Fermilab Fermilab Core Computing Division

Library Home |  Ask a Librarian library@fnal.gov |  Book Catalog |  Library Journals |  Requests |  SPIRES |  Fermilab Documents |

Fermilab Library
SPIRES-BOOKS: FIND KEYWORD ONCOLOGY *END*INIT* use /tmp/qspiwww.webspi1/4553.89 QRY 131.225.70.96 . find keyword oncology ( in books using www Cover
Image
Call number:1118570901:ONLINE Show nearby items on shelf
Title:A Practical Guide to Designing Phase II Trials in Oncology
Author(s): Brown
Date:2014
Publisher:Wiley
Size:1 online resource (255 p.)
ISBN:9781118570906
Series:eBooks
Series:Wiley Online Library
Series:Wiley 2016 package purchase
Keywords: Statistics
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2016-9783319336992:ONLINE Show nearby items on shelf
Title:An Intraoperative Beta−Probe for Cancer Surgery
Author(s): Francesco Collamati
Date:2016
Size:1 online resource (24 p.)
Note:10.1007/978-3-319-33699-2
Contents:Introduction -- Radioguided Surgery -- The FLUKA Monte Carlo Code -- Design and Tests of the Probe -- Medical Applications -- Evaluation of Probe Performances -- Conclusion.
ISBN:9783319336992
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Physics , Surgical oncology , Nuclear physics , Medical physics , Radiation , Physics , Medical and Radiation Physics , Surgical Oncology , Particle and Nuclear Physics
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2016-9783319179308:ONLINE Show nearby items on shelf
Title:Physical Sciences and Engineering Advances in Life Sciences and Oncology A WTEC Global Assessment
Author(s):
Date:2016
Size:1 online resource (196 p.)
Note:10.1007/978-3-319-17930-8
Contents:Foreword -- Executive Summary -- Preface -- ToC -- List of Figures.-Chapter 1 -- Introduction -- Chapter 2 -- Complexity and Information: Cancer as a Multiscale Complex Adaptive System -- Chapter 3 -- Mimicking the Microenvironement
-- Chapter 4.- Cancer Cell Mechanics -- Chapter 5.- Fluid Mechanics and Transport in Tumors -- Chapter 6 -- The Dynamics of Cell Motility -- Chapter 7.- Devices and New Diagnostic Principles -- Chapter 8 -- Clinical Perspective --
Appendix A. APHELION Study Panelists and Advisors -- Appendix B. Site Visit Reports - Europe -- Appendix C. Site Visit Reports - Asia -- Appendix D. Site Visit Reports - United Kingdom -- Appendix E. Site Visit Reports - Brazil --
Appendix F. Recent Conferences
ISBN:9783319179308
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Physics , Oncology , Biochemistry , Biophysics , Biological physics , Medical physics , Radiation , Statistical physics , Dynamical systems , Biomedical engineering , Physics , Biophysics and Biological Physics , Oncology , Biomedical Engineering , Medical and Radiation Physics , Biochemistry, general , Statistical Physics, Dynamical Systems and Complexity
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2014-9783319072128:ONLINE Show nearby items on shelf
Title:Statistical Analysis of Next Generation Sequencing Data [electronic resource]
Author(s): Somnath Datta
Dan Nettleton
Date:2014
Publisher:Cham : Springer International Publishing : Imprint: Springer
Size:1 online resource
Note:Next Generation Sequencing (NGS) is the latest high throughput technology to revolutionize genomic research. NGS generates massive genomic datasets that play a key role in the big data phenomenon that surrounds us today. Toextract signals from high-d imensional NGS data and make valid statistical inferences and predictions, novel data analytic and statistical techniques are needed. This book contains 20 chapters written by prominent statisticians workingwith NGS data. The topics range from basic prepr ocessing and analysis with NGS data to more complex genomic applications such as copy number variation and isoform expression detection. Research statisticians who want to learn aboutthis growing and exciting area will find this book useful. In addition, many chapters from this book could be included in graduate-level classes in statistical bioinformatics for training future biostatisticians who will be expected todeal with genomic data in basic biomedical research, genomic clinical trials and personalize d medicine. About the editors: Somnath Datta is Professor and Vice Chair of Bioinformatics and Biostatistics at the University of Louisville.He is Fellow of the American Statistical Association, Fellow of the Institute of Mathematical Statistics, and Elec ted Member of the International Statistical Institute. He has contributed to numerous research areas in Statistics,Biostatistics and Bioinformatics. Dan Nettleton is Professor and Laurence H. Baker Endowed Chair of Biological Statistics in the Department of Statistics at Iowa State University. He is Fellow of the American Statistical Associationand has published research on a variety of topics in statistics, biology, and bioinformatics
Contents:Statistical Analyses of Next Generation Sequencing Data: An Overview
Using RNA
seq Data to Detect Differentially Expressed Genes
Differential Expression Analysis of Complex RNA
seq Experiments Using edgeR
Analysis of Next Generation Sequencing Data Using Integrated Nested Laplace Approximation (INLA)
Design of RNA Sequencing Experiments
Measurement, Summary, and Methodological Variation in RNA
sequencing
Functional PCA for differential expression testing with RNA
seq data
Mapping of Expression Quantitative Trait Loci using RNA
seq Data
The Role of Spike
In Standards in
ISBN:9783319072128
Series:eBooks
Series:SpringerLink
Series:Frontiers in Probability and the Statistical Sciences
Series:Mathematics and Statistics (Springer-11649)
Keywords: Statistics , Oncology , Human genetics
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2014-9783319062242:ONLINE Show nearby items on shelf
Title:Biophysical Effects of Cold Atmospheric Plasma on Glial Tumor Cells [electronic resource]
Author(s): Julia Kritzer
Date:2014
Publisher:Cham : Springer International Publishing : Imprint: Springer
Size:1 online resource
Note:Cold atmospheric plasma is an auspicious new candidate in cancer treatment. Cold atmospheric plasma (CAP) is a partially ionized gasin whichthe ion temperature is close to room temperature. It contains electrons, chargedparticles, radicals, various e xcited molecules and UV photons. These various compositional elements have the potential to inhibit cancer cell activitywhilst doing no harm tohealthy cells. Glioblastoma (GBM) is the most common andlethal primary brain tumor in adults treatment including surgery, radio- and chemotherapy remains palliative for most patients as a cureremains elusive. The successful combination of the standard chemotherapeutic temozolomide (TMZ)and CAP treatment features synergistic effects even in resistant glioma cells. I n particular in glioma therapy, CAP could offer an innovative approach allowing specific cancer cell / tumor tissue inhibition without damaging healthycells. Thus CAP is a promising candidate for combination therapy especially for patients suffering from GBMs showing TMZ resistance
Contents:Summary
Introduction
Materials and Methods
Results
Discussion
Assessment and Outlook
Supplementary Data
References
ISBN:9783319062242
Series:eBooks
Series:SpringerLink
Series:Springer Theses, Recognizing Outstanding Ph.D. Research, 2190-5053
Series:Physics and Astronomy (Springer-11651)
Keywords: Oncology
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2014-9781461488996:ONLINE Show nearby items on shelf
Title:Hadron Therapy Physics and Simulations [electronic resource]
Author(s): Marcos dvila Nunes
Date:2014
Publisher:New York, NY : Springer New York : Imprint: Springer
Size:1 online resource
Note:This brief provides an in-depth overview of the physics of hadron therapy, ranging from the history to the latest contributions to the subject. It covers the mechanisms of protons and carbon ions at the molecular level (DNA breaksand proteins 53BP1 a nd RPA), the physics and mathematics of accelerators (Cyclotron and Synchrotron), microdosimetry measurements (with new results so far achieved), and Monte Carlo simulations in hadron therapy using FLUKA (CERN) andMCHIT (FIAS) software. The text also incl udes information about proton therapy centers and carbon ion centers (PTCOG), as well as a comparison and discussion of both techniques in treatment planning and radiation monitoring. This briefis suitable for newcomers to medical physics as well as seaso ned specialists in radiation oncology
Contents:Brief History of Radiotherapy
Time line of Hadron Therapy
Mechanism of Hadron Therapy at molecular level
Strengthening concepts about variations in therapy by radiation
Which conditions can be treated by Hadron Therapy?
