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SPIRES-BOOKS: FIND KEYWORD LIFE SCIENCES *END*INIT* use /tmp/qspiwww.webspi1/5555.5 QRY 131.225.70.96 . find keyword life sciences ( in books using www Cover
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Call number:9789811033070:ONLINE Show nearby items on shelf
Title:Monte-Carlo Simulation-Based Statistical Modeling
Author(s):
Date:2017
Size:1 online resource (XX, 430 p. 64 illus., 33 illus. in color p.)
Contents:Part 1: Monte-Carlo Techniques -- 1. Overview of Monte-Carlo Techniques -- 2. On Improving the Efficiency of the Monte-Carlo Methods Using Ranked Simulated Approach -- 3. Joint generation of Different Types of Data with Specified
Marginal and Association Structures for Simulation Purposes -- 4. Quantifying the Uncertainty in Optimal Experimental Schemes via Monte-Carlo Simulations -- 5. Normal and Non-normal Data Simulations for the Evaluation of Two-sample
Location Tests -- 6. Understanding dichotomization from Monte-Carlo Simulations -- Part 2: Monte-Carlo Methods in Missing Data -- 7. Hybrid Monte-Carlo in Multiple Missing Data Imputations with Application to a Bone Fracture Data -- 8.
Methods for Handling Incomplete Longitudinal Data due to Missing at Random Dropout -- 9. Applications of Simulation for Missing Data Issues in Longitudinal Clinical Trials -- 10. Application of Markov Chain Monte Carlo Multiple
Imputation Method to Deal with Missing Data From the Mechanism of MNAR in Sensitivity Analysis for a Longitudinal Clinical Trial -- 11. Fully Bayesian Methods for Missing Data under Ignitability Assumption -- Part 3: Monte-Carlo in
Statistical Modellings -- 12. Markov-Chain Monte-Carlo Methods in Statistical modelling -- 13. Monte-Carlo Simulation in Modeling for Hierarchical Linear Mixed Models -- 14. Monte-Carlo Simulation of Correlated Binary Responses -- 15.
Monte Carlo Methods in Financial Modeling -- 16. Bayesian Intensive Computations in Elliptical Models.
ISBN:9789811033070
Series:eBooks
Series:Springer eBooks
Series:Springer 2017 package
Keywords: Statistics , Biostatistics , Statistics , Statistics for Life Sciences, Medicine, Health Sciences , Biostatistics
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Call number:9783319501864:ONLINE Show nearby items on shelf
Title:Statistical Applications for Chemistry, Manufacturing and Controls (CMC) in the Pharmaceutical Industry
Author(s): Richard K Burdick
Date:2017
Size:1 online resource (XI, 379 p. 113 illus., 80 illus. in color p.)
Contents:Chapter 1. Introduction -- Chapter 2. Statistical Methods for CMC Applications -- Chapter 3. Process Design: Stage 1 of the FDA Process Validation Guidance -- Chapter 4. Process Qualification: Stage 2 of the FDA Process Validation
Guidance -- Chapter 5. GMP Monitoring and Continuous Process Verification: Stage 3 of the FDA Process Validation Guidance -- Chapter 6. Analytical Procedures -- Chapter 7. Specifications -- Chapter 8. Stability -- Chapter 9. Analytical
Comparability and Similarity
ISBN:9783319501864
Series:eBooks
Series:Springer eBooks
Series:Springer 2017 package
Keywords: Pharmacy , Statistics , Pharmaceutical technology , Statistics , Statistics for Life Sciences, Medicine, Health Sciences , Pharmaceutical Sciences/Technology , Pharmacy
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Call number:9783319458090:ONLINE Show nearby items on shelf
Title:Statistical Analysis of Proteomics, Metabolomics, and Lipidomics Data Using Mass Spectrometry
Author(s):
Date:2017
Size:1 online resource (VIII, 295 p. 106 illus., 83 illus. in color p.)
Contents:Transformation, normalization and batch effect in the analysis of mass spectrometry data for omics studies -- Automated Alignment of Mass Spectrometry Data Using Functional Geometry -- The analysis of peptide-centric mass spectrometry
data utilizing information about the expected isotope distribution -- Probabilistic and likelihood-based methods for protein identification from MS/MS data -- An MCMC-MRF Algorithm for Incorporating Spatial Information in IMS Data
Processing -- Mass Spectrometry Analysis Using MALDIquant -- Model-based analysis of quantitative proteomics data with data independent acquisition mass spectrometry -- The analysis of human serum albumin proteoforms using
compositional framework -- Variability Assessment of Label-Free LC-MS Experiments for Difference Detection -- Statistical approach for biomarker discovery using label-free LC-MS data - an overview -- Bayesian posterior integration for
classification of mass spectrometry data -- Logistic regression modeling on mass spectrometry data in proteomics case-control discriminant studies -- Robust and confident predictor selection in metabolomics -- On the combination of
omics data for prediction of binary Outcomes -- Statistical analysis of lipidomics data in a case-control study
ISBN:9783319458090
Series:eBooks
Series:Springer eBooks
Series:Springer 2017 package
Keywords: Statistics , Analytical chemistry , Mathematical statistics , Bioinformatics , Biostatistics , Metabolism , Statistics , Statistics for Life Sciences, Medicine, Health Sciences , Biostatistics , Metabolomics , Computational Biology/Bioinformatics , Analytical Chemistry , Probability and Statistics in Computer Science
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Call number:9783319444970:ONLINE Show nearby items on shelf
Title:Mars One The Ultimate Reality TV Show?
Author(s): Erik Seedhouse
Date:2017
Size:1 online resource (XXIII, 174 p. 93 illus., 84 illus. in color p.)
Contents:Acknowledgements -- Dedication -- About the Author -- Acronyms -- Preface -- 1: Mars One: The Concept -- 2: Is this ethical? -- 3: Is any of this legal? -- 4: Selection -- 5: Training -- 6: Medical mission killers -- 7: Technology
feasibility -- 8: Bursting the Mars One life support bubble -- Epilog -- Appendices -- Index
ISBN:9783319444970
Series:eBooks
Series:Springer eBooks
Series:Springer 2017 package
Keywords: Popular works , Project management , Technology , Aerospace engineering , Astronautics , Popular Science , Popular Science in Technology , Aerospace Technology and Astronautics , Space Sciences (including Extraterrestrial Physics, Space Exploration and Astron , Project Management
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Call number:9783319444185:ONLINE Show nearby items on shelf
Title:Space, Time and the Limits of Human Understanding
Author(s):
Date:2017
Size:1 online resource (XXIII, 530 p. 51 illus p.)
Contents:Philosophy: Śrīharṣa on the Indefinability of Time by Jonathan Duquette and Krishnamurti Ramasubramanian -- Why Spacetime Has a Life of its Own by James Robert Brown -- From Time to Time by Nathan Salmon -- Relativity Theory may not
have the last Word on the Nature of Time: Quantum Theory and Probabilism by Nicholas Maxwell -- Space as a Source and as an Object of Knowledge: The Transformation of the Concept of Space in the Post-Kantian Philosophy of Geometry by
Francesca Biagioli -- Space, Time and (how they) Matter by Valia Allori -- The Phenomenology of Space and Time: Husserl, Sartre, Derrida by Hans Herlof Grelland -- Time and Space in Ancient India, Pre­-Philosophical Period by Michael
Witzel and Nataliya Yanchevskaya -- Time in Physics and Time in Awareness by E. C. G. Sudarshan -- Physics: The Future’s Not Ours to See, by Tony Sudbury -- Nature’s Book Keeping System by Gerard ‘t Hooft -- An anomaly in space and
time and the origin of dynamics by Joan A. Vaccaro -- Spacetime and Reality: Facing the Ultimate Judge by Vesselin Petkov -- Hermann Weyl’s Space-Time Geometry and its Impact on Theories of Fundamental Interactions by Norbert Straumann
-- Space, Time, and Adynamical Explanation in the Relational Blockworld by W.M. Stuckey, Michael Silberstein, and Timothy McDevitt -- Matter, Space, Time, and Motion: A Unified Gravitational Perspective by C. S. Unnikrishnan --
Spacetime is Doomed by George Musser -- Mathematics: Geometry and Physical Space by Mary Leng -- The Geometry of Manifolds and the Perception of Space by Raymond O. Wells, Jr -- Topos Theoretic Approach to Space and Time by Goro C.
