression with a Change Point in Clinical Studies -- Burn-in with Age Replacement --
Fitting Cox’s Prportional Hazards Model Using Grouped Survival Data -- Statistical Methods for Dependent Competing Risks -- Orthogonal Functions of Inverse Gaussian Distributions -- Statistical Models for Quality of Life Measures --
Nonparametric Estimation of Regression Parameters from Censored Data with Two Discrete Covariates -- Locally Efficient Median Regression with Random Censoring and Surrogate Markers -- Survival Models for Heterogeneity Using the
Non-Central Chi-Squared Distribution with Zero Degrees of Freedom -- Efficiently Weighted Estimating Equations with Application to Proportional Excess Hazards -- Sequential Multi-Hypothesis Testing in Software Reliability -- Assessing
Gamma Frailty Models for Clustered Failure Time Data -- The Shapes of a Probability Density Function and its Hazard Function -- Therapeutic Equivalence Using a Rich Family of Prior Distributions -- Dependent Competing Risks with
Time-Dependent Covariates -- Life Estimation from Pooled Discrete Renewal Counts -- Efficient and Ad Hoc Estimation in the Bivariate Censonring Model -- Efficient Estimation in a Nonproportional Hazards Model -- Modeling Frailty in
Manufacturing Processes -- Estimation of Wiener Diffusion Parameters Using Process Measurements Subject to Error -- Adaptive Replacement Policies for a System of Parallel Machines -- Discrete First Passage Time Distribution for
Describing Inequality among Individuals -- A Graphical Classification of Survival Distributions -- Survival Analysis in S-Plus -- A Note on Strong Uniform Consistency of Kernel Estimators of Hazard Functions Under Random Censorship --
Identifiability and Estimation of Marginal Survival Functions for Dependent Competing Risks Assuming the Copula is Known -- Author Index
ISBN:9781475756548
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Mathematics , Cancer research , Public health , Epidemiology , Mathematical models , Probabilities , Statistics , Mathematics , Probability Theory and Stochastic Processes , Mathematical Modeling and Industrial Mathematics , Statistics, general , Public Health , Cancer Research , Epidemiology
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Call number:SPRINGER-1996-9781461311836:ONLINE Show nearby items on shelf
Title:Regulation of the RAS Signaling Network
Author(s): Hiroshi Maruta
Date:1996
Size:1 online resource (202 p.)
Note:10.1007/978-1-4613-1183-6
Contents:1. Genetics of RAS Signaling in Drosophila -- I. Introduction -- II. Background to the Experimental Systems -- III. Protein Tyrosine Kinase Receptors -- IV. Linking RAS with Tyrosine Kinase Receptors -- V. A Kinase Cascade Downstream
of RAS -- VI. Nuclear Events -- VII. Concluding Remarks -- 2. RAS-Mediated Signal Transduction in C. elegans -- I. Introduction -- II. Genetic Approaches Used to Study Vulval Signal Transduction -- III. Genetic and Molecular Analysis
of the let-60 RAS Gene -- IV. Genes Acting Upstream of RAS -- V. Genes Acting Downstream of RAS -- VI. Multiple Functions of the let-60 RAS-mediated Signal Transduction Pathway During C elegans Development -- 3. Mammals I: Regulation
of RAS Activation -- I. Introduction -- II. Growth Factor/Cytokine Signaling -- III. Growth Factor Cascades: Autocrine Stimulation -- 4. Prenylation of RAS and Inhibitors of Prenyltransferases -- I. Introduction -- II. C-Terminal
Modification of RAS Proteins -- III. Farnesyltransferase and Geranylgeranyltransferases -- IV. Mutational Analyses of Prenyltransferases -- V. Inhibitors of Prenylation -- VI. Biological Effects of Prenyltransferase Inhibitors -- 5.
Mammals II: Downstream of RAS and Actin-Cytoskeleton -- I. RAS GAPs -- II. Oncogenic Mutations of RAS -- III. Effectors of RAS -- IV. Actin-Cytoskeleton -- V. G Proteins in the Rho Family (Rho, Rac and CDC42) -- VI. RAS-Activated or
-Repressed Genes -- 6. From RAS to MAPK: Cell-Free Assay System for RAS- and Rap 1-Dependent B-Raf Activation -- I. Introduction -- II. Cell-free Assay System for the RAS-dependent Activation of the MAP Kinase Cascade in Xenopus Oocyte
Cytosol -- III. REKS -- IV. Raf Activation -- V. Conclusion
ISBN:9781461311836
Series:eBooks
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Keywords: Life sciences , Cancer research , Cell biology , Life Sciences , Cell Biology , Cancer Research
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Call number:SPRINGER-1993-9789401119740:ONLINE Show nearby items on shelf
Title:Recent Experimental and Computational Advances in Molecular Spectroscopy
Author(s):
Date:1993
Size:1 online resource (454 p.)
Note:10.1007/978-94-011-1974-0
Contents:Content -- Protonation of simple unsaturated organic compounds in their electronic ground and low lying excited states -- Application of the CI-singles method in predicting the energy, propertie and reactivity of molecules in their
excited states -- Molecular sructure from rotational and vibrational transitions in electronic spectra -- From qualitative to quantitative analyses of circular dichroism spectra using the convex constraint algorithm -- Potential energy
surfaces and vibrational anharmonicity -- Development of an ab initio based database of vibrational force fields for organic molecules -- Computer-aided methods for the resolution enhancement of spectral data with special emphasis on
infrared spectra -- Raman spectroscopy: a survey on selected topics -- ?,ß-unsaturated carboxylic esters and their hydrogen bond complexes with substituted phenols: vibrational spectra-structure correlations -- Solvent effect on
vibrational frequencies of substituted acetaldehydes -- Experimental and ab initio quantum mechanical studies of the vibrational spectra of isolated pyrimidine bases -- Pressure-tuning vibrational spectroscopy: applications from basic
molecular spectroscopy to human cancer research -- Vibrational spectroscopy of polyconjugated materials with electrical and non linear optical properties -- Surface molecular spectroscopy -- Neutron molecular spectroscopy -- Recent
advances in gas electron diffraction and structural studies by join quantum mechanical and experimental procedures -- Principles of multidimensional high-resolution NMR -- NMR structural techniques in biochemical and bioinorganic
systems: paramagnetic shift and relaxation probes -- The physics of an atom in a molecule -- Frontier orbital theory and chemical reactivity: the utility of spectroscopy and molecular orbital calculations -- Semiempirical molecular
orbital theory: facts, myths and legends -- The consistent force field: development of potential energy functions for conformational analysis -- Experimental and computational projects on molecular spectroscopy -- Short contributions:
titles and authors -- Author index
ISBN:9789401119740
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:NATO ASI Series, Series C: Mathematical and Physical Sciences: 406
Keywords: Chemistry , Chemoinformatics , Physical chemistry , Chemistry, Physical and theoretical , Atoms , Physics , Chemistry , Physical Chemistry , Theoretical and Computational Chemistry , Atomic, Molecular, Optical and Plasma Physics , Computer Applications in Chemistry
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Call number:SPRINGER-1993-9781461393320:ONLINE Show nearby items on shelf
Title:Forecasting the Health of Elderly Populations
Author(s):
Date:1993
Size:1 online resource (371 p.)
