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SPIRES-BOOKS: FIND KEYWORD PHARMACOLOGY *END*INIT* use /tmp/qspiwww.webspi1/16461.10 QRY 131.225.70.96 . find keyword pharmacology ( in books using www Cover
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Call number:SPRINGER-2016-9783319235585:ONLINE Show nearby items on shelf
Title:Nonclinical Statistics for Pharmaceutical and Biotechnology Industries
Author(s):
Date:2016
Edition:1st ed. 2016
Size:1 online resource (113 p.)
Note:10.1007/978-3-319-23558-5
Contents:Introduction to Nonclinical Statistics for Pharmaceutical and Biotechnology Industries -- Regulatory Nonclinical Statistics -- How to be a good nonclinical statistician -- Statistical Methods for Drug Discovery -- High-throughput Screening Data Anal ysis -- Quantitative-Structure Activity Relationship Modeling and Cheminformatics -- GWAS for Drug Discovery -- Statistical applications in Design and Analysis of In-Vitro Safety Screening Assays -- Nonclinical safety assessment: an introduction for stati sticians -- General Toxicology, Safety Pharmacology, Reproductive Toxicology and Juvenile Toxicology Studies -- Clinical Assays for Biological Macromolecules -- Recent Research Projects by FDA's Pharmacology and Toxicology Statistics Team -- Design and ev aluation of drug combination studies -- Biomarkers -- Overview of Drug Development and Statistical Tools for Manufacturing and Testing -- Assay Validation -- Lifecycle Approach to Bioassay -- Quality by Design: Building Quality into
Products and Processes -- Process Validation -- Acceptance Sampling -- Process Capability and Statistical Process Control -- Statistical Considerations for Stability and the Estimation of Shelf Life.- In Vitro Dissolution Testing: Statistical Approa ches and Issues -- Assessing Content Uniformity -- Chemometrics and Predictive Modelling -- Statistical Methods for Comparability Studies
ISBN:9783319235585
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Statistics , Pharmacology , Medicine , Statistics , Statistics for Life Sciences, Medicine, Health Sciences , Medicine/Public Health, general , Pharmacology/Toxicology
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Call number:SPRINGER-2012-9783642280795:ONLINE Show nearby items on shelf
Title:Plasmonics [electronic resource] : From Basics to Advanced Topics
Author(s): Stefan Enoch
Nicolas Bonod
Date:2012
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:This book deals with all aspects of plasmonics, basics, applications and advanced developments. Plasmonics is an emerging field of research dedicated to the resonant interaction of light with metals. The light/matter interactionis strongly enhanced a t a nanometer scale which sparks a keen interest of a wide scientific community and offers promising applications in pharmacology, solar energy, nanocircuitry or also light sources. The major breakthroughs of thisfield of research originate from the recen t advances in nanotechnology, imaging and numerical modelling. The book is divided into three main parts: extended surface plasmons polaritons propagating on metallic surfaces, surfaceplasmons localized on metallic particles, imaging and nanofabrication t echniques. The reader will find in the book: Principles and recent advances of plasmonics, a complete description of the physics of surface plasmons, a historicalsurvey with emphasize on the emblematic topic of Wood's anomaly, an overview of modern applic ations of molecular plasmonics and an extensive description of imaging and fabrications techniques
Note:Springer eBooks
Contents:Part I: Fundamentals
Fundamentals
Survey of plasmonics history
Introduction to surface plasmon theory
Theory of Woods anomalies
Part II: Applications
Metallic nanoantennas for field enhanced spectroscopy and microscopy
Nanofabrication for plasmonics
Imaging surface plasmons
Plasmons nano
optics: Designing nanotools for biology and medicine
Part III Advanced topics
Controlling light with plasmonic nanostructures
Theoretical analysis of extraordinary transmission
Localized and not
so
localized plasmons
ISBN:9783642280795
Series:e-books
Series:SpringerLink (Online service)
Series:Springer Series in Optical Sciences, 0342-4111 : v167
Series:Physics and Astronomy (Springer-11651)
Keywords: Engineering , Microwaves
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Call number:SPRINGER-2012-9781461433965:ONLINE Show nearby items on shelf
Title:Space Pharmacology [electronic resource]
Author(s): Virginia E Wotring
Date:2012
Publisher:Boston, MA : Springer US
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Space Pharmacology is a review of the current knowledge regarding the use of pharmaceuticals during spaceflights. It is a comprehensive review of the literature, addressing each area of pharmacokinetics and each majorphysiological system in turn. Eve ry section begins with a topic overview, and is followed by a discussion of published data from spaceflight, and from ground experiments meant to model the spaceflight situation. Includes a discussionlooking forward to the new medical challenges we are li kely to face on longer duration exploration missions. This book is a snapshot of our current knowledge that also highlights areas of unknown