Hospitals and Research Centers for cancer treatment by Hadron
Particle therapy facilities in operation (incl. patient statistics)
Tumors: localization
Using boro
therapy to treat tumors
Which therapy must be used? Where? Conduct before and during treatment used at HIT
After Modern Radiotherapy: estimating risk of second malignancies
Particles a
ISBN:9781461488996
Series:eBooks
Series:SpringerLink
Series:SpringerBriefs in Physics, 2191-5423
Series:Physics and Astronomy (Springer-11651)
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2014-9781461483045:ONLINE Show nearby items on shelf
Title:The Phantoms of Medical and Health Physics [electronic resource] : Devices for Research and Development
Author(s): Larry A DeWerd
Michael Kissick
Date:2014
Publisher:New York, NY : Springer New York : Imprint: Springer
Size:1 online resource
Note:Acomprehensive overview of all types of phantoms used in medical imaging, therapy, nuclear medicine and health physics is provided in this title. For ionizing radiation, dosimetry with respect to issues of material composition,shape, and motion/posit ion effects are all highlighted. For medical imaging, each type of technology will need specific materials and designs, and the physics and indications will be explored for each type. Health physics phantoms areconcerned with some of the same issues such as material heterogeneity, but also unique issues such as organ-specific radiation dose from sources distributed in other organs. Though some of the information enclosed is found in othersources, divided especially along the three categories of imaging, t herapy, and health physics, many medical physicists as well as professionals need to bridge these three catagories. Readers will be able to use this book to select theappropriate phantom from a vendor at a clinic, to learn from as a student, to choose mat erials for custom phantom design, to design dynamic features, and as a reference for a variety of applications
Contents:1. Introduction to Phantoms of Medical and Health Physics
Section I: Phantoms of Radiation Therapy
2. Radiation Therapy Dosimetry Phantoms
3. Anthropormorphic Phantoms for Radiation Oncology Medical Physics
4. Motion Phantoms for Therapy
5. Phantoms in Brachytherapy
Section II. Imaging Phantoms
6. Imaging Phantoms: Conventional X
ray Imaging Applications
7. Computer Tomography (CT) Phantom Applications
8. Mammography Phantoms
9. Phantoms for Ultrasound Experimentation and Quality Control
10. Phantoms for Magnetic Resonance Imaging
11. Nuclear Medicine phanto
ISBN:9781461483045
Series:eBooks
Series:SpringerLink
Series:Biological and Medical Physics, Biomedical Engineering, 1618-7210
Series:Physics and Astronomy (Springer-11651)
Keywords: Radiology, Medical , Nuclear medicine , Diagnosis, Ultrasonic , Biomedical engineering
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2013-9781461449249:ONLINE Show nearby items on shelf
Title:Cobalt Blues [electronic resource] : The Story of Leonard Grimmett, the Man Behind the First Cobalt-60 Unit in the United States
Author(s): Peter R Almond
Date:2013
Publisher:New York, NY : Springer New York : Imprint: Springer
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:For the latter half of the 20th century, cobalt-60 units were the mainstay of radiation treatments for cancer. Cobalt Blues describes the development of the first cobalt-60 unit in the United States and the man behind it, LeonardGrimmett. Conceptuall y conceived before World War II, it only became possible because of the development of nuclear reactors during the war. Although Grimmett conceived of and published his ideas first, the Canadians built the firstunits because of the capability of their rea ctor to produce more suitable cobalt-60 sources. This book tells the story of how Grimmett and others came together at the time that the U S Atomic Energy Agency was pushing the use ofradioactivity in medicine. Due to his sudden death, very little informa tion about Grimmett was known until recently, when various documents have come to light, allowing the full story to be told
Note:Springer eBooks
Contents:Foreword
Prologue
M.D. Anderson Cancer Center 1941
1946
The Journey, January 29 to February 7, 1949
Early Life and Education, London 1903
1929
Medical Physicist Part I, London 1929
1944
The Unknown Years and UNESCO Paris, 1944
1948
Replacing Radium 1937
1949
Arrival, Houston February 1949
The Cobalt Unit 1949
1954
Medical Physicist Part II, Houston 1949
1951
Cobalt
60 and the Notebook
Cobalt
60 in Perspective
Epilogue: Grimmett the Man
Appendix A: Principles of Radiotherapy
Appendix B: Principles of Reactor Production of Cobalt
60
Appendix C: Gri
ISBN:9781461449249
Series:e-books
Series:SpringerLink (Online service)
Series:Physics and Astronomy (Springer-11651)
Keywords: Science History , Oncology , Radiology, Medical
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2012-9783642214141:ONLINE Show nearby items on shelf
Title:Ion Beam Therapy [electronic resource] : Fundamentals, Technology, Clinical Applications
Author(s): Ute Linz
Date:2012
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:The book provides a detailed, up-to-date account of the basics, the technology, and the clinical use of ion beams for radiation therapy. Theoretical background, technical components, and patient treatment schemes are delineated bythe leading experts that helped to develop this field from a research niche to its current highly sophisticated and powerful clinical treatment level used to the benefit of cancer patients worldwide. Rather than being a side-by-sidecollection of articles, this book consists of related chapters. It is a common achievement by 76 experts from around the world. Their expertise reflects the diversity of the field with radiation therapy, medical and acceleratorphysics, radiobiology, computer science, engineering, and health econom ics. The book addresses a similarly broad audience ranging from professionals that need to know more about this novel treatment modality or consider to enter thefield of ion beam therapy as a researcher. However, it is also written for the interested publ ic and for patients who might want to learn about this treatment option
Note:Springer eBooks
Contents:Ion Beam Therapy in Perspective
Physical and Biological Aspects
Models and Preclinical Studies
Clinical Results and Indications
Beam Preparation and Control
Patient Positioning and Treatment Planning
Individual Facilities and Management Issues
Future Developments
ISBN:9783642214141
Series:e-books
Series:SpringerLink (Online service)
Series:Biological and Medical Physics, Biomedical Engineering, 1618-7210 : v320
Series:Physics and Astronomy (Springer-11651)
Keywords: Oncology , Nuclear medicine , Radiotherapy , Biomedical engineering
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2011-9789400702479:ONLINE Show nearby items on shelf
Title:Radiation Protection in Medical Physics [electronic resource]
Author(s): Yves Lemoigne
Alessandra Caner
Date:2011
Publisher:Dordrecht : Springer Netherlands
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:This book introduces the fundamental aspects of Radiation Protection in Medical Physics and covers three main themes: General Radiation Protection Principles Radiobiology Principles Radiation Protection in Hospital MedicalPhysics. Each of these topic s is developed by analysing the underlying physics principles and their implementation, quality and safety aspects, clinical performance and recent advances in the field. Some issues specific to theindividual techniques are also treated, e.g. calculation of patient dose as well as that of workers in hospital, optimisation of equipment used, shielding design of radiation facilities, radiation in oncology such as use ofbrachytherapy in gynecology or interventional procedures. All topics are presented with d idactical language and style, making this book an appropriate reference for students and professionals seeking a comprehensive introduction to thefield as well as a reliable overview of the most recent developments
Note:Springer eBooks
Contents:Preface. List of Participants. Photographs. General Radiation Protection Principles. Internal Safety Standards
Radiation Units, Limits & Dose Constraints
Radiobiology Principles. Molecular Aspects of Radiation Biology
Radiobiology in Radiotherapy
Radiation Protection Application in Hospital Medical Physics. General Principles of Risk Assessment for Ionising Radiation
Radiation Protection of the Workers and the Public from Exposed Patients
Installation Shielding in Diagnostic Radiology and Computed Tomography
Acceptability Criteria, Justification and Ethical Issues in Using
ISBN:9789400702479
Series:e-books
Series:SpringerLink (Online service)
Series:NATO Science for Peace and Security Series B: Physics and Biophysics, 1874-6500 : v1
Series:Physics and Astronomy (Springer-11651)
Keywords: Environmental sciences , Radiology, Medical , Interventional radiology , Nuclear medicine , Radiotherapy , Oncology , Environmental protection
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2010-9783642156038:ONLINE Show nearby items on shelf
Title:The Role of Model Integration in Complex Systems Modelling [electronic resource] An Example from Cancer Biology
Author(s): Manish Patel
Sylvia Nagl
Date:2010
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Model integration the process by which different modelling efforts can be brought together to simulate the target system is a core technology in the field of Systems Biology. In the work presented here model integrationwas addressed directly taking cancer systems as an example. An in-depth literature review was carried out to survey the model forms and types currently being utilised. This was used to formalise the main challenges that modelintegration poses, namely that of paradigm (the formalism o n which a model is based), focus (the real-world system the model represents) and scale. A two-tier model integration strategy, including a knowledge-driven approach to addressmodel semantics, was developed to tackle these challenges. In the first step a novel description of models at the level of behaviour, rather than the precise mathematical or computational basis of the model, is developed by distillinga set of abstract classes and properties. These can accurately describe model behaviour and hence de scribe focus in a way that can be integrated with behavioural descriptions of other models. In the second step this behaviour isdecomposed into an agent-based system by translating the models into local interaction rules. The book provides a detailed and highly integrated presentation of the method, encompassing both its novel theoretical and practical aspects,which will enable the reader to practically apply it to their model integration needs in academic research and professional settings. The text is s elf-supporting. It also includes an in-depth current bibliography to relevant researchpapers and literature. The review of the current state of the art in tumour modelling provides added value
Note:Springer eBooks
Contents:Part 1 Introduction
Part 2 Nature to Numbers: Complex Systems Modelling of Cancer
Part 3 Coping with Complexity: Modelling of Complex Systems
Part 4 Complexity and Model Integration: Formalisations
Part 5 Novel Strategies for Integrating Models into Systems
level Simulations
Part 6 Experiments in Model Integration
Part 7 Discussion
ISBN:9783642156038
Series:e-books
Series:SpringerLink (Online service)
Series:Understanding Complex Systems, 1860-0832
Series:Physics and Astronomy (Springer-11651)
Keywords: Engineering , Oncology , Biological models
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2010-9781441915863:ONLINE Show nearby items on shelf
Title:Fundamentals of Clinical Trials [electronic resource]
Author(s): Lawrence M Friedman
Curt D Furberg
David L DeMets
Date:2010
Edition:Fourth
Publisher:New York, NY : Springer New York : Imprint: Springer
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:This is the fourth edition of a very successful textbook on clinical trials methodology, written by three recognized experts who have long and extensive experience in all areas of clinical trials. Most chapters have been revisedconsiderably from the third edition. A chapter on ethics has been added and topics such as noninferiority and adaptive designs now receive considerable discussion. There is much new material on adverse events, adherence, datamonitoring, and issues in analysis. This book is int ended for the clinical researcher who is interested in designing a clinical trial and developing a protocol. It is also of value to researchers and practitioners who must criticallyevaluate the literature of published clinical trials and assess the merits of each trial and the implications for the care and treatment of patients. The authors use numerous examples of published clinical trials from a variety ofmedical disciplines to illustrate the fundamentals. The text is organized sequentially from definin g the question to trial closeout. One chapter is devoted to each of the critical areas to aid the clinical trial researcher. These areasinclude pre-specifying the scientific questions to be tested and appropriate outcome measures, determining the organiza tional structure, estimating an adequate sample size, specifying the randomization procedure, implementing theintervention and visit schedules for participant evaluation, establishing an interim data and safety monitoring plan, detailing the final analysi s plan, and reporting the trial results according to the pre-specified objectives.Although a basic introductory statistics course is helpful in maximizing the benefit of this book, a researcher or practitioner with limited statistical background would sti ll find most if not all the chapters understandable andhelpful. While the technical material has been kept to a minimum, the statistician may still find the principles and fundamentals presented in this
Note:Springer eBooks
Contents:Introduction to clinical trials
Ethical issues
What is the question?