Note:10.1007/978-1-4613-9332-0
Contents:One. Introduction -- 1 The Scientific and Policy Needs for Improved Health Forecasting Models for Elderly Populations -- Two. Methodological Issues -- 2 Actuarial and Demographic Forecasting Methods -- 3 Demographic Change in the
United States, 1970–2050 -- 4 Health Forecasting and Models of Aging -- Three. Forecasting Techniques for Specific Diseases -- 5 Cancer Forecasting: Cohort Models of Disease Progression and Mortality -- 6 The Effects of Risk Factors on
Male and Female Cardiovascular Risks in Middle and Late Age -- 7 Frailty and Forecasts of Active Life Expectancy in the United States -- 8 Risk Factors Affecting Multiple-Disease Efficacy and Effectiveness of Intervention Programs --
Four. Effects of Interventions on Health Costs -- 9 Estimates and Projections of Dementia-Related Service Expenditures -- 10 A Forecasting Model for the Assessment of Medical Technologies: End-Stage Renal Disease -- 11 Projections of
the Aged Supplementary Security Income Population: The Implications of Uncertainty -- 12 Evaluation of Long-Term Care: Estimation of Health Transitions in Frail Populations -- 13 Financing and Use of Long-Term Care for the Elderly --
Five. Longitudinal Research: Current Status and Future Outlook -- 14 Molecular Biological Approaches to Understanding Aging and Senescence -- 15 Biomedical Research and Changing Concepts of Disease and Aging: Implications for Long-Term
Health Forecasts for Elderly Populations
ISBN:9781461393320
Series:eBooks
Series:SpringerLink (Online service)
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Keywords: Mathematics , Probabilities , Statistics , Mathematics , Probability Theory and Stochastic Processes , Statistics for Life Sciences, Medicine, Health Sciences
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Call number:SPRINGER-1990-9789400919365:ONLINE Show nearby items on shelf
Title:Activation of Hormone and Growth Factor Receptors Molecular Mechanisms and Consequences
Author(s):
Date:1990
Size:1 online resource (320 p.)
Note:10.1007/978-94-009-1936-5
Contents:Activation of Hormone and Growth Factor Receptors: Molecular Mechanisms and Consequences: A record of the Meeting -- Signal Transduction and Control of Cell Proliferation and Differentiation -- Insulin Receptor and Insulin Action --
Signal Transduction by Growth Factor Receptors -- Cholera Toxin: Transport and Structural Basis of Action -- Analysis and Transfection of Human Acidic Fibroblast Growth Factor (aFGF) cDNA Clones and Structural Analysis of the Human
aFGF Gene reveals Features Shared within a Family of Homologous Proteins -- Growth Factor Synthesis by a Human Teratocarcinoma cell line: Implications for Autocrine Growth in the Human Embryo? -- The Role of Oncogene Activation -- The
Role of Ras P21 Product in Cell Transformation -- DNA Binding Properties of the Thyroid Hormone Receptor/c-erbA Protein and its Viral Homologue P75 gag-v-erbA -- The Role of Fos in Gene Regulation -- 6-Phosphofructo-2-Kinase links
Glycolysis to Mitogenic Agents and has Sequence Similarity with Proteins encoded by Oncogenic DNA Viruses -- Steroid Receptors and Transcriptional Control -- The Regulation of RNA Polymerase II Activity by Multisite Phosphorylation --
Transcription Factors of RNA Polymerase III from Mammalian Cells -- Steroid response elements: Composite Structure and Definition of a Minimal Element -- Gene Regulation by Steroid Hormones -- Regulation of Liver Gene Expression in
Dexamethasone Resistant Hepatoma Cells -- The Kinetics of Oestrogen-induced Gene Expression in the Immature Rat Uterus -- Structure and Function of Steroid Receptors -- Functional Domains of Steroid Hormone Receptors -- Genetic and
Biochemical Analysis of a Steroid Receptor -- Analysis of Subunit Interactions in Steroid Receptors using Chemical Cross-Linking -- Possible Functional Interaction between Steroid Hormone Receptors and Heat Shock Protein Mr 90.000 (hsp
90) -- Mechanism of Action of Estrogens: Phosphorylation of Estradiol Receptor on Tyrosine -- Glucocorticoid Receptor and Hormonal Extragenomic Effects -- Clinical Implications of Steroid Receptor Research -- Estrogen Receptors in
Mouse Mammary Tumors -- Structure of Glucocorticoid Receptor in Cancer Tissues
ISBN:9789400919365
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:NATO ASI Series, Series C: Mathematical and Physical Sciences: 295
Keywords: Life sciences , Biochemistry , Zoology , Animal anatomy , Animal physiology , Life Sciences , Zoology , Animal Anatomy / Morphology / Histology , Animal Physiology , Biochemistry, general
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Call number:SPRINGER-1990-9781468458503:ONLINE Show nearby items on shelf
Title:Genetic Toxicology of Complex Mixtures
Author(s):
Date:1990
Size:1 online resource (384 p.)
Note:10.1007/978-1-4684-5850-3
Contents:Development and Application of New Methodologies Applicable to Research on Complex Environmental Mixtures -- Complex Mixtures of Genotoxicants in Air -- Identification of Genotoxic Agents in Complex Mixtures of Air Pollutants -- Human
Exposure to Airborne Mutagens Indoors and Outdoors Using Mutagenesis and Chemical Analysis Methods -- Genetic Toxicology of Airborne Particulate Matter Using Cytogenetic Assays and Microbial Mutagenicity Assays -- Indoor and Outdoor
Sources of Airborne Mutagens in Nonurban Areas -- Characterization of Mutagen Sources in Urban Particulate Matter in Gothenburg, Sweden -- Assessment of the Mutagenicity of Volatile Organic Air Pollutants Before and After Atmospheric
Transformation -- Carcinogenicity of Complex Mixtures in Air Using In Vitro and In Vivo Assays -- Contribution of Polycyclic Aromatic Hydrocarbons and Other Polycyclic Aromatic Compounds to the Carcinogenicity of Combustion Sources and
Air Pollution -- Old and New Carcinogens -- Experimental and Epidemiologic Applications to Cancer Risk Assessment of Complex Mixtures -- Mutagenicity, Carcinogenicity, and Human Cancer Risk from Indoor Exposure to Coal and Wood
Combustion in Xuan Wei, China -- The Role of Nitroarenes in the Mutagenicity of Airborne Particles Indoors and Outdoors -- Complex Mixtures of Genotoxicants in Waters -- Characterization of Mutagenic Compounds Formed During
Disinfection of Drinking Water -- Genotoxic and Carcinogenic Properties of Chlorinated Furanones: Important By-products of Water Chlorination -- Assessment and Identification of Genotoxic Compounds in Water -- Methods to Measure
Genotoxins in Wastewater: Evaluation with In Vivo and In Vitro Tests -- Detection of Genotoxicity in Chlorinated or Ozonated Drinking Water Using an Amphibian Micronucleus Test -- Exposure/Effects Assessment -- The Significance of
Mutagenicity as a Criterion in Ecotoxicological Evaluations -- DNA Adducts and Related Biomarkers in Assessing the Risk of Complex Mixtures -- Immunological Methods for the Detection of Polycyclic Aromatic Hydrocarbon-DNA and Protein
Adducts -- 32P-Postlabeling DNA Adduct Assay: Cigarette Smoke-induced DNA Adducts in the Respiratory and Nonrespiratory Rat Tissues -- Postlabeling Analysis of Polycyclic Aromatic Hydrocarbon: DNA Adducts in White Blood Cells of
Foundry Workers -- Protein Adducts as Biomarkers for Chemical Carcinogens -- Evaluation of DNA Binding In Vivo for Low-Dose Extrapolation in Chemical Carcinogenesis -- Cancer Risks Due to Occupational Exposure to Polycyclic Aromatic
Hydrocarbons: A Preliminary Report -- Future Directions in Research on the Genetic Toxicology of Complex Mixtures
ISBN:9781468458503
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:Environmental Science Research : 39
Keywords: Medicine , Human genetics , Pharmacology , Ecotoxicology , Waste management , Biomedicine , Pharmacology/Toxicology , Human Genetics , Waste Management/Waste Technology , Ecotoxicology
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Call number:SPRINGER-1985-9781461250982:ONLINE Show nearby items on shelf
Title:Data A Collection of Problems from Many Fields for the Student and Research Worker
Author(s): D. F Andrews
Date:1985
Size:1 online resource (442 p.)