Kato -- Paradox? The Mathematics of Space-Time and the Limits of Human Understanding by Paul Ernest -- General Relativity, Time, and Determinism by James Isenberg -- “Now” has an infinitesimal positive duration by Reuben Hersh -- The
Fundamental Problem of Dynamics by Julian Barbour -- What’s wrong with the Platonic ideal of space and time? by Lorenzo Sadun -- Biology/Cognitive Science: Syntactic Space by Rajesh Kasturirangan -- Time measurement in living systems:
Human understanding and health implications by L Abhilash and Vijay Kumar Sharma -- The cellular space-the space of life by Pier Luigi Luisi -- The consciousness of space, the space of consciousness by Mauro Bergonzi and Pier Luigi
Luisi -- Time and Suffering (False metaphors, (de)synchronous times, and internal dynamics) by Norman Sieroka -- Evolutionary Time and the Creation of the Space of Life by Randall E. Auxier -- Computer Science: A computational
mathematics view of space, time and complexity by David H. Bailey and Jonathan M. Borwein -- The Black Hole in Mathematics by A. K. Dewdney -- Gödel’s Ontological Dreams by Gary Mar -- ‘Photographing the Footsteps of Time’: Space and
Time in Charles Babbage’s Calculating Engines by Doron Swade -- Gödel incompleteness and the empirical sciences by N. C. A. da Costa and F. A. Doria -- Miscellaneous: The Novel and the Map: Spatiotemporal Form and Discourse in Literary
Cartography by Robert T. Tally Jr -- Time, Space, and the Human Geographies of Opportunity by Donald G. Janelle -- Losing Time and Space: Experiencing Immersion by Diana J. Reichenbach. <
ISBN:9783319444185
Series:eBooks
Series:Springer eBooks
Series:Springer 2017 package
Keywords: Physics , Epistemology , Metaphysics , Gravitation , Cosmology , Physics , Classical and Quantum Gravitation, Relativity Theory , Epistemology , History and Philosophical Foundations of Physics , Cosmology , Metaphysics
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Call number:9783319439648:ONLINE Show nearby items on shelf
Title:Earths of Distant Suns How We Find Them, Communicate with Them, and Maybe Even Travel There
Author(s): Michael Carroll
Date:2017
Size:1 online resource (XI, 234 p. 65 illus., 62 illus. in color p.)
Contents:Chapter One: A Place Like Home -- Chapter Two: Early Ideas and Lessons from Our Own Backyard -- Chapter Three: The Search for and Discovery of Exoplanets -- Chapter Four: Strange Solar System Architectures -- Chapter Five: Zeroing in
on Earth 2.0 -- Chapter Six: Looking for Life in All the Right Places -- Chapter Seven: Could We Make Contact? -- Chapter Eight: Could We Visit Earths of Distant Suns? -- Chapter Nine: First Contact: What Will It Mean? -- Index
ISBN:9783319439648
Series:eBooks
Series:Springer eBooks
Series:Springer 2017 package
Keywords: Popular works , Planetology , Astronomy , Popular Science , Popular Science in Astronomy , Space Sciences (including Extraterrestrial Physics, Space Exploration and Astron , Planetology
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Call number:9783319394459:ONLINE Show nearby items on shelf
Title:Maths Meets Myths: Quantitative Approaches to Ancient Narratives
Author(s):
Date:2017
Size:1 online resource (X, 228 p. 64 illus., 47 illus. in color p.)
Contents:Preface -- Foreword -- Introduction -- Cognitive and Network Constraints in Real Life and Literature -- A Networks Approach to Mythological Epics -- Medieval Historical, Hagiographical and Biographical Networks -- Peopling of the New
World from data on distributions of folklore motifs -- Phylogenetics Meets Folklore: Bioinformatic Approaches to the Study of International Folktales -- Analyses of a VirtualWorld -- Ghostscope: Conceptual Mapping of Supernatural
Phenomena in a Large Folklore Corpus -- Complex Networks of Words in Fables -- Analysing and Restoring the Chronology of the Irish Annals -- Mapping Literate Networks in Early Medieval Ireland Quantitative Realities, Social
Mythologies? -- How quantitative methods can shed light on a problem of comparative mythology: The myth of the struggle for supremacy between two groups of deities reconsidered
ISBN:9783319394459
Series:eBooks
Series:Springer eBooks
Series:Springer 2017 package
Keywords: Physics , History , Medieval philosophy , Historical linguistics , Social sciences , Physics , Applications of Graph Theory and Complex Networks , History, general , Methodology of the Social Sciences , Historical Linguistics , Medieval Philosophy
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Call number:9783319310428:ONLINE Show nearby items on shelf
Title:Star Ark A Living, Self-Sustaining Spaceship
Author(s):
Date:2017
Size:1 online resource (XXII, 492 p. 127 illus., 107 illus. in color p.)
Contents:Introduction by Rachel Armstrong -- Overview by Andrew Tziolas -- Metaphysics of Reality in Space by Rachel Armstrong -- Seeding the Universe with Life by Michael Mautner -- Space chemistry by Martin Hanczyc -- Living soils by Rachel
Armstrong -- Bacterial worlds by Simon Park -- Nature in space by Koert van Mensvoort -- The experience of space by Nelly Ben Hayoum -- Space architecture by Richard Hyams -- Extremophiles by Sarah Jane Pell.-Shrinking the human by
Arne Hendriks -- Human/mechanicals hybrids by Kevin Warwick -- Space birth by Lucy McCrae, Susan Crawford-Young, and Lynne Harper -- Establishing the ecological being by Rachel Armstrong -- Ecology of Mind by Noam Chomsky -- Humanity
in space by Steve Fuller -- Ecological politics by Jane Bennett -- Very large organizations by Jordan Geiger -- Architects building planets by Mark Morris
ISBN:9783319310428
Series:eBooks
Series:Springer eBooks
Series:Springer 2017 package
Keywords: Popular works , Design , Astronomy , Aerospace engineering , Astronautics , Popular Science , Popular Science in Astronomy , Space Sciences (including Extraterrestrial Physics, Space Exploration and Astron , Aerospace Technology and Astronautics , Design, general
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Call number:T11.F52::2005 Show nearby items on shelf
Title:A field guide for science writers : the official guide of the National Association of Science Writers
Author(s): Deborah Blum (ed.)
Mary Knudson (ed.)
Robin Marantz Henig (ed.)
Date:2006
Edition:2nd ed.
Publisher:Oxford University Press
Size:321 p
Contents:Learning the craft -- Choosing your market -- Varying your writing style -- Covering stories in the life sciences -- Covering stories in the physical and environmental sciences -- Taking a different path - journalists and public information officers -- Communicating science from institutions
ISBN:9780195174991
Keywords: Communication in science , Technical writing
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Call number:SPRINGER-2016-9789811008719:ONLINE Show nearby items on shelf
Title:Complex Surveys Analysis of Categorical Data
Author(s): Parimal Mukhopadhyay
Date:2016
Size:1 online resource (248 p.)
Note:10.1007/978-981-10-0871-9
Contents:Chapter 1. Preliminaries -- Chapter 2. The Design-Effects and Mis-Specification Effects -- Chapter 3. Some Classical Models in Categorical Data Analysis -- Chapter 4. Analysis of Categorical Data under a Full Model -- Chapter 5. Analysis of Catego rical Data under Log-Linear Models -- Chapter 6. Analysis of Categorical Data under Logistic Regression Model -- Chapter 7. Analysis in the Presence of Classification Errors -- Chapter 8. Approximate MLE’s from Survey Data
ISBN:9789811008719
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Statistics , Statistics , Statistical Theory and Methods , Statistics for Business/Economics/Mathematical Finance/Insurance , Statistics for Life Sciences, Medicine, Health Sciences , Statistics for Social Science, Behavorial Science, Education, Public Policy, and
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Call number:SPRINGER-2016-9784431559009:ONLINE Show nearby items on shelf
Title:Group-Sequential Clinical Trials with Multiple Co-Objectives
Author(s): Toshimitsu Hamasaki
Date:2016
Size:1 online resource (113 p.)
Note:10.1007/978-4-431-55900-9
Contents:1. Introduction -- 2. Early Stopping for Efficacy in Clinical Trials with multiple co-primary endpoints -- 3. Sample size recalculation based on observed effects at interim -- 4. Early stopping for futility in Clinical Trials with multiple co-prima ry endpoints -- 5. Early stopping for futility or Efficacy in Clinical Trials with multiple co-primary endpoints -- 6. Clinical Trials with multiple primary endpoints -- 7. Group-sequential designs for three-arm noninferiority clinical trials -- 8. Furthe r development: topics not covered in this book
ISBN:9784431559009
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Statistics , Statistics , Statistical Theory and Methods , Statistics for Life Sciences, Medicine, Health Sciences , Statistics for Social Science, Behavorial Science, Education, Public Policy, and
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Call number:SPRINGER-2016-9783662493328:ONLINE Show nearby items on shelf
Title:The Cox Model and Its Applications
Author(s): Mikhail Nikulin
Date:2016
Size:1 online resource (18 p.)