Study population
Basic study design
The randomization process
Blindness
Sample size
Baseline assessment
Recruitment of study participants
Data collection and quality control
Assessing and reporting adverse effects
Assessment of health
related quality of life
Participant adherence
Survival analysis
Monitoring response variables
Issues in data analysis
Closeout
Reporting and interpreting of results
Multicenter trials
ISBN:9781441915863
Series:e-books
Series:SpringerLink (Online service)
Series:Mathematics and Statistics (Springer-11649)
Keywords: Statistics , Oncology , Public health , Epidemiology
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2010-9781441915726:ONLINE Show nearby items on shelf
Title:Statistical Methods for Disease Clustering [electronic resource]
Author(s): Toshiro Tango
Date:2010
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:The development of powerful computing environment and the geographical information system (GIS) in recent decades has thrust the analysis of geo-referenced disease incidence data into the mainstream of spatial epidemiology. Thisbook offers a modern p erspective on statistical methods for detecting disease clustering, an indispensable procedure to find a statistical evidence on aetiology of the disease under study. With increasing public health concerns aboutenvironmental risks, the need for sophistica ted methods for analyzing spatial health events is immediate. Furthermore, the research area of statistical methods for disease clustering now attracts a wide audience due to the perceivedneed to implement wide-ranging monitoring systems to detect possibl e health-related events such as the occurrence of the severe acute respiratory syndrome (SARS), pandemic influenza and bioterrorism As an invaluable resource for a widerange of audience including public health researchers, epidemiologists and biostatistia ns, this book features: A concise introduction to basic concepts of disease clustering/clusters A historical overview of methods for diseaseclustering A detailed treatment of selected methods useful for practical investigation of disease clustering Analys is and illustration of methods for a variety of real data sets Toshiro Tango, Ph.D., is the Director of Department ofTechnology Assessment and Biostatistics of National Institute of Public Health, Japan. He has published a number of methodological and app lied articles on various aspects of biostatistics. He is Past President of the Japanese Region ofthe International Biometric Society. He has served as Associate Editor for several journals including Statistics in Medicine and Biometrics
Note:Springer eBooks
Contents:Introduction
Clustering and clusters
Disease mapping: Visualization of spatial clustering
Tests for temporal clustering
General tests for spatial clustering: Regional count data
General tests for spatial clustering: Case
control point data
Tests for space
time clustering
Focused tests for spatial clustering
Space
time scan statistics
ISBN:9781441915726
Series:e-books
Series:SpringerLink (Online service)
Series:Statistics for Biology and Health, 1431-8776
Series:Mathematics and Statistics (Springer-11649)
Keywords: Statistics , Oncology , Epidemiology , Biometrics , Statistical methods
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2009-9789048130979:ONLINE Show nearby items on shelf
Title:Radiotherapy and Brachytherapy [electronic resource]
Author(s): Yves Lemoigne
Alessandra Caner
Date:2009
Publisher:Dordrecht : Springer Netherlands
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:This volume collects a series of lectures presented at the tenth ESI School held at Archamps (FR) in November 2007 and dedicated to radiotherapy and brachytherapy. The lectures focus on the multiple facets of radiotherapy ingeneral, including externa l radiotherapy (often called teletherapy) as well as internal radiotherapy (called brachytherapy). Radiotherapy strategy and dose management as well as the decisive role of digital imaging in the associatedclinical practice are developed in several articl es. Grouped under the discipline of Conformal Radiotherapy (CRT), numerous modern techniques, from Multi-Leaf Collimators (MLC) to Intensity Modulated RadioTherapy (IMRT), are explainedin detail. The importance of treatment planning based upon patient dat a from digital imaging (Computed Tomography) is also underlined. Finally, despite the quasi- totality of patients being presently treated with gamma and X-rays,novel powerful tools are emerging using proton and light ions (like carbon ions) beams, bound t o become more and more important in patient treatment. These technological developments, going under the comprehensive name ofHadrontherapy, are presented here with special focus on the rational and state of the art of the field. All topics are presented with didactical language and styles, making this book an appropriate reference for students andprofessionals seeking a comprehensive introduction to the field as well as a reliable outlook on the most recent developments
Note:Springer eBooks
Contents:Preface. List of participants. Photographs. I: Introduction To Radiotherapy. Fundamental Radiobiology and its Application to Radiation Oncology
Accuracy Strategies in Radiotherapy
2: X
Rays Teletherapy. Dosimetry for Photons and Electrons Radiation
Nomenclature in Radiotherapy
Quality Assurance in Radiotherapy
Radiotherapy Accidents
Clinical Applications of 3
D Conformal Radiotherapy
Treatment Planning: IMRT Optimization
Basic and Advanced Techniques
Treatment Planning: Stereotactic Treatment Techniques
Image Guided Radiotherapy
Clinical Use of 3
D Image Registration
ISBN:9789048130979
Series:e-books
Series:SpringerLink (Online service)
Series:NATO Science for Peace and Security Series B: Physics and Biophysics, 1874-6500
Series:Physics and Astronomy (Springer-11651)
Keywords: Radiology, Medical , Nuclear medicine , Biomedical engineering
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2009-9780387781938:ONLINE Show nearby items on shelf
Title:Cancer Mortality and Morbidity Patterns in the U.S. Population [electronic resource] : An Interdisciplinary Approach
Author(s): K.G Manton
Igor Akushevich
Julia Kravchenko
Date:2009
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:This book is the first of its kind to describe interdisciplinary approaches to biomedical studies. It views analyses of biomedical data sets, such as cancer morbidity and mortality, from a different and richer than classicepidemiological perspective by using mathematical modeling methods, including ones providing insights into probable mechanisms of human carcinogenesis. The book will be useful for many specialists, e.g., epidemiologists, oncologists,medical researchers, biologists, public health and environmental specialists, and specialists in mathematical modeling. Medical, biology and math undergraduates and postgraduates, as well as basic and applied researchers attempting toextend their studies in collaboration with other specialists in interdi sciplinary teams, will find practical information here. Biomedical specialists could be interested in historical aspects of cancer treatment and prevention,mechanisms of carcinogenesis, cancer risk factors, cancer mortality and morbidity trends in the U.S . over a more than 50-year period, as well as specific features of cancer histotypes, and recent approaches to cancer prevention.Readers interested in analytic aspects can find information on existing and innovative approaches used in interdisciplinary st udies such as stochastic process models, microsimulation of interventions, and empirical Bayes approaches.This book was written by authors with different backgrounds who teamed in an interdisciplinary group. Kenneth G. Manton, Ph.D. (Demography) is Resear ch Professor of Demographic Studies at Duke University (Durham, NC). He was Head ofthe W.H.O. Collaborating Center for Research and Training in the Methods of Assessing Risk and Forecasting Health Status Trends. He has authored more than 450 peer-reviewed publications, including several books. Igor Akushevich, Ph.D.(Theoretical and Mathematical Physics), Center for Population Health and Aging at Duke University, authored more than 70 peer-reviewed publi
Note:Springer eBooks
Contents:Preface
Introduction: Cancer contra human: cohabitation with casualties?
Cancer modeling: how far can we move?
Cancer risk factors
Standard and innovative statistical methods for empirically analyzing cancer morbidity and mortality
Stochastic methods of analysis
U.S. cancer morbidity and mortality risks
U.S. cancer morbidity: modeling age
patterns of cancer histotypes
Risk factors intervention
Cancer prevention
Conclusion/outlook
Appendices
ISBN:9780387781938
Series:e-books
Series:SpringerLink (Online service)
Series:Statistics for Biology and Health, 1431-8776
Series:Mathematics and Statistics (Springer-11649)
Keywords: Statistics , Oncology , Epidemiology , Bioinformatics , Demography
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2008-9782287339110:ONLINE Show nearby items on shelf
Title:Gntique statistique [electronic resource]
Author(s): Stephan Morgenthaler
Date:2008
Publisher:Paris : Springer Paris
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Cet ouvrage expose les principaux outils statistiques utiles la gntique : tests de signification, mthodes danalyse fondes sur la fonction de vraisemblance, algorithme EM, modlisations, analyse de la variance,classifications hirarchiques, comparaison s multiples, etc. Tous permettent dclairer nombre de phnomnes biologiques comme la carcinogense, la gntique des populations, lquilibre de Hardy-Weinberg, la slectionnaturelle, les mutations, lhrdit, les processus de coalescence, ou encore lvolution. Ce li vre sadresse autant aux mathmaticiens quaux biologistes. Rdig avec un grand souci de clart, il est galementaccessible aux non-spcialistes qui pourront, grce lui, renforcer leur base thorique et surtout dvelopper leur savoir-faire par des applications trs concrtes
Note:Springer eBooks
ISBN:9782287339110
Series:e-books
Series:SpringerLink (Online service)
Series:Statistique et probabilits appliques
Series:Mathematics and Statistics (Springer-11649)
Keywords: Statistics , Oncology , Epidemiology , Genetics Mathematics , Biology Mathematics , Distribution (Probability theory)
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2008-9781402069529:ONLINE Show nearby items on shelf
Title:Optical Waveguide Sensing and Imaging [electronic resource]
Author(s): Wojtek J Bock
Israel Gannot
Stoyan Tanev
Date:2008
Publisher:Dordrecht : Springer Netherlands
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:The book explores various aspects of existing and emerging fiber and waveguide optics sensing and imaging technologies including recent advances in nanobiophotonics. The focus is both on fundamental and applied research as well ason applications in c ivil engineering, biomedical sciences, environment, security and defence. The main goal of the multi-disciplinarry team of Editors was to provide an useful reference of state-of-the-art overviews covering a varietyof complementary topics on the interface of engineering and biomedical sciences
Note:Springer eBooks
ISBN:9781402069529
Series:e-books
Series:SpringerLink (Online service)
Series:NATO Science for Peace and Security Series, 1874-6500
Series:Physics and Astronomy (Springer-11651)
Keywords: Oncology , Biomedical engineering , Environmental toxicology , Biotechnology
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2008-9780817647131:ONLINE Show nearby items on shelf