Note:10.1007/978-1-4612-5098-2
Contents:1. Iris Data -- 2. Darwin’s Data on Growth Rates of Plants -- 3. Canadian Lynx Trappings -- 4. The Number of Deaths by Horsekicks in the Prussian Army -- 5. The Yields of Wheat on the Broadbalk Fields at Rothamsted -- 6. Uniformity
Trials: Variation and Correlationin the Yield of Wheat -- 7. Stanford Heart Transplant Data -- 8. Coal-Mining Disasters -- 9. Recoiling of Guns -- 10. Old Maps -- 11. Monthly Mean Sunspot Numbers -- 12. Ozone Column -- 13. Downwind
Effects from the Arizona Cloud Seeding Experiments -- 14. Half Hourly Precipitation and Streamflow, River Hirnant, Wales, U.K., November and December, 1972 -- 15. The Rainfall at Adelaide, South Australia -- 16. Particle Size
Distribution of Soil Profiles -- 17. Identifying Groundwater Populations -- 18. Soil Data from the Province of Murcia, Spain -- 19. Lamoka Lake Site Determinations -- 20. Variations in the Earth’s Rotation Rate, 1820–1970 -- 21.
Association of Pairs of Radio Sources with Peculiar Galaxies -- 22. Motions of Stars in a Star Cluster, M92 -- 23. Motions and Distances of Planetary Nebulae -- 24. Quality Control Data in Clinical Chemistry -- 25. Calcium Assay -- 26.
Determination of Dunham Coefficients for the Ground State of D2 -- 27. Clock Intercomparisons -- 28. An Evaluation of Cryogenic Flow Meters -- 29. Stress-Rupture Life of Kevlar 49/Epoxy Spherical Pressure Vessels -- 30. A Chemical
Reaction -- 31. Product Preferences -- 32. Incidence of Malignant Melanoma After Peaks of Sunspot Activity -- 33. Supplemental Ascorbate, Vitamin C, in the Supportive Treatment of Cancer -- 34. Incidence of Byssinosis: A
Cross-Sectional Occupational Health Study -- 35. Inter and Intra Individual Variation of Blood Glucose Levels -- 36. Chemical and Overt Diabetes -- 37. The Maternal Age Distribution of Patients with Down’s Syndrome -- 38. Procedures
for the Detection of Muscular Dystrophy Carriers -- 39. Lengths of Remissions for Children with Acute Leukemia -- 40. Testis Tumours in Japan -- 41. Consecutive Measurements of Plasma Citrate Concentrations -- 42. Time to Death and
Type of Death in Mice Receiving Various Doses of Red Dye No. 40 -- 43. Cariogenic Effects of Diet -- 44. Physical Characteristics of Urines With and Without Crystals -- 45. Multiple Tumour Recurrence Data for Patients with Bladder
Cancer -- 46. Prognostic Variables for Survival in a Randomized Comparison of Treatments for Prostatic Cancer -- 47. Visual Pattern Recognition -- 48. Circadian Rhythms -- 49. Number of Species in the Galápagos Islands -- 50. The
Spatio-Temporal Spread of Fox Rabies -- 51. Measuring the Avoidance of Super-Parasitism: Are Balls Scattered Non-Randomly into Boxes? -- 52. Effect of Chemicals on Earthworm Populations -- 53. The Classification of Three Historical
Specimens of Grey Kangaroos -- 54. Social Grooming in North American River Otters -- 55. Species Composition in a Complex of Woodlands -- 56. Distribution Patterns of Plant Species -- 57. The Garrison Bay Project, Stock Assessment and
Dynamics of the Littleneck Clam, Protothaca staminea -- 58. Maize Fertilizer Experiments on the Islands of St. Vincent and Antigua -- 59. Disorder and Mineral Content in Apples -- 60. A Classical Apple Experiment -- 61. Mastitis
Control by Penicillin and Novobiocin -- 62. United Kingdom Pig Production 1967–1978 -- 63. Comparison of Family Sizes: A Problem from the 1941 Canadian Census -- 64. Canadian Unemployment Data 1956–1975 -- 65. United States of America
Unemployment Data, 1948–1981 -- 66. Interorganizational Resource Links in Towertown, U.S.A. -- 67. Insurance Availability in Chicago -- 68. Factors Influencing Motor Insurance Rates -- 69. Disputed Authorship: The Federalist Papers --
70. Platonic Prose Rhythm -- 71. Relationships between Birthday and Deathday
ISBN:9781461250982
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Statistics , Statistics , Statistics, general
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Call number:SPRINGER-1984-9781461328032:ONLINE Show nearby items on shelf
Title:Stress and Tension Control 2
Author(s):
Date:1984
Size:1 online resource (420p p.)
Note:10.1007/978-1-4613-2803-2
Contents:Foreword -- An Overview of Contemporary Work in the Field of Stress and Tension Control -- Edmund Jacobson, Father of the Field of Relaxation -- Tension Control for Coping and for Habit Change -- On Edmund Jacobson’s Way of Life -- On
the Professional Accomplishments of Edmund Jacobson -- Research Strategies and Approaches -- Stress and Personality as Contributory Factors in the Causation of Cancer -- Research on Stress Ought to be Revised -- Some Clinical
Observations on Muscle Tension and Expressive Movement -- Discrimination of Visceral Stimuli, Biofeedback and Self-Regulation: A Methodological Proposal -- A Model of People at High Risk to Develop Chronic Stress Related Symptoms --
Social Psychophysiology of Relaxation Training -- The Role of Substance P in Normalizing Stress Response -- Clinical Applications in Medicine, Psychology-Psychiatry, Speech Pathology and Dentistry -- Stress, Tension and Rheumatic
Disease -- Neuromuscular Psychophysiology of Depression -- “Stress Headaches” from Causes in the Musculoskeletal System and their Treatment by Physical Means -- Biofeedback Treatment of Primary Raynaud’s -- Biofeedback: Treatment of
Essential Hypertension -- Behavioural Style, Myocardial Infarction, and Cardiovascular Responsiveness -- Tension Control in Speech Pathology -- Self-Help Groups for Agoraphobics: Their Role in Coping with Anxiety and Depression -- The
Perception by Dentists and Patients of Fear in Dental Treatment -- Studies of Stress and Tension in Occupational Settings -- Occupational Stress Testing in the Real World -- Stress at Work: A Review of Australian Research -- Autogenic
Training as a Stress Management Tool in Air Transport Operations -- The Effect of Autogenic Training upon the Flying Skill of Pilots Under Stress -- Reduction of Stress by Personnel at Institutions for Child Care and for the Mentally
Handicapped -- Stress and Tension Control in Education -- An Experimental Study of Relaxation Training in Swedish Schools: Psychological and Physiological Results -- Some Uses and Limitations of Stress Control Methods in a Local
Authority Educational Psychology Service -- Improved Stress Management and Tension Control: A Model Program in a Community College -- Worksite Stressors and University Faculty -- Teaching Dynamic Relaxation at the University of the
Third Age — Paris VI -- Methods of Coping with Stress -- Cognitive Strategies to Reduce Stress in Competitive Athletic Performance -- Physical Activity and Stress Reduction: A Review of Selected Literature -- The Physical Mirror of
Stress -- The Mitchell Method of Physiological Relaxation
ISBN:9781461328032
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Physics , Mechanics , Physics , Mechanics
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Call number:SPRINGER-1984-9781461323990:ONLINE Show nearby items on shelf
Title:Mutation, Cancer, and Malformation
Author(s):
Date:1984
Size:1 online resource (855p p.)