Note:10.1007/978-3-662-49332-8
Contents:Introduction: Several Classical Data Examples for Survival Analysis -- Elements of Survival Analysis -- The Cox Proportional Hazards Model -- The AFT, GPH, LT, Frailty, and GLPH Models -- Cross-effect Models of Survival Functions -- The Simple Cros s-effect Model -- Goodness-of-Fit for the Cox Model -- Remarks on Computations in Parametric and Semiparametric Estimation -- Cox Model for Degradation and Failure Time Data -- References -- Index
ISBN:9783662493328
Series:eBooks
Series:SpringerLink (Online service)
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Keywords: Statistics , Epidemiology , Biostatistics , Statistics , Statistical Theory and Methods , Statistics for Life Sciences, Medicine, Health Sciences , Biostatistics , Epidemiology
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Call number:SPRINGER-2016-9783658132347:ONLINE Show nearby items on shelf
Title:Analysis of Single-Cell Data ODE Constrained Mixture Modeling and Approximate Bayesian Computation
Author(s): Carolin Loos
Date:2016
Edition:1st ed. 2016
Size:1 online resource (92 p.)
Note:10.1007/978-3-658-13234-7
Contents:Modeling and Parameter Estimation for Single-Cell Data -- ODE Constrained Mixture Modeling for Multivariate Data -- Approximate Bayesian Computation Using Multivariate Statistics
ISBN:9783658132347
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Mathematics , Bioinformatics , Computational biology , Computer mathematics , Biomathematics , Mathematics , Mathematical and Computational Biology , Computational Mathematics and Numerical Analysis , Computer Appl. in Life Sciences
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Call number:SPRINGER-2016-9783319404134:ONLINE Show nearby items on shelf
Title:Mathematical and Statistical Modeling for Emerging and Re-emerging Infectious Diseases
Author(s):
Date:2016
Size:1 online resource (63 p.)
Note:10.1007/978-3-319-40413-4
Contents:Preface -- A Reality of Its Own -- Modeling the Impact of Behavior Change on the Spread of Ebola -- A model for coupled outbreaks contained by behavior change -- Real-time assessment of the international spreading risk associated with the 2014 West African Ebola Outbreak -- Modeling the case of early detection of Ebola virus disease -- Modeling ring vaccination strategies to control Ebola virus disease epidemics -- Estimation of the number of sickbeds during Ebola epidemics using optimal control the ory -- Inverse problems and Ebola virus disease using an age of infection model -- Assessing the Efficiency of Movement -- Restriction as a Control Strategy of Ebola -- Patch models of EVD transmission dynamics -- From bee species aggregation to models of disease avoidance: The \emph{Ben-Hur} effect} -- Designing Public Health Policies to Mitigate the Adverse Consequences of Rural-Urban Migration via Meta-Population Modeling -- Age of Infection Epidemic Models -- Optimal Control of
Vaccination in an Age-Structured Cholera Model -- A Multi-risk Model for Understanding the Spread of Chlamydia -- The 1997 Measles Outbreak in Metropolitan São Paulo, Brazil: Strategic Implications of Increasing Urbanization -- Methods to determine the end of an infectious disease epidemic: A short review -- Statistical considerations in infectious disease randomized controlled trials -- Epidemic models with and without mortality: when does it matter?- Capturing Household Transmission in Compartmen tal Models of Infectious Disease -- Bistable endemic states in a Susceptible-Infectious-Susceptible model with behavior-dependent Vaccination -- Index
ISBN:9783319404134
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Mathematics , Infectious diseases , Epidemiology , Probabilities , Statistics , Mathematics , Probability Theory and Stochastic Processes , Infectious Diseases , Statistics for Life Sciences, Medicine, Health Sciences , Epidemiology
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Call number:SPRINGER-2016-9783319327891:ONLINE Show nearby items on shelf
Title:Prior Processes and Their Applications Nonparametric Bayesian Estimation
Author(s): Eswar G Phadia
Date:2016
Edition:2nd ed. 2016
Size:1 online resource (327 p.)
Note:10.1007/978-3-319-32789-1
Contents:Prior Processes -- Inference Based on Complete Data -- Inference Based on Incomplete Data.
ISBN:9783319327891
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Statistics , Statistics , Statistical Theory and Methods , Statistics for Life Sciences, Medicine, Health Sciences , Statistics for Engineering, Physics, Computer Science, Chemistry and Earth Scien
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Call number:SPRINGER-2016-9783319327686:ONLINE Show nearby items on shelf
Title:Empirical Modeling and Data Analysis for Engineers and Applied Scientists
Author(s): Scott A Pardo
Date:2016
Size:1 online resource (61 p.)
Note:10.1007/978-3-319-32768-6
Contents:Preface -- Acknowledgments -- 1. Some Probability Concepts -- 2. Some Statistical Concepts -- 3. Measurement Systems Analysis -- 4. Modeling with Data -- 5. Factorial Experiments -- 6. Fractional Factorial Designs -- 7. Higher Order Approximations -- 8. Mixture Experiments -- 9. Some Examples and Applications -- 10. Binary Logistic Regression -- 11. Reliability, Life Testing, and Shelf Life -- 12. Some Bayesian Concepts -- 13. Validation and Verification -- 14. Simulation and Random Variable Genera tion -- 15. Taguchi Methods® and Robust Design -- References
ISBN:9783319327686
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Statistics , Biomedical engineering , Biochemical engineering , Chemical engineering , Environmental sciences , Statistics , Statistics for Engineering, Physics, Computer Science, Chemistry and Earth Scien , Statistical Theory and Methods , Biomedical Engineering/Biotechnology , Biochemical Engineering , Industrial Chemistry/Chemical Engineering , Environmental Science and Engineering
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Call number:SPRINGER-2016-9783319325620:ONLINE Show nearby items on shelf
Title:Group Sequential and Confirmatory Adaptive Designs in Clinical Trials
Author(s): Gernot Wassmer
Date:2016
Size:1 online resource (301 p.)
Note:10.1007/978-3-319-32562-0
Contents:Part I Group Sequential Designs -- Repeated Significance Tests: Procedures with Equally Sized Stages -- Procedures with Unequally Sized Stages -- Confidence Intervals, p -Values, and Point Estimation -- Applications -- Part II Adaptive Confirmatory Designs with a Single Hypothesis: Adaptive Group Sequential Tests -- Decision Tools for Adaptive Designs -- Estimation and p-Values for Two-stage Adaptive Designs -- Adaptive Designs with Survival Data -- Part III Adaptive Designs with Multiple Hypothese s: Multiple Testing in Adaptive Designs -- Applications and Case Studies -- Appendix - Software for Adaptive Designs -- Index
ISBN:9783319325620
Series:eBooks
Series:SpringerLink (Online service)
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Keywords: Statistics , Pharmaceutical technology , Pharmacy , Biostatistics , Statistics , Statistics for Life Sciences, Medicine, Health Sciences , Biostatistics , Drug Safety and Pharmacovigilance , Pharmaceutical Sciences/Technology
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Call number:SPRINGER-2016-9783319323770:ONLINE Show nearby items on shelf
Title:Pi: The Next Generation A Sourcebook on the Recent History of Pi and Its Computation
Author(s): David H Bailey
Date:2016
Size:1 online resource (507 p.)
Note:10.1007/978-3-319-32377-0
Contents:Foreword -- Preface -- Introduction -- Computation of pi using arithmetic-geometric mean -- Fast multiple-precision evaluation of elementary functions -- The arithmetic-geometric mean of Gauss -- The arithmetic-geometric mean and fast computation of elementary functions -- A simplified version of the fast algorithms of Brent and Salamin -- Is pi normal? -- The computation of pi to 29,360,000 decimal digits using Borweins' quartically convergent algorithm -- Gauss, Landen, Ramanujan, the arithmetic-g eometric mean, ellipses, pi, and the ladies diary -- Vectorization of multiple-precision arithmetic program and 201,326,000 decimal digits of pi calculation.-Ramanujan and pi -- 11. Ramanujan, modular equations, and approximations to pi or how to compute one billion digits of pi -- Pi, Euler numbers, and asymptotic expansions -- A spigot algorithm for the digits of pi -- On the rapid computation of various polylogarithmic constants -- Similarities in irrationality proofs for pi, ln 2, ζ(2),
and ζ(3) -- Unbounded spigot algorithms for the digits of pi -- Mathematics by experiment: Plausible reasoning in the 21st century -- Approximations to pi derived from integrals with nonnegative integrands -- Ramanujan's series for 1/π: A survey - - The computation of previously inaccessible digits of π2 and Catalan's constant -- Walking on real numbers -- Birth, growth and computation of pi to ten trillion digits -- Pi day is upon us again and we still do not know if pi is normal -- The Life of p i -- I prefer pi: A brief mathematical history and anthology of articles in the American Mathematical Monthly -- Bibliography -- Index
ISBN:9783319323770
Series:eBooks
Series:SpringerLink (Online service)
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Keywords: Mathematics , Computer mathematics , History , Number theory , Mathematics , Computational Mathematics and Numerical Analysis , Number Theory , History of Mathematical Sciences
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Call number:SPRINGER-2016-9783319320434:ONLINE Show nearby items on shelf
Title:The Mathematics Behind Biological Invasions
Author(s): Mark A Lewis
Date:2016
Size:1 online resource (19 p.)
