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SPIRES-BOOKS: FIND KEYWORD CELL BIOLOGY *END*INIT* use /tmp/qspiwww.webspi1/11144.2 QRY 131.225.70.96 . find keyword cell biology ( in books using www Cover
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Call number:3527409297:ONLINE Show nearby items on shelf
Title:Laser Imaging and Manipulation in Cell Biology
Author(s): Pavone
Date:2010
Publisher:Wiley-VCH
Size:1 online resource (261 p.)
ISBN:9783527409297
Series:eBooks
Series:Wiley Online Library
Series:Wiley 2016 package purchase
Keywords: Electrical & Electronics Engineering
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Call number:SPRINGER-2016-9783319244488:ONLINE Show nearby items on shelf
Title:Physical Models of Cell Motility
Author(s):
Date:2016
Edition:1st ed. 2016
Size:1 online resource (9 p.)
Note:10.1007/978-3-319-24448-8
Contents:Introduction -- Phase-field Description of Cell Movement -- Role of Substrate Adhesiveness -- Cytoskeletal Waves -- Chemical Signaling -- Efficiency of Cell Motion
ISBN:9783319244488
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Physics , Bioinformatics , Computational biology , Biomathematics , Biophysics , Biological physics , Biomedical engineering , Physics , Biophysics and Biological Physics , Biomedical Engineering , Computer Appl. in Life Sciences , Numerical and Computational Physics , Physiological, Cellular and Medical Topics
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Call number:SPRINGER-2014-9783642390104:ONLINE Show nearby items on shelf
Title:Stochastic Foundations in Movement Ecology [electronic resource] : Anomalous Diffusion, Front Propagation and Random Searches
Author(s): Vicen Mndez
Daniel Campos
Frederic Bartumeus
Date:2014
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer
Size:1 online resource
Note:This book presents the fundamental theory for non-standard diffusion problems in movement ecology. Lvy processes and anomalous diffusion have shown to be both powerful and useful tools for qualitatively and quantitativelydescribing a wide variety of spatial population ecological phenomena and dynamics, such as invasion fronts and search strategies. Adopting a self-contained, textbook-style approach, the authors provide the elements of statisticalphysics and stochastic processes on which the modeling of movement ecology is based and systematically introduce the physical characterization of ecological processes at the microscopic, mesoscopic and macroscopic levels. The explicitdefinition of these levels and their interrelations is particularly suitable to coping with the broad spectrum of space and time scales involved in bio-ecological problems. Including numerous exercises (with solutions), this text isaimed at graduate students and newcomers in this field at the interface of theoretical ecology, ma thematical biology and physics
Contents:Elements of Probability Theory
Introduction to Stochastic Processes
Microscopic, Mesoscopic and Macroscopic Descriptions of Dispersal
Continuous
Time Random Walks and Anomalous Diffusion
Reaction
Dispersal Models and Front Propagation
Stochastic Optimal Foraging Theory
Cell Motion and Chemotaxis
Host
Pathogen Interactions
Biological Invasions
Random Search in Model Organisms
ISBN:9783642390104
Series:eBooks
Series:SpringerLink
Series:Springer Series in Synergetics, 0172-7389
Series:Physics and Astronomy (Springer-11651)
Keywords: Ecology , Genetics Mathematics , Engineering
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Call number:SPRINGER-2014-9783642387807:ONLINE Show nearby items on shelf
Title:Micro-Segmented Flow [electronic resource] : Applications in Chemistry and Biology
Author(s): J. Michael Khler
Brian P Cahill
Date:2014
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer
Size:1 online resource
Note:The book is dedicated to the method and application potential of micro segmented flow. The recent state of development of this powerful technique is presented in 12 chapters by leading researchers from different countries. In thefirst section, the pr inciples of generation and manipulation of micro-fluidic segments are explained. In the second section, the micro continuous-flow synthesis of different types of nanomaterials is shown as a typical example for theuse of advantages of the technique in chem istry. In the third part, the particular importance of the technique in biotechnical applications is presented demonstrating the progress for miniaturized cell-free processes, for molecularbiology and DNA-based diagnostis and sequencing as well as for the development of antibiotics and the evaluation of toxic effects in medicine and environment
Contents:From the Contents: Part I Generation, manipulation and characterization of micro fluid segments
Microfluidic droplets on rails and anchors: fluid manipulation and single cell analysis
Part II Chemical application in micro continuous
flow synthesis of nanoparticles
Solid particle handling in micro reaction technology
practical challenges and application of micro fluid segments for particle
based processes
Part III Biological application: cell
free biotechnology, cell cultivation and screening systems
Application of micro fluid segments in cell
free biotechnology
ISBN:9783642387807
Series:eBooks
Series:SpringerLink
Series:Biological and Medical Physics, Biomedical Engineering, 1618-7210
Series:Physics and Astronomy (Springer-11651)
Keywords: Biotechnology , Nanotechnology
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Call number:SPRINGER-2014-9781461495215:ONLINE Show nearby items on shelf
Title:Computational Methods for Three-Dimensional Microscopy Reconstruction [electronic resource]
Author(s): Gabor T Herman
Joachim Frank
Date:2014
Publisher:New York, NY : Springer New York : Imprint: Birkhuser
Size:1 online resource
Note:Approaches to the recovery of three-dimensional information on a biological object, which are often formulated or implemented initially in an intuitive way, are concisely described here based on physical models of the object andthe image-formation pr ocess. Both three-dimensional electron microscopy and X-ray tomography can be captured in the same mathematical framework, leading to closely-related computational approaches, but the methodologies differ indetail and hence pose different challenges. The editors of this volume, Gabor T. Herman and Joachim Frank, are experts in the respective methodologies and present research at the forefront of biological imaging and structural biology. Computational Methods for Three-Dimensional Microscopy Reconstructio n will serve as a useful resource for scholars interested in the development of computational methods for structural biology and cell biology, particularly in thearea of 3D imaging and modeling
Contents:1 Introduction
2 Interchanging geometry conventions in 3DEM: Mathematical context for the development of standards
3 Fully automated particle selection and verification in single
particle cryo
EM
4 Quantitative analysis in iterative classification schemes for cryo
EM applications
5 High
resolution cryo
EM structure of the Trypanosoma brucei ribosome of a case study
6 Computational methods for electron tomography of influenza virus
7 Reconstruction from microscopic projections with defocus
gradient and attenuation effects
8 Soft X
ray tomography imaging for biological sampl
ISBN:9781461495215
Series:eBooks
Series:SpringerLink
Series:Applied and Numerical Harmonic Analysis, 2296-5009
Series:Mathematics and Statistics (Springer-11649)
Keywords: Mathematics , Bioinformatics , Physiology Mathematics , Visualization , Cell aggregation Mathematics
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Call number:SPRINGER-2013-9781461443704:ONLINE Show nearby items on shelf
Title:Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems [electronic resource]
Author(s): Marc Thiriet
Date:2013
Publisher:New York, NY : Springer New York : Imprint: Springer
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. Thecardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls,macroscopic flow behavior and prediction must be coupled to p henomenological models of nano- and microscopic events in a corrector scheme of regulated mechanisms when the vessel lumen caliber varies markedly. Therefore, investigationof flows of blood and air in physiological conduits requires an understanding of th e biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning. Volume 4 is devoted to major setsof intracellular mediators that transmit signals upon stimulation of cell-surface receptors. Activation of signaling effectors triggers the release of substances stored in cellular organelles and/or gene transcription and proteinsynthesis. Complex stages of cell signaling can be studied using proper mathematical models, once the role of each component is c arefully handled. Volume 4 also reviews various categories of cytosolic and/or nuclear mediators andillustrates some major signal transduction pathways, such as NFkappaB axis, oxygen sensing, and mechanotransduction. Reviews signaling pathways in the regu lation of circulatory and respiratory function Describes ion and molecularcarriers and receptors Integrates biology, chemistry, and physics for a multidisciplinary understanding of physiological flows
Note:Springer eBooks
Contents:1. Introduction
2. Signaling Lipids
3. Preamble to Cytoplasmic Protein Kinases
4. Cytoplasmic Protein Tyrosine Kinases
5. Cytoplasmic Protein Serine/Threonine Kinases
6. Dual
Specificity Protein Kinases
7. Mitogen
Activated Protein Kinase Module
8. Dual
Specificity Protein Kinases
9. Guanosine Triphosphatases and Their Regulators
10. Other Major Types of Signaling Mediators
11. Signaling Pathways
12. Conclusion
References
List of Currently Used Prefixes and Suffixes
List of Aliases
Complementary Lists of Notations
Index
ISBN:9781461443704
Series:e-books
Series:SpringerLink (Online service)
Series:Biomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems, 2193-1682 : v4
Series:Physics and Astronomy (Springer-11651)
Keywords: Cardiology , Biological models , Hydraulic engineering , Biomedical engineering
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Call number:SPRINGER-2012-9783642303937:ONLINE Show nearby items on shelf
Title:The Dual Nature of Life [electronic resource]
Author(s): Gennadiy Zhegunov
Date:2012
Publisher:Springer Berlin Heidelberg
Size:1 online resource
Note:Popular science
Note:Springer 2012 Physics and Astronomy eBook collection
Note:Springer e-book platform
ISBN:9783642303937
Series:The Frontiers Collection
Series:e-books
Keywords: Evolutionary Biology , Popular Science, general , Cell Biology
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Call number:SPRINGER-2012-9783642282522:ONLINE Show nearby items on shelf
Title:Raman Imaging [electronic resource] : Techniques and Applications
Author(s): Arnaud Zoubir
Date:2012
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Raman imaging has long been used to probe the chemical nature of a sample, providing information on molecular orientation, symmetry and structure with sub-micron spatial resolution. Recent technical developments have pushed thelimits of micro-Raman m icroscopy, enabling the acquisition of Raman spectra with unprecedented speed, and opening a pathway to fast chemical imaging for many applications from material science and semiconductors to pharmaceutical drugdevelopment and cell biology, and even art a nd forensic science. The promise of tip-enhanced raman spectroscopy (TERS) and near-field techniques is pushing the envelope even further by breaking the limit of diffraction and enablingnano-Raman microscopy
Note:Springer eBooks
Contents:Instrumentation:
Theory and instrumentation
Imaging modes
Micro
Raman Applications:
Raman imaging in Semiconductor Physics and its application in Microelectronics
Raman optimization of the properties of nano
phased materials
Raman Imaging of meso
and nano
strutured materials
Application of Raman
based images in the Earth sciences
Uses of Raman Mapping and Imaging in Pharmaceutical Forensics
Raman Microscopy: A Versatile Approach to Bio
imaging
Mapping chemical and structural composition of biological and pharmaceutical samples by Raman and Surface
enhanced Raman
ISBN:9783642282522
Series:e-books
Series:SpringerLink (Online service)
Series:Springer Series in Optical Sciences, 0342-4111 : v168
Series:Physics and Astronomy (Springer-11651)
Keywords: Chemistry, Physical organic , Microscopy
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Call number:SPRINGER-2012-9783642252112:ONLINE Show nearby items on shelf
Title:Biophysics [electronic resource]
Author(s): Roland Glaser
Date:2012
Edition:2nd ed. 2012
Publisher:Springer Berlin Heidelberg
Size:1 online resource
Note:Graduate/advanced undergraduate textbook
Note:Springer 2012 Physics and Astronomy eBook collection
Note:Springer e-book platform
ISBN:9783642252112
Series:e-books
Keywords: Biophysics and Biological Physics , Biochemistry, general , Human Physiology , Effects of Radiation/Radiation Protection , Cell Biology
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Call number:SPRINGER-2012-9783642239878:ONLINE Show nearby items on shelf
Title:Formation and Cooperative Behaviour of Protein Complexes on the Cell Membrane [electronic resource]
Author(s): Ksenia Guseva
Date:2012
Publisher:Springer Berlin Heidelberg
Size:1 online resource