Note:10.1007/978-1-4613-2399-0
Contents:Genetic Factors in Human Diseases -- Environmental mutagenesis and disease in human populations -- Clinical genetics of human cancer -- Chromosome abnormalities in cancer development -- Mutations of cellular oncogenes as a basis for
neoplastic change -- Human gene mapping in the analysis of oncogenes -- Basic Concepts in Mutagenesis and Carcinogenesis -- Relationship between mutagenesis and carcinogenesis -- Theoretical basis of mutagenesis -- DNA repair processes
-- The Role of DNA repair in mutation induction -- Use of the Bacilussubtilus Rec-assay in environmental mutagen studies -- Mutagenesis in yeasts -- A comparison of genotoxic activity in somatic tissue and in the germ cells of
Drosophilamelanogaster -- The P-factor: a transposable element in Drosophila -- Silkworm genetics and chemical mutagenesis -- Mutation induction and detection in Arabidopsis -- Mutagenesis studies with cultured mammalian cells:
problems and prospects -- The control of cell transformation, mutagenesis and differentiation by chemicals that initiate or promote tumor formation -- Dominant-lethal mutations and heritable translocations in mice -- Recessive and
dominant mutations in mice -- Benzo (a)pyrene and 6-nitrobenzo (a) pyrene metabolism in human and rodent microsomes and tissue culture -- Nitrosamine metabolism and carcinogenesis -- Modification of carcinogenesis by dietary and
nutritional factors -- Naturally occurring mutagens -- Reproductive Toxicology -- Teratogenesis -- A possible mechanistic link between teratogenesis and carcinogenesis: inhibited intercellular communication -- Gem cell toxicity:
significance in genetic and fertility effects of radiation and chemicals -- Environmental Toxicology, Mutagenesis, and Carcinogenesis -- The science of toxicology — scope, goals and four case studies -- Mutagenicity of pesticides --
Genetic toxicology of 14 agents casually associated with cancer in humans -- Sensitivity, specificity and accuracy of the Arabidopsis assay in the identification of carcinogens -- Environmental studies in Sweden -- Research progress on
environmental mutagenesis, carcinogenesis and teratogenesis in China -- A. Strategy of approach to cancer control in China -- Toxicological research in public health: the Chinese experience -- Environmental mutagenesis research at
Fudan University -- The role of risk assessment in regulatory decisions in the United States -- Alternate methods for integrated evaluation of toxicity and risk assessment -- Posters
ISBN:9781461323990
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:Environmental Science Research : 31
Keywords: Physics , Physics , Physics, general
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Call number:SPRINGER-1983-9781461337904:ONLINE Show nearby items on shelf
Title:Application of Biological Markers to Carcinogen Testing
Author(s):
Date:1983
Size:1 online resource (516p p.)
Note:10.1007/978-1-4613-3790-4
Contents:Welcoming Remarks -- An Overview of Current Research Efforts on the Application of Biological Markers to Carcinogen Testing -- In Vivo Tests -- Chairman’s Overview on In Vivo Tests -- The Occurrence of Neoplasms in Long-Term In Vivo
Studies -- Markers of Liver Neoplasia — Real or Fictional? -- Early Morphologic Markers of Carcinogenicity in Rat Pancreas -- Rodent and Human Models for the Analysis of Intestinal Tumor Development -- Effect of Diet on Intestinal
Tumor Production -- Tumor Antigens as Markers for Carcinogens -- In Vitro Tests -- Chairmen’s Overview on In Vitro Tests -- Biochemistry and Biology of 2-Acetyl-Aminofluorene in Primary Cultures of Adult Rat Hepatocytes -- Relating In
Vitro Assays of Carcinogen-Induced Genotoxicity to Transformation of Diploid Human Fibroblasts -- Evaluation of Chronic Rodent Bioassays and Ames Assay Tests as Accurate Models for Predicting Human Carcinogens -- Indices for
Identification of Genotoxic and Epigenetic Carcinogens in Cell Culture -- Enzymes -- Chairmen’s Overview on Enzyme Markers -- Aryl Hydrocarbon Hydroxylase Activity “of Mice and Humans” -- Gamma-Glutamyl Transpeptidase Expression in
Neoplasia and Development -- Ornithine Decarboxylase: Alterations in Carcinogenesis -- Human Tumors: Enzyme Activities and Isozyme Profiles -- Enzyme and Isoenzyme Patterns as Potential Markers of Neoplasia in Breast Tissue --
Oncofetal Antigens and Hormones -- Chairmen’s Overview on Oncodevelopmental Markers -- Alphafetoprotein as a Marker for Early Events and Carcinoma Development During Chemical Hepatocarcinogenesis -- Human Chorionic Gonadotropin and its
Subunits as Tumor Markers -- Prostaglandins and Cancer -- Monoclonal Antibodies -- Chairmen’s Overview on the Use of Immunoanalytical Method for the Characterization and Quantification of DNA Components Structurally Modified by
Carcinogens and Mutagens -- Immunological Approaches for the Detection of DNA Modified by Environmental Agents -- Detection of Thymine Dimers in DNA with Monoclonal Antibodies -- Immunological Studies on the Influence of Chromatin
Structure on the Binding of a Chemical Carcinogen to the Genome -- High-Affinity Monoclonal Antibodies Specifically Directed Against DNA Components Structurally Modified by Alkylating N-Nitroso Compounds -- Carcinogen-Induced
Modification in DNA -- Chairmen’s Overview on Carcinogen-Induced Modification in DNA -- Use of Repair-Deficient Mammalian Cells for the Identification of Carcinogens -- Thymine Modifications in DNA as Markers of Radiation Exposure --
Aberrant Methylation of DNA as an Effect of Cytotoxic Agents -- Identification of Carcinogen-DNA Adducts by Immunoassays -- Viruses -- Chairman’s Overview on Integration and Expression of the Polyoma Virus Oncogenes in Transformed
Cells -- Activation of Cellular onc (c-onc) Genes: A Common Pathway for Oncogenesis -- Hepatitis B Virus as an Environmental Carcinogen -- Roundtable Discussion -- Research Needs on the Use of Tumor Markers in the Identification of
Chemical Carcinogens -- Posters -- The Polypeptides of the Cytosol of Hepatocyte Nodules May Exhibit a Unique Electrophoretic Pattern -- Rat Alloantigens as Cellular Markers for Hepatocytes in Genotypic Mosaic Livers During Chemically
Induced Hepatocarcinogenesis -- Metabolic Considerations in the Toxicity and Mutagenicity of the Nitronaphthalenes -- Detection and Identification of Common Oncofetal Antigens on In Vitro Transformed Mouse Fibroblasts -- Inhibition of
Metabolic Cooperation Between Cultured Mammalian Cells by Selected Tumor Promoters, Chemical Carcinogens, and Other Compounds -- A Rapid In Vitro Assay for Detecting Phorbol Ester-like Tumor Promoters -- Induction of Endogenous Murine
Retrovirus by Chemical Carcinogens -- In Utero Induction of Sister Chromatid Exchanges to Detect Transplacental Carcinogens -- Evaluation of Known Genotoxic Agents and ?9 -Tetrahydrocannabinol for SCE Induction by the Intraperitoneal
5-Bromo-2’-Deoxyuridine Infusion Technique for Sister Chromatid Exchange Visualization -- Effect of 2,3-Oxide-3,3,3-Trichloropropane on BaP Metabolism in Mullet -- The Effect of Dimethylbenzanthracene on the NK Activity of Mice
ISBN:9781461337904
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:Environmental Science Research : 29
Keywords: Physics , Physics , Physics, general
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Call number:SPRINGER-1981-9783642464416:ONLINE Show nearby items on shelf
Title:Optimization of Human Cancer Radiotherapy
Author(s): George W Swan
Date:1981
Size:1 online resource (284 p.)