Note:10.1007/978-3-319-32043-4
Contents:Introduction.-Dynamics of Biological Invasions.-Reaction-Diffusion Models: Single Species -- Invasion in a Multispecies System -- Long-Distance Dispersal and Spread -- A User’s Guide to Integrodifference Models for Invasive Spread -- Stochasticit y and Invasion Dynamics -- Stochastic Spread -- Assessing Invasion Risk -- Responding to invasions: Detection, control, and adaptation -- Appendix.-References.-Index
ISBN:9783319320434
Series:eBooks
Series:SpringerLink (Online service)
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Series:Interdisciplinary Applied Mathematics: 44
Keywords: Mathematics , Dynamics , Ergodic theory , Partial differential equations , Biomathematics , Statistics , Mathematics , Mathematical and Computational Biology , Statistics for Life Sciences, Medicine, Health Sciences , Genetics and Population Dynamics , Dynamical Systems and Ergodic Theory , Partial Differential Equations
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Call number:SPRINGER-2016-9783319312668:ONLINE Show nearby items on shelf
Title:mODa 11 - Advances in Model-Oriented Design and Analysis Proceedings of the 11th International Workshop in Model-Oriented Design and Analysis held in Hamminkeln, Germany, June 12-17, 2016
Author(s):
Date:2016
Size:1 online resource (11 p.)
Note:10.1007/978-3-319-31266-8
ISBN:9783319312668
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Statistics , Statistics , Statistical Theory and Methods , Statistics for Life Sciences, Medicine, Health Sciences , Statistics for Engineering, Physics, Computer Science, Chemistry and Earth Scien , Statistics and Computing/Statistics Programs
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Call number:SPRINGER-2016-9783319312453:ONLINE Show nearby items on shelf
Title:Applied Survival Analysis Using R
Author(s): Dirk F Moore
Date:2016
Size:1 online resource (26 p.)
Note:10.1007/978-3-319-31245-3
Contents:Introduction -- Basic Principles of Survival Analysis -- Nonparametric Survival Curve Estimation -- Nonparametric Comparison of Survival Distributions -- Regression Analysis Using the Proportional Hazards Model -- Model Selection and Interpretation -- Model Diagnostics -- Time Dependent Covariates -- Multiple Survival Outcomes and Competing Risks -- Parametric Models -- Sample Size Determination for Survival Studies -- Additional Topics -- References -- Appendix A -- Index -- R Package Index
ISBN:9783319312453
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Statistics , Epidemiology , Biostatistics , Statistics , Statistics for Life Sciences, Medicine, Health Sciences , Biostatistics , Statistical Theory and Methods , Epidemiology
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Call number:SPRINGER-2016-9783319306346:ONLINE Show nearby items on shelf
Title:Introduction to Nonparametric Statistics for the Biological Sciences Using R
Author(s): Thomas W MacFarland
Date:2016
Size:1 online resource (64 p.)
Note:10.1007/978-3-319-30634-6
Contents:Chapter 1 Nonparametric Statistics for the Biological Sciences -- Chapter 2 Sign Test -- Chapter 3 Chi-Square -- Chapter 4 Mann-Whitney U Test -- Chapter 5 Wilcoxon Matched-Pairs Signed-Ranks Test -- Chapter 6 Kruskal-Wallis H-Test for Oneway Analy sis of Variance (ANOVA) by Ranks -- Chapter 7 Friedman Twoway Analysis of Variance (ANOVA) by Ranks -- Chapter 8 Spearman's Rank-Difference Coefficient of Correlation -- Chapter 9 Other Nonparametric Tests for the Biological Sciences
ISBN:9783319306346
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Statistics , Agriculture , Biostatistics , Statistics , Statistics for Life Sciences, Medicine, Health Sciences , Statistics and Computing/Statistics Programs , Biostatistics , Agriculture , Statistical Theory and Methods
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Call number:SPRINGER-2016-9783319297767:ONLINE Show nearby items on shelf
Title:Modelling in Life Insurance – A Management Perspective
Author(s):
Date:2016
Size:1 online resource (38 p.)
Note:10.1007/978-3-319-29776-7
Contents:Paradigms in life insurance -- About market consistent valuation in insurance -- Cash flow projection models -- Economic scenario generators -- From internal to ORSA models -- Building a model: practical implementation -- Ex-ante model validation a nd back-testing -- The threat of model risk for insurance companies -- Meta-models and consistency issues -- Model feeding & Data Quality -- The role of models in management decision making -- Models and behaviour of stakeholders
ISBN:9783319297767
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Mathematics , Insurance , Economics, Mathematical , Actuarial science , Statistics , Mathematics , Quantitative Finance , Actuarial Sciences , Statistics for Business/Economics/Mathematical Finance/Insurance , Insurance
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Call number:SPRINGER-2016-9783319289854:ONLINE Show nearby items on shelf
Title:Excel 2013 for Health Services Management Statistics A Guide to Solving Practical Problems
Author(s): Thomas J Quirk
Date:2016
Edition:1st ed. 2016
Size:1 online resource (162 p.)
Note:10.1007/978-3-319-28985-4
Contents:Sample Size, Mean, Standard Deviation, and Standard Error of the Mean -- Random Number Generator -- Confidence Interval About the Mean Using the TINV Function and Hypothesis Testing -- One-Group t-Test for the Mean -- Two-Group t-Test of the Differ ence of the Means for Independent Groups -- Correlation and Simple Linear Regression -- Multiple Correlation and Multiple Regression -- One-Way Analysis of Variance (ANOVA) -- Appendix A: Answers to End-of-Chapter Practice Problems -- Appendix B: Practice Test -- Appendix C: Answers to Practice Test -- Appendix D: Statistical Formulas -- Appendix E: t-table.
ISBN:9783319289854
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Statistics , Health care management , Health services administration , Health administration , Statistics , Statistics for Life Sciences, Medicine, Health Sciences , Health Care Management , Health Administration
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Call number:SPRINGER-2016-9783319288932:ONLINE Show nearby items on shelf
Title:Data-driven Modelling of Structured Populations A Practical Guide to the Integral Projection Model
Author(s): Stephen P Ellner
Date:2016
Size:1 online resource (29 p.)
Note:10.1007/978-3-319-28893-2
Contents:Introduction -- Simple Deterministic IPM -- Basic Analysis 1: Demographic Measures and Events in the Life Cycle -- Basic Analysis 2: Prospective Perturbation Analysis -- Density Dependence -- General Deterministic IPM -- Environmental Stochasticity -- Spatial Models -- Evolutionary Demography -- Future Directions and Advanced Topics
ISBN:9783319288932
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Mathematics , Bioinformatics , Computational biology , Biomathematics , Mathematics , Mathematical and Computational Biology , Computer Appl. in Life Sciences
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Call number:SPRINGER-2016-9783319287706:ONLINE Show nearby items on shelf
Title:Permutation Statistical Methods An Integrated Approach
Author(s): Kenneth J Berry
Date:2016
Size:1 online resource (622 p.)
Note:10.1007/978-3-319-28770-6
Contents:Preface -- 1.Introduction -- 2.Completely Randomized Data -- 3.Randomized Designs: Interval Data -- 4.Regression Analysis of Interval Data -- 5.Randomized Designs: Ordinal Data, I -- 6.Randomized Designs: Ordinal Data, II -- 7.Randomized Designs: N ominal Data -- 8.Randomized Designs: Nominal Data -- 9.Randomized Block Designs: Interval Data -- 10.Randomized Block Designs: Ordinal Data -- 11.Randomized Block Designs: Nominal Data -- Epilogue -- References -- Author Index -- Subject Index
ISBN:9783319287706
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Statistics , History , Statistics , Statistical Theory and Methods , Statistics for Life Sciences, Medicine, Health Sciences , History of Science
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Call number:SPRINGER-2016-9783319285887:ONLINE Show nearby items on shelf
Title:Computational Diffusion MRI MICCAI Workshop, Munich, Germany, October 9th, 2015
Author(s):
Date:2016
Size:1 online resource (63 p.)