Note:Monograph
Note:Springer 2012 Physics and Astronomy eBook collection
Note:Springer e-book platform
ISBN:9783642239878
Series:Springer Theses
Series:e-books
Keywords: Membranes , Membrane Biology , Statistical Physics, Dynamical Systems and Complexity , Polymer Sciences
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Call number:SPRINGER-2012-9781461421511:ONLINE Show nearby items on shelf
Title:Molecular Theory of the Living Cell [electronic resource]
Author(s): Sungchul Ji
Date:2012
Publisher:Springer New York
Size:1 online resource
Note:Monograph
Note:Springer 2012 Physics and Astronomy eBook collection
Note:Springer e-book platform
ISBN:9781461421511
Series:e-books
Keywords: Biophysics and Biological Physics , Bioorganic Chemistry , Philosophy of Biology
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Call number:SPRINGER-2012-9781461419907:ONLINE Show nearby items on shelf
Title:Signaling at the Cell Surface in the Circulatory and Ventilatory Systems [electronic resource]
Author(s): Marc Thiriet
Date:2012
Publisher:Springer New York
Size:1 online resource
Note:Monograph
Note:Springer 2012 Physics and Astronomy eBook collection
Note:Springer e-book platform
ISBN:9781461419907
Series:Biomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems
Series:e-books
Keywords: Biophysics and Biological Physics , Biomedical Engineering , Mathematical and Computational Biology , Systems Biology , Engineering Fluid Dynamics , Cardiology
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Call number:SPRINGER-2012-9781461403289:ONLINE Show nearby items on shelf
Title:Control of Cell Fate in the Circulatory and Ventilatory Systems [electronic resource]
Author(s): Marc Thiriet
Date:2012
Publisher:Springer New York
Size:1 online resource
Note:Monograph
Note:Springer 2012 Physics and Astronomy eBook collection
Note:Springer e-book platform
ISBN:9781461403289
Series:Biomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems
Series:e-books
Keywords: Biophysics and Biological Physics , Biomedical Engineering , Mathematical and Computational Biology , Systems Biology , Engineering Fluid Dynamics , Cardiology
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Call number:SPRINGER-2011-9783642156373:ONLINE Show nearby items on shelf
Title:The Mathematics of Knots [electronic resource] Theory and Application
Author(s): Markus Banagl
Denis Vogel
Date:2011
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:The present volume grew out of the Heidelberg Knot Theory Semester, organized by the editors in winter 2008/09 at Heidelberg University. The contributed papers bring the reader up to date on the currently most actively pursuedareas of mathematical kn ot theory and its applications in mathematical physics and cell biology. Both original research and survey articles are presented numerous illustrations support the text. The book will be of great interest toresearchers in topology, geometry, and mathemat ical physics, graduate students specializing in knot theory, and cell biologists interested in the topology of DNA strands
Note:Springer eBooks
Contents:Preface
1 Knots, Singular Embeddings, and Monodromy
2 Lower Bounds on Virtual Crossing Number and Minimal Surface Genus
3 A Survey of Twisted Alexander Polynomials
4 On Two Categorifications of the Arrow Polynomial for Virtual Knots
5 An Adelic Extension of the Jones Polynomial
6 Legendrian Grid Number One Knots and Augmentations of their Differential Algebras
7 Embeddings of Four
Valent Framed Graphs into 2
Surfaces
8 Geometric Topology and Field Theory on 3
Manifolds
9 From Goeritz Matrices to Quasi
Alternating Links
10 An Overview of Property 2R
11 DNA, Knot
ISBN:9783642156373
Series:e-books
Series:SpringerLink (Online service)
Series:Contributions in Mathematical and Computational Sciences : v1
Series:Mathematics and Statistics (Springer-11649)
Keywords: Mathematics , Physiology Mathematics , Global differential geometry , Topology , Cell aggregation Mathematics
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Call number:SPRINGER-2009-9783540708407:ONLINE Show nearby items on shelf
Title:Non-Protein Coding RNAs [electronic resource]
Author(s): Nils G Walter
Sarah A Woodson
Robert T Batey
Date:2009
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:This book assembles chapters from experts in the Biophysics of RNA to provide a broadly accessible snapshot of the current status of this rapidly expanding field. The 2006 Nobel Prize in Physiology or Medicine was awarded to thediscoverers of RNA int erference, highlighting just one example of a large number of non-protein coding RNAs. Because non-protein coding RNAs outnumber protein coding genes in mammals and other higher eukaryotes, it is now thought thatthe complexity of organisms is correlated w ith the fraction of their genome that encodes non-protein coding RNAs. Essential biological processes as diverse as cell differentiation, suppression of infecting viruses and parasitictransposons, higher-level organization of eukaryotic chromosomes, and g ene expression itself are found to largely be directed by non-protein coding RNAs. The biophysical study of these RNAs employs X-ray crystallography, NMR, ensembleand single molecule fluorescence spectroscopy, optical tweezers, cryo-electron microscopy, a nd other quantitative tools. This emerging field has begun to unravel the molecular underpinnings of how RNAs fulfill their multitude of rolesin sustaining cellular life. The physical and chemical understanding of RNA biology that results from biophysical studies is critical to our ability to harness RNAs for use in biotechnology and human therapy, a prospect that hasrecently spawned a multi-billion dollar industry
Note:Springer eBooks
ISBN:9783540708407
Series:e-books
Series:SpringerLink (Online service)
Series:Springer Series in Biophysics, 0932-2353 : v13
Series:Physics and Astronomy (Springer-11651)
Keywords: Medicine , Biochemistry , Bioinformatics , Cytology , Biomedical engineering
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Call number:SPRINGER-2009-9780387793887:ONLINE Show nearby items on shelf
Title:Mathematical Physiology [electronic resource] : II: Systems Physiology
Author(s): James Keener
James Sneyd
Date:2009
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:There has been a long history of interaction between mathematics and physiology. This book looks in detail at a wide selection of mathematical models in physiology, showing how physiological problems can be formulated and studiedmathematically, and h ow such models give rise to interesting and challenging mathematical questions. With its coverage of many recent models it gives an overview of the field, while many older models are also discussed, to put themodern work in context. In this second edition the coverage of basic principles has been expanded to include such topics as stochastic differential equations, Markov models and Gibbs free energy, and the selection of models has alsobeen expanded to include some of the basic models of fluid transport, respiration/perfusion, blood diseases, molecular motors, smooth muscle, neuroendrocine cells, the baroreceptor loop, turboglomerular oscillations, blood clotting andthe retina. Owing to this extensive coverage, the second edition is published in two volu mes. This second volume deals with the physiology of systems and the first volume with the fundamental principles of cell physiology. The bookincludes detailed illustrations and numerous excercises with selected solutions. The emphasis throughout is on th e applications because of this interdisciplinary approach, this book will be of interest to students and researchers, notonly in mathematics, but also in bioengineering, physics, chemistry, biology, statistics and medicine. James Keener is a Distinguished Professor of Mathematics at the University of Utah. He and his wife live in Salt Lake City, butdon't be surprised if he moves to the mountains. James Sneyd is the Professor of Applied Mathematics at the University of Auckland in New Zealand, where he has worked for the past six years. He lives with his wife and three childrenbeside a beach, and would rather be swimming. Reviews of the first edition: ...probably the best book ever written on the interd
Note:Springer eBooks
ISBN:9780387793887
Series:e-books
Series:SpringerLink (Online service)
Series:Interdisciplinary Applied Mathematics, 0939-6047 : v8/2
Series:Mathematics and Statistics (Springer-11649)
Keywords: Mathematics , Human physiology , Biology Mathematics
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Call number:SPRINGER-2009-9780387758473:ONLINE Show nearby items on shelf
Title:Mathematical Physiology [electronic resource] : I: Cellular Physiology
Author(s): James Keener
James Sneyd
Date:2009
Publisher:New York, NY : Springer New York : Imprint: Springer
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:There has been a long history of interaction between mathematics and physiology. This book looks in detail at a wide selection of mathematical models in physiology, showing how physiological problems can be formulated and studiedmathematically, and h ow such models give rise to interesting and challenging mathematical questions. With its coverage of many recent models it gives an overview of the field, while many older models are also discussed, to put themodern work in context. In this second edition the coverage of basic principles has been expanded to include such topics as stochastic differential equations, Markov models and Gibbs free energy, and the selection of models has alsobeen expanded to include some of the basic models of fluid transport, respiration/perfusion, blood diseases, molecular motors, smooth muscle, neuroendrocine cells, the baroreceptor loop, turboglomerular oscillations, blood clotting andthe retina. Owing to this extensive coverage, the second edition is published in two volu mes. This first volume deals with the fundamental principles of cell physiology and the second with the physiology of systems. The book includesdetailed illustrations and numerous excercises with selected solutions. The emphasis throughout is on the appli cations because of this interdisciplinary approach, this book will be of interest to students and researchers, not only inmathematics, but also in bioengineering, physics, chemistry, biology, statistics and medicine. James Keener is a Distinguished Profes sor of Mathematics at the University of Utah. He and his wife live in Salt Lake City, but don't besurprised if he moves to the mountains. James Sneyd is the Professor of Applied Mathematics at the University of Auckland in New Zealand, where he has worked for the past six years. He lives with his wife and three children beside abeach, and would rather be swimming. Reviews of the first edition: ...probably the best book ever written on the interdiscipli
Note:Springer eBooks
Contents:Cellular Physiology
Biochemical Reactions
Cellular Homeostasis
Membrane Ion Channels
Passive Electrical Flow in Neurons
Excitability
Traveling Waves of Electrical Excitation
Wave Propagation in Higher Dimensions
Calcium Dynamics
Intercellular Communication
Neuroendocrine Cells
Regulation of Cell Function
ISBN:9780387758473
Series:e-books
Series:SpringerLink (Online service)
Series:Interdisciplinary Applied Mathematics, 0939-6047 : v8/1
Series:Mathematics and Statistics (Springer-11649)
Keywords: Mathematics , Human physiology
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Call number:SPRINGER-2008-9783540738497:ONLINE Show nearby items on shelf
Title:Unifying Themes in Complex Systems IV [electronic resource] : Proceedings of the Fourth International Conference on Complex Systems
Author(s): Ali A Minai
Yaneer Bar-Yam
Date:2008
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:In June of 2002, over 500 professors, students and researchers met in Boston, Massachusetts for the Fourth International Conference on Complex Systems. The attendees represented a remarkably diverse collection of fields: biology,ecology, physics, eng ineering, computer science, economics, psychology and sociology, The goal of the conference was to encourage cross-fertilization between the many disciplines represented and to deepen understanding of theproperties common to all complex systems. This volu me contains 43 papers selected from the more than 200 presented at the conference. Topics include: cellular automata, neurology, evolution, computer science, network dynamics, andurban planning. About NECSI: For over 10 years, The New England Complex Syst ems Institute (NECSI) has been instrumental in the development of complex systems science and its applications. NECSI conducts research, education, knowledgedissemination, and community development around the world for the promotion of the study of comple x systems and its application for the betterment of society. NECSI hosts the International Conference on Complex Systems and publishesthe NECSI Book Series in conjunction with Springer Publishers. ALI MINAI is an Affiliate of the New England Complex Syste ms Institute and an Associate Professor in the Department of Electrical and Computer Engineering and ComputerScience at the University of Cincinnati. YANEER BAR-YAM is President and founder of the New England Complex Systems Institute. He is the author of Dynamics of Complex Systems and Making Things Work: Solving Complex Problems in aComplex World