Note:10.1007/978-3-642-46441-6
Contents:1 General Introduction -- 1.1 Introduction -- 1.2 History of Cancer and its Treatment by Radiotherapy -- 1.3 Some Mathematical Models of Tumor Growth -- 1.4 Spatial Distribution of the Radiation Dose -- 2 Survival Curves from
Statistical Models -- 2.1 Introduction -- 2.2 The Target Model -- 2.3 Single-hit-to-kill Model -- 2.4 Multitarget, Single-hit Survival -- 2.5 Multitarget, Multihit Survival -- 2.6 Single-target, Multihit Survival -- 2.7 Properties of
In Vitro Survival Curves -- 3 A Molecular Model of cell Survival -- 3.1 Introduction -- 3.2 The Molecular Model -- 3.3 Interpretations of the Molecular Model -- 4 Kinetic Models of Biological Radiation Response -- 4.1 Introduction --
4.2 Basic Postulates in the Dienes Model -- 4.3 Low LET Kinetic Models with no Recovery -- 4.4 Further Discussion of the Models -- 4.5 Low LET Kinetic Models with Recovery -- 4.6 Low LET and High LET Kinetic Model with No Recovery --
4.7 Other Kinetic Schemes: Sparsely-ionizing Radiation -- 4.8 Kinetic Schemes with Age-specific Compartments in the Cell Cycle -- 4.9 Thermal Potentiation of Cell Killing -- 5 Cell Survival after Successive Radiation Fractions -- 5.1
Introduction -- 5.2 Some Results in Connection with Instantaneous Cell Kill and Exponential Tumor Growth -- 5.3 Instantaneous Cell Kill Followed by Logistic Growth of Normal Tissue -- 5.4 Cohen’s Cell Population Kinetics Programs --
5.5 A Model of Radiation Therapy with Resistant and Sensitive Cell Populations -- 5.6 Dose Fractionation and General Survival Curves -- 6 Optimization Models in Solid Tumor Radiotherapy -- 6.1 Introduction -- 6.2 Optimal Radiotherapy
of Tumor Cells Based on Cumulative Radiation Effect and a Multitarget, Single-hit Survival Function -- 6.3 Optimal Radiotherapy of Tumor Cells Based on Cumulative Radiation Effect and an Exponential-quadratic Survival Expression -- 6.4
Fractionation Scheme with a Four Level Population Tumor Model -- 6.5 A Dynamic Programming Solution to the Problem of the Determination of Optimal Treatment Schedules -- 6.6 Optimal Treatment Schedules in Fractionated Radiation Therapy
for Fischer’s Tumor Model -- 6.7 Optimal Radiation Schedules with Cell Cycle Analysis -- 7 Numerical Solution of Multistage Optimal Control Problems -- 7.1 Introduction -- 7.2 Continuous Time Optimal Control -- 7.3 Optimization of
Multistage Systems -- 7.4 Multi-dimensional Optimization by Gradient Methods -- 7.5 Gradient Method with Penalty Function -- 7.6 A Numerical Scheme for a Nonlinear Problem -- 7.7 The Method of Conjugate Gradients -- 7.8 Discrete
Dynamic Programming -- 8 Some Optimization Criteria in Radiotherapy -- 8.1 Introduction -- 8.2 Therapeutic Policy, Strategy and Tactics -- 8.3 Optimization and Clinical Trials -- 8.4 Score Functions and Age Response Functions -- 8.5
Comparison of Models Used in Optimization Procedures -- 8.6 The Complication Probability Factor -- 9 The Optimization of External Beam Radiation Therapy -- 9.1 Introduction -- 9.2 Some Approaches for Treatment Plans -- 9.3 Linear
Programming -- 9.4 Linear Programming and Radiation Treatment Planning -- 9.5 Optimization of External Beam Radiation Therapy Using Nonlinear Programming -- 9.6 Quantitative Study of Relative Radiation Effects and Isoeffect Patterns --
10 Reconstructive Tomography -- 10.1 Introduction -- 10.2 Reconstruction Algorithm -- 10.3 Numerical Approximations for the Attenuation Coefficient -- 10.4 Cross-sectional Absorption Density Reconstruction for Treatment Planning --
10.5 Towards the Optimization of Dose Reduction in Computerized Tomography -- 10.6 Other Imaging Technologies -- Appendix 1 -- Appendix 2 -- Appendix 3
ISBN:9783642464416
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:Lecture Notes in Biomathematics: 42
Keywords: Medicine , Cancer research , Oncology , Biomathematics , Medicine & Public Health , Oncology , Mathematical and Computational Biology , Cancer Research
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Call number:SPRINGER-1981-9781461394648:ONLINE Show nearby items on shelf
Title:Computer Science and Statistics: Proceedings of the 13th Symposium on the Interface
Author(s):
Date:1981
Size:1 online resource (378 p.)
Note:10.1007/978-1-4613-9464-8
Contents:Keynote Address -- Statistical Theory and the Computer -- Automated Edit and Imputation -- Developing an Edit System for Industry Statistics -- Design of Experiments to Investigate Joint Distributions in Microanalytic Simulations --
Descriptive Statistics Used in Monitoring Edit and Imputation Processes -- Do Statistical Packages Have a Future? -- The Effect of Personal Computers on Statistical Practice -- Statistical Software Design and Scientific Breakthrough:
Some Reflections on the Future -- Some Thoughts on Expert Software -- Fourier Transforms in Applied Statistics -- How Fast is the Fourier Transform? -- Polynomial Time Algorithms for Obtaining Permutation Distributions -- Efficient
Estimation for the Stable Laws -- Algorithms and Statistics -- Applications of Statistics to Applied Algorithm Design -- Algorithms with Random Input -- Recent Results on the Average Time Behavior of Some Algorithms in Computational
Geometry -- Genuinely Statistical Methods in the Theory of Algorithms -- Pattern Recognition -- Applications of Pattern Recognition Methods to Hydrologic Time Series -- Recent Advances in Bump Hunting -- Pattern Recognition in the
Context of an Asbestos Cancer Threshold Study -- Histologic Patterns and Random Chromatic Graphs -- Volume Testing of Statistical Programs -- Volume Testing of Statistical/Database Software -- Scientific Information Retrieval
(SIR/DBMS) -- Volume Testing of Statistical Software — The Statistical Analysis System (SAS) -- Solving Complex Database Problems in P-STAT -- Volume Testing of SPSS -- Volume Testing of Statistical Systems -- Random Number Generation
-- In Search of Correlation in Multiplicative Congruential Generators with Modulus 231 — 1 -- Portability Considerations for Random Number Generators -- Generating Discrete Random Variables in the Computer -- Generation of Random
Variables by Thinning of Poisson Processes -- Understanding Time Series Analysis -- Recent Developments in Spectrum and Harmonic Analysis -- On Some Numerical Properties of ARMA Parameter Estimation Procedures -- Time Series Recursions
and Self-Tuning Control -- Measurement and Evaluation of Software -- On Measurement and Evaluation of Software: A View from the Chair -- Can Statistical Methods Help Solve Problems in Software Measurement? -- Measuring the Performance
of Computer Software — A Dual Role for Statisticians -- Software Metrics: Paradigms and Processes -- A Proposal for Structural Models of Software Systems -- Software Metrics: A Key to Improved Software Development Management --
Orthogonalization: An Alternative to Sweep -- Orthogonalization-Triangularization Methods in Statistical Computati ons -- Research Data Base Management -- Simple Query Language Requirements for Research Data Management -- Data Editing
on Large Data Sets -- Data Archiving: A New(?) Set of Problems for Research Data Management Systems -- Graphical Methods and Their Software -- Census Bureau Statistical Graphics -- Mosaics for Contingency Tables -- The Use of Kinematic
Displays to Represent High Dimensional Data -- Contributed Papers -- Order Statistics and an Experiment in Software Design -- Further Approximation to the Distributions of Some Transformations to the Sample Correlation Coefficient --