Note:Springer eBooks
Contents:Chapter 1: Introduction
Chapter 2: Absorption
Chapter 3: Distribution
Chapter 4: Metabolism and Excretion
Chapter 5: Central Nervous System
Chapter 6: Cardiovascular System
Chapter 7: Gastrointestinal System
Chapter 8: Musculoskeletal System
Chapter 9: Multiple Systems Spaceflight Effects
Chapter 10: Conclusions
Special Challenges of Long Duration Exploration
References
Abbreviations
ISBN:9781461433965
Series:e-books
Series:SpringerLink (Online service)
Series:SpringerBriefs in Space Development, 2191-8171
Series:Physics and Astronomy (Springer-11651)
Keywords: Pharmaceutical technology , Chemistry, inorganic , Astrophysics
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Call number:SPRINGER-2012-9781461433958:ONLINE Show nearby items on shelf
Title:Space Pharmacology [electronic resource]
Author(s): Virginia E. Wotring
Date:2012
Publisher:Springer US
Size:1 online resource
Note:Brief
Note:Springer 2012 Physics and Astronomy eBook collection
Note:Springer e-book platform
ISBN:9781461433958
Series:SpringerBriefs in Space Development
Series:e-books
Keywords: Extraterrestrial Physics, Space Sciences , Pharmaceutical Sciences/Technology , Inorganic Chemistry
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Call number:SPRINGER-2009-9783540853879:ONLINE Show nearby items on shelf
Title:Colloidal Magnetic Fluids [electronic resource] : Basics, Development and Application of Ferrofluids
Author(s): Stefan Odenbach
Date:2009
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Research into the fascinating properties and applications of magnetic fluids - also called ferrofluids - is rapidly growing, making it necessary to provide at regular intervals a coherent and tutorial account of the combinedtheoretical and experiment al advances in the field. This volume is an outgrow of seven years of research by some 30 interdisciplinary groups of scientists: theoretical physicists describing the behaviour of such complex fluids,chemical engineers synthesizing nanosize magnetic part icles, experimentalist measuring the fluid properties and mechanical engineers exploring the many applications such fluids offer, in turn providing application-guided feedback tothe modellers and requests for the preparation of new fluid types to chemists , in particular those providing optimum response to given magnetic field configurations. Moreover, recent developments towards biomedical applications widensthis spectrum to include medicine and pharmacology. Consisting of six large chapters on synthesis and characterization, thermo- and electrodynamics, surface instabilities, structure and rheology, biomedical applications as well asengineering and technical applications, this work is both a unique source of reference for anyone working in the field and a suitable introduction for newcomers to the field
Note:Springer eBooks
Contents:Synthesis and Characterisation
Thermodynamics, Electrodynamics and Ferrofluid
Dynamics
Surface Instabilities of Ferrofluids
Ferrofluid Structure and Rheology
Biomedical Applications of Magnetic Nanoparticles
Technical Applications
ISBN:9783540853879
Series:e-books
Series:SpringerLink (Online service)
Series:Lecture Notes in Physics, 0075-8450 : v763
Series:Physics and Astronomy (Springer-11651)
Keywords: Chemical engineering , Fluids , Soft condensed matter , Magnetism , Hydraulic engineering , Mechanical engineering
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Call number:SPRINGER-2006-9780387319100:ONLINE Show nearby items on shelf
Title:Modeling in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics [electronic resource] : Homogeneous and Heterogeneous Approaches
Author(s): Panos Macheras
Athanassios Iliadis
Date:2006
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this book. It shows how advanced physical and mathematical methods can expand classical models in order to coverheterogeneous drug-biological pr ocesses and therapeutic effects in the body. The book is divided into four parts the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics the second with drugdissolution, release, and absorption the third with empirica l, compartmental, and stochastic pharmacokinetic models, and the fourth mainly with nonclassical aspects of pharmacodynamics. The classical models that have relevance andapplication to these sciences are also considered throughout. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods. Thistimely and useful book will appeal to graduate students and researchers in pharmacology, pharmaceutical scie nces, bioengineering, and physiology
Note:Springer eBooks
ISBN:9780387319100
Series:e-books
Series:SpringerLink (Online service)
Series:Interdisciplinary Applied Mathematics, 0939-6047 : v30
Series:Mathematics and Statistics (Springer-11649)
Keywords: Mathematics , Toxicology , Biochemistry , Biology Mathematics , Biomedical engineering