Note:Springer eBooks
Contents:Methods
A Complex Systems Perspective on Collaborative Design
RAn (Robustness Analyser)
Invariant Subsets of the Search Space, and the Universality of a Generalized Genetic Algorithm
Models
Cell
like space charge configurations formed by self
organization in laboratory
Local Complexity and Global Nonlinear Modes in Large Arrays of Elastic Rods in an Air Cross
Flow
Self
organization in Navier
Stokes turbulence
The Game (Introduction to Digital Physics)
Epsilon
Pseudo
Orbits and Applications
On the mystery of differential negative resistance
Dissipative Str
ISBN:9783540738497
Series:e-books
Series:SpringerLink (Online service)
Series:Physics and Astronomy (Springer-11651)
Keywords: Artificial intelligence , Mathematics , Engineering
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Call number:SPRINGER-2008-9781402087615:ONLINE Show nearby items on shelf
Title:Evolution from Cellular to Social Scales [electronic resource]
Author(s): Arne T Skjeltorp
Alexander V Belushkin
Date:2008
Publisher:Dordrecht : Springer Netherlands
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Evolution is a critical challenge for many areas of science, technology and development of society. The book reviews general evolutionary facts such as origin of life and evolution of the genome and clues to evolution throughsimple systems. Emerging areas of science such as systems biology and bio-complexity are founded on the idea that phenomena need to be understood in the context of highly interactive processes operating at different levels andon different scales. This is where physics meets compl exity in nature, and where we must begin to learn about complexity if we are to understand it. Similarly, there is an increasingly urgent need to understand and predict theevolutionary behavior of highly interacting man-made systems, in areas such as comm unications and transport, which permeate the modern world. The same applies to the evolution of human networks such as social, political and financialsystems, where technology has tended to vastly increase both the complexity and speed of interaction, whi ch is sometimes effectively instantaneous. The book contains reviews on such diverse areas as evolution experiments withmicroorganisms, the origin and evolution of viruses, evolutionary dynamics of genes and environment in cancer development, aging as an evolution-facilitating program, evolution of vision and evolution of financial markets
Note:Springer eBooks
Contents:The Accuracy of Molecular Processes
Experimental Evolution: Bugs and Bytes
Evolutionary Dynamics
Small RNA Control of Cell
to
Cell Communication in Vibrio Harveyi and Vibrio Cholerae
Dynamical Genetic Regulation
Translation Attenuation Mechanism in Unfolded Protein Response
The Origin and Evolution of Viruses
Fokker
Planck and Chapman
Kolmogorov Equations for Ito Processes with Finite Memory
Evolution of FX Markets via Globalization of Capital
Evolutionary Dynamics of Genes and Environment in Cancer Development
Aging as Evolution
Facilitating Program and a Biochem
ISBN:9781402087615
Series:e-books
Series:SpringerLink (Online service)
Series:NATO Science for Peace and Security Series B: Physics and Biophysics, 1874-6500
Series:Physics and Astronomy (Springer-11651)
Keywords: Evolution (Biology) , Biomedical engineering , Engineering , Economics
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Call number:SPRINGER-2008-9781402082689:ONLINE Show nearby items on shelf
Title:Integrated Molecular and Cellular Biophysics [electronic resource]
Author(s): Valerica Raicu
Aurel Popescu
Date:2008
Publisher:Dordrecht : Springer Netherlands
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:This book integrates concepts and methods from physics, biology, biochemistry and physical chemistry into a standalone, unitary text of biophysics that aims to provide a quantitative description of structures and processesoccurring in living matter. The book introduces graduate physics students and physicists interested in biophysics research to 'classical' as well as emerging areas of biophysics. The advanced undergraduate physics students and the lifescientists are also invited to join in, by build ing on their knowledge of basic physics. Essential notions of biochemistry and biology are introduced, as necessary, throughout the book, while the reader's familiarity with basicknowledge of physics is assumed. Topics covered include interactions between biological molecules, physical chemistry of phospholipids association into bilayer membranes, DNA and protein structure and folding, passive and activeelectrical properties of the cell membrane, classical as well as fractal aspects of reaction kinetics a nd diffusion in biological systems, structural and functional aspects of molecular machines (including channels, ion pumps, andlight-harvesting antenna), as well as fundamental aspects of proteins association in solutions and in living cells
Note:Springer eBooks
ISBN:9781402082689
Series:e-books
Series:SpringerLink (Online service)
Series:Physics and Astronomy (Springer-11651)
Keywords: Chemistry, Physical organic , Life sciences , Physiology Mathematics
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Call number:SPRINGER-2008-9780387772592:ONLINE Show nearby items on shelf
Title:Physics of the Life Sciences [electronic resource]
Author(s): Jay Newman
Date:2008
Publisher:New York, NY : Springer New York : Imprint: Springer
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Originally developed for the author's course at Union College, this text is designed for life science students who need to understand the connections of fundamental physics to modern biology and medicine. Almost all areas ofmodern life sciences integ rally involve physics in both experimental techniques and in basic understanding of structure and function. Physics of the Life Sciences is not a watered-down, algebra-based engineering physics book withsections on relevant biomedical topics added as an a fterthought. This authoritative and engaging text, which is designed to be covered in a two-semester course, was written with a thoroughgoing commitment to the needs and interests oflife science students. Although covering most of the standard topics in i ntroductory physics in a more or less traditional sequence, the author gives added weight and space to concepts and applications of greater relevance to the lifesciences. Students benefit from occasional sidebars using calculus to derive fundamental relat ions, but only algebra and trigonometry are used to explore the basic physical concepts in the main body of the text and to solveend-of-chapter problems
Note:Springer eBooks
Contents:Introduction
Newtons Laws of Motion for a Particle Moving in One
Dimension
Applications of Newtons Laws of Motion in One
Dimension
Work and Energy in One
Dimension
Motion, Forces and Energy in More than One
Dimension
Momentum
Rotational Motion
Ideal Fluids
Viscous Fluids
Waves and Resonance
Sound
Temperature and Heat
Thermodynamics: Beyond the First Law
Electric Forces and Fields
Electric Energy and Potential
Electric Current and Cell Membranes
Magnetic Fields
Electromagnetic Induction and Radiation
Electromagnetic Waves
Geometrica
ISBN:9780387772592
Series:e-books
Series:SpringerLink (Online service)
Series:Physics and Astronomy (Springer-11651)
Keywords: Biomedical engineering
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Call number:SPRINGER-2008-9780387748474:ONLINE Show nearby items on shelf
Title:Biology and Mechanics of Blood Flows [electronic resource] : Part I: Biology
Author(s): Marc Thiriet
Date:2008
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Biology and Mechanics of Blood Flows presents the basic knowledge and state-of-the-art techniques necessary to carry out investigations of the cardiovascular system using modeling and simulation. Part I of this two-volumesequence, Biology, addresses the nanoscopic and microscopic scales. The nanoscale corresponds to the scale of biochemical reaction cascades involved in cell adaptation to mechanical stresses among other stimuli. The microscale is thescale of stress-induced tissue remodeling associate d with acute or chronic loadings. The cardiovascular system, like any physiological system, has a complicated three-dimensional structure and composition. Its time dependent behavioris regulated, and this complex system has many components. In this author itative work, the author provides a survey of relevant cell components and processes, with detailed coverage of the electrical and mechanical behaviors ofvascular cells, tissues, and organs. Because the behaviors of vascular cells and tissues are tightly coupled to the mechanics of flowing blood, the major features of blood flows and the Navier-Stokes equations of mass and momentumconservation are introduced at the conclusion of this volume. This book will appeal to any biologist, chemist, physicist, or a pplied mathematician with an interest in the functioning of the cardiovascular system
Note:Springer eBooks
Contents:The Cell
Plasma Membrane and Cell Environment
Ion Carriers and Receptors
Signaling Pathways
Transport and Cell Motion
Blood
Heart Wall
Vessel Wall
Endothelium
Tissue Growth, Repair, and Remodeling
ISBN:9780387748474
Series:e-books
Series:SpringerLink (Online service)
Series:CRM Series in Mathematical Physics
Series:Physics and Astronomy (Springer-11651)
Keywords: Cardiology , Materials , Biomedical engineering
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Call number:SPRINGER-2008-9780387730509:ONLINE Show nearby items on shelf
Title:Cell Motility [electronic resource]
Author(s): Peter Lenz
Date:2008
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Cell motility is a fascinating example of cell behavior which is fundamentally important to a number of biological and pathological processes. It is based on a complex self-organized mechano-chemical machine consisting ofcytoskeletal filaments and mo lecular motors. In general, the cytoskeleton is responsible for the movement of the entire cell and for movements within the cell. The main challenge in the field of cell motility is to develop a completephysical description on how and why cells move. For this purpose new ways of modeling the properties of biological cells have to be found. This long term goal can only be achieved if new experimental techniques are developed to extractphysical information from these living systems and if theoretical model s are found which bridge the gap between molecular and mesoscopic length scales. Cell Motility gives an authoritative overview of the fundamental biological facts,theoretical models, and current experimental developments in this fascinating area
Note:Springer eBooks
Contents:The Physics Of Listeria Propulsion
Biophysical Aspects of Actin
Based Cell Motility in Fish Epithelial Keratocytes
Directed Motility and Dictyostelium Aggregation
Microtubule Forces and Organization
Mechanisms of Molecular Motor Action and Inaction
Molecular Mechanism of Mycoplasma Gliding
A Novel Cell Motility System
Hydrodynamics and Rheology of Active Polar Filaments
Collective Effects in Arrays of Cilia and Rotational Motors
ISBN:9780387730509
Series:e-books
Series:SpringerLink (Online service)
Series:Biological and Medical Physics, Biomedical Engineering, 1618-7210
Series:Physics and Astronomy (Springer-11651)
Keywords: Human physiology , Cytology , Aquatic biology , Biomedical engineering
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Call number:SPRINGER-2007-9783764381233:ONLINE Show nearby items on shelf
Title:Single-Cell-Based Models in Biology and Medicine [electronic resource]
Author(s): Alexander R. A Anderson
Mark A. J Chaplain
Katarzyna A Rejniak
Date:2007
Publisher:Basel : Birkhuser Basel
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:To adequately describe complex spatio-temporal processes that occur in multi-cellular organisms, a class of models is required that simultaneously takes into account differences between individual cells as well as their ability tocommunicate and inte ract with one another and their environment. Single-cell-based models form a framework that allows for the explicit incorporation of different properties of individual cells, but at the same time enables all cellsto act together as one collective body. Th is leads ultimately to more biologically realistic models of heterogeneous tissues and multi-cellular organisms and allows for a better understanding of the principles underlying the complexbiological processes occurring during the formation, growth and m aintenance of multi-cellular bodies. The aim of this book is to assemble a collection of different mathematical and computational models and techniques that focus onindividual cells, cell processes and cell behaviour, that are also suitable to address pro blems on the multi-cellular or tissue scale. We would like to focus the level of the book equally to students starting their research in thefield of mathematical biology and to scientists already modelling multi-cellular processes. Therefore, our intentio n is to include in this book a detailed description of each model and an extensive review of suitable biological andmedical applications
Note:Springer eBooks
Contents:Hybrid Multiscale Models