Using Linear Programming to Find Approximate Solutions to the Fields to Impute Problem for Industry Data -- Using Computer-Binned Data for Density Estimation -- On the Nonconsistency of Maximum Likelihood Nonparametric Density
Estimators -- Computer Program for Krishnaiah’s Finite Intersection Tests for Multiple Comparisons of Mean Vectors -- Approximating the Log of the Normal Cumulative -- A Kth Nearest Neighbour Clustering Procedure -- Interactive
Statistical Graphics: Breaking Away -- Interactive Graphical Analysis for Multivariate Data -- SLANG, A Statistical Language for Descriptive Time Series Analysis -- On the Parameter Estimation in Queueing Theory -- Statistical
Computation with a Microcomputer -- On the Exact Distribution of Geary’s U-Statistic and its Application to Least Squares Regression -- Exposure to the Risk of an Accident: The Canadian Department of Transport National Driving Survey
and Data Analysis System, 1978-79 -- CONCOR: An Edit and Automatic Correction Package -- BGRAPH: A Program for Biplot Multivariate Graphics -- MONCOR--A Program to Compute Concordant and Other Monotone Correlations -- Computer
Offerings for Statistical Graphics--An Overview -- Computing Percentiles of Large Data Sets -- A Self-Describing Data File Structure for Large Data Sets -- Nonlinear Estimation Using a Microcomputer -- Statistical Procedures for Low
Dose Extrapolation of Quanta! Response Toxicity Data -- An Economic Design of Y-Charts with Warning Limits to Control Non-Normal Process Means -- Prior Probabilities, Maximal Posterior, and Minimal Field Error Localization
ISBN:9781461394648
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Mathematics , Probabilities , Statistics , Mathematics , Probability Theory and Stochastic Processes , Statistics, general
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Call number:SPRINGER-1980-9781461330301:ONLINE Show nearby items on shelf
Title:Bladder Tumors and other Topics in Urological Oncology
Author(s):
Date:1980
Size:1 online resource (528 p.)
Note:10.1007/978-1-4613-3030-1
Contents:TNM Classification of Urological Tumors — 1978 Edition -- T Category in Renal Carcinoma -- TNM Classification in Urinary Bladder Tumors: Value of Ta Category for Noninfiltrating Exophytic Tumors -- Prednimustine -- Orgotein Efficacy
in Ameliorating Side Effects Due to Radiation Therapy -- Metronidazole: A Radiosensitizer of the Hypoxic Cells -- Cis-Diammine-Dichloro-Platinum Single Drug and Combination Chemotherapy in the Treatment of Genitourinary Cancer -- The
Aims and Activities of the EORTC Urological Group -- WHO Collaborating Center for Research and Treatment of Urinary Bladder and Prostatic Carcinoma -- Chemical Carcinogenesis — A Review and Personal Observations with Special Reference
to the Role of Tobacco and Phenacetin in the Production of Urothelial Tumors -- Pathology of Bladder Tumors. The Urologist’s Point of View -- Newer Aspects of Research in the Field of Bladder Tumors -- Cytology of Bladder Tumors —
Round Table -- Scanning and Transmission Electron Microscopy of Hyperplastic and Neoplastic Human Urothelium -- In Situ Carcinoma of the Bladder -- Primary and Secondary Carcinoma-In-Situ -- Computed Tomography of Bladder Tumors --
Transrectal Ultrasonography: Staging of Bladder Tumors -- Lymphangiography in Advanced Bladder Cancer -- Clinical Significance of Urinary CEA Estimations in the Follow-Up of Patients with Bladder Carcinoma -- Glycosaminoglycans (GAG)
in the Normal and Neoplastic Urinary Bladder — Preliminary Results -- Collagenase Activity in Human Bladder Cancers -- The Copenhagen Bladder Cancer Project 1968–1971 -- Factors Influencing Prognosis in Patients with Bladder Tumors --
Urinary Tract Infection in Patients with Bladder Tumor -- Adenocarcinoma of the Bladder -- to Immunology and Immunotherapy of Bladder Tumors -- Immune Response in Bladder Cancer -- Monocyte Function in Bladder Cancer -- T and B
Lymphocytes in Patients with Bladder Tumors -- ABH-Antigenicity in T1 Urothelial Tumors -- Humoral and Cellular Immune Response in Patients with Transitional Cell Carcinoma of the Urinary Bladder (TCC) Against Bladder Carcinoma Cells
in Tissue Culture -- Immunotherapy in Bladder Cancer -- Intravesical BCG (Bacillus Calmette-Guerin) in the Management of T1 Nx Mx Transitional Cell Tumors of the Bladder: A Toxicity Study -- BCG Vaccine in the Treatment of
Noninfiltrating Papillary Tumors of the Bladder -- Transurethral Surgery -- Transurethral Resection or Cystectomy? An Attempt to Answer this Question by an Evaluation of 688 Patients with Carcinoma of the Bladder (with Special
Reference to Age, Sex, Stage, and the Presence of Associated Disease) -- Partial Cystectomy -- Autologous Human Skin Flaps in Partial Replacement of the Bladder Wall -- Indications for Cystectomy -- The Results of Total Cystectomy for
Carcinoma of the Bladder -- Radical Cystectomy in Advanced Bladder Tumors -- Cancer of the Urethra Following Cystectomy -- Supravesical Urinary Diversion -- Treatment of the Cancer of the Bladder by Irradiation, Cystoprostatectomy and
Ileocystoplasty -- A Type of Rectal Pouch for Urinary Diversion After Cystectomy -- Comparison of Bricker and Wallace Methods of Ureteroileal Anastomosis in Urinary Diversion -- Lymphadenectomy in Bladder Cancer -- Effects of
Intravesical Formaldehyde-Instillation (Experimental and Clinical Results) -- Hydrostatic Pressure Technique and Intravesical Instillation of Formalin: Methods for the Control of Severe Bleeding from the Bladder -- Intravesical
Hyperthermia for Transitional Cell Carcinoma of the Bladder -- Hyperthermia and Bladder Cancer -- Radiotherapy in the Management of Bladder Carcinoma -- Carcinoma of the Bladder Category T3 Nx, 0–4 MO Treated by Preoperative
Irradiation Followed by Cystectomy at the Rotterdam Radiotherapy Institute -- Surgical Treatment of 8l Deep Infiltrating Bladder Tumors after Preoperative Irradiation -- Cystectomy Following Full Course Irradiation -- Complications of
Irradiation of Urological Tumors -- Post-Diversion, Pre-Cystectomy Irradiation for Transitional Cell Carcinoma of the Bladder -- Treatment of Malignant Tumors of the Bladder by Iridium 192 Wiring -- Carcinoma of the Urinary Bladder
Treated by Interstitial Radium Implant -- Radioactive Source Implantation in Bladder Tumors -- Intravesical Treatment of Superficial Urinary Bladder Tumors with Adriamycin -- Intravesical Therapy with Adriamycin in Patients with
Superficial Bladder Tumors -- Local Treatment of Uroepithelial Bladder Tumors with Adriamycin -- Adriamycin Therapy in Carcinoma in Situ: A Preliminary Report -- Bladder Instillation of Adriamycin in Multiple Recurrent Non-Invasive
Papillomatous Bladder Tumors -- Survival in Patients Treated with Epodyl (1968–1978) -- Long-Term Intracavitary Epodyl® in Multiple or Extensive Papillary Tumors of the Urinary Bladder -- Treatment of Multiple Non-Invasive Bladder
Tumors with Intravesical Epodyl® -- The Treatment of Single and Multiple Papillary Tumors of the Bladder (Ta/Tl NX MO) -- Adjuvant Therapy of T1 Bladder Carcinoma: Preliminary Results of an EORTC Randomized Study -- Intravesical
Cis-Platinum in Bladder Tumors: Toxicity Study -- The Treatment of Bladder Cancer with Vitamin A -- The Veterans Administration Study of Chemo-Prophylaxis for Recurrent Stage I Bladder Tumors: Comparisons of Placebo, Pyridoxine, and