Title:Selected Topics in Cancer Modeling [electronic resource] : Genesis, Evolution, Immune Competition, and Therapy
Author(s): Elena Angelis
Mark A. J Chaplain
Nicola Bellomo
Date:2008
Publisher:Boston : Birkhuser Boston
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:A major challenge in the modeling and simulation of tumor growth is the mathematical description of living matter, which is far more complex than a mathematical description of inert matter. One critical piece of this challenge iscreating multiscale m odels that take into account subcellular, cellular, and macroscopic levels of cancer. The complexity of these different levels requires the development of new mathematical methods and ideas, which are examined inthis work. Written by first-rate researcher s in the field of mathematical biology, this collection of selected chapters offers a comprehensive overview of state-of-the-art mathematical methods and tools for modeling and analyzingcancer phenomena. Topics covered include: * Genetic and epigenetic pa thways to colon cancer * A game theoretical perspective on the somatic evolution of cancer * Nonlinear modeling and simulation of tumor growth * Tumor cords and theirresponse to anticancer agents * Modeling diffusely invading brain tumors * Multiphase mod els of tumor growth * Mathematical modeling of breast carcinogenesis * Predictive models in tumor immunology * Multiscale modeling of solid tumorgrowth Selected Topics in Cancer Modeling is an excellent reference for researchers, practitioners, and gradua te students in applied mathematics, mathematical biology, and related fields. The book has an overall aim of quantitative,predictive mathematical modeling of solid tumor growth at all scales, from genetics all the way through to treatment therapy for pati ents
Note:Springer eBooks
Contents:Preface
List of Contributors
Genetic and Epigenetic Pathways to Colon Cancer: Relating Experimental Evidence with Modeling
From Kinetic Theory for Active Particles to Modelling Immune Competition
Towards Microscopic and Nonlocal Models of Tumour Invasion of Tissue
Nonlinear Renewal Equations
A Game Theoretical Perspective on the Somatic Evolution of Cancer
Nonlinear Modeling and Simulation of Tumor Growth
Tumour Cords and Their Response to Anticancer Agents
Modeling Diffusely Invading Brain Tumors: An Individualized Approach to Quantifying Glioma Evolution and Respon
ISBN:9780817647131
Series:e-books
Series:SpringerLink (Online service)
Series:Modeling and Simulation in Science, Engineering and Technology
Series:Mathematics and Statistics (Springer-11649)
Keywords: Mathematics , Oncology , Biology Mathematics , Physiology Mathematics
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2008-9780387728353:ONLINE Show nearby items on shelf
Title:The Frailty Model [electronic resource]
Author(s): Luc Duchateau
Paul Janssen
Date:2008
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Clustered survival data are encountered in many scientific disciplines including human and veterinary medicine, biology, epidemiology, public health and demography. Frailty models provide a powerful tool to analyse clusteredsurvival data. In contrast to the large number of research publications on frailty models, relatively few statistical software packages contain frailty models. It is demanding for statistical practitioners and graduate students tograsp a good knowledge on frailty models from the e xisting literature. This book provides an in-depth discussion and explanation of the basics of frailty model methodology for such readers. The discussion includes parametric andsemiparametric frailty models and accelerated failure time models. Common tech niques to fit frailty models include the EM-algorithm, penalised likelihood techniques, Laplacian integration and Bayesian techniques. More advanced frailtymodels for hierarchical data are also included. Real-life examples are used to demonstrate how part icular frailty models can be fitted and how the results should be interpreted. The programs to fit all the worked-out examples in thebook are available from the Springer website with most of the programs developed in the freeware packages R and Winbugs. T he book starts with a brief overview of some basic concepts in classical survival analysis, collecting what isneeded for the reading on the more complex frailty models. Luc Duchateau is Associate Professor of Statistics at the Faculty of Veterinary Medici ne of the Ghent University, Belgium. He is board member of the Quetelet Society (BelgianRegion of the International Biometric Society) and of the International Biometric Society Channel Network. He has collaborated extensively with physicians in oncology and allergy, public health workers and veterinarians, and is anauthor of numerous papers in statistical, medical and veterinarian journals. Paul Janssen is Professor of Statistics at the Centre for Stat
Note:Springer eBooks
Contents:Parametric proportional hazards models with gamma frailty
Alternatives for the frailty model
Frailty distributions
The semiparametric frailty model
Multifrailty and multilevel models
Extensions of the frailty model
ISBN:9780387728353
Series:e-books
Series:SpringerLink (Online service)
Series:Mathematics and Statistics (Springer-11649)
Keywords: Statistics , Oncology , Emerging infectious diseases , Epidemiology , Computer simulation , Biometrics
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2008-9780387726458:ONLINE Show nearby items on shelf
Title:Radiation Oncology: A Physicist's-Eye View [electronic resource]
Author(s): Michael Goitein
Date:2008
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Springer eBooks
ISBN:9780387726458
Series:e-books
Series:SpringerLink (Online service)
Series:Biological and Medical Physics, Biomedical Engineering, 1618-7210
Series:Physics and Astronomy (Springer-11651)
Keywords: Oncology , Biomedical engineering
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2007-9781402064661:ONLINE Show nearby items on shelf
Title:Supramolecular Structure and Function 9 [electronic resource]
Author(s): Greta Pifat-Mrzljak
Date:2007
Publisher:Dordrecht : Springer Netherlands
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:The book is based on International Summer Schools on Biophysics held in Croatia which, contrary to other workshops centered mainly on one topic or technique, has very broad scope providing advanced training in areas related tobiophysics. This volume is presenting papers in the field of biophysics for studying biological phenomena by using physical methods (NMR, EPR, FTIR, Mass Spectrometry, etc.) and/or concepts (predictions of protein-protein interactions,virtual ligand screening etc.). The interrel ationship of supramolecular structures and there functions is enlightened by applications of principals of these physical methods in the biophysical and molecular biology context
Note:Springer eBooks
Contents:Predictions of Protein
Protein Interactions at the Atomic Scale
An Infrared Study of Fibril Formation in Insulin from Different Sources
Some Basic Biomolecular NMR for Protein Structure Determination
Solid State NMR for Studying Membrane Proteins
Protein Complexes in SUMO Signaling
Mass Spectrometry and Glycomics
Mechanisms of Supramolecular Assembly Exemplified by Microtubules and Amyloid Fibril Formation
Hepatitis B Virus (HBV): The Life
cycle and Assembly of a Complex Virus
Photo
oxidative Stress in the Presence of a Water
soluble Derivative of C60: ESR and AFM Assay
ISBN:9781402064661
Series:e-books
Series:SpringerLink (Online service)
Series:Physics and Astronomy (Springer-11651)
Keywords: Oncology , Bioinformatics
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2006-9781402037306:ONLINE Show nearby items on shelf
Title:Ultraviolet Radiation in the Solar System [electronic resource]
Author(s): M Vzquez
A Hanslmeier
Date:2006
Publisher:Dordrecht : Springer Netherlands
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:UV radiation is an important part in the electromagnetic spectrum since the energy of the photons is great enough to produce important chemical reactions in the atmospheres of planets and satellites of our Solar System, therebyaffecting the transmiss ion of this radiation to the ground and its physical properties. Scientists have used different techniques (balloons and rockets) to access to the information contained in this radiation, but the pioneering ofthis new frontier has not been free of dangers . The Sun is our main source of UV radiation and its description occupies the first two chapters of the book. The Earth is the only known location where life exists in a planetary systemand therefore where the interaction of living organism with UV radiat ion can be tested through different epochs and on distinct species. The development of the human technology has affected the natural shield of ozone that protectscomplex lifeforms against damaging UV irradiation. The formation of the ozone hole and its co nsequences are described, together with the possible contribution of UV radiation to recent climate changes. Finally, we will discuss thepotential role of ultraviolet light in the development of life on bodies such as Mars, Europa and Titan. The Solar Sys tem is not isolated other external sources can contribute to the enhancement of the UV radiation in our environment.The influence of such events as nearby supernovae and gamma-ray bursts are described, together with the consequences to terrestrial life fr om such events
Note:Springer eBooks
Contents:Historical Introduction
Solar Ultraviolet Radiation and Magnetism
The Solar UV Variability
Atmospheric Effects of Ultraviolet Radiation
UV Radiation, Ozone and Life
UV Fluxes on Other Bodies of the Solar System
Ultraviolet Transitory Events and Life
ISBN:9781402037306
Series:e-books
Series:SpringerLink (Online service)
Series:Astrophysics and Space Science Library : v331
Series:Physics and Astronomy (Springer-11651)
Keywords: Oncology , Astronomy , Astrophysics , Astrobiology , Climatic changes , Environmental protection
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2006-9780387358512:ONLINE Show nearby items on shelf
Title:Universality of Nonclassical Nonlinearity [electronic resource] : Applications to Non-Destructive Evaluations and Ultrasonic
Author(s): Pier Paolo Delsanto
Date:2006
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:This book comes as a result of the research work developed in the framework of two international projects: the European Science Foundation supported program NATEMIS (Nonlinear Acoustic Techniques for Micro-Scale DamageDiagnostics) and a Los Alamos-ba sed international network. The main topics of both the programs and the book cover the phenomenology, theory and applications of Nonclassical Nonlinearity (NCNL). NCNL techniques have been found inrecent years to be extremely powerful (up to 1000 times mo re than the corresponding linear techniques) in a wide range of applications, including Material Characterization, Ultrasonics, Geophysics and Maintenance and Restoration ofartifacts. These techniques are being adopted as the main inspection and research tool in another European program: AERONEWS (Health monitoring of aircraft by nonlinear elastic wave propagation). In the future, the proposedUniversality of NCNL is expected to extend the range of applications to numerous other fields and scientific disci plines outside acoustics and NDE
Note:Springer eBooks
Contents:Towards a top
down approach in materials science
Nonlinear dynamical systems in economics
Nonlinearity in medical sciences (oncology)
Nonlinearity as a structural feature of living systems