A Hybrid Multiscale Model of Solid Tumour Growth and Invasion: Evolution and the Microenvironment
Lattice
gas Cellular Automaton Modeling of Developing Cell Systems
Two
dimensional Multiscale Model of Cell Motion in a Chemotactic Field
The Cellular Potts Model and Its Variants
Magnetization to Morphogenesis: A Brief History of the Glazier
Graner
Hogeweg Model
The Cellular Potts Model and Biophysical Properties of Cells, Tissues and Morphogenesis
The Cellular Potts Model in Biomedicine
The Glazier
Graner
Hogeweg Model: Extensions, Future Directio
ISBN:9783764381233
Series:e-books
Series:SpringerLink (Online service)
Series:Mathematics and Biosciences in Interaction
Series:Mathematics and Statistics (Springer-11649)
Keywords: Mathematics , Biology Mathematics
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Call number:SPRINGER-2007-9783764378424:ONLINE Show nearby items on shelf
Title:Transport Equations in Biology [electronic resource]
Author(s): Benot Perthame
Date:2007
Publisher:Basel : Birkhuser Basel
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:This book presents models written as partial differential equations and originating from various questions in population biology, such as physiologically structured equations, adaptive dynamics, and bacterial movement. Its purposeis to derive appropr iate mathematical tools and qualitative properties of the solutions (long time behavior, concentration phenomena, asymptotic behavior, regularizing effects, blow-up or dispersion). Original mathematical methodsdescribed are, among others, the generalized relative entropy method - a unique method to tackle most of the problems in population biology, the description of Dirac concentration effects using a new type of Hamilton-Jacobi equations,and a general point of view on chemotaxis including various scales of description leading to kinetic, parabolic or hyperbolic equations
Note:Springer eBooks
Contents:Preface
1. From Differential Equations to Structured Population Dynamics
2. Adaptive Dynamics an Asymptotic Point of View
3. Population Balance Equations: the Renewal Equation
4. Population Balance Equations: Size Structure
5. Cell Motion and Chemotaxis
6. General Mathematical Tools
Bibliography
Index
ISBN:9783764378424
Series:e-books
Series:SpringerLink (Online service)
Series:Frontiers in Mathematics, 1660-8046
Series:Mathematics and Statistics (Springer-11649)
Keywords: Mathematics , Differentiable dynamical systems , Differential Equations , Biology Mathematics
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Call number:SPRINGER-2007-9783540464273:ONLINE Show nearby items on shelf
Title:Applications of Synchrotron Radiation [electronic resource] : Micro Beams in Cell Micro Biology and Medicine
Author(s): Ari Ide-Ektessabi
Date:2007
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:This book demonstrates the applications of synchrotron radiation in certain aspects of cell microbiology, specifically non-destructive elemental analyses, chemical-state analyses and imaging (distribution) of the elements within acell. The basics for understanding and applications of synchrotron radiation are also described to make the contents easier to be understood for a wide group of researchers in medical and biological sciences who might not be familiarwith the physics of synchrotron radiation. The two main techniques that are discussed in this book are the x-ray fluorescence spectroscopy (XRF) and the x-ray fine structure analysis (XAFS). Application of these techniques ininvestigations of several important scientific fields, such as neurodege neration and other diseases related to cell malfunctioning, are demonstrated in this book
Note:Springer eBooks
Contents:Introduction
Synchrotron Radiation and X
ray Fluorescence Spectroscopy
X
ray Absorption Fine Structure Spectroscopy
SR Microbeam Analysis at Cellular Level
Investigation of Differentiation of Mouse ES Cells
Investigation of Neurodegenerative Disorders (I)
Investigation of Neurodegenerative Disorders (II)
SR Analysis of Tissues
ISBN:9783540464273
Series:e-books
Series:SpringerLink (Online service)
Series:Biological and Medical Physics, Biomedical Engineering, 1618-7210
Series:Physics and Astronomy (Springer-11651)
Keywords: Microscopy , Physical optics , Biomedical engineering
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Call number:SPRINGER-2007-9781402063008:ONLINE Show nearby items on shelf
Title:Problems of High Altitude Medicine and Biology [electronic resource]
Author(s): Almaz Aldashev
Robert Naeije
Date:2007
Publisher:Dordrecht : Springer Netherlands
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:This book is directly derived from a NATO-sponsored international meeting on problems of high altitude medicine and biology, which was held on the shores of lake of Issyk-Kul, in Kyrghyzstan, in June 5-6, 2006. It was a surprisefor several European a nd North and South-American scientists to discover the still on-going momentum high level altitude physiology research, which was extremely active but insufficiently acknowledged in this remote Central Asiancountry at the time of the USSR. Accordingly, th e setting was perfect for numerous positive scientific interactions, exchanges of ideas, and structuring of new international collaborations. Overall, the meeting was an ideal mix of cellbiology, integrative physiology and medical applications. Hypoxia is and remains a major public health issue in many populated mountainous areas all over the world. We are sure that this book will be become a long-lasting essentialreference
Note:Springer eBooks
Contents:1. 45 Years of mountain medicine
2. High altitude pulmonary hypertension and chronic mountain sickness
3. The Cellular effects of hypoxia on the pulmonary circulation
4. Angiogenesis and chronic hypoxic pulmonary hypertension
5. Tetrahydrobiopterin and pulmonary hypertension
6. Hypoxia
induced proliferation of human pulmonary arterial smooth muscle cell is involved in the suppression of cyclin
dependent kinase inhibitors
7. Pulmonary adaptation to high altitude in wild mammals
8. Lung at high altitude: between physiology and pathology
9. Sildenafil and hypoxic pulmonary
ISBN:9781402063008
Series:e-books
Series:SpringerLink (Online service)
Series:Mathematics and Statistics (Springer-11649)
Keywords: Mathematics , Cardiology , Pneumology , Sports medicine , Physiology Mathematics
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Call number:SPRINGER-2007-9781402059001:ONLINE Show nearby items on shelf
Title:Structure and Biophysics New Technologies for Current Challenges in Biology and Beyond [electronic resource]
Author(s): Joseph D Puglisi
Date:2007
Publisher:Dordrecht : Springer Netherlands
Size:1 online resource
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Note:This volume is a collection of articles from the proceedings of the ISSBMR 7th Course: Structure and Biophysics - New Technologies for Current Challenges in Biology and Beyond. This NATO Advanced Institute (ASI) was held in Ericeat the Ettore Majoran a Foundation and Centre for Scientific Culture on 22 June through 3 July 2005. The ASI brought together a diverse group of experts in the fields of Structural Biology, Biophysics and Physics. Prominent lecturers,from seven different countries, and student s from around the world participated in the NATO ASI organized by Professors Joseph Puglisi (Stanford University, USA) and Alexander Arseniev (Moscow, RU). Advances in nuclear magneticresonance spectroscopy (NMR) and x-ray crystallography have allowed the three-dimensional structures of many biological macromolecules and their complexes, including the ribosome and RNA polymerase to be solved. Fundamental principlesof NMR spectroscopy and dynamics, x-ray crystallography, computation and experimental dynami cs were taught in the context of important biological applications. The ASI addressed the treatment and detection of bioterrorism agents, andfocused on critical partner country priorities in biotechnology, materials and drug discovery. The range of topics represent the diversity of critical problems between structural biology, biochemistry and biophysics, in which lies thefertile ground of drug development, biotechnology and new materials. The individual articles represent the state of the art in each are a and provide a guide to the original literature in this rapidly developing field
Note:Springer eBooks
Contents:Preface
Structural Genomics by NMR Spectroscopy
Investigation of Proteins in Living Bacteria with in
Cell NMR Experiments
Protein
Membrane Interactions: Lessons from In Silico Studies
Anything Goes Protein Structural Polymorphism
Tandem Interactions in the trp Repressor System may Regulate Binding to Operator DNA
Basic Principles of RNA NMR Spectroscopy
Probabilistic Structure Calculation
Molecular Insights into PKR Activation by Viral Double
Stranded RNA
Structural Dynamic Approach as Rational Input for Drug Design
Max Perutz: Chemist, Molecular Biologist, Hu
ISBN:9781402059001
Series:e-books
Series:SpringerLink (Online service)
Series:NATO Science Series
Series:Physics and Astronomy (Springer-11651)
Keywords: Biotechnology , Particles (Nuclear physics) , Crystallography , Biomedical engineering
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Call number:SPRINGER-2007-9780387687339:ONLINE Show nearby items on shelf
Title:Killer Cell Dynamics [electronic resource] : Mathematical and Computational Approaches to Immunology
Author(s): Dominik Wodarz
Date:2007
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:This book reviews how mathematics can be used in combination with biological data in order to improve understanding of how the immune system works. This is illustrated largely in the context of viral infections. Mathematicalmodels allow scientists to capture complex biological interactions in a clear mathematical language and to follow them to their precise logical conclusions. This can give rise to counter-intuitive insights which would not be attainedby experiments alone, and can be used for the de sign of further experiments in order to address the mathematical results. This book provides both an introduction to the field of mathematical immunology, and an overview of many topicswhich are the subject of current research, covering a broad variety of immunological topics. It starts with basic principles of immunology and covers the dynamical interactions between the immune system and specific viral infections,including important human pathogens such as HIV. General biological and mathematical backgro und material to both virus infection and immune system dynamics is provided, and each chapter begins with a simple introduction to thebiological questions examined. This book is intended for an interdisciplinary audience. It explains the concept of mathem atical modeling in immunology and shows how modeling has been used to address specific questions. It is intendedboth for the mathematical biologists who are interested in immunology, and for the biological readership that is interested in the use of mathe matical models in immunology. Dominik Wodarz is an Associate Professor at the Department ofEcology and Evolutionary Biology at the University of California, Irvine
Note:Springer eBooks
Contents:Viruses and Immune Responses: A Dynamical View
Models of CTL Responses and Correlates of Virus Control
CTL Memory
CD4 T Cell Help
Immunodominance
Multiple Infections and CTL Dynamics
Control Versus CTL
Induced Pathology
Lytic Versus Nonlytic Activity
Dynamical Interactions Between CTL and Antibody Responses
Effector Molecules and CTL Homeostasis
Virus
Induced Subversion of CTL Responses
Boosting Immunity Against Immunosuppressive Infections
Evolutionary Aspects of Immunity
References
Index
ISBN:9780387687339
Series:e-books
Series:SpringerLink (Online service)
Series:Interdisciplinary Applied Mathematics, 0939-6047 : v32
Series:Mathematics and Statistics (Springer-11649)
Keywords: Mathematics , Immunology , Cytology , Ecology , Evolution (Biology) , Biology Mathematics
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Call number:SPRINGER-2006-9783540336549:ONLINE Show nearby items on shelf
Title:The Thermodynamic Machinery of Life [electronic resource]
Author(s): Michal Kurzynski
Date:2006
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Living organisms are open thermodynamic systems whose functional structure has developed and been kinetically frozen during the historical process of biological evolution. A thermodynamics of both nonequilibrium and complexsystems is needed for their description. In this book, the foundations of such a thermodynamics are presented. Biological processes at the cellular level are considered as coupled chemical reactions and transport processes acrossinternal and the cytoplasmic membrane. All these proc esses are catalyzed by specific enzymes hence the kinetics of enzymatic catalysis and its control are described here in detail. The coupling of several processes through a commonenzyme is considered in the context of free energy or signal transduction. Sp ecial attention is paid to evidence for a rich stochastic internal dynamics of native proteins and its possible role in the control of enzyme activity and inthe action of biological molecular machines
Note:Springer eBooks
Contents:Introduction: Biophysics
The Physics of Animate Matter or an Experimental Tool of Biology?