Note:10.1007/978-3-319-28588-7
Contents:An Efficient Finite Element Solution of the Generalised Bloch-Torrey Equation for Arbitrary Domains: L. Beltrachini et al -- Super-Resolution Reconstruction of Diffusion-Weighted Images using 4D Low-Rank and Total Variation: Feng Shi et al -- Holist ic Image Reconstruction for Diffusion MRI: V. Golkov et al -- Alzheimer’s Disease Classification with Novel Microstructural Metrics from Diffusion-Weighted MRI: T. M. Nir et al -- Brain Tissue Micro-Structure Imaging from Diffusion MRI Using Least Squar es Variable Separation: H. Farooq et al -- Multi-Tensor MAPMRI: How to Estimate Microstructural Information from Crossing Fibers: M. Zucchelli et al -- On the Use of Antipodal Optimal Dimensionality Sampling Scheme on the Sphere for Recovering Intra-Voxel Fibre Structure in Diffusion MRI: A.P. Bates et al -- Estimation of Fiber Orientations Using Neighborhood Information: C. Ye et al -- A framework for creating population specific multimodal brain atlas using clinical T1 and diffusion tensor
images: V. Gupta et al -- Alignment of Tractograms as Linear Assignment Problem: N. Sharmin -- Accelerating Global Tractography Using Parallel Markov Chain Monte Carlo: H. Wu et al -- Adaptive Enhancement in Diffusion MRI Through Propagator Sharpeni ng: T. Dela Haije et al -- Angular Resolution Enhancement of Diffusion MRI Data Using Inter-Image Information Transfer: Geng Chen et al -- Crossing versus Fanning: Model Comparison Using HCP Data: A. Ghosh et al -- White Matter Fiber Set Simplification by Redundancy Reduction with Minimum Anatomical Information Loss: G. Zimmerman Moreno et al -- A Temperature Phantom to Probe the Ensemble Average Propagator Asymmetry: an In-Silico Study: M. Pizzolato et al -- Registration Strategies for Whole-Body Diffusi on-Weighted MRI Stitching: J. Ceranka et al -- HARDI Feature Selection, Registration and Atlas Building for A$\beta$ Pathology Classification: E. Schwab et al -- Reliability of Structural Connectivity Examined with Four Different Diffusion
Reconstruction Methods at Two Different Spatial and Angular Resolutions: J. E. Villalon-Reina et al
ISBN:9783319285887
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Mathematics , Computer simulation , Image processing , Bioinformatics , Computer mathematics , Visualization , Statistics , Mathematics , Visualization , Computational Biology/Bioinformatics , Computational Science and Engineering , Simulation and Modeling , Image Processing and Computer Vision , Statistics for Life Sciences, Medicine, Health Sciences
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Call number:SPRINGER-2016-9783319283166:ONLINE Show nearby items on shelf
Title:An Introduction to Statistics with Python With Applications in the Life Sciences
Author(s): Thomas Haslwanter
Date:2016
Size:1 online resource (85 p.)
Note:10.1007/978-3-319-28316-6
Contents:Part I: Python and Statistics -- Why Statistics? -- Python -- Data Input -- Display of Statistical Data -- Part II: Distributions and Hypothesis Tests -- Background -- Distributions of One Variable -- Hypothesis Tests -- Tests of Means of Numerical Data -- Tests on Categorical Data -- Analysis of Survival Times -- Part III: Statistical Modelling -- Linear Regression Models -- Multivariate Data Analysis -- Tests on Discrete Data -- Bayesian Statistics -- Solutions -- Glossary -- Index
ISBN:9783319283166
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Statistics , Programming languages (Electronic computers) , Biostatistics , Computer mathematics , Statistics , Statistics and Computing/Statistics Programs , Statistics for Life Sciences, Medicine, Health Sciences , Biostatistics , Computational Science and Engineering , Programming Languages, Compilers, Interpreters
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Call number:SPRINGER-2016-9783319281582:ONLINE Show nearby items on shelf
Title:Modeling Discrete Time-to-Event Data
Author(s): Gerhard Tutz
Date:2016
Size:1 online resource (3 p.)
Note:10.1007/978-3-319-28158-2
Contents:Introduction -- The Life Table -- Basic Regression Models -- Evaluation and Model Choice -- Nonparametric Modelling and Smooth Effects -- Tree-Based Approaches -- High-Dimensional Models - Structuring and Selection of Predictors -- Competing Risks Models -- Multiple-Spell Analysis -- Frailty Models and Heterogeneity -- Multiple-Spell Analysis -- List of Examples -- Bibliography -- Subject Index -- Author Index
ISBN:9783319281582
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Statistics , Statistics , Statistical Theory and Methods , Statistics for Life Sciences, Medicine, Health Sciences , Statistics for Social Science, Behavorial Science, Education, Public Policy, and , Statistics and Computing/Statistics Programs
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Call number:SPRINGER-2016-9783319279831:ONLINE Show nearby items on shelf
Title:Sigma 7 The Six Mercury Orbits of Walter M. Schirra, Jr.
Author(s): Colin Burgess
Date:2016
Size:1 online resource (82 p.)
Note:10.1007/978-3-319-27983-1
Contents:Foreword by Tracy Kornfeld -- Acknowledgements -- Author Prologue -- Chapter 1: A flier’s son.- Chapter 2: The making of a flight-ready astronaut -- Chapter 3: The art of space flight -- Chapter 4: Sigma 7 flies -- Chapter 5: “A sweet
little bird” -- Chapter 6: Press conferences, parades, and post-flight honors -- Chapter 7: A Life beyond Apollo -- Chapter 8: Final Salute to a hero -- Appendices -- Index
ISBN:9783319279831
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Popular works , History , Space sciences , Astronomy , Aerospace engineering , Astronautics , Popular Science , Popular Science in Astronomy , Extraterrestrial Physics, Space Sciences , Aerospace Technology and Astronautics , History of Science
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Call number:SPRINGER-2016-9783319279398:ONLINE Show nearby items on shelf
Title:Mathematics in Everyday Life
Author(s): John Haigh
Date:2016
Edition:1st ed. 2016
Size:1 online resource (14 p.)
Note:10.1007/978-3-319-27939-8
Contents:Money -- Differential Equations -- Sport and Games -- Business Applications -- Social Sciences -- TV Game Shows
ISBN:9783319279398
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Mathematics , Differential equations , Game theory , Mathematical models , Mathematics , Mathematics, general , Ordinary Differential Equations , Game Theory, Economics, Social and Behav. Sciences , Mathematical Modeling and Industrial Mathematics
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Call number:SPRINGER-2016-9783319271675:ONLINE Show nearby items on shelf
Title:Research Methodology The Aims, Practices and Ethics of Science
Author(s): Peter Pruzan
Date:2016
Edition:1st ed. 2016
Size:1 online resource (1 p.)
Note:10.1007/978-3-319-27167-5
Contents:Introduction -- Science -- Hypotheses, Theories and Laws -- Scientific Statements: Their Justification and Acceptance -- Measurement -- Experimentation -- Scientific Method and the Design of Research -- Uncertainty, Probability and
Statistics in Research -- Research -- Ethics and Responsibility in Scientific Research
ISBN:9783319271675
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Physics , Research , Science education , Physical measurements , Measurement , Statistics , Sociology , Physics , Measurement Science and Instrumentation , Research Ethics , Research Methodology , Statistics for Life Sciences, Medicine, Health Sciences , Science Education
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Call number:SPRINGER-2016-9783319270999:ONLINE Show nearby items on shelf
Title:Statistical Analysis for High-Dimensional Data The Abel Symposium 2014
Author(s):
Date:2016
Edition:1st ed. 2016
Size:1 online resource (19 p.)
Note:10.1007/978-3-319-27099-9
Contents:Some Themes in High-Dimensional Statistics: A. Frigessi et al -- Laplace Appoximation in High-Dimensional Bayesian Regression: R. Barber, M. Drton et al -- Preselection in Lasso-Type Analysis for Ultra-High Dimensional Genomic Exploration: L.C. Berg ersen, I. Glad et al -- Spectral Clustering and Block Models: a Review and a new Algorithm: S. Bhattacharyya et al -- Bayesian Hierarchical Mixture Models: L. Bottelo et al -- iBATCGH Integrative Bayesian Analysis of Transcriptomic and CGH Data: Cassese, M. Vannucci et al -- Models of Random Sparse Eigenmatrices and Bayesian Analysis of Multivariate Structure: A.J. Cron, M. West -- Combining Single and Paired End RNA-seq Data for Differential Expression Analysis: F. Feng, T.Speed et al -- An Imputation Me thod for Estimation the Learning Curve in Classification Problems: E. Laber et al -- Baysian Feature Allocation Models for Tumor Heterogeneity: J. Lee, P. Mueller et al -- Bayesian Penalty Mixing: The Case of a Non-Separable Penalty: V.