Nonlinearity and complexity in Elastic Wave Motion
The state of the art of nonlinear elasticity in geomaterials
Nonlinear Rock Mechanics Seasonality and Harvesting, Revisited
Cancer growth is a nonclassical nonlinear phenomenon
Multiscale Approach to Nonlinear and Hysteretic Elastodynamics in one
and two
dimensions
Inverse modelling of microdamage characteristics in specimens of s
ISBN:9780387358512
Series:e-books
Series:SpringerLink (Online service)
Series:Physics and Astronomy (Springer-11651)
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2006-9780387337067:ONLINE Show nearby items on shelf
Title:Dose Finding in Drug Development [electronic resource]
Author(s): Naitee Ting
Date:2006
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:When you go to the pharmacy and fill a prescription, have you ever wondered if the dose of the medication is right for you? Can the dose be too low so that the drug will not work? Can the dose be too high that it may cause somepotential problem? How do people learn about dosing information? This book answers some of these questions. Dosing information on the drug label is based on discussion and agreement between the pharmaceutical manufacturer and the drugregulatory agency. A drug label is a high le vel summary of results obtained from many scientific experiments. Scientists with biological, chemical, medical, or statistical background working in the pharmaceutical industry designed andexecuted these experiments to obtain information to help understa nd the dosing information. This book introduces the drug development process, the design and analysis of clinical trials. Many of the discussions are based onapplications of statistical methods in the design and analysis of dose response studies. Although the book is prepared mainly for statisticians/biostatisticians, it also serves as a useful reference to a variety of professionalsworking for the pharmaceutical industry. The potential readers include pharmacokienticists, clinical scientists, clinical ph armacologists, pharmacists, project managers, pharmaceutical scientists, clinicians, programmers, datamanagers, regulatory specialists, and study report writers. This book is also a good reference for professionals working in a drug regulatory environment , for example, the FDA. Scientists and/or reviewers from both U.S. and foreigndrug regulatory agencies can benefit greatly from this book. In addition, statistical and medical professionals in academia may find this book helpful in understanding the drug development process and practical concerns in selectingdoses for a new drug. Naitee Ting received his Ph. D. in statistics from Colorado State University in 1987 and joined Pfizer Research right after o
Note:Springer eBooks
Contents:Introduction And New Drug Development Process
Dose Finding Based on Pre
Clinical Studies (David Salsburg)
Dose
Finding Studies in Phase I and Estimation of Maximally Tolerated Dose
Dose
Finding In Oncology Non
Parametric Methods
Dose Response in Oncology Parametric Methods
Dose Response
Pharmacokinetic
Pharmacodynamic Approach
General Considerations in Dose Response Study Designs
Clinical Trial Simulation A Case Study Incorporating Efficacy and Tolerability Dose Response
Analysis of Dose Response Studies Emax Model
Analysis of Dose Response Studies
ISBN:9780387337067
Series:e-books
Series:SpringerLink (Online service)
Series:Statistics for Biology and Health, 1431-8776
Series:Mathematics and Statistics (Springer-11649)
Keywords: Statistics , Toxicology
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2006-9780387254449:ONLINE Show nearby items on shelf
Title:Quantitative Analysis in Nuclear Medicine Imaging [electronic resource]
Author(s): Habib Zaidi
Date:2006
Publisher:Boston, MA : Springer US
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:This book provides a review of image analysis techniques as they are applied in the field of diagnostic and therapeutic nuclear medicine. Driven in part by the remarkable increase in computing power and its ready and inexpensiveavailability, this is a relatively new yet rapidly expanding field. Likewise, although the use of radionuclides for diagnosis and therapy has origins dating back almost to the discovery of natural radioactivity itself, radionuclidetherapy and, in particular, targeted radionucl ide therapy has only recently emerged as a promising approach for therapy of cancer and, to a lesser extent, other diseases. As effort has, therefore, been made to place the reviewsprovided in this book in a broader context. The effort to do this is refle cted by the inclusion of introductory chapters that address basic principles of nuclear medicine imaging, followed by overview of issues that are closely relatedto quantitative nuclear imaging and its potential role in diagnostic and therapeutic applicati ons. The different chapters discuss the basic principles and various steps required for obtaining quantitatively accurate data from nuclearmedicine images including data collection methods and algorithms used to correct them for physical degrading factors (e.g. collimator response, attenuation, scatter, partial volume effect), and image reconstruction algorithms(analytic, iterative) as well as image processing and analysis techniques as their clinical and research applications in neurology, cardiology and oncology. Some algorithms are described and illustrated with some useful features andclinical applications. Other potential applications of quantitative image analysis such as image-guided radiation therapy are also discussed
Note:Springer eBooks
Contents:Preface
Overview of nuclear medical imaging: physics and instrumentation
Dual
modality imaging: more than the sum of its parts
Analytic image reconstruction methods
Iterative image reconstruction methods
Collimator
detector response compensation in SPECT
Attenuation correction strategies in emission tomography
Scatter correction strategies in emission tomography
Correction of partial volume effects in emission tomography
Image registration techniques in nuclear medicine imaging
Image segmentation techniques in nuclear medicine imaging
Monte Carlo modeling in nucl
ISBN:9780387254449
Series:e-books
Series:SpringerLink (Online service)
Series:Physics and Astronomy (Springer-11651)
Keywords: Neurosciences , Toxicology , Cardiology , Oncology , Biomedical engineering
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2005-9781402028854:ONLINE Show nearby items on shelf
Title:The Science of Phototherapy: An Introduction [electronic resource]
Author(s): Leonard I Grossweiner
James B Grossweiner
B.H Gerald Rogers
Linda R Jones
Date:2005
Publisher:Dordrecht : Springer Netherlands
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Phototherapy exemplifies scientific medicine. The major advances have resulted from effective collaborations between basic researchers and clinicians. This book is directed to clinicians and basic researchers who are interested incurrent and emerging implementations of phototherapy. It can serve as an introductory reference and a textbook for advanced undergraduate and graduate courses in medical physics and biomedical engineering. The emphasis is on thescience underlying the various phototherapy pro cedures, which encompasses aspects of classical and molecular photophysics, biological photochemistry, photobiology and biophotonics. Topics that do not usually appear in other generalsources include the theory and applications of tissue optics, Monte Car lo simulation, light dosimetry, and analytical modeling of laser surgery. Many illustrative problems with answers are provided to exemplify the more quantitativeaspects of each topic
Note:Springer eBooks
Contents:An Overview of Phototherapy
Optical Physics and Biotechnology
Phototherapy Light Sources
Quantum Description of Light Interactions with Matter
Tissue Optics
Photochemical Damage to Biological System
Optical Methods of Imaging and Diagnosis
Light Dosimetry Modeling for Phototherapy
Laser Interactions with Tissues
Photodynamic Therapy: Science and Technology
Photodynamic Therapy: Clinical Aspects
Phototherapy of Skin Disease: Science and Technology
Phototherapy of Neonatal Jaundice
ISBN:9781402028854
Series:e-books
Series:SpringerLink (Online service)
Series:Physics and Astronomy (Springer-11651)
Keywords: Oncology , Dermatology , Physical optics , Biomedical engineering
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2005-9780387228273:ONLINE Show nearby items on shelf
Title:Tutorials on Emerging Methodologies and Applications in Operations Research [electronic resource] : Presented at Informs 2004, Denver, CO
Author(s): H J G
Date:2005
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Operations Research emerged as a quantitative approach to problem-solving in World War II. Its founders, who were physicists, mathematicians, and engineers, quickly found peace-time uses for this new field. Moreover, we can saythat Operations Researc h (OR) was born in the same incubator as computer science, and through the years, it has spawned many new disciplines, including systems engineering, health care management, and transportation science.Fundamentally, Operations Research crosses discipline domains to seek solutions on a range of problems and benefits diverse disciplines from finance to bioengineering. Many disciplines routinely use OR methods. Many scientificresearchers, engineers, and others will find the methodological presentations in th is book useful and helpful in their problem-solving efforts. ORs strengths are modeling, analysis, and algorithm design. It provides a quantitativefoundation for a broad spectrum of problems, from economics to medicine, from environmental control to sport s, from e-commerce to computational geometry. The primary purpose of TUTORIALS ON EMERGING METHODOLOGIES AND APPLICATIONS INOPERATIONS RESEARCH is to provide a reference for practitioners and academics who seek a clear, concise presentation of developing methodologies, hence providing themselves with the capability to apply these methods to new problems.The field of Operations Research is always changing. Its changes are driven by the technology it uses and that it extends, and the applications that it af fects. Relevant changes in the field have a permanent effect on the conduct of ORand are vital to anyone who wants to be current in the field. Each chapter presents a new developing methodology in Operations Research. Each chapter examines each topic with clarity and depth, and organizes the examination around thefollowing questions: (1) What the developing methodology basically is about? (2) Why is it important? and (3) Where can I learn more?
Note:Springer eBooks
Contents:Heuristic Search for Network Design
Polyhedral Combinatorics
Radiation Oncology and Optimization
Parallel Algorithm Design for Branch and Bound
Computer
Aided Design for Electrical and Computer Engineering
Nonlinear Programming and Engineering Applications
Connecting MRP, MRP II and ERP
Supply Chain Production Planning via Optimization Models
ISBN:9780387228273
Series:e-books
Series:SpringerLink (Online service)
Series:International Series in Operations Research & Management Science, 0884-8289 : v76
Series:Mathematics and Statistics (Springer-11649)
Keywords: Mathematics , Computer science , Computational complexity , Computer aided design , Computer science Mathematics , Operations research
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2003-9784431659587:ONLINE Show nearby items on shelf
Title:Morphogenesis and Pattern Formation in Biological Systems Experiments and Models
Author(s):
Date:2003
Size:1 online resource (32 p.)