Statistical Description of Matter
Thermodynamic State
Structure and Physiology of Biological Cell
Chemical Reactions
Enzymatic Catalysis
Biological Free Energy Transduction
Applicability Limits of Thermodynamics
ISBN:9783540336549
Series:e-books
Series:SpringerLink (Online service)
Series:The Frontiers Collection, 1612-3018
Series:Physics and Astronomy (Springer-11651)
Keywords: Chemistry, Organic , Biochemistry , Cytology , Thermodynamics , Biomedical engineering
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Call number:SPRINGER-2006-9783540326670:ONLINE Show nearby items on shelf
Title:Life: An Introduction to Complex Systems Biology [electronic resource]
Author(s): Kunihiko Kaneko
Date:2006
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:What is life? Has molecular biology given us a satisfactory answer to this question? And if not, why, and how to carry on from there? This book examines life not from the reductionist point of view, but rather asks the question:what are the universal properties of living systems and how can one construct from there a phenomenological theory of life that leads naturally to complex processes such as reproductive cellular systems, evolution and differentiation?The presentation has been deliberately kept fairly non-technical so as to address a broad spectrum of students and researchers from the natural sciences and informatics
Note:Springer eBooks
Contents:From the contents 1 Introduction
Problems in Molecular Biology
2 Constructive Biology
3 Basic Concepts in Dynamical Systems and Statistical Physics for Biology
4 The Origin of Hededity and Bioinformation
5 Origin of a Cell with Recursive Production and Evolvability
6 Universal Statistical Properties of a Cell with Recursive Production
7 Cell Differentiation and Development I
8 Cell Differentiation and Development II: Stem Cells
9 Pattern Formation and the Origin of Positional Information
10 The Evolution of Diversity
11 Remarks on Other Biological Problems from t
ISBN:9783540326670
Series:e-books
Series:SpringerLink (Online service)
Series:Understanding Complex Systems, 1860-0832
Series:Physics and Astronomy (Springer-11651)
Keywords: Artificial intelligence , Mathematics , Biomedical engineering , Engineering
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Call number:SPRINGER-2006-9783540324157:ONLINE Show nearby items on shelf
Title:Tutorials in Mathematical Biosciences III [electronic resource] : Cell Cycle, Proliferation, and Cancer
Author(s): Avner Friedman
Date:2006
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:This volume introduces some basic mathematical models for cell cycle, proliferation, cancer, and cancer therapy. Chapter 1 gives an overview of the modeling of the cell division cycle. Chapter 2 describes how tumor secretesgrowth factors to form new blood vessels in its vicinity, which provide it with nutrients it needs in order to grow. Chapter 3 explores the process that enables the tumor to invade the neighboring tissue. Chapter 4 models theinteraction between a tumor and the immune system. Chapte r 5 is concerned with chemotherapy it uses concepts from control theory to minimize obstacles arising from drug resistance and from cell cycle dynamics. Finally, Chapter 6reviews mathematical results for various cancer models
Note:Springer eBooks
Contents:Modeling the Cell Division Cycle (B. Aguda)
Angiogenesis
A Biochemical/Mathematical Prospective (H. A. Levine and M. Nilsen
Hamilton)
Spatio
Temporal Models of the uPA System and Tissue Invasion (G. Lolas)
Mathematical Modeling of Spatio
Temporal Phenomena in Tumor Immunology (M. Chaplain and A. Matzavinos)
Control Theory Approach to Cancer Chemotherapy: Benefiting from Phase Dependence and Overcoming Drug Resistance (M. Kimmel and A. Swierniak)
Cancer Models and their Mathematical Analysis (A. Friedman)
ISBN:9783540324157
Series:e-books
Series:SpringerLink (Online service)
Series:Lecture Notes in Mathematics, 0075-8434 : v1872
Series:Mathematics and Statistics (Springer-11649)
Keywords: Mathematics , Differential Equations , Differential equations, partial , Biology Mathematics , Physiology Mathematics , Mathematical optimization
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Call number:SPRINGER-2006-9780387339160:ONLINE Show nearby items on shelf
Title:Power Laws, Scale-Free Networks and Genome Biology [electronic resource]
Author(s): Eugene V Koonin
Yuri I Wolf
Georgy P Karev
Date:2006
Publisher:Boston, MA : Springer US
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Power Laws, Scale-free Networks and Genome Biology deals with crucial aspects of the theoretical foundations of systems biology, namely power law distributions and scale-free networks which have emerged as the hallmarks ofbiological organization in t he post-genomic era. The chapters in the book not only describe the interesting mathematical properties of biological networks but moves beyond phenomenology, toward models of evolution capable of explainingthe emergence of these features. The collection of chapters, contributed by both physicists and biologists, strives to address the problems in this field in a rigorous but not excessively mathematical manner and to represent differentviewpoints, which is crucial in this emerging discipline. Each chapte r includes, in addition to technical descriptions of properties of biological networks and evolutionary models, a more general and accessible introduction to therespective problems. Most chapters emphasize the potential of theoretical systems biology for discovery of new biological phenomena
Note:Springer eBooks
Contents:The Architecture of the Cell: Scaling and Hierarchy in Cellular Networks
Classification of Scale
Free Networks
Wide Spread Occurrence of Power Law Behavior in Genomic Biology
Detection of Topological Patterns in Protein
Binding and Transcription Regulation Networks
The Structure of Metabolic and Protein Interaction Networks: Design, History, or (mere) Chemistry?
Protein
Protein Interaction Networks
The Society of Genes: Networks of Functional Links Between Genes from Comparative Genomics
Emergence of Patterns in Gene Networks
Mathematical Modeling of Genome Evolution: O
ISBN:9780387339160
Series:e-books
Series:SpringerLink (Online service)
Series:Molecular Biology Intelligence Unit
Series:Physics and Astronomy (Springer-11651)
Keywords: Biochemistry , Proteomics , Bioinformatics , Microbial genetics , Biomedical engineering
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Call number:SPRINGER-2006-9780387250977:ONLINE Show nearby items on shelf
Title:The Supercontinuum Laser Source [electronic resource] Fundamentals with Updated References
Author(s): Robert R Alfano
Date:2006
Edition:Second Edition
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Photonics and nonlinear optics are important areas of science, engineering and technology. One of the most important ultrafast nonlinear optical processes is the supercontinuum (SC) the production of intense white lightpulses covering: uv, visible, NIR, MIR, and IR. It is produced using ultrashort laser pulses (ps/fs) to produce the ultrabroad band of frequencies. This book covers the fundamental principles and surveys research of current thinkersand experts in the field with updated references of t he key breakthroughs over the past decade and a half. The application of SC are time-resolved pump-SC probe absorption and excitation spectroscopy for chemistry, biology and physicsfundamental processes optical coherence tomography ultrashort pulse genera tion in femtosecond and attosecond regions frequency clocks phase stabilization optical communication atmospheric science lightning control opticalmedical imaging biological cell imaging and metrology standards
Note:Springer eBooks
ISBN:9780387250977
Series:e-books
Series:SpringerLink (Online service)
Series:Physics and Astronomy (Springer-11651)
Keywords: Laser physics , Quantum optics
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Call number:SPRINGER-2005-9783540314387:ONLINE Show nearby items on shelf
Title:Tutorials in Mathematical Biosciences II [electronic resource] : Mathematical Modeling of Calcium Dynamics and Signal Transduction
Author(s): James Sneyd
Date:2005
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:This book presents a series of models in the general area of cell physiology and signal transduction, with particular attention being paid to intracellular calcium dynamics, and the role played by calcium in a variety of celltypes. Calcium plays a cr ucial role in cell physiology, and the study of its dynamics lends insight into many different cellular processes. In particular, calcium plays a central role in muscular contraction, olfactory transduction andsynaptic communication, three of the topics t o be addressed in detail in this book. In addition to the models, this book also presents much of the underlying physiology, so that readers may learn both the mathematics and the physiologyat the same time, and see how the models are applied to specific biological questions. It is thus neither a mathematics book nor a physiology book, but has features from both sides of the fence. It is intended primarily as a graduatetext or a research reference. However, some parts of the book, particularly the introdu ctory chapters on calcium dynamics will be well within the reach of some undergraduates. It will serve as a concise and up-to-date introduction toall those who wish to learn about the state of calcium dynamics modeling, and how such models are applied to physiological questions
Note:Springer eBooks
Contents:Preface
Introduction
Basic Concept of Ca2+ Signaling in Cells and Tissues (M. J. Sanderson)
Modeling IP
3
Dependent Calcium Dynamics in Non
Excitable Cells (J. Sneyd)
Integrated Calcium Management in Cardiac Myocytes (T. R. Shannon)
Mechanisms and Models of Cardiac Excitation
Contraction Coupling (R. L. Winslow, R. Hinch, J. L. Greenstein)
Mathematical Analysis of the Generation of Force and Motion in Contracting Muscle (E. Pate)
Signal Transduction in Vertebrate Olfactory Receptor Cells (J. Reisert)
Mathematical Models of Synaptic Transmission and Short
Term Plasticity
ISBN:9783540314387
Series:e-books
Series:SpringerLink (Online service)
Series:Lecture Notes in Mathematics, 0075-8434 : v1867
Series:Mathematics and Statistics (Springer-11649)
Keywords: Mathematics , Cytology , Biology Mathematics
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Call number:SPRINGER-2005-9783540270768:ONLINE Show nearby items on shelf
Title:Life As a Matter of Fat [electronic resource] : The Emerging Science of Lipidomics
Author(s): Ole G Mouritsen
Date:2005
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:LIFE - as a Matter of Fat Lipidomics is the science of the fats called lipids. Lipids are as important for life as proteins, sugars, and genes. The present book gives a multi-disciplinary perspective on the physics of life and theparticular role play ed by lipids and the lipid-bilayer component of cell membranes. The book is aimed at undergraduate students and young research workers within physics, chemistry, biochemistry, molecular biology, nutrition, as wellas pharmaceutical and biomedical sciences. The emphasis is on the physical properties of lipid membranes seen as soft and molecularly structured interfaces. By combining and synthesizing insights obtained from a variety of recentstudies, an attempt is made to clarify what membrane structure is an d how it can be quantitatively described. Furthermore, it is shown how biological function mediated by membranes is controlled by lipid membrane structure andorganization on length scales ranging from the size of the individual molecule, across molecular assemblies of proteins and lipid domains in the range of nanometers, to the size of whole cells. Applications of lipids in nano-technologyand biomedicine are also described. The Emerging Science of Lipidomics We have just witnessed a scientific revolution at the end of the 20th century that took us through the genomics era with a focus on sequencing genes and mappinggene products. We are now in the middle of the proteomics era where the multitude of proteins that are encoded in the genes are identified an d their functions are unveiled. In front of us we have a new era recognizing the role oflipids. The science of lipidomics is emerging. Lipidomics involves a quantitative experimental and theoretical study of, e.g. lipid and membrane self-assembly, lipid-p rotein interactions, lipid-gene interactions, and the biophysicalproperties of lipid structure, function, and dynamics
Note:Springer eBooks
Contents:Prologue: Lipidomics
a Science Beyond Stamp Collection
Life From Molecules
Head and Tail
Oil and Water
Lipids Speak the Language of Curvature
A Matter of Softness
Soft Shells Shape up
Biological Membranes
Models and Fashion
Lipids in Bilayers
a Stress
Full and Busy Life
The More We are Together
Lipids in Flatland
Social Lipids
Lively Lipids Provide For Function
Proteins a Lipid Mattresses
Cholesterol on the Scene
Lipids in Charge
Being Smart
a Fishy Matter of Fat
Liquor and Drugs
As a Matter of Fat
Lipid Eaters
Powerful and
ISBN:9783540270768
Series:e-books
Series:SpringerLink (Online service)
Series:The Frontiers Collection, 1612-3018
Series:Physics and Astronomy (Springer-11651)
Keywords: Food science , Polymers , Biochemistry , Soft condensed matter , Biomedical engineering , Surfaces (Physics)
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Call number:SPRINGER-2005-9780387293622:ONLINE Show nearby items on shelf