Topical Thiotepa -- Flat Carcinoma In-Situ of the Bladder Treated by Systemic Cyclophosphamide — A Preliminary Report -- Methotrexate Therapy for Multiple Tl Category Bladder Carcinoma -- The Place of Chemotherapy in the Treatment of
Patients with Invasive Carcinoma of the Bladder -- Chemotherapy in the Treatment of Invasive Bladder Cancer -- 5-Fluorouracil and Adriamycin in Locally Recurrent and/or Metastatic Bladder Cancer -- Adjuvant Chemotherapy Following
Primary Irradiation in T3 Bladder Cancer -- 5-Fluorouracil in the Treatment of Recurrent Cancer of the Urinary Bladder -- Radiotherapy, Chemotherapy and Immunotherapy for Carcinoma of the Bladder -- Integrated Therapy for Invasive
Bladder Carcinoma -- Cancer Chemotherapy, with Special Emphasis on the Role and Influence of Clinical Trials -- Oestrogen — Androgen Balance in Human Breast and Prostate Cancer -- Steroid Receptors in Human Prostatic Tissue -- Hormonal
Receptors in Human Prostate: A Computerized Study of Normal and Pathological Tissue Samples -- Androgen Receptors in Prostatic Cancer -- Transrectal Aspiration Biopsy of the Prostate with Franzen’s Instrument -- Treatment of Prostatic
Cancer with Medroxyprogesterone-Acetate (MPA) -- External Irradiation of Prostatic Cancer and Indicators for Failure of Treatment -- Intraurethral Irradiation of Prostatic Cancer using Afterloading Technique -- Review of the Veterans
Administration Studies of Cancer of the Prostate and New Results Concerning Treatment of Stage I and II Tumors -- Estracyt -- Combined Treatment with Bleomycin in Penile Carcinoma -- Association of Surgery and Chemotherapy in
Metastatic Testicular Cancer -- Speakers
ISBN:9781461330301
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:Ettore Majorana International Science Series, Life Sciences : 1
Keywords: Medicine , Oncology , Medicine & Public Health , Oncology
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Call number:SPRINGER-1978-9781475705553:ONLINE Show nearby items on shelf
Title:Applied General Systems Research Recent Developments and Trends
Author(s):
Date:1978
Size:1 online resource (1001 p.)
Note:10.1007/978-1-4757-0555-3
Contents:Conceptual and Methodological Foundations of General Systems Research -- Progress in General Systems Research -- Linkage Propositions between Fifty Principal Systems Concepts -- A Problem-Solving Basis for General Systems Research --
Systems Theoretic Description: A Vehicle for Reconciling Diverse Modelling Concepts -- On Being Autonomous: The Lessons of Natural History for Systems Theory -- The Complexity Race -- General System Identification — Fundamentals and
Results -- Constraint Analysis in Structure Modelling: A Probabilistic Approach -- Structure Modelling: A Constraint (Information) Analytic Approach -- On Structure Identification of Discrete Time Systems -- Metasystem Identification:
A Procedure for Detection and Structural Composition in Time Dependent Systems -- Exploring, Modelling, and Controlling Discrete Sequential Environments -- Managing Complex Systems: An Application of Ensemble Methods in System Theory
-- The Evolution of Organization -- A Mathematical Foundation for System Synthesis -- On the Decomposition of General Systems: Simulation by Coupling Quotients -- Some Esomathematical Uses of Category Theory -- A Categorical Approach
to General Systems -- Systems as Bimodules -- Lattices of Controllable and Observable Spaces -- Results of Empirical Studies in Fuzzy Set Theory -- Building Fuzzy Systems Models -- Basic Cyclic Relators as a Description of
Multi-Levelled Systems -- Mobile Systems: Survey -- System Dynamics Versus Econometrics—An Approach for Synthesis -- Absolute Stability of General Systems -- Asymptoticity in General Systems -- Normed Networks: Their Mathematical
Theory and Applicability -- The Role of the Observer in Uniform Systems -- The Nature of Fundamentals, Applied to the Fundamentals of Nature -- The Whole and the Simultaneous -- Ego Development Through Induced Programming --
Structurally Invariant Linear Models of Structurally Varying Linear Systems -- Stability and Eigenvalue Monotonicity of Linear Systems -- New Approaches to Reduction of Computational Complexity in Signal Processing Systems -- Synthesis
of Complex Control Objects as an Integrated System -- Advances of General Systems Research in Biological Sciences -- Biology and Systems Research: An Overview -- Biological Systems Theory: Descriptive and Constructive Complementarity
-- Some Analogies of Hierarchical Order in Biology and Linguistics -- Functional Hierarchies in the Brain -- Controlled Markov Chain Models for Biological Hierarchies -- Succinct Representation in Neural Nets and General Systems -- A
Matrix Algebra for Neural Nets -- Stability of General Systems in Biological, Physical and Social Sciences -- The Structural-Functional Analysis of Interbehavioral Systems -- Some Aspects of Analysis Cancer Problems by Means of Control
Theory -- The Inverse Problem: Computational Algorithms and Their Efficiency with Applications to a Model of the Calvin Photosynthesis Cycle -- Could a Model for the Regulation of ago-Antagonistic Couples Be Related to Various Types of
Concrete Systems? -- Optimal Ventilation of Critically Ill Patients -- Impact of General Systems Research On the Social Sciences -- Systems Research and Social Sciences -- Social System Evolution and Sociobiology -- General Systems
Methodology and Political Science -- Systems-Methodology in Management: An Adaptive Procedure for Organic Problem-Solving -- A Managerial Problem Solving Methodology (MPSM) -- A Dynamic Model for Society -- Understanding
Supra-Institutional Problems: Systems Lessons Drawn from an Application of the Checkland Methodology -- Multi-Organisational Strategies: An Analytical Framework and Case -- An Open-System Model of the Corporation -- A Production
Planning System Dynamics -- Analysis of Investment in Technology Development and Systems with Variable Structure -- General Systems: A Tool for the Evaluation of the Firm’s Potential as a Result of Changes in its P-M Posture -- Dynamic
Control of Hierarchical Public Systems -- The Meaning of Failure as Applied to Human Systems: Characteristics for a Fourth Generation of Systems Methodologies -- A Model of the Environment of Organizations: Theory and Evidence of
Regulating “Jumpy” F-Sets -- System Modeling in Space -- Social Networks and Inter-Systemic Decision-Making -- Two Separate Realities: Dyadic Communication Problems Resulting from Interpersonal Differences in Internal Complexity --
Evolution Strategy and Social Sciences -- A Systems Framework for Library Analysis -- Toward a Siggs Characterization of Epistemic Properties of Educational Design -- A Curriculum for General Systems Education -- Adverse Views to
General Systems Research -- Adverse Notes on Systems Theory -- On the Limitations of General Systems Theory in Systems Engineering -- The Limitations of Applied Systems Research
ISBN:9781475705553
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:NATO Conference Series : 5
Keywords: Science , Science, general , Science, general
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Call number:SPRINGER-1976-9783540381266:ONLINE Show nearby items on shelf
Title:Digital Picture Analysis
Author(s):
Date:1976
Size:1 online resource (1 p.)