Note:10.1007/978-4-431-65958-7
Contents:Models for Morphogenesis and Pattern Formation -- Pattern Forming Reactions and the Generation of Primary Embryonic Axes -- Spatial Pattern Formation and Morphogenesis in Development: Recent Progress for Two Model Systems -- Alan
Turing and “The Chemical Basis of Morphogenesis” -- On the Stochastic Geometry of Growth -- The Moving Grid Finite Element Method Applied to Biological Problems -- Morphogenesis and Pattern Formation in Animals -- Regulation of Pattern
Formation by the Interaction between Growth Factors and Proteoglycans -- Changing Roles of Homeotic Gene Functions in Arthropod Limb Development -- Variation, Adaptation and Developmental Constraints in the Mimetic Butterfly Papilio
dardanus -- Formation of New Organizing Regions by Cooperation of hedgehog, wingless, and dpp in Regeneration of the Insect Leg a Verification of the Boundary Model -- The Heterotopic Shift in Developmental Patterns and Evolution of
the Jaw in Vertebrates -- Morphogenesis and Pattern Formation in Plants -- The Development of Cell Pattern in the Arabidopsis Root Epidermis -- Pattern Formation during Dicotyledonous Plant Embryogenesis -- Regulation of Inflorescence
Architecture and Organ Shape by the ERECTA Gene in Arabidopsis -- Axis-dependent Regulation of Lateral Organ Development in Plants -- Formation of a Symmetric Flat Leaf Lamina in Arabidopsis -- Morphogenesis and Pattern Formation
Viewed from the Behaviour of Individual Cells -- Pattern Formation by Cell Movement in Closely-Packed Tissues -- Positioning of Cells at their Intrinsic Sites in Multicellular Organisms -- Spatial Pattern and Structure Formation in
Ecological Systems -- Biological Invasion into Periodically Fragmented Environments: A Diffusion-Reaction Model -- Spatial Pattern Formation in Plant Communities -- The Mode of Competition and Spatial Pattern Formation in Plant
Communities -- Formation of a Structure of Exponentially Forking Branches with a Steady-state Amount of Current-year Shoots in a Hardwood Tree Crown -- Spatio-Temporal Pattern Formation in Epidemiology -- Patterns in Epidemiology of
Sexually Transmitted Diseases in Human Populations -- Backward Bifurcation in a Model for Vector Transmitted Disease -- Morphogenesis and Pattern Formation in Medicine -- Mathematical Modelling of Solid Tumour Growth: Applications of
Pre-pattern Formation -- The Formation of Branching Systems in Human Organs -- Computer Simulation on Morphogenesis of Colonic Neoplasia -- The Effects of Cell Adhesion on Solid Tumour Geometry -- Diversity of Biological Patterns in
the Fossil Record and Their Meaning in Morphological Evolution -- Pattern Formation and Function in Palaeobiology -- Why do Univalve Shells of Gastropods Coil so Tightly? A Head-Foot Guidance Model of Shell Growth and its Implication
on Developmental Constraints -- Computer Modeling of Microscopic Features of Molluscan Shells -- How Anomalocaris Swam in the Cambrian Sea A Theoretical Study Based on Hydrodynamics -- Morphology and Function of Cuticular Terraces in
Stomatopoda (Crustacea) and Mantodea (Insecta)
ISBN:9784431659587
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Mathematics , Infectious diseases , Oncology , Biodiversity , Evolutionary biology , Biomathematics , Mathematics , Mathematical and Computational Biology , Infectious Diseases , Oncology , Biodiversity , Evolutionary Biology
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2002-9780387216058:ONLINE Show nearby items on shelf
Title:Cancer Precursors Epidemiology, Detection, and Prevention
Author(s):
Date:2002
Size:1 online resource (430 p.)
Note:10.1007/b97323
Contents:Site-Specific Precancerous Conditions -- Biological Basis of Carcinogenesis -- Mechanisms and Biological Markers of Carcinogenesis -- Morphology of Cancer Precursor Lesions -- Issues Related to Measurement and Interpretation of Cancer
Precursors -- Collection, Processing, and Analysis of Preneoplastic Specimens -- Intermediate Markers in Cancer Research: Theoretical and Practical Issues in the Use of Surrogate Endpoints -- Assessing Epidemiological Relations and the
Role of Measurement Errors -- Site-Specific Precancerous Conditions -- Upper Aerodigestive Tract -- Esophagus -- Stomach -- Colon and Rectum -- Anus -- Liver -- Pancreas -- Lung -- Skin -- Breast -- Cervix -- Endometrium -- Ovary --
Vulva and Vagina -- Prostate -- Bladder -- Control of Cancer Precursors -- Screening -- Chemoprevention -- Evidence-Based Policy Recommendations on Screening and Prevention -- Conclusion -- Prospects
ISBN:9780387216058
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Medicine , Cancer research , Health promotion , Oncology , Epidemiology , Medicine & Public Health , Oncology , Epidemiology , Health Promotion and Disease Prevention , Cancer Research
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-2001-9781475734669:ONLINE Show nearby items on shelf
Title:Applied Statistics in the Pharmaceutical Industry With Case Studies Using S-Plus
Author(s):
Date:2001
Size:1 online resource (514 p.)
Note:10.1007/978-1-4757-3466-9
Contents:1: Introduction -- 1. Statistics and the Drug Development Process -- 2: Basic Research and Preclinical Studies -- 2. One-Factor Comparative Studies -- 3: Pre-Clinical Safety Assessment -- 3. Analysis of Animal Carcinogenicity Data --
4. Analysis of Toxicokinetic and Pharmacokinetic Data from Animal Studies -- 4: Phase I Studies -- 5. Analysis of Pharmacokinetic Data -- 6. Graphical Presentation of Single Patient Results -- 7. Graphical Insight and Data Analysis for
the 2,2,2 Crossover Design -- 8. Design and Analysis of Phase I Trials in Clinical Oncology -- 9. Patient Compliance and its Impact on Steady State Pharmacokinetics -- 10. Analysis of Analgesic Trials -- 5: Phase II and Phase III
Clinical Trials -- 11. Power and Sample Size Calculations -- 12. Comparing Two Treatments in a Large Phase III Clinical Trial -- 13. Analysis of Variance: A Comparison Between SAS and S-PLUS -- 14. Permutation Tests for Phase III
Clinical Trials -- 15. Sample Size Reestimation -- 16. Meta-Analysis of Clinical Trials -- 6: Phase IV Studies -- 17. Analysis of Health Economic Data -- 7: Manufacturing and Production -- 18. Evaluation of the Decimal Reduction Time
of a Sterilization Process in Pharmaceutical Production -- 19. Acceptance Sampling Plans by Attributes
ISBN:9781475734669
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Statistics , Bioinformatics , Computational biology , Statistics , Statistics for Life Sciences, Medicine, Health Sciences , Computer Appl. in Life Sciences
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-1988-9783642456510:ONLINE Show nearby items on shelf
Title:Cell Kinetic Modelling and the Chemotherapy of Cancer
Author(s): Helmut Knolle
Date:1988
Size:1 online resource (157 p.)
Note:10.1007/978-3-642-45651-0
Contents:I. Mathematical models of cell populations -- 1. Proliferation and differentiation of cells -- 2. The cell cycle -- 3. The simple model of tumor growth -- 4. The extended model of tumor growth -- 5. Cell age distribution and phase
indices -- 6. The general model with distributed cycle time -- 7. The Kendall-Takahashi model -- II. Determination of cell kinetic parameters -- Introduction: Cell kinetic experiments -- III. Cell kinetics and cancer therapy -- 1. The
surviving fraction after a single dose -- 2. Phase-specific cell kill -- 3. Block of the cell cycle -- 4. Recruitment of resting cells -- 5. A complex mathematical model and computer programs -- 6. Implications for drug testing -- 7.
Potential implications for therapy -- 1. Limit theorems for matrix models -- 2. A model with periodic parameters -- 3. Pharmacokinetics and the dose-effect relation -- List of symbols -- References
ISBN:9783642456510
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:Lecture Notes in Biomathematics: 75
Keywords: Medicine , Oncology , Cell biology , Biomathematics , Statistics , Medicine & Public Health , Oncology , Mathematical and Computational Biology , Cell Biology , Statistics for Life Sciences, Medicine, Health Sciences
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-1986-9781461321293:ONLINE Show nearby items on shelf
Title:Biophysics and Cancer
Author(s): Claudio Nicolini
Date:1986
Size:1 online resource (480 p.)
Note:10.1007/978-1-4613-2129-3
Contents:1. Normal Cells and Cancer Cells: Macromolecular Structures and Cellular Functions -- 1.1. Background -- 1.2. Native Chromatin-DNA Structure -- 1.3. Nuclear Structure -- 1.4. What Is a Gene? -- 1.5. Ribosomes -- 1.6. Modification in
the Control of Cell Proliferation -- 1.7. Modifications in the Control of Cell Differentiation -- 1.8. Modifications in the Control of Cell Transformation -- 1.9. Modifications in the Control of Cellular Aging -- 1.10. Membranes --
1.11. Cytoskeleton -- 1.12. Control Mechanisms for Normal versus Abnormal Cell Growth -- 1.13. Molecular Mechanisms and Models for Gene Expression -- 1.14. Conclusions and Future Trends -- 2. Cancer Cause and Prevention -- 2.1.
Background -- 2.2. Possible Causes of Cancer -- 2.3. Cancer Prevention -- 3. Cancer Detection and Treatment -- 3.1. Background -- 3.2. Present Status of Human Cancer Detection and Treatment -- 3.3. Alternative Analytical Approaches --
3.4. New Observables -- 3.5. Theoretical Simulation at the Cellular Level: Optimized Drug Metabolism Parameters in Animals -- 3.6. Treatment Optimization in Animals -- 3.7. Drug Interaction and Molecular Perturbation in Animals -- 3.8.
Extrapolation to Human Cancer -- 4. Experimental Probes -- 4.1. Background -- 4.2. Preparative Tools -- 4.3. Probes for Lower-Order Structures -- 4.4. Probes for Higher-Order Structures in Situ -- 5. Theoretical Probes -- 5.1.
Background -- 5.2. Enzyme Kinetics -- 5.3. Signal Processing and Analysis -- 5.4. Statistical Mechanics and Thermodynamics of Cell Structures -- 5.5. Polyelectrolyte Theory of Interactions among Biopolymers -- 5.6. Physicochemical
Model for Dye-Nucleic Acid Interaction in Situ -- 5.7. Electromagnetic Theory of Polarized Light Scattering by Large Biopolymers -- 5.8. Random Walk Model of Biopolymers -- 5.9. Mean Field Theory of Gel Biopolymers -- Epilogue: A Final
Comment -- Problems -- References
ISBN:9781461321293
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Physics , Oncology , Animal physiology , Biophysics , Biological physics , Physics , Biophysics and Biological Physics , Oncology , Animal Physiology
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-1984-9781461327899:ONLINE Show nearby items on shelf
Title:Nonlinear Electrodynamics in Biological Systems
Author(s):
Date:1984
Size:1 online resource (604 p.)