Title:Bioinformatics and Computational Biology Solutions Using R and Bioconductor [electronic resource]
Author(s): Robert Gentleman
Vincent J Carey
Wolfgang Huber
Rafael A Irizarry
Sandrine Dudoit
Date:2005
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Bioconductor is a widely used open source and open development software project for the analysis and comprehension of data arising from high-throughput experimentation in genomics and molecular biology. Bioconductor is rooted inthe open source statis tical computing environment R. This volume's coverage is broad and ranges across most of the key capabilities of the Bioconductor project, including importation and preprocessing of high-throughput data frommicroarray, proteomic, and flow cytometry platfo rms curation and delivery of biological metadata for use in statistical modeling and interpretation statistical analysis of high-throughput data, including machine learning andvisualization, modeling and visualization of graphs and networks. The developer s of the software, who are in many cases leading academic researchers, jointly authored chapters. All methods are illustrated with publicly available data,and a major section of the book is devoted to exposition of fully worked case studies. This book is more than a static collection of descriptive text, figures, and code examples that were run by the authors to produce the text it is adynamic document. Code underlying all of the computations that are shown is made available on a companion website, and re aders can reproduce every number, figure, and table on their own computers. Robert Gentleman is Head of theProgram in Computational Biology at the Fred Hutchinson Cancer Research Center in Seattle. He is one of the two authors of the original R system and a leading member of the R core team. Vincent Carey is Associate Professor of Medicine(Biostatistics), Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School. Gentleman and Carey are co-founders of the Bioconductor project. Wolfgang Hub er is Group Leader in the European Molecular Biology Laboratory atthe European Bioinformatics Institute in Cambridge. He has made influential contributions to the error modeling of microarray data. Raf
Note:Springer eBooks
Contents:Preprocessing data from genomic experiments
Preprocessing Overview
Preprocessing High
density Oligonucleotide Arrays
Quality Assessment of Affymetrix GeneChip Data
Preprocessing Two
Color Spotted Arrays
Cell
Based Assays
SELDI
TOF Mass Spectrometry Protein Data
Meta
data: biological annotation and visualization
Meta
data Resources and Tools in Bioconductor
Querying On
line Resources
Interactive Outputs
Visualizing Data
Statistical analysis for genomic experiments
Analysis Overview
Distance Measures in DNA Microarray Data Analysis
Cluster Analysis of
ISBN:9780387293622
Series:e-books
Series:SpringerLink (Online service)
Series:Statistics for Biology and Health, 1431-8776
Series:Mathematics and Statistics (Springer-11649)
Keywords: Statistics , Bioinformatics , Animal genetics
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Call number:SPRINGER-2005-9780387274249:ONLINE Show nearby items on shelf
Title:Pumps, Transporters, and Ion Channels [electronic resource] : Studies on Their Structure, Function, and Cell Biology
Author(s): Francisco V Seplveda
Francisco Bezanilla
Date:2005
Publisher:Boston, MA : Springer US
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Springer eBooks
Contents:From the contents: Channels and Pumps Early in Evolution The Possible Role of Aquaporin 0 in Lens Physiology
Central Role of the Ca2+i Regulatory Site in Ionic and Metabolic Modulation of Na+/Ca2+ Exchanger in Dialyzed Squid Axons
Calcium Dependence of Calcium Release Channels (Ryanodine Receptors) from Skeletal and Cardiac Muscle
Modulation of Ryanodine Receptor Channels from Rat Brain Cortex in Lipid Bilayers
Exocytic Pathway Check Points for Functional Potassium Channels in the Plasma Membrane
C
Termini Region Shared by 2A, 1B, and 3 Subunits Confer Prepulse Facilit
ISBN:9780387274249
Series:e-books
Series:SpringerLink (Online service)
Series:Series of the Centro de Estudios Cientficos, 1571-571X
Series:Physics and Astronomy (Springer-11651)
Keywords: Molecular structure , Plasma (Ionized gases) , Superconductivity , Biomedical engineering
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Call number:SPRINGER-2005-9780387260150:ONLINE Show nearby items on shelf
Title:Molecular and Cellular Signaling [electronic resource]
Author(s): Martin Beckerman
Date:2005
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:A small number of signaling pathways, no more than a dozen or so, form a control layer that is responsible for all signaling in and between cells of the human body. The signaling proteins belonging to the control layer determinewhat kinds of cells ar e made during development and how they function during adult life. Malfunctions in the proteins belonging to the control layer are responsible for a host of human diseases ranging from neurological disorders tocancers. Most drugs target components in the control layer, and difficulties in drug design are intimately related to the architecture of the control layer. Molecular and Cellular Signaling provides an introduction to molecular andcellular signaling in biological systems with an emphasis on the unde rlying physical principles. The text is aimed at upper-level undergraduates, graduate students and individuals in medicine and pharmacology interested in broadeningtheir understanding of how cells regulate and coordinate their core activities and how dise ases arise when these regulatory systems malfunction, as well as those in chemistry, physics and computer science interested in pursuing careersin biological and medical physics, bioinformatics and systems biology. To that end, the book includes backgroun d information and review sections, and chapters on signaling in the immune, endocrine (hormonal) and nervous systems. It haschapters on cancer, apoptosis and gene regulation, and contains chapters on bacteria and viruses. In those chapters not specificall y devoted to pathogens, connections between diseases, drugs and signaling are made. Each chapter alsofeatures a problem set to facilitate further discussion and understanding. About the Author: Martin Beckerman, Ph.D. is Senior Scientist at the Center for Martin Beckerman, PhD, is a senior research scientist at the Department ofEnergy/National Nuclear Security Administrations Y-12 National Security Complex in Oak Ridge, TN. Prior to assuming his curre
Note:Springer eBooks
Contents:1. Introduction
2. The Control Layer
3. Exploring Protein Structure and Function
4. Macromolecular Forces
5. Protein Folding and Binding
6. Stress and Pheromone Responses in Yeast
7. Two
Component Signaling Systems
8. Organization of Signal Complexes by Lipids, Calcium and Cyclic Amp
9. Signaling by Cells of the Immune System
10. Cell Adhesion and Motility
11. Signaling in the Endocrine System
12. Signaling in the Endocrine and Nervous System through GPCRs
13. Cell Fate and Polarity
14.Cancer
15. Apoptosis
16. Gene Regulation in Eukaryotes
17. Ce
ISBN:9780387260150
Series:e-books
Series:SpringerLink (Online service)
Series:Biological and Medical Physics, Biomedical Engineering, 1618-7210
Series:Physics and Astronomy (Springer-11651)
Keywords: Medicine , Biochemistry , Cytology , Biomedical engineering
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Call number:SPRINGER-2004-9783642186875:ONLINE Show nearby items on shelf
Title:Life Sciences and Radiation Accomplishments and Future Directions
Author(s):
Date:2004
Size:1 online resource (285 p.)
Note:10.1007/978-3-642-18687-5
Contents:Introductory Remarks: On the State of Radiation Research -- Cellular Responses, Genomic Stability -- Cellular Responses to DNA Damage — a Personal Account -- Prospects for Research in Radiation Biology -- Cellular and Molecular
Aspects of the Anti-inflammatory Action of Low Dose Ionizing Irradiation -- The Network of Radiation Responses and Genomic Stability -- Topological Factors in Radiation Biology -- Signalling -- Molecular Radiation Biology -
Perspectives for the Future -- P53 Stabilization and the Role of Radiation-Induced Signalling -- Cytogenetics -- Molecular Genetic Mechanisms of Radiocarcinogenesis and Predictive Markers for Radioresistance in Tumors — Present Work
and Future Perspectives — -- FISH and CHIPs: Colorful Clues to Radiation-Induced Chromosomal Instability -- Carcinogenesis, Radiation Protection -- Recombination and Radiation-Induced Cancer. Mechanisms and Genetic Testing --
UV-Radiation Biology as Part of Cancer Research -- Contribution of Radiation Research to Human Space Exploration: Approaches to mitigate Radiation Health Risk in Spaceflight -- Repair -- Radiation Damage and Human Cells: You have to
know one to understand the other -- Different Means to an End: DNA Double-Strand Break Repair -- Impact of Physical Developments -- Electrostatistics of DNA Complexes -- Future Radiobiology at Accelerators: From Heavy Ion Therapy to
Basic Research -- Targeting Radiation at the Subcellular, Cellular and Tissue Levels: Future Strategies -- The PTB — a Competent and Reliable Partner for Research and Development Projects in the Field of Ionizing Radiation -- General
Issues -- Life Sciences and Radiation Research - Examples from the Past -- Need and Importance of Further Research in the Field of Radiation -- Reflections on the Acceptability of the Use of Ionizing Radiation to German Society --
Janus Face of Radiation Biology and Science for the Future -- Postscript: Thoughts on the Future of Radiation Research and its Impact on Life Sciences
ISBN:9783642186875
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Physics , Radiotherapy , Cell biology , Biophysics , Biological physics , Physics , Biophysics and Biological Physics , Radiotherapy , Cell Biology
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Call number:SPRINGER-2004-9783034878951:ONLINE Show nearby items on shelf
Title:Function and Regulation of Cellular Systems
Author(s):
Date:2004
Size:1 online resource (23 p.)
Note:10.1007/978-3-0348-7895-1
Contents:to Part I -- A Functional Dynamics Approach to Modelling of Glycolysis -- Temperature-Compensation in Biological Clocks:Models and Experiments -- Metabolic Control Analysis of the ATPase Network in Contracting Muscle:Regulation of
Contractile Function and ATP Free Energy Potential -- En Route for Systems Biology: In Silico Pathway Analysis and Metabolite Profiling -- to Part II -- Presynaptic Calcium Dynamics of Neurons in Answer to VariousStimulation Protocols
-- Mathematical Modeling of Signaling Cascades: Principles and Future Prospects -- Collective Behavior of Membrane Channels: Electro-physiological Studies on Gap Junctions -- Modelling of Periodic Intercellular Ca2+ Waves -- Travelling
Waves as a Mechanism of Pattern Generation in Discrete Cell Lattices -- Design and Operation: Keys to Understanding Biological Systems -- to Part III -- Biopolymer Dynamics -- Micromechanics of Molecular Motors: Experiments and Theory
-- The Role of Osteocalcin in the Remodeling of Biomimetic Hydroxyapatite-Collagen Materials for Bone Replacement -- Cell Shape Normalization of Normal and Haploinsufficient NF1-Melanocytes by Micro-Structured Substrate Interaction --
Quantification of Shear Stress-Induced Cell Migration in Endothelial Cultures -- to Part IV -- Constructive and Dynamical Systems Approach to Life -- Coherent Dynamics in Networks of Single Protein Molecules -- Gene Regulatory
Networks: A Discrete Model of Dynamics and Topological Evolution -- Evolutionary Reconstruction of Networks -- Modelling Simple Biochemical Networks -- On the Evolution of Information in the Constituents of Regulatory Gene Networks --
to Part V -- Biological Relevance of Tissue Liquidity and Viscoelasticity -- Reinforcement of Cytoskeleton-Matrix Bonds and Tensiotaxis: A Cell-Based Model -- Simulation of Haematopoietic Stem Cell Organisation Using a Single Cell
Based Model Approach -- Pattern Formation in an Interacting Cell System: Rippling in Myxobacterial Aggregates -- to Part VI -- Molecular and Cellular Analysis of De Novo Pattern Formation in Hydra -- The Small Freshwater Polyp Hydra as
a Model for Axis Formationin Higher Organisms -- Cell Migration, Cell Fate and Pattern Formation During Head Development in Lungfishes and Amphibians -- Cell-Based Modelling of Tissues -- to Part VII -- Cell-Based Models of Avascular
Tumor Growth -- Solid Tumor Invasion: The Importance of Cell Adhesion -- Interrelationship of Tumor and Immune System -- Nonlinear Dynamics and Statistical Physics of Models for the Immune System -- Stochastic Model of Influenza Virus
Fusion -- Spatio-Temporal Aspects of a Dynamical Disease: Waves of Spreading Depression -- List of contributors -- Color Plates
ISBN:9783034878951
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Mathematics , Computer simulation , Bioinformatics , Computational biology , System theory , Biomathematics , Mathematics , Mathematical and Computational Biology , Simulation and Modeling , Systems Theory, Control , Computer Appl. in Life Sciences , Physiological, Cellular and Medical Topics
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Call number:SPRINGER-2003-9784431659587:ONLINE Show nearby items on shelf
Title:Morphogenesis and Pattern Formation in Biological Systems Experiments and Models
Author(s):
Date:2003
Size:1 online resource (32 p.)