Note:10.1007/3-540-07579-8
Contents:Automatic remote sensor image processing -- On radiographic image analysis -- Image processing in high energy physics -- Digital picture analysis in cytology -- Picture analysis in character recognition
ISBN:9783540381266
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:Topics in Applied Physics: 11
Keywords: Physics , Cancer research , Physics , Applied and Technical Physics , Cancer Research
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Call number:SPRINGER-1974-9781461344933:ONLINE Show nearby items on shelf
Title:Ultrasonic Imaging and Holography Medical, Sonar, and Optical Applications
Author(s):
Date:1974
Publisher:Boston, MA : Springer US
Size:1 online resource (644 p.)
Note:10.1007/978-1-4613-4493-3
Contents:Image Processing in Bio-Medical Engineering -- Ultrasonic Holography: A Practical System -- New Dimensions for R&D Program Management -- Ultrasonic Tissue Visualization and Surgery in Brain -- A Project of Ultrasonic Tomography
(“Sonoradiography”) -- Image Information Processing for Pulse Echo Scanning Methods -- Ultrasonic Imaging at Stanford Research Institute -- Optical Information Processing and Acousto-Optics -- Present Aspects of “Ultrasonotomography”
for Medical Diagnostics -- New Forms of Ultrasonic and Radar Imaging -- Acoustic Microscopy -- Some Aspects of Optical Holography that Might be of Interest for Acoustical Imaging -- Signal Processing Method in Ultra-Sconic Scanning
Technique -- Ultrasono-Cardio-Tomography -- Computer Processing of Ultrasonic Images -- Optical Image Improvement in Biomedical Electron Microscopy and Ultrasonics -- Ultrasonic Holography by Transducer Array and Liquid-Crystal Device
-- Holographic Synthetic Aperture Sonar System -- Present State of the Clinical Application of Ultrasonotomography -- Some Pathobiological Considerations of Detection of Breast Cancer by Ultrasonic Holography -- Biographies of
Contributors -- Author Index
ISBN:9781461344933
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Physics , Optics , Optoelectronics , Plasmons (Physics) , Physics , Optics, Optoelectronics, Plasmonics and Optical Devices
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Call number:SPRINGER-1957-9783642875441:ONLINE Show nearby items on shelf
Title:Morphological Astronomy
Author(s): F Zwicky
Date:1957
Size:1 online resource (299 p.)
Note:10.1007/978-3-642-87544-1
Contents:I: Morphological Research and Invention -- 1. Introductory Remarks -- 2. Random Intuition and Systematized Discovery, Research and Invention. Communicable Truth and Incommunicable Truth -- 3. The Formalism of Communicable Truth -- 4.
The Method of Negation and Subsequent Construction -- 5. The Morphological Method of Analysis and Construction -- 6. Past Applications of the Morphological Method -- 7. Deficiencies which Aid the Morphological Method -- 8. The Record
of the 18-inch Schmidt Telescope on Palomar Mountain -- 9. Specific Plans for a Morphological Approach to Astronomy -- II: Clouds and Clusters of Galaxies -- 10. The Known and the Unknown -- 11. The Large Scale Distribution of Matter
in the Universe -- 12. The Coma Cluster of Galaxies -- 13. Excursion into the Theory of Probabilities -- 14. Continuation of the Discussion on the Coma Cluster -- 15. The Cancer Cluster of Galaxies -- 16. The Pegasus Cluster of
Galaxies -- 17. Review of the Observations on the Clusters of Galaxies in Coma, Cancer and Pegasus -- 18. Irregular Clusters of Galaxies -- 19. Isopleths of Nebular Distribution -- III: The Large Scale Distribution of Galaxies and of
Clusters of Galaxies -- 20. Past and Present Views -- 21. Cluster Cells -- 22. The Field of the Coma Cluster -- 23. The Field of the Pegasus Cluster -- 24. The Field of the Corona Borealis Cluster -- 25. Various Statistical Methods in
the Field of Dimensionless Morphology. Contagion -- 26. Comparison of the Observed and of the Random Distribution Curves of Galaxies -- 27. Intergalactic Obscuration -- 28. Counts of Galaxies in Depth and in Width -- 29. Counts of
Galaxies in Dependence upon Apparent Magnitude -- IV: Kinematic and Dynamic Characteristics of the Large Scale Aggregates of Matter -- 30. The Velocities of Galaxies -- 31. Some Basic Problems Relating to the Universal Redshift -- 32.
Elements of a Theory of the Large Scale Distribution of Matter in the Universe -- 33. Dimensional Aspects of Large Scale Clustering -- 34. Hydrodynamical Concepts -- 35. Applications of the Virial Theorem to Clusters of Galaxies -- 36.
Clusters of Galaxies and the Emden Gravitational Isothermal Gas Sphere -- 37. A Possible Universal Characteristic Central Density of Clusters of Galaxies -- 38. Relative Physical Characteristics of Galaxies and of Clusters of Galaxies
-- V: Dimensional and Dimensionless Morphology in Cosmology -- 39. Appraisal of Past Approaches to the Exploration of Extragalactic Space -- 40. Methodology of Cosmological Research -- 41. Distribution of Clusters of Galaxies and their
Apparent Populations. Intergalactic Obscuration -- 42. The Frequency of Clusters of Galaxies as a Function of their Angular Diameters. Crucial Tests for the Theory of the Expanding Universe -- 43. The Total Space Occupied by the Large
Clusters of Galaxies -- 44. The Luminosity Function of Cluster Galaxies -- 45. Preliminary Test of the Theory of a Flat Expanding Universe -- 46. The Morphological Approach Toward the Determination of Absolute Dimensions and of
Absolute Physical Characteristics of Very Remote Objects -- 47. Remarks on the Morphology of Possible Cosmological Theories -- 48. The Einstein Redshift -- 49. The Gravitational Drag of Light -- VI: Morphological Features of Individual
Galaxies -- 50. References to the History of the Subject -- 51. Program for the Investigation of Individual Galaxies by the Methods of Dimensionless Morphology -- 52. The Kinematic and Dynamic Characteristics of Galaxies -- 53. The
Masses of Galaxies -- 54. Galaxies as Gravitational Lenses -- 55. The Luminosity Function of Galaxies -- 56. Multiple Galaxies and Intergalactic Matter -- VII: Morphological Astronomical Kaleidoscope -- 57. General Remarks -- 58.
Observations Made and Planned -- 59. Experimentation with Celestial Objects -- 60. Astrophysical Theories -- 61. Material Reconstruction of Parts of the Universe -- 62. Sociological Problems -- VIII: The Morphological Method and a
priori Knowledge. The Magic Numbers -- 63. Philosophy and Communicable Truth -- 64. The Irreducible Foundations of Communicable Truth -- 65. Some Specific Problems -- 66. Outstanding Transcendental Numbers -- 67. The Dimensionalities
used in Physics -- 68. Why is Space Three-Dimensional? -- 69. Other Magic Numbers -- 70. The Nature of the Physical Laws -- Epilogue -- Namelndex
ISBN:9783642875441
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Physics , Astronomy , Astrophysics , Cosmology , Physics , Astronomy, Astrophysics and Cosmology
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