Note:10.1007/978-1-4613-2789-9
Contents:Nonlinear Effects of Electromagnetic Fields on Whole Organisms, Living Tissues and Tissue Preparations -- Nonlinear, Nonequilibrium Aspects of Electromagnetic Field Interactions at Cell Membranes -- Use of Bone Cell Hormone Response
Systems to Investigate Bioelectromagnetic Effects on Membranes In Vitro -- Strong Interactions of Radiofrequency Fields With Nucleic Acid -- Nonthermal Resonant Action of Millimeter Microwaves on Yeast Growth -- Effects on Nervous
Tissue of Exposure to Electromagnetic Fields -- Neurotransmitter Release Stimulated in a Clonal Nerve Cell Line by Low Intensity Pulsed Magnetic Fields -- Natural AC Electric Fields In and About Cells -- Nonlinear Dynamics of Organic
Molecules, Including Biomolecules -- The Energetics and Molecular Dynamics of the Proton Pumping Photocycle in Bacteriorhodopsin -- Presence of Nonlinear Excitations in DNA Structure and Their Relationship to DNA Premelting and to Drug
Intercalation -- Solitons and Bioenergetics -- Nonlinear Dynamics of Globular Proteins -- Solitons in Synthetic and Biological Polymers -- Picosecond Relaxations in Proteins and Biopolymers Observed by MM-Wave Spectroscopy -- Nonlinear
Mechanisms in Molecular Energy Transfer -- Nonlinear Excitations in Polyacetylene -- Prospects for a Bioelectronic Technology -- Communication With Submicron Structures: Perspectives in the Application of Biomolecules to Computer
Technology -- Langmuir-Blodgett Films in Microelectronics -- Nonlinear Tunneling Barriers at High Frequencies and Their Possible Logic Processing Function in Biological Membrane -- Molecular Electronics: An Opportunity for a
Biotechnical Synergism -- Nonlinear Electrodynamics in Cellular Electrochemistry -- Radiofrequency Radiation and Chemical Reaction Dynamics -- On the Growth of Cellular Tissues Under Constant and Environmental Conditions -- Ionic
Currents and Field Effects in Neural Extracellular Spaces -- Frequency Selective Propagation of Extracellular Electrical Stimuli to Intracellular Compartments -- Electromagnetic Surface Wave Penetration of Biological Media -- Models of
Nonlinear Processes -- Conceptual Models of Cooperative Processes in Nonlinear Electrodynamics -- Entrainment-Quasiperiodicity-Chaos-Collaps: Bifurcation Routes of Externally Driven Self-Sustained Oscillating Systems -- Field Induced
Resonance and Chaos in Nonlinear Conservative Systems -- Solitary Waves As Fixed Points of Infinite Dimensional Maps -- Nonlinear Phenomena in a Dispersive System With Application to Water Waves -- Boson Condensation in Biological
Systems -- Order and Structures in Living Systems -- Applications of Nonlinear Physics in Biophysics, Biochemistry and Cell Biology -- General Theory of Coherent Excitations in Biological Systems -- Millimeter-Wave and Far-Infrared
Spectroscopic Properties of Cellular Systems -- Spectroscopic Studies of Nerves -- The Modification of Davydov Solitons by the Extrinsic H-N-C=O Group -- Nonlinear Phenomena in Bioenergetics and Oncology as Seen in 25 Years of Research
With Millimeter Microwaves and Raman Spectroscopy -- Nonlinear Electrodynamics in Cytoskeletal Protein Lattices -- Bridging the Gap
ISBN:9781461327899
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Physics , Biophysics , Biological physics , Physics , Biophysics and Biological Physics
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-1981-9783642464416:ONLINE Show nearby items on shelf
Title:Optimization of Human Cancer Radiotherapy
Author(s): George W Swan
Date:1981
Size:1 online resource (284 p.)
Note:10.1007/978-3-642-46441-6
Contents:1 General Introduction -- 1.1 Introduction -- 1.2 History of Cancer and its Treatment by Radiotherapy -- 1.3 Some Mathematical Models of Tumor Growth -- 1.4 Spatial Distribution of the Radiation Dose -- 2 Survival Curves from
Statistical Models -- 2.1 Introduction -- 2.2 The Target Model -- 2.3 Single-hit-to-kill Model -- 2.4 Multitarget, Single-hit Survival -- 2.5 Multitarget, Multihit Survival -- 2.6 Single-target, Multihit Survival -- 2.7 Properties of
In Vitro Survival Curves -- 3 A Molecular Model of cell Survival -- 3.1 Introduction -- 3.2 The Molecular Model -- 3.3 Interpretations of the Molecular Model -- 4 Kinetic Models of Biological Radiation Response -- 4.1 Introduction --
4.2 Basic Postulates in the Dienes Model -- 4.3 Low LET Kinetic Models with no Recovery -- 4.4 Further Discussion of the Models -- 4.5 Low LET Kinetic Models with Recovery -- 4.6 Low LET and High LET Kinetic Model with No Recovery --
4.7 Other Kinetic Schemes: Sparsely-ionizing Radiation -- 4.8 Kinetic Schemes with Age-specific Compartments in the Cell Cycle -- 4.9 Thermal Potentiation of Cell Killing -- 5 Cell Survival after Successive Radiation Fractions -- 5.1
Introduction -- 5.2 Some Results in Connection with Instantaneous Cell Kill and Exponential Tumor Growth -- 5.3 Instantaneous Cell Kill Followed by Logistic Growth of Normal Tissue -- 5.4 Cohen’s Cell Population Kinetics Programs --
5.5 A Model of Radiation Therapy with Resistant and Sensitive Cell Populations -- 5.6 Dose Fractionation and General Survival Curves -- 6 Optimization Models in Solid Tumor Radiotherapy -- 6.1 Introduction -- 6.2 Optimal Radiotherapy
of Tumor Cells Based on Cumulative Radiation Effect and a Multitarget, Single-hit Survival Function -- 6.3 Optimal Radiotherapy of Tumor Cells Based on Cumulative Radiation Effect and an Exponential-quadratic Survival Expression -- 6.4
Fractionation Scheme with a Four Level Population Tumor Model -- 6.5 A Dynamic Programming Solution to the Problem of the Determination of Optimal Treatment Schedules -- 6.6 Optimal Treatment Schedules in Fractionated Radiation Therapy
for Fischer’s Tumor Model -- 6.7 Optimal Radiation Schedules with Cell Cycle Analysis -- 7 Numerical Solution of Multistage Optimal Control Problems -- 7.1 Introduction -- 7.2 Continuous Time Optimal Control -- 7.3 Optimization of
Multistage Systems -- 7.4 Multi-dimensional Optimization by Gradient Methods -- 7.5 Gradient Method with Penalty Function -- 7.6 A Numerical Scheme for a Nonlinear Problem -- 7.7 The Method of Conjugate Gradients -- 7.8 Discrete
Dynamic Programming -- 8 Some Optimization Criteria in Radiotherapy -- 8.1 Introduction -- 8.2 Therapeutic Policy, Strategy and Tactics -- 8.3 Optimization and Clinical Trials -- 8.4 Score Functions and Age Response Functions -- 8.5
Comparison of Models Used in Optimization Procedures -- 8.6 The Complication Probability Factor -- 9 The Optimization of External Beam Radiation Therapy -- 9.1 Introduction -- 9.2 Some Approaches for Treatment Plans -- 9.3 Linear
Programming -- 9.4 Linear Programming and Radiation Treatment Planning -- 9.5 Optimization of External Beam Radiation Therapy Using Nonlinear Programming -- 9.6 Quantitative Study of Relative Radiation Effects and Isoeffect Patterns --
10 Reconstructive Tomography -- 10.1 Introduction -- 10.2 Reconstruction Algorithm -- 10.3 Numerical Approximations for the Attenuation Coefficient -- 10.4 Cross-sectional Absorption Density Reconstruction for Treatment Planning --
10.5 Towards the Optimization of Dose Reduction in Computerized Tomography -- 10.6 Other Imaging Technologies -- Appendix 1 -- Appendix 2 -- Appendix 3
ISBN:9783642464416
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:Lecture Notes in Biomathematics: 42
Keywords: Medicine , Cancer research , Oncology , Biomathematics , Medicine & Public Health , Oncology , Mathematical and Computational Biology , Cancer Research
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover
Image
Call number:SPRINGER-1980-9781461330301:ONLINE Show nearby items on shelf
Title:Bladder Tumors and other Topics in Urological Oncology
Author(s):
Date:1980
Size:1 online resource (528 p.)