Note:10.1007/978-4-431-65958-7
Contents:Models for Morphogenesis and Pattern Formation -- Pattern Forming Reactions and the Generation of Primary Embryonic Axes -- Spatial Pattern Formation and Morphogenesis in Development: Recent Progress for Two Model Systems -- Alan
Turing and “The Chemical Basis of Morphogenesis” -- On the Stochastic Geometry of Growth -- The Moving Grid Finite Element Method Applied to Biological Problems -- Morphogenesis and Pattern Formation in Animals -- Regulation of Pattern
Formation by the Interaction between Growth Factors and Proteoglycans -- Changing Roles of Homeotic Gene Functions in Arthropod Limb Development -- Variation, Adaptation and Developmental Constraints in the Mimetic Butterfly Papilio
dardanus -- Formation of New Organizing Regions by Cooperation of hedgehog, wingless, and dpp in Regeneration of the Insect Leg a Verification of the Boundary Model -- The Heterotopic Shift in Developmental Patterns and Evolution of
the Jaw in Vertebrates -- Morphogenesis and Pattern Formation in Plants -- The Development of Cell Pattern in the Arabidopsis Root Epidermis -- Pattern Formation during Dicotyledonous Plant Embryogenesis -- Regulation of Inflorescence
Architecture and Organ Shape by the ERECTA Gene in Arabidopsis -- Axis-dependent Regulation of Lateral Organ Development in Plants -- Formation of a Symmetric Flat Leaf Lamina in Arabidopsis -- Morphogenesis and Pattern Formation
Viewed from the Behaviour of Individual Cells -- Pattern Formation by Cell Movement in Closely-Packed Tissues -- Positioning of Cells at their Intrinsic Sites in Multicellular Organisms -- Spatial Pattern and Structure Formation in
Ecological Systems -- Biological Invasion into Periodically Fragmented Environments: A Diffusion-Reaction Model -- Spatial Pattern Formation in Plant Communities -- The Mode of Competition and Spatial Pattern Formation in Plant
Communities -- Formation of a Structure of Exponentially Forking Branches with a Steady-state Amount of Current-year Shoots in a Hardwood Tree Crown -- Spatio-Temporal Pattern Formation in Epidemiology -- Patterns in Epidemiology of
Sexually Transmitted Diseases in Human Populations -- Backward Bifurcation in a Model for Vector Transmitted Disease -- Morphogenesis and Pattern Formation in Medicine -- Mathematical Modelling of Solid Tumour Growth: Applications of
Pre-pattern Formation -- The Formation of Branching Systems in Human Organs -- Computer Simulation on Morphogenesis of Colonic Neoplasia -- The Effects of Cell Adhesion on Solid Tumour Geometry -- Diversity of Biological Patterns in
the Fossil Record and Their Meaning in Morphological Evolution -- Pattern Formation and Function in Palaeobiology -- Why do Univalve Shells of Gastropods Coil so Tightly? A Head-Foot Guidance Model of Shell Growth and its Implication
on Developmental Constraints -- Computer Modeling of Microscopic Features of Molluscan Shells -- How Anomalocaris Swam in the Cambrian Sea A Theoretical Study Based on Hydrodynamics -- Morphology and Function of Cuticular Terraces in
Stomatopoda (Crustacea) and Mantodea (Insecta)
ISBN:9784431659587
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Mathematics , Infectious diseases , Oncology , Biodiversity , Evolutionary biology , Biomathematics , Mathematics , Mathematical and Computational Biology , Infectious Diseases , Oncology , Biodiversity , Evolutionary Biology
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Call number:SPRINGER-2003-9783540448785:ONLINE Show nearby items on shelf
Title:Understanding Calcium Dynamics Experiments and Theory
Author(s):
Date:2003
Size:1 online resource (300 p.)
Note:10.1007/b11586
Contents:Regulation of IP3 Receptors by IP3 and CA2+ -- The Endoplasmic Reticulum: a Central Player in Cell Signalling and Protein Synthesis -- Mitochondrial and ER Calcium Uptake and Release Fluxes and Their Interplay in Intact Nerve Cells --
Global and Local Regulation of Neuronal Differentiation By Calcium Transients -- Role of NAADP in Coordinating Spatiotemporal Aspects of Calcium Signalling -- Models of Cardiac CA2+- Induced CA 2+ Release and Ca2+ Sparks -- From Simple
to Complex Ca2+ Oscillations: Regulatory Mechanisms and Theoretical Models -- Information Processing in Calcium Signal Transduction -- Modeling Calcium Waves -- Mathematical Modeling and High Resolution Fluorescence Imaging for
Studying Calcium Regulation -- Langevin Modeling of Intracellular Calcium Dynamics -- Building a Wave - Models of the Puff-to-Wave Transition
ISBN:9783540448785
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:Lecture Notes in Physics: 623
Keywords: Physics , Physical chemistry , Medical biochemistry , Biochemistry , Cell biology , Biophysics , Biological physics , Statistical physics , Dynamical systems , Physics , Biophysics and Biological Physics , Physical Chemistry , Medical Biochemistry , Biochemistry, general , Cell Biology , Statistical Physics, Dynamical Systems and Complexity
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Call number:SPRINGER-2003-9783034880435:ONLINE Show nearby items on shelf
Title:Polymer and Cell Dynamics Multiscale Modeling and Numerical Simulations
Author(s):
Date:2003
Size:1 online resource (308 p.)
Note:10.1007/978-3-0348-8043-5
Contents:to Part I -- Molecular Dynamics Studies of Micelle and Capsid Self-assembly -- A Functional Study on Saposin B and C Using Experimentally Validated Models -- A Review of the Morph Server and the Macromolecular Motions Database: A
Standardized System for Analyzing and Visualizing Macromolecular Motions in a Database Framework -- to Part II -- Brownian Dynamics of Flexible Polymers in Flow -- A Microscopic Model for the Dynamics of Actin Filaments in Motility
Assays and Its Numerical Simulation -- Multiparticle Modeling of Actin-Myosin Networks: From Molecular Interactions to Cell Motility -- Analysis of Cell Motility Combining Cytomechanical Model Simulations and an Optical Flow Method --
Micropipet Aspiration of the Human Neutrophil -- Physical-object-oriented 3D Simulations of Cell Deformations and Migration -- to Part III -- Computational Modeling of Blood Clotting: Coagulation and Three-dimensional Platelet
Aggregation -- Space-and Time-resolved Simulations of Processes in Biofilm Systems on a Microscale -- On Selected Individual-based Approaches to the Dynamics in Multicellular Systems -- Individual-based Models of Cohort Migration in
Cell Cultures -- Interactive Movement, Aggregation, and Swarm Dynamics -- A Discrete-cell Model of Tissue-equivalent Compaction -- A Hybrid Discrete-continuum Technique for Individual-based Migration Models -- Application of the Hybrid
Discrete-continuum Technique -- List of contributors and workshop participants
ISBN:9783034880435
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Mathematics , Computer simulation , Biomathematics , Mathematics , Mathematical and Computational Biology , Simulation and Modeling
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Call number:SPRINGER-2003-9780387216409:ONLINE Show nearby items on shelf
Title:Nonlinear Dynamics in Physiology and Medicine
Author(s):
Date:2003
Size:1 online resource (436 p.)
Note:10.1007/978-0-387-21640-9
Contents:1 Theoretical Approaches in Physiology -- 2 Introduction to Dynamics in Nonlinear Difference and Differential Equations -- 3 Bifurcations Involving Fixed Points and Limit Cycles in Biological Systems -- 4 Dynamics of Excitable Cells
-- 5 Resetting and Entraining Biological Rhythms -- 6 Effects of Noise on Nonlinear Dynamics -- 7 Reentry in Excitable Media -- 8 Cell Replication and Control -- 9 Pupil Light Reflex: Delays and Oscillations -- 10 Data Analysis and
Mathematical Modeling of Human Tremor -- A An Introduction to XPP -- Michael C. Mackey -- A.1 ODE Files -- A.2 Starting and Quitting XPP -- A.3 Time Series -- A.4 Numerics -- A.5 Graphic Tricks -- A.5.1 Axis -- A.5.2 Multiplotting --
A.5.3 Erasing -- A.5.4 Printing the Figures -- A.6 Examining the Numbers -- A.7 Changing the Initial Condition -- A.8 Finding the Fixed Points and Their Stability -- A.9 Drawing Nullclines and Direction Field -- A.10 Changing the
Parameters -- A.11 Auto -- A.11.1 Bifurcation Diagram -- A.11.2 Scrolling Through the Points on the Bifurcation Diagram -- A.12 Saving Auto Diagrams -- B An Introduction to Matlab -- Michèle S. Titcombe and Caroline Haurie -- R.1
Starting and Quitting Matlab -- B.2 Vectors and Matrices -- B 2 1 Creating Matrices and Vectors -- .B.3 Suppressing Output to the Screen (the Semicolon!) -- B.4 Operations on Matrices -- B.5 Programs (M-Files) -- B.5.1 Script Files --
B.5.2 Function Files -- B.6 The Help Command -- B.7 Loops -- B.8 Plotting -- B.8.1 Examples -- B.8.2 Clearing Figures and Opening New Figures -- B.8.3 Symbols and Colors for Lines and Points -- B.9 Loading Data -- B.9.1 Examples --
B.10 Saving Your Work -- C Time Series Analysis -- Roderick Edwards and Michèle S. Titcombe -- C.1 The Distribution of Data Points -- C.2 Linear Processes -- C.3 Fourier Analysis
ISBN:9780387216409
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:Interdisciplinary Applied Mathematics: 25
Keywords: Mathematics , Neurosciences , Neurobiology , Biomathematics , Biophysics , Biological physics , Mathematics , Mathematical and Computational Biology , Neurosciences , Neurobiology , Biophysics and Biological Physics
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Call number:SPRINGER-2002-9783034881197:ONLINE Show nearby items on shelf
Title:Fractals in Biology and Medicine
Author(s):
Date:2002
Size:1 online resource (362 p.)