Rockova et al -- Confidence Intervals for Maximin Effects in Inhomogeneous Large Scale Data: D. Rothenhausler et al -- Chisquare Confidence Sets in High-Dimensional Regression: S. van de Geer et al.
ISBN:9783319270999
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:Abel Symposia: 11
Keywords: Mathematics , Bioinformatics , Computer mathematics , Statistics , Mathematics , Computational Mathematics and Numerical Analysis , Statistical Theory and Methods , Bioinformatics , Statistics and Computing/Statistics Programs , Statistics for Life Sciences, Medicine, Health Sciences , Statistics for Engineering, Physics, Computer Science, Chemistry and Earth Scien
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Call number:SPRINGER-2016-9783319269115:ONLINE Show nearby items on shelf
Title:Stochastic Neuron Models
Author(s): Priscilla E Greenwood
Date:2016
Edition:1st ed. 2016
Size:1 online resource (12 p.)
Note:10.1007/978-3-319-26911-5
Contents:Introduction -- Single Neuron Models -- Population and Subpopulation Models -- Spatially-structured Neural Systems -- The Bigger Picture
ISBN:9783319269115
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:Mathematical Biosciences Institute Lecture Series : 1.5
Keywords: Mathematics , Neurosciences , Probabilities , Biomathematics , Statistics , Mathematics , Physiological, Cellular and Medical Topics , Probability Theory and Stochastic Processes , Neurosciences , Statistics for Life Sciences, Medicine, Health Sciences
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Call number:SPRINGER-2016-9783319255682:ONLINE Show nearby items on shelf
Title:My Search for Ramanujan How I Learned to Count
Author(s): Ken Ono
Date:2016
Size:1 online resource (10 p.)
Note:10.1007/978-3-319-25568-2
Contents:Prologue -- Part I: My Life Before Ramanujan -- Tiger Boy -- My roots -- My childhood -- An Unexpected Letter -- My escape -- Part II: The Legend of Ramanujan -- Little lord -- A creative genius -- An addiction -- Goddess -- Purgatory -- Janaki -- I beg to introduce myself -- These formulas defeated me completely -- Permission from a Goddess -- Together at last -- Culture Shock -- Triumph over racism -- English malaise -- Ramanujan's homecoming -- The tragic end -- Part III: My Life Adrift -- I beli eve in Santa -- Out of the frying pan and into the fire -- Erika -- The Pirate Professor -- Growing pains -- Part IV: Finding my way -- My teacher -- Hitting bottom -- A miracle -- My Hardy -- Hitting my stride -- Bittersweet reunion -- I count now -- The idea of Ramanujan -- My spirituality -- Epilogue -- My pilgrimages -- Face to Face with Ramanujan -- My search goes on -- Afterword -- Two Questions -- Fermat's Last Theorem and the Tokyo-Nikko Conference -- Mathematical gems --
Ramanujan's 1729 Taxicab number -- Approximations to p -- Highly composite numbers -- Euler's partition numbers -- Rogers-Ramanujan identities -- Ramanujan's tau-function
ISBN:9783319255682
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Mathematics , History , Number theory , Mathematics , Number Theory , History of Mathematical Sciences , History of Science
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Call number:SPRINGER-2016-9783319245232:ONLINE Show nearby items on shelf
Title:Visualization in Medicine and Life Sciences III Towards Making an Impact
Author(s):
Date:2016
Size:1 online resource (132 p.)
Note:10.1007/978-3-319-24523-2
Contents:Segmentation and Uncertainty -- Visualization of 3D Medical Images -- Visualization for Diffusion-weighted Imaging -- Cohort Studies and Time-varying Phenomena -- Visualization in Life Sciences
ISBN:9783319245232
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Mathematics , User interfaces (Computer systems) , Computer graphics , Image processing , Visualization , Mathematics , Visualization , User Interfaces and Human Computer Interaction , Computer Graphics , Image Processing and Computer Vision
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Call number:SPRINGER-2016-9783319244488:ONLINE Show nearby items on shelf
Title:Physical Models of Cell Motility
Author(s):
Date:2016
Edition:1st ed. 2016
Size:1 online resource (9 p.)
Note:10.1007/978-3-319-24448-8
Contents:Introduction -- Phase-field Description of Cell Movement -- Role of Substrate Adhesiveness -- Cytoskeletal Waves -- Chemical Signaling -- Efficiency of Cell Motion
ISBN:9783319244488
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Physics , Bioinformatics , Computational biology , Biomathematics , Biophysics , Biological physics , Biomedical engineering , Physics , Biophysics and Biological Physics , Biomedical Engineering , Computer Appl. in Life Sciences , Numerical and Computational Physics , Physiological, Cellular and Medical Topics
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Call number:SPRINGER-2016-9783319235585:ONLINE Show nearby items on shelf
Title:Nonclinical Statistics for Pharmaceutical and Biotechnology Industries
Author(s):
Date:2016
Edition:1st ed. 2016
Size:1 online resource (113 p.)
Note:10.1007/978-3-319-23558-5
Contents:Introduction to Nonclinical Statistics for Pharmaceutical and Biotechnology Industries -- Regulatory Nonclinical Statistics -- How to be a good nonclinical statistician -- Statistical Methods for Drug Discovery -- High-throughput Screening Data Anal ysis -- Quantitative-Structure Activity Relationship Modeling and Cheminformatics -- GWAS for Drug Discovery -- Statistical applications in Design and Analysis of In-Vitro Safety Screening Assays -- Nonclinical safety assessment: an introduction for stati sticians -- General Toxicology, Safety Pharmacology, Reproductive Toxicology and Juvenile Toxicology Studies -- Clinical Assays for Biological Macromolecules -- Recent Research Projects by FDA's Pharmacology and Toxicology Statistics Team -- Design and ev aluation of drug combination studies -- Biomarkers -- Overview of Drug Development and Statistical Tools for Manufacturing and Testing -- Assay Validation -- Lifecycle Approach to Bioassay -- Quality by Design: Building Quality into
Products and Processes -- Process Validation -- Acceptance Sampling -- Process Capability and Statistical Process Control -- Statistical Considerations for Stability and the Estimation of Shelf Life.- In Vitro Dissolution Testing: Statistical Approa ches and Issues -- Assessing Content Uniformity -- Chemometrics and Predictive Modelling -- Statistical Methods for Comparability Studies
ISBN:9783319235585
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Statistics , Pharmacology , Medicine , Statistics , Statistics for Life Sciences, Medicine, Health Sciences , Medicine/Public Health, general , Pharmacology/Toxicology
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Call number:SPRINGER-2016-9783319235431:ONLINE Show nearby items on shelf
Title:The Amazing Unity of the Universe And Its Origin in the Big Bang
Author(s): Edward van den Heuvel
Date:2016
Edition:2nd ed. 2016
Size:1 online resource (172 p.)
Note:10.1007/978-3-319-23543-1
Contents:Our Strange Universe -- The Sun’s Backyard: Our Solar System -- How Distant Are the Stars?- The Discovery of the Structure of Our Milky Way Galaxy -- The Chemical Composition of the Sun and Stars -- Other Galaxies and the Discovery of
the Expansion of the Universe -- Gravity According to Galilei, Newton, Einstein and Mach -- Einstein, de Sitter, Friedmann, Lemaitre and the Evolution of the Universe -- The Big Bang as the Origin of the Universe -- The Origin of the
Matter in the Universe -- We Are Made of Stardust: Timescales of the Universe and of Life -- Is the Universe Open, Closed or Flat? The Horizon Problem, the Flatness Problem and Inflation -- Dark Matter and Dark Energy: Our Strange
Universe -- Ripples in the Cosmic Microwave Background Radiation -- Time in the Universe -- From Universe to Multiverse -- Intelligent Life Elsewhere in the Universe -- Epilogue -- Appendices
ISBN:9783319235431
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Physics , Space sciences , Cosmology , Astronomy , Physics , Cosmology , Popular Science in Astronomy , Extraterrestrial Physics, Space Sciences
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Call number:SPRINGER-2016-9783319231020:ONLINE Show nearby items on shelf
Title:Mathematician for All Seasons Recollections and Notes, Vol. 2 (1945–1968)
Author(s): Hugo Steinhaus
Date:2016
Edition:1st ed. 2016
Size:1 online resource (20 p.)