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Call number:SPRINGER-2005-9780387260150:ONLINE Show nearby items on shelf
Title:Molecular and Cellular Signaling [electronic resource]
Author(s): Martin Beckerman
Date:2005
Publisher:New York, NY : Springer New York
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:A small number of signaling pathways, no more than a dozen or so, form a control layer that is responsible for all signaling in and between cells of the human body. The signaling proteins belonging to the control layer determinewhat kinds of cells ar e made during development and how they function during adult life. Malfunctions in the proteins belonging to the control layer are responsible for a host of human diseases ranging from neurological disorders tocancers. Most drugs target components in the control layer, and difficulties in drug design are intimately related to the architecture of the control layer. Molecular and Cellular Signaling provides an introduction to molecular andcellular signaling in biological systems with an emphasis on the unde rlying physical principles. The text is aimed at upper-level undergraduates, graduate students and individuals in medicine and pharmacology interested in broadeningtheir understanding of how cells regulate and coordinate their core activities and how dise ases arise when these regulatory systems malfunction, as well as those in chemistry, physics and computer science interested in pursuing careersin biological and medical physics, bioinformatics and systems biology. To that end, the book includes backgroun d information and review sections, and chapters on signaling in the immune, endocrine (hormonal) and nervous systems. It haschapters on cancer, apoptosis and gene regulation, and contains chapters on bacteria and viruses. In those chapters not specificall y devoted to pathogens, connections between diseases, drugs and signaling are made. Each chapter alsofeatures a problem set to facilitate further discussion and understanding. About the Author: Martin Beckerman, Ph.D. is Senior Scientist at the Center for Martin Beckerman, PhD, is a senior research scientist at the Department ofEnergy/National Nuclear Security Administrations Y-12 National Security Complex in Oak Ridge, TN. Prior to assuming his curre
Note:Springer eBooks
Contents:1. Introduction
2. The Control Layer
3. Exploring Protein Structure and Function
4. Macromolecular Forces
5. Protein Folding and Binding
6. Stress and Pheromone Responses in Yeast
7. Two
Component Signaling Systems
8. Organization of Signal Complexes by Lipids, Calcium and Cyclic Amp
9. Signaling by Cells of the Immune System
10. Cell Adhesion and Motility
11. Signaling in the Endocrine System
12. Signaling in the Endocrine and Nervous System through GPCRs
13. Cell Fate and Polarity
14.Cancer
15. Apoptosis
16. Gene Regulation in Eukaryotes
17. Ce
ISBN:9780387260150
Series:e-books
Series:SpringerLink (Online service)
Series:Biological and Medical Physics, Biomedical Engineering, 1618-7210
Series:Physics and Astronomy (Springer-11651)
Keywords: Medicine , Biochemistry , Cytology , Biomedical engineering
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Call number:SPRINGER-2004-9783662061084:ONLINE Show nearby items on shelf
Title:Biomedical Devices and Their Applications
Author(s):
Date:2004
Size:1 online resource (201 p.)
Note:10.1007/978-3-662-06108-4
Contents:1 Biomaterials in Drug Delivery -- 2 Drug Delivery Systems for Localized Treatment of Disease -- 3 Application of Protein Electrophoresis Techniques -- 4 Xenoestrogens as Endocrine Disrupters -- 5 Medical Devices
ISBN:9783662061084
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Physics , Pharmacology , Biotechnology , Endocrinology , Orthopedics , Biophysics , Biological physics , Materials science , Physics , Biophysics and Biological Physics , Characterization and Evaluation of Materials , Orthopedics , Biotechnology , Pharmacology/Toxicology , Endocrinology
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Call number:SPRINGER-2004-9783662061046:ONLINE Show nearby items on shelf
Title:Biomaterials and Tissue Engineering
Author(s):
Date:2004
Size:1 online resource (246 p.)
Note:10.1007/978-3-662-06104-6
Contents:1 Bioactive Materials and Processing -- 2 Biocompatibility of Materials -- 3 Biotechnological Applications of Inorganic Glasses -- 4 Biocomposite Materials for Biotechnology -- 5 Tissue Engineering
ISBN:9783662061046
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Physics , Pharmacology , Biotechnology , Inorganic chemistry , Orthopedics , Biophysics , Biological physics , Materials science , Physics , Biophysics and Biological Physics , Characterization and Evaluation of Materials , Inorganic Chemistry , Orthopedics , Biotechnology , Pharmacology/Toxicology
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Call number:SPRINGER-2003-9780387218663:ONLINE Show nearby items on shelf
Title:Design and Analysis of DNA Microarray Investigations
Author(s): Richard M Simon
Date:2003
Size:1 online resource (19 p.)