Note:10.1007/978-3-0348-8119-7
Contents:Fractal Design of Biological Structures and Functions -- Pattern Complexity in Organogenesis and Carcinogenesis -- Fractal Structure of Space and Time is Necessary for the Emergence of Self-Organization, Connectivity, and Collectivity
in Cellular System -- Diffusion Screening, Acinus Size and Optimal Design of Mammalian Lungs -- Three-Dimensional Model of the Human Airway Tree Based on a Fractal Branching Algorithm -- Fractal Dimension, Form and Shape Factors for
the Quantification of Nuclear Signature Profiles -- Fractal Signature Vectors and Lacunarity Class Distance Matrices to Extract New Adaptive Texture Features from Cell Nuclei -- Morphofractal Reorganization of Plasma Membrane and
Nuclear Components during the Apoptosis of Breast Cancer Cells -- Fractal Analysis of Chromatin during Apoptosis -- Fractal Structures in Tumours and Diseases -- Asymptotic Fractals, Geostatistics and Hurst Parameter Heterogeneity and
Histological Grades in Breast Cancer -- The Fractal Dimension of the Inner Surface of Neoplastic Mammary Ducts in Mammary Fibroadenomas and Mammary Carcinomas of Dog and Cat: Preliminary Data -- Classification of Prostatic Cancer Using
Artificial Neural Networks -- Fractal Dimension Exponent for Quantitative Evaluation of Liver Extracellular Matrix in Biopsy Specimens -- Two-Dimensional Fractal Geometric Analysis of Bone Marrow Tissue in Hyperplasia, Refractory
Anemia and Acute Leukemia -- Color-Based Method for Fractal Dimension Estimation of Pigmented Skin Lesion Contour -- The EEG Signal in Hepatic Encephalopathy: from a Time-Domain Statistical Analysis toward Fractional Brownian Processes
-- A Fractal Approach of Pathological Voices -- A Vowel Fractal Dimension Study -- Bone Architecture Measured by Fractal Dimension and Connectivity Indices is More Precociously Altered than Mineral Content in the Orchidectomized Rat --
Texture Analyses of X-Ray Micrographs (Fractal Geometry and Run Length) are Better Predictors of Bone Loss than Mineral Content in a Rat Model of Localized Disuse Osteopenia -- Fractal Scaling of Heartrate Dynamics in Health and
Disease -- Information States in Cardiac Rhythm -- Some Remarks on the Fractal Dimension Applications in -- Nuclear Medicine -- Organization and Evolution of Living Systems -- Fractional Calculus and Memory in Biophysical Time Series
-- The Biological Meanings of DNA Correlations -- On the Fractal Structure of Evolutionary Trees -- Metabolic Hypercycles, Universality and Fractals in Biological Evolution -- The Universal Dynamic Complexity as Extended Dynamic
Fractality: Causally Complete Understanding of Living Systems Emergence and Operation -- Modelling -- A Headful of T4 Coliphage DNA: Dynamical Modelling -- On Lacunarity Analysis -- The Fractal Dimension of the Coastline as a
Determinant of Western Leadership in Science and Technology -- A Fractional Calculus Approach to Adsorbate Dynamics in -- Nanoporous Materials -- Complex Aspects of the Riemann Hypothesis: a Computational -- Approach -- Fractals in
Architecture: Some Examples
ISBN:9783034881197
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Mathematics , Health informatics , Biochemistry , Biomathematics , Mathematics , Mathematical and Computational Biology , Health Informatics , Biochemistry, general
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Call number:SPRINGER-2002-9780387224596:ONLINE Show nearby items on shelf
Title:Computational Cell Biology
Author(s):
Date:2002
Size:1 online resource (468 p.)
Note:10.1007/b97701
Contents:Introductory Course -- Dynamic Phenomena in Cells -- Voltage Gated Ionic Currents -- Transporters and Pumps -- Fast and Slow Time Scales -- Whole—Cell Models -- Intercellular Communication -- Advanced Material -- Spatial Modeling --
Modeling Intracellular Calcium Waves and Sparks -- Biochemical Oscillations -- Cell Cycle Controls -- Modeling the Stochastic Gating of Ion Channels -- Molecular Motors: Theory -- Molecular Motors: Examples
ISBN:9780387224596
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:Interdisciplinary Applied Mathematics: 20
Keywords: Life sciences , Cell biology , Neurobiology , Applied mathematics , Engineering mathematics , Biomathematics , Biophysics , Biological physics , Life Sciences , Cell Biology , Mathematical and Computational Biology , Applications of Mathematics , Neurobiology , Biophysics and Biological Physics
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Call number:SPRINGER-2002-9780387216393:ONLINE Show nearby items on shelf
Title:Branching Processes in Biology
Author(s): Marek Kimmel
Date:2002
Size:1 online resource (232 p.)
Note:10.1007/b97371
Contents:Motivating Examples and Other Preliminaries -- Biological Background -- The Galton-Watson Process -- The Age-Dependent Process: The Markov Case -- The Bellman-Harris Process -- Multitype Processes -- Branching Processes with
Infinitely Many Types -- References
ISBN:9780387216393
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:Interdisciplinary Applied Mathematics: 19
Keywords: Mathematics , Bioinformatics , Cell biology , Probabilities , Biomathematics , Statistics , Mathematics , Mathematical and Computational Biology , Probability Theory and Stochastic Processes , Statistics for Life Sciences, Medicine, Health Sciences , Bioinformatics , Cell Biology
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Call number:SPRINGER-2002-9780387215716:ONLINE Show nearby items on shelf
Title:Modeling and Simulation in Medicine and the Life Sciences
Author(s): Frank C Hoppensteadt
Date:2002
Edition:Second Edition
Size:1 online resource (355 p.)
Note:10.1007/978-0-387-21571-6
Contents:1 The Heart and Circulation -- 1.1 Plan of the Circulation -- 1.2 Volume, Flow, and Pressure -- 1.3 Resistance and Compliance Vessels -- 1.4 The Heart as a Pair of Pumps -- 1.5 Mathematical Model of the Uncontrolled Circulation -- 1.6
Balancing the Two Sides of the Heart and the Two Circulations -- 1.7 The Need for External Circulatory Control Mechanisms -- 1.8 Neural Control: The Baroreceptor Loop -- 1.9 Autoregulation -- 2 Gas Exchange in the Lungs -- 2.1 The
Ideal Gas Law and the Solubility of Gases -- 2.2 The Equations of Gas Transport in One Alveolus -- 2.3 Gas Transport in the Lung -- 2.4 Optimal Gas Transport -- 2.5 Mean Alveolar and Arterial Partial Pressures -- 2.6 Transport of O2 --
2.7 Computer Solution of the Equations for O2 Transport in the Lung -- 2.8 Computing Projects Concerning Oxygen Transport by the Lung -- 2.9 Annotated References -- Exercises -- 3 Control of Cell Volume and Electrical Properties of
Cell Membranes -- 3.1 Osmotic Pressure and the Work of Concentration -- 3.2 A Simple Model of Cell Volume Control -- 3.3 The Movement of Ions Across Cell Membranes -- 3.4 The Interaction of Electrical and Osmotic Effects -- 3.5 The
Hodgkin-Huxley Equations for the Nerve Action Potential -- 3.6 Computer Simulation of the Nerve Action Potential -- 3.7 Suggestions for Computing Projects Concerning the Nerve Impulse -- 3.8 Annotated References -- Exercises -- 4 The
Renal Countercurrent Mechanism -- 4.1 The Nephron -- 4.2 Dynamics of Na+ and H2O: Transport along the Renal Tubules -- 4.3 The Loop of Henle -- 4.4 The Juxtaglomerular Apparatus and the Renin-Angiotensin System -- 4.5 The Distal Tubule
and Collecting Duct: Concentrating and Diluting Modes -- 4.6 Remarks on the Significance of the Juxtaglomerular Apparatus -- 4.7 How Nephrons Do Better Than a Factor of e -- 4.8 Computing Project on the Interacting Nephron Population
Model -- 4.9 Annotated References -- Exercises -- 5 Muscle Mechanics -- 5.1 The Force-Velocity Curve -- 5.2 Crossbridge Dynamics -- 5.3 Computer Simulation of Crossbridge Attachment and Detachment -- 5.4 Suggested Computing Projects on
Crossbridge Dynamics -- 5.5 Annotated References -- Exercises -- 6 Neural Systems -- 6.1 Guttman’s Experiments on Phase Locking -- 6.2 Biological Rhythms -- 6.3 Model Neural Networks -- 6.4 Annotated References -- Exercises -- 7
Population Dynamics -- 7.1 Bacterial Cultures -- 7.2 Age Structures -- 7.3 Microbial Ecology -- 7.4 Nonlinear Reproduction Curves -- 7.5 Controlling Populations -- 7.6 Annotated References -- Exercises -- 8 Genetics -- 8.1 Population
Genetics -- 8.2 Biotechnology -- 8.3 Annotated References -- Exercises -- 9 A Theory of Epidemics -- 9.1 Spread of Infection Within a Family -- 9.2 The Threshold of an Epidemic -- 9.3 Predicting the Severity of an Epidemic -- 9.4
Annotated References -- Exercises -- 10 Patterns of Population Growth and Dispersal -- 10.1 Random Walks and the Process of Diffusion -- 10.2 Bacterial Growth on a Petri Plate -- 10.3 Concluding Remarks -- 10.4 Annotated References --
Exercises -- Appendix A Getting Started with Matrices and Matlab -- Appendix B Background on Random Processes
ISBN:9780387215716
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:Texts in Applied Mathematics: 10
Keywords: Mathematics , Life sciences , Ecology , Applied mathematics , Engineering mathematics , Mathematical models , Biomathematics , Mathematics , Mathematical Modeling and Industrial Mathematics , Applications of Mathematics , Life Sciences, general , Physiological, Cellular and Medical Topics , Mathematical and Computational Biology , Ecology
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Call number:SPRINGER-2001-9783642595424:ONLINE Show nearby items on shelf
Title:Fluorescence Correlation Spectroscopy Theory and Applications
Author(s): Rudolf Rigler
Date:2001
Size:1 online resource (487 p.)
Note:10.1007/978-3-642-59542-4
Contents:1. Introduction -- References -- I FCS in the Analysis of Molecular Interactions -- 2 Fluorescence Correlation Spectroscopy of Flavins and Flavoproteins -- 3 Fluorescence Correlation Spectroscopy in Nucleic Acid Analysis -- 4
Strain-Dependent Fluorescence Correlation Spectroscopy: Proposing a New Measurement for Conformational Fluctuations of Biological Macromolecules -- 5 Applications of FCS to Protein-Ligand Interactions: Comparison with Fluorescence
Polarization -- II FCS at the Cellular Level -- 6 FCS-Analysis of Ligand-Receptor Interactions in Living Cells -- 7 Fluorescence Correlation Microscopy (FCM): Fluorescence Correlation Spectroscopy (FCS) in Cell Biology -- 8 FCS and
Spatial Correlations on Biological Surfaces -- III Applications in Biotechnology, Drug Screening, and DiagnosticsPart 2 FCS at the Cellular Level -- 9 Dual-Color Confocal Fluorescence Spectroscopy and its Application in Biotechnology
-- 10 Nanoparticle Immunoassays: A new Method for Use in Molecular Diagnostics and High Throughput Pharmaceutical Screening based on Fluorescence Correlation Spectroscopy -- 11 Protein Aggregation Associated with Alzheimer and Prion
Diseases -- IV Environmental Analysis and Monitoring -- 12 Application of FCS to the Study of Environmental Systems -- 13 Photophysical Aspects of FCS Measurements -- V New Developments and Trends -- 14 Fluorescence Correlation
Spectroscopy: Genesis, Evolution, Maturation and Prognosis -- 15 ConfoCor 2 The Second Generation of Fluorescence Correlation Microscopes -- 16 Antibunching and Rotational Diffusion in FCS -- 17 Cross-correlation analysis in FCS -- 18
Cross-correlated Flow Analysis in Microstructures -- 19 Introduction to the Theory of Fluorescence Intensity Distribution Analysis -- 20 Photon Counting Histogram Statistics -- 21 High Order Autocorrelation in Fluorescence Correlation
Spectroscopy -- 22 FCS in Single Molecule Analysis
ISBN:9783642595424
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:Springer Series in Chemical Physics: 65
Keywords: Physics , Physical chemistry , Atoms , Solid state physics , Optics , Optoelectronics , Plasmons (Physics) , Spectroscopy , Microscopy , Physics , Atomic, Molecular, Optical and Plasma Physics , Physical Chemistry , Solid State Physics , Spectroscopy and Microscopy , Optics, Optoelectronics, Plasmonics and Optical Devices
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