Note:10.1007/978-3-319-23102-0
Contents:Foreword to the first Polish edition -- Introduction to the English edition -- Part I: Jaslo -- The Gymnasium -- In the capital Lwów -- Göttingen -- The return home -- The life of a private scholar -- Part II: In the university town Lwów -- The first occupation -- Interlude: Flashes of memory -- The second occupation -- Homeless wandering -- Osiczyna -- Interlude: Flashes of memory -- Stróze -- Diary entries -- A flash of memory -- Diary entries (continued) -- Between Kraków and Wroclaw -- Wro claw -- A taste of America -- Wroclaw again -- America again -- Home again -- Index of names
ISBN:9783319231020
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:Vita Mathematica : 19
Keywords: Mathematics , History , Mathematics , History of Mathematical Sciences , History, general
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Call number:SPRINGER-2016-9783319211152:ONLINE Show nearby items on shelf
Title:A Man From Planet Earth A Scientific Novel
Author(s): Giancarlo Genta
Date:2016
Edition:1st ed. 2016
Size:1 online resource (1 p.)
Note:10.1007/978-3-319-21115-2
Contents:Preface -- part i: novel -- part ii: scientific -- Appendix
ISBN:9783319211152
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Popular works , Astrobiology , Astronomy , Earth , Geology , Physics , Popular Science , Popular Science in Astronomy , Astrobiology , Popular Life Sciences , Popular Science in Physics , Popular Earth Science
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Call number:SPRINGER-2016-9783319201344:ONLINE Show nearby items on shelf
Title:Galileo and the Equations of Motion
Author(s): Dino Boccaletti
Date:2016
Edition:1st ed. 2016
Size:1 online resource (175 p.)
Note:10.1007/978-3-319-20134-4
Contents:Part I The Theories on the Motion of Bodies in the Classical Antiquity -- Kinematics among the Greeks -- Dynamics in the Opinion of Aristotle and his Continuators -- The Theories of Motion in the Middle Ages and in the Renaissance --
The first substantial Criticisms to Aristotelian Mechanics – Philoponus and Avempace -- The medieval Kinematics -- Part II A brief Chronology of Galileo’s Life -- The young Galileo and the De Motu -- The Inertia Principle.-The Law of
Fall and the Motion of Projectiles -- The Principle of Relativity
ISBN:9783319201344
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Physics , History , Mathematical physics , Mechanics , Observations, Astronomical , Astronomy , Physics , Mechanics , History and Philosophical Foundations of Physics , Astronomy, Observations and Techniques , History of Science , Mathematical Applications in the Physical Sciences
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Call number:SPRINGER-2016-9783319193601:ONLINE Show nearby items on shelf
Title:Nanosciences and Nanotechnology Evolution or Revolution?
Author(s):
Date:2016
Edition:1st ed. 2016
Size:1 online resource (185 p.)
Note:10.1007/978-3-319-19360-1
Contents:From the Contents: Introduction : The Nanoscale -- Part I Nanophysics – Nanoelectronics & Nanophotonics -- Part II Nanomaterials and Nanochemistry -- General Overview.- Part III Nanobiosciences, Nanomedicine & Nanotoxicology -- New
Tools and Concepts for Investigation and Manipulation in Life Sciences.- Part IV Nanotechnology and Society -- Overview of Fundamental Research, Educational Structures, Industrial Development of Nanotechnologies in France and Worldwide
ISBN:9783319193601
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Physics , Nanochemistry , Nanoscale science , Nanoscience , Nanostructures , Science , Nanotechnology , Physics , Nanoscale Science and Technology , Nanotechnology and Microengineering , Nanotechnology , Nanochemistry , Societal Aspects of Physics
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Call number:SPRINGER-2016-9783319179308:ONLINE Show nearby items on shelf
Title:Physical Sciences and Engineering Advances in Life Sciences and Oncology A WTEC Global Assessment
Author(s):
Date:2016
Size:1 online resource (196 p.)
Note:10.1007/978-3-319-17930-8
Contents:Foreword -- Executive Summary -- Preface -- ToC -- List of Figures.-Chapter 1 -- Introduction -- Chapter 2 -- Complexity and Information: Cancer as a Multiscale Complex Adaptive System -- Chapter 3 -- Mimicking the Microenvironement
-- Chapter 4.- Cancer Cell Mechanics -- Chapter 5.- Fluid Mechanics and Transport in Tumors -- Chapter 6 -- The Dynamics of Cell Motility -- Chapter 7.- Devices and New Diagnostic Principles -- Chapter 8 -- Clinical Perspective --
Appendix A. APHELION Study Panelists and Advisors -- Appendix B. Site Visit Reports - Europe -- Appendix C. Site Visit Reports - Asia -- Appendix D. Site Visit Reports - United Kingdom -- Appendix E. Site Visit Reports - Brazil --
Appendix F. Recent Conferences
ISBN:9783319179308
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Physics , Oncology , Biochemistry , Biophysics , Biological physics , Medical physics , Radiation , Statistical physics , Dynamical systems , Biomedical engineering , Physics , Biophysics and Biological Physics , Oncology , Biomedical Engineering , Medical and Radiation Physics , Biochemistry, general , Statistical Physics, Dynamical Systems and Complexity
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Call number:SPRINGER-2014-9789401787895:ONLINE Show nearby items on shelf
Title:The Earth's Hydrological Cycle [electronic resource]
Author(s): Lennart Bengtsson
R.-M Bonnet
M Calisto
G Destouni
R Gurney
J Johannessen
Y Kerr
W.A Lahoz
M Rast
Date:2014
Publisher:Dordrecht : Springer Netherlands : Imprint: Springer
Size:1 online resource
Note:This book gives a comprehensive presentation of our present understanding of the Earth's Hydrological cycle and the problems, consequences and impacts that go with this topic. Water is a central component in the Earth's system.It is indispensable for life on Earth in its present form and influences virtually every aspect of our planet's life support system. On relatively short time scales, atmospheric water vapor interacts with the atmospheric circulationand is crucial in forming the Earth's climate zones. Water vapor is the most powerful of the greenhouse gases and serves to enhance the tropospheric temperature. The dominant part of available water on Earth resides in the oceans.Parts are locked up in the land ice on Greenland and Antarctica and a s maller part is estimated to exist as groundwater. If all the ice over the land and all the glaciers were to melt, the sea level would rise by some 80 m. Incomparison, the total amount of water vapor in the atmosphere is small it amounts to ~ 25 kg/m2, or the equivalent of 25 mm water for each column of air. Yet atmospheric water vapor is crucial for the Earths energy balance. Thebook gives an up to date presentation of the present knowledge. Previously published in Surveys in Geophysics, Volume 35, No. 3, 2014
Contents:Foreword
Review of understanding of Earths hydrological cycle: Observations, theory and modeling
Challenges in water cycle research
Physically consistent responses of the global atmospheric cycle in models and observations
Quantifying and reducing uncertainties in the large scale response of the water cycle
Conceptual problems in Land Surface Data Assimilation
Initialisation of land surface variables for Numerical Weather Prediction
Closing the gaps in our knowledge of the hydrological cycle over land: Conceptual problems
Toward improved estimation of the dynamic top
ISBN:9789401787895
Series:eBooks
Series:SpringerLink
Series:Space Sciences Series of ISSI, 1385-7525 : v46
Series:Physics and Astronomy (Springer-11651)
Keywords: Environmental sciences , Oceanography , Climatic changes
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Call number:SPRINGER-2014-9783642549335:ONLINE Show nearby items on shelf
Title:Channeling and Radiation in Periodically Bent Crystals [electronic resource]
Author(s): Andrey V Korol
Andrey V Solov'yov
Walter Greiner
Date:2014
Edition:2nd ed. 2014
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer
Size:1 online resource
Note:The development of coherent radiation sources for sub-angstrom wavelengths - i.e. in the hard X-ray and gamma-ray range - is a challenging goal of modern physics. The availability of such sources will have many applications inbasic science, technolog y and medicine, and, in particular, they may have a revolutionary impact on nuclear and solid state physics, as well as on the life sciences. The present state-of-the-art lasers are capable of emittingelectromagnetic radiation from the infrared to the ult raviolet, while free electron lasers (X-FELs) are now entering the soft X-ray region. Moving further, i.e. into the hard X and/or gamma ray band, however, is not possible withoutnew approaches and technologies. In this book we introduce and discuss one s uch novel approach -the radiation formed in a Crystalline Undulator -whereby electromagnetic radiation is generated by a bunch of ultra-relativisticparticles channeling through a periodically bent crystalline structure. Under certain conditions, such a de vice can emit intensive spontaneous monochromatic radiation and even reach the coherence of laser light sources. Readers willbe presented with the underlying fundamental physics and be familiarized with the theoretical, experimental and technological adv ances made during the last one and a half decades in exploring the various features of investigations intocrystalline undulators. This research draws upon knowledge from many research fields - such as materials science, beam physics, the physics of radiat ion, solid state physics and acoustics, to name but a few. Accordingly, much carehas been taken by the authors to make the book as self-contained as possible in this respect, so as to also provide a useful introduction to this emerging field to a broad re adership of researchers and scientist with variousbackgrounds. This new edition has been revised and extended to take recent developments in the field into account.