Note:10.1007/978-1-4613-3030-1
Contents:TNM Classification of Urological Tumors — 1978 Edition -- T Category in Renal Carcinoma -- TNM Classification in Urinary Bladder Tumors: Value of Ta Category for Noninfiltrating Exophytic Tumors -- Prednimustine -- Orgotein Efficacy
in Ameliorating Side Effects Due to Radiation Therapy -- Metronidazole: A Radiosensitizer of the Hypoxic Cells -- Cis-Diammine-Dichloro-Platinum Single Drug and Combination Chemotherapy in the Treatment of Genitourinary Cancer -- The
Aims and Activities of the EORTC Urological Group -- WHO Collaborating Center for Research and Treatment of Urinary Bladder and Prostatic Carcinoma -- Chemical Carcinogenesis — A Review and Personal Observations with Special Reference
to the Role of Tobacco and Phenacetin in the Production of Urothelial Tumors -- Pathology of Bladder Tumors. The Urologist’s Point of View -- Newer Aspects of Research in the Field of Bladder Tumors -- Cytology of Bladder Tumors —
Round Table -- Scanning and Transmission Electron Microscopy of Hyperplastic and Neoplastic Human Urothelium -- In Situ Carcinoma of the Bladder -- Primary and Secondary Carcinoma-In-Situ -- Computed Tomography of Bladder Tumors --
Transrectal Ultrasonography: Staging of Bladder Tumors -- Lymphangiography in Advanced Bladder Cancer -- Clinical Significance of Urinary CEA Estimations in the Follow-Up of Patients with Bladder Carcinoma -- Glycosaminoglycans (GAG)
in the Normal and Neoplastic Urinary Bladder — Preliminary Results -- Collagenase Activity in Human Bladder Cancers -- The Copenhagen Bladder Cancer Project 1968–1971 -- Factors Influencing Prognosis in Patients with Bladder Tumors --
Urinary Tract Infection in Patients with Bladder Tumor -- Adenocarcinoma of the Bladder -- to Immunology and Immunotherapy of Bladder Tumors -- Immune Response in Bladder Cancer -- Monocyte Function in Bladder Cancer -- T and B
Lymphocytes in Patients with Bladder Tumors -- ABH-Antigenicity in T1 Urothelial Tumors -- Humoral and Cellular Immune Response in Patients with Transitional Cell Carcinoma of the Urinary Bladder (TCC) Against Bladder Carcinoma Cells
in Tissue Culture -- Immunotherapy in Bladder Cancer -- Intravesical BCG (Bacillus Calmette-Guerin) in the Management of T1 Nx Mx Transitional Cell Tumors of the Bladder: A Toxicity Study -- BCG Vaccine in the Treatment of
Noninfiltrating Papillary Tumors of the Bladder -- Transurethral Surgery -- Transurethral Resection or Cystectomy? An Attempt to Answer this Question by an Evaluation of 688 Patients with Carcinoma of the Bladder (with Special
Reference to Age, Sex, Stage, and the Presence of Associated Disease) -- Partial Cystectomy -- Autologous Human Skin Flaps in Partial Replacement of the Bladder Wall -- Indications for Cystectomy -- The Results of Total Cystectomy for
Carcinoma of the Bladder -- Radical Cystectomy in Advanced Bladder Tumors -- Cancer of the Urethra Following Cystectomy -- Supravesical Urinary Diversion -- Treatment of the Cancer of the Bladder by Irradiation, Cystoprostatectomy and
Ileocystoplasty -- A Type of Rectal Pouch for Urinary Diversion After Cystectomy -- Comparison of Bricker and Wallace Methods of Ureteroileal Anastomosis in Urinary Diversion -- Lymphadenectomy in Bladder Cancer -- Effects of
Intravesical Formaldehyde-Instillation (Experimental and Clinical Results) -- Hydrostatic Pressure Technique and Intravesical Instillation of Formalin: Methods for the Control of Severe Bleeding from the Bladder -- Intravesical
Hyperthermia for Transitional Cell Carcinoma of the Bladder -- Hyperthermia and Bladder Cancer -- Radiotherapy in the Management of Bladder Carcinoma -- Carcinoma of the Bladder Category T3 Nx, 0–4 MO Treated by Preoperative
Irradiation Followed by Cystectomy at the Rotterdam Radiotherapy Institute -- Surgical Treatment of 8l Deep Infiltrating Bladder Tumors after Preoperative Irradiation -- Cystectomy Following Full Course Irradiation -- Complications of
Irradiation of Urological Tumors -- Post-Diversion, Pre-Cystectomy Irradiation for Transitional Cell Carcinoma of the Bladder -- Treatment of Malignant Tumors of the Bladder by Iridium 192 Wiring -- Carcinoma of the Urinary Bladder
Treated by Interstitial Radium Implant -- Radioactive Source Implantation in Bladder Tumors -- Intravesical Treatment of Superficial Urinary Bladder Tumors with Adriamycin -- Intravesical Therapy with Adriamycin in Patients with
Superficial Bladder Tumors -- Local Treatment of Uroepithelial Bladder Tumors with Adriamycin -- Adriamycin Therapy in Carcinoma in Situ: A Preliminary Report -- Bladder Instillation of Adriamycin in Multiple Recurrent Non-Invasive
Papillomatous Bladder Tumors -- Survival in Patients Treated with Epodyl (1968–1978) -- Long-Term Intracavitary Epodyl® in Multiple or Extensive Papillary Tumors of the Urinary Bladder -- Treatment of Multiple Non-Invasive Bladder
Tumors with Intravesical Epodyl® -- The Treatment of Single and Multiple Papillary Tumors of the Bladder (Ta/Tl NX MO) -- Adjuvant Therapy of T1 Bladder Carcinoma: Preliminary Results of an EORTC Randomized Study -- Intravesical
Cis-Platinum in Bladder Tumors: Toxicity Study -- The Treatment of Bladder Cancer with Vitamin A -- The Veterans Administration Study of Chemo-Prophylaxis for Recurrent Stage I Bladder Tumors: Comparisons of Placebo, Pyridoxine, and
Topical Thiotepa -- Flat Carcinoma In-Situ of the Bladder Treated by Systemic Cyclophosphamide — A Preliminary Report -- Methotrexate Therapy for Multiple Tl Category Bladder Carcinoma -- The Place of Chemotherapy in the Treatment of
Patients with Invasive Carcinoma of the Bladder -- Chemotherapy in the Treatment of Invasive Bladder Cancer -- 5-Fluorouracil and Adriamycin in Locally Recurrent and/or Metastatic Bladder Cancer -- Adjuvant Chemotherapy Following
Primary Irradiation in T3 Bladder Cancer -- 5-Fluorouracil in the Treatment of Recurrent Cancer of the Urinary Bladder -- Radiotherapy, Chemotherapy and Immunotherapy for Carcinoma of the Bladder -- Integrated Therapy for Invasive
Bladder Carcinoma -- Cancer Chemotherapy, with Special Emphasis on the Role and Influence of Clinical Trials -- Oestrogen — Androgen Balance in Human Breast and Prostate Cancer -- Steroid Receptors in Human Prostatic Tissue -- Hormonal
Receptors in Human Prostate: A Computerized Study of Normal and Pathological Tissue Samples -- Androgen Receptors in Prostatic Cancer -- Transrectal Aspiration Biopsy of the Prostate with Franzen’s Instrument -- Treatment of Prostatic
Cancer with Medroxyprogesterone-Acetate (MPA) -- External Irradiation of Prostatic Cancer and Indicators for Failure of Treatment -- Intraurethral Irradiation of Prostatic Cancer using Afterloading Technique -- Review of the Veterans
Administration Studies of Cancer of the Prostate and New Results Concerning Treatment of Stage I and II Tumors -- Estracyt -- Combined Treatment with Bleomycin in Penile Carcinoma -- Association of Surgery and Chemotherapy in
Metastatic Testicular Cancer -- Speakers
ISBN:9781461330301
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:Ettore Majorana International Science Series, Life Sciences : 1
Keywords: Medicine , Oncology , Medicine & Public Health , Oncology
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Full Text:Click here
Location: ONLINE

Cover Image
Call number:RC271.R3R3317::1994 Show nearby items on shelf
Title:Radiation oncology : technology and biology
Author(s): Peter M. Mauch
Date:1994
Publisher:W.B. Saunders, Philadelphia
Size:594
ISBN:0721667244
Keywords: Cancer Radiotherapy.
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
Location: MAIN

Cover Image
Call number:RC271.R3M5935::1999 Show nearby items on shelf
Title:The modern technology of radiation oncology: A compendium for medical physicists and radiation oncologists
Author(s): Jake Van Dyk (ed.)
Date:1999
Publisher:Madison, Wis. : Medical Physics Pub.
Size:1072 p.
Note:v. 1 of 2 v. set
Contents:Ch. 1. Radiation oncology overview -- Ch. 2. Clinical implementation of technology and the quality assurance process -- Ch. 3. Patient immobilization -- Ch. 4. Sumulators -- Ch. 5. CT Simulators -- Ch. 6. Simulator Computed tomography -- Ch. 7. Imag ing for radiation therapy planning (MRI, nuclear medicine, ultrasound) -- Ch. 8. Computerized radiation treatment planning systems -- Ch. 9. Kilovoltage x-rays -- Ch. 10. Cobalt-60 teletherapy-- Ch. 11. Medical accelerators -- Ch. 12. Beam shaping and int ensity modulation -- Ch. 13. Megavoltage radiography for treatment verification -- Ch. 14. Radiation oncology information management system -- Ch. 15. Tomotherapy -- Ch. 16. Stereotactic irradiation -- Ch. 17. Special techniques in radiotherapy -- Ch. 18. Brachytherapy -- Ch. 19. Dose measuring tools -- Ch. 20. Proton therapy -- Ch. 21. Neutron therapy -- Ch. 22. Hyperthermia -- Ch. 23. Photodynamic therapy -- Ch. 24. Boron neutron capture therapy -- Ch. 25. Monoclonal antibody and the other internal emit ter therapies.
ISBN:0944838383
Keywords: Cancer Radiotherapy. , Medical physics. , Radiology, Medical. , Cancer Radiotherapy Equipment and supplies. , Neoplasms radiotherapy. , Equipment Design. , Radiotherapy instrumentation. , Radiotherapy methods. , Technology, Radiologic.
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
Location: MAIN

Cover
Image
Call number:RC271.R3.M5935:V2 Show nearby items on shelf
Title:The modern technology of radiation oncology, Volume 2 a compendium for medical physicists and radiation oncologists
Author(s): Jake Van Dyk (ed.)
Date:2005
Edition:1st ed.
Publisher:Madison, Wis. : Medical Physics Pub.
Size:466 p
Contents:Advances in Modern Radiation Therapy, Imaging for Radiation Therapy Planning, Monte Carlo Dose Calucations for External Beam Radiation Therapy, Inverse Treatment Planning, Radiobiological Modeling for Treatment Planning, Intensity-Modulated Radiation Therapy, X-ray Imaging for Verification and Localization, Breathing Control in Radiation Therapy, Calibration of Megavoltage Radiation Beams, Prostate Brachytherapy
ISBN:9781930524255
Keywords: Medical physics.
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
More info: Barnes and Noble
Location: MAIN

Cover Image
Call number:QZ269.A512R::1986 Show nearby items on shelf
Title:Radiation oncology physics, 1986
Author(s): American Association of Physicists in Medicine Summer School (1986 : Miami University)
James G. Kereiakes
Date:1987
Publisher:Published for the American Association of Physicists in Medicine by the American Institute of Physics, New York, N.Y
Size:812
ISBN:0883185334
Series:Medical physics monograph, no. 15
Keywords: Cancer Radiotherapy
Availability:Click here to see Library holdings or inquire at Circ Desk (x3401)
Click to reserve this book Be sure to include your ID please.
More info:Amazon.com
Location: MAIN

Return to the Fermilab Library catalog