Contents:Introduction
Related Phenomena
Schemes for Periodic Bending of Crystals
Feasability of a Positron
Based Crystalline Undulator
Positron
Based CU: Illustrative Material
CUs for Electrons and Heavy Particles
Experimental Studies of CUR
Stimulated Emission from CU
Conclusion
References
Index
ISBN:9783642549335
Series:eBooks
Series:SpringerLink
Series:Springer Series on Atomic, Optical, and Plasma Physics, 1615-5653 : v69
Series:Physics and Astronomy (Springer-11651)
Keywords: Particle acceleration , Crystallography
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Call number:SPRINGER-2014-9783642538391:ONLINE Show nearby items on shelf
Title:Membrane Transport Mechanism [electronic resource] : 3D Structure and Beyond
Author(s): Reinhard Krmer
Christine Ziegler
Date:2014
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer
Size:1 online resource
Note:This book provides a molecular view of membrane transport by means of numerous biochemical and biophysical techniques. The rapidly growing number of atomic structures of transporters in different conformations and the constantprogress in bioinformati cs have recently added deeper insights. The unifying mechanism of energized solute transport across membranes is assumed to consist of the conformational cycling of a carrier protein to provide access tosubstrate binding sites from either side of a cellu lar membrane. Due to the central role of active membrane transport there is considerable interest in deciphering the principles of one of the most fundamental processes in nature: thealternating access mechanism. This book brings together particularly si gnificant structure-function studies on a variety of carrier systems from different transporter families: Glutamate symporters, LeuT-like fold transporters, MFStransporters and SMR (RND) exporters, as well as ABC-type importers. The selected examples imp ressively demonstrate how the combination of functional analysis, crystallography, investigation of dynamics and computational studies hasmade it possible to create a conclusive picture, or, more precisely, a molecular movie. Although we are still far fro m a complete molecular description of the alternating access mechanism, remarkable progress has been made fromstatic snapshots towards membrane transport dynamics
Contents:Dance Lessons for Proteins: The Dynamics and Thermodynamics of a Sodium/Aspartate Symporter
Characterizing the Structure, Function and Evolution of Human Solute Carrier (SLC) Transporters Using Computational Approaches
Structures of the Prokaryotic Galactose Transporter vSGLT and Their Implications on Alternating Access Mechanism in Human SGLT1
Moving Crystallographic Snapshots: A Mechanism for Transport Regulation in BetP
Development of Refined Homology Models: Adding the Missing Information to the Medically Relevant Neurotransmitter Transporters
The Life and Times of Lac Perme
ISBN:9783642538391
Series:eBooks
Series:SpringerLink
Series:Springer Series in Biophysics, 0932-2353 : v17
Series:Physics and Astronomy (Springer-11651)
Keywords: Life sciences , Bioinformatics , Biochemistry , Cell membranes , Crystallography
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Call number:SPRINGER-2014-9783642367366:ONLINE Show nearby items on shelf
Title:From Alexandria, Through Baghdad [electronic resource] : Surveys and Studies in the Ancient Greek and Medieval Islamic Mathematical Sciences in Honor of J.L. Berggren
Author(s): Nathan Sidoli
Glen Van Brummelen
Date:2014
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer
Size:1 online resource
Note:This book honors the career of historian of mathematics J.L. Berggren, his scholarship, and service to the broader community. The first part, of value to scholars, graduate students, and interested readers, is a survey ofscholarship in the mathematic al sciences in ancient Greece and medieval Islam. It consists of six articles (three by Berggren himself) covering research from the middle of the 20th century to the present. The remainder of the bookcontains studies by eminent scholars of the ancient an d medieval mathematical sciences. They serve both as examples of the breadth of current approaches and topics, and as tributes to Berggren's interests by his friends andcolleagues
Contents:History of Greek Mathematics
Mathematical Reconstructions Out, Textual Studies in
Research on Ancient Greek Mathematical Sciences
History of Mathematics in the Islamic World
Mathematics and Her Sisters in Medieval Islam
A Survey of Research in the Mathematical Sciences in Medieval Islam from 1996 to 2011
The Life of Pi: From Archimedes to ENIAC and Beyond
Mechanical Astronomy: A Route to the Ancient Discovery of Epicycles and Eccentrics
Some Greek Sundial Meridians
An Archimedean Proof of Herons Formula for the Area of a Triangle
Reading the Lost Folia of the A
ISBN:9783642367366
Series:eBooks
Series:SpringerLink
Series:Mathematics and Statistics (Springer-11649)
Keywords: Mathematics
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Call number:SPRINGER-2014-9783642195983:ONLINE Show nearby items on shelf
Title:Basic Concepts in Physics [electronic resource] : From the Cosmos to Quarks
Author(s): Masud Chaichian
Hugo Perez Rojas
Anca Tureanu
Date:2014
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer
Size:1 online resource
Note:Basic Concepts in Physics: From the Cosmos to Quarks is the outcome of the authors' long and varied teaching experience in different countries and for different audiences, and gives an accessible and eminently readableintroduction to all the main ide as of modern physics. The books fresh approach, using a novel combination of historical and conceptual viewpoints, makes it ideal complementary reading to more standard textbooks. The first fivechapters are devoted to classical physics, from planetary mot ion to special relativity, always keeping in mind its relevance to questions of contemporary interest. The next six chapters deal mainly with newer developments in physics,from quantum theory and general relativity to grand unified theories, and the book concludes by discussing the role of physics in living systems. A basic grounding in mathematics is required of the reader, but technicalities areavoided as far as possible thus complex calculations are omitted so long as the essential ideas remain clear. The book is addressed to undergraduate and graduate students in physics and will also be appreciated by many professionalphysicists. It will likewise beof interest to students, researchers and teachers of other natural sciences, as well as to engineers, h igh-school teachers and the curious general reader, who will come to understand what physics isabout and how it describes the different phenomena of Nature. Not only will readers of this book learn much about physics, they will also learn to love it.
Contents:Gravitation and Newton Laws
Entropy, Statistical Physics and Information
Electromagnetism and Maxwell Equations
Electromagnetic Waves
The Special Theory of Relativity
The Atom and Quantum Theory
Quantum Electrodynamics
Fermi
Dirac and Bose
Einstein Statistics
The Four Fundamental Forces
General Relativity and Cosmology
Unification of the Forces of Nature
Physics and Life
Index
ISBN:9783642195983
Series:eBooks
Series:SpringerLink
Series:Undergraduate Lecture Notes in Physics, 2192-4791
Series:Physics and Astronomy (Springer-11651)
Keywords: Biochemistry
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Call number:SPRINGER-2014-9783319050140:ONLINE Show nearby items on shelf
Title:Mathematical and Statistical Methods for Actuarial Sciences and Finance [electronic resource]
Author(s): Cira Perna
Marilena Sibillo
Date:2014
Publisher:Cham : Springer International Publishing : Imprint: Springer
Size:1 online resource
Note:The interaction between mathematicians and statisticians working in the actuarial and financial fields is producing numerous meaningful scientific results. This volume, comprising a series of four-page papers, gathers new ideasrelating to mathematica l and statistical methods in the actuarial sciences and finance. The book covers a variety of topics of interest from both theoretical and applied perspectives, including: actuarial models alternative testingapproaches behavioral finance clustering techni ques coherent and non-coherent risk measures credit-scoring approaches data envelopment analysis dynamic stochastic programming financial contagion models financial ratios
Contents:1 I. Albarrn, P. Alonso, A.Arribas
Gil and A. Gran: Can personal dependency paths help to estimate life expectancy free of dependency?
2 A. Amendola and V. Candila: Evaluation of volatility forecasts in a VaR framework
3 A. Amendola and M. Restaino: Optimal cut
off points for multiple causes of business failure models
4 R. Baragona, F. Battaglia and D. Cucina: Maximum empirical likelihood inference for outliers in autoregressive time series
5A. Basso and S. Funari: The role of fund size and returns to scale in the performance of mutual funds
6 M. Biancardi and G. Villani: A ro
ISBN:9783319050140
Series:eBooks
Series:SpringerLink
Series:Mathematics and Statistics (Springer-11649)
Keywords: Mathematics , Finance , Mathematical statistics
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