Note:10.1007/b97583
Contents:DNA Microarray Technology -- Design of DNA Microarray Experiments -- Image Analysis -- Quality Control -- Array Normalization -- Class Comparison -- Class Prediction -- Class Discovery
ISBN:9780387218663
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Medicine , Cancer research , Molecular biology , Pharmacology , Health informatics , Bioinformatics , Statistics , Biomedicine , Cancer Research , Bioinformatics , Statistics for Life Sciences, Medicine, Health Sciences , Molecular Medicine , Pharmacology/Toxicology , Health Informatics
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Call number:SPRINGER-1998-9781489919472:ONLINE Show nearby items on shelf
Title:Handbook of Research Methods in Human Operant Behavior
Author(s):
Date:1998
Size:1 online resource (669 p.)
Note:10.1007/978-1-4899-1947-2
Contents:I: Basic Considerations -- 1: The Experimental Analysis of Human Operant Behavior -- 2: The Human Subject -- 3: Experimental Design and Analysis in the Laboratory Study of Human Operant Behavior -- II: Reinforcement and Punishment --
4: Reinforcement: Schedule Performance -- 5: Choice and Self-Control -- 6: Negative Reinforcement and Punishment -- III: Stimulus Control -- 7: Stimulus-Control Procedures -- 8: Stimulus Equivalence -- 9: Remembering and Forgetting --
10: Psychophysics: Methods and Analyses of Signal Detection -- IV: Verbal and Social Behavior -- 11: Behavioral Processes of Infants and Young Children -- 12: The Verbal Governance of Behavior -- 13: The Taxonomy of Verbal Behavior --
14: Self-Report Methods -- 15: Social Behavior -- V: New Directions -- 16: Establishment of a Laboratory for Continuous Observation of Human Behavior -- 17: Laboratory Methods in Human Behavioral Ecology -- 18: Human Behavioral
Pharmacology: An Overview of Laboratory Methods -- 19: Self-Experimentation -- Appendix: Ethical Guidelines in Research with Humans
ISBN:9781489919472
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Psychology , Clinical psychology , Psychology , Clinical Psychology
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Call number:SPRINGER-1994-9789401110587:ONLINE Show nearby items on shelf
Title:Computational Approaches in Supramolecular Chemistry
Author(s):
Date:1994
Size:1 online resource (531 p.)
Note:10.1007/978-94-011-1058-7
Contents:1 Water structure from computational chemistry -- 2 Ionic hydrogen bond assemblies in clusters: resources and opportunities for modeling -- 3 Non-covalent interactions in organic crystals, and the calibration of empirical force fields
-- 4 Hydrogen-bond descriptors for solute molecules -- 5 Molecular recognition of dinucleotides and amino acids by artificial receptors containing a bicyclic guanidinium subunit -- 6 Intra- and intermolecular hydrogen bonding control
of supramolecular structure -- 7 New supramolecular architecture based on hydrogen bonding. -- 8 Studies toward computer liquid phase simulations of the solvent-dependency of apolar association strength: conformational analysis of a
cyclophane-pyrene complex by pseudo Monte Carlo and Molecular Dynamics methods -- 9 Rational approaches towards protease inhibition: predicting the binding of thrombin inhibitors -- 10 Receptor-ligand interactions in pharmacology and
drug design -- 11 Modeling interactions with benzene: aryl-aryl, cation-?, and chaotrope-? -- 12 The nature of molecular recognition: examples from host/guest chemistry -- 13 Computational aspects in supramolecular chemistry: chiral
discrimination in chromatography -- 14 Determination of conformationally dependent point charges for potential of mean force simulations -- 15 Structural and dynamic features of molecular clips derived from diphenylglycoluril -- 16
Solvation and complexation: from cation complexation to excited-state stabilisation -- 17 Metallocycles and -clefts -- 18 Experimental approaches to interaction energies and structures in supramolecular complexes -- 19 Complexation of
ions and neutral molecules by functionalized calixarenes -- 20 Experimental and computational studies of cation-? interactions in natural and synthetic receptors. Benzene as a pseudoanion -- 21 Architecture of new concave host
molecules -- 22 MD Simulations on synthetic ionophores and their cation complexes: Comparison of aqueous/non-aqueous solvents -- 23 The role of energy calculations in the design, synthesis and study of biologically active Iron(III
carriers -- 24 A simple approach to modelling supramolecular complexes and mechanically-interlocked molecules -- 25 Molecular motions in catenands and catenates studied by 13C NMR relaxation times -- 26 Simulation of self-assembled
monolayers: Microscopic structure of amino alkylthiols -- 27 Langmuir films of amphiphilic alcohols and surfaces of polar crystals as templates for ice nucleation -- 28 Molecular dynamics study of a sequence specific protein-DNA
interaction -- 29 Molecular dynamics simulation of a DNA binding protein free and in complex with DNA -- 30 Supramolecular interactions and atomic dynamics in proteins and peptide crystals. Jumps, lattice waves, and liquide-like
diffusion -- 31 Molecular recognition: an example from ligand binding to proteins -- 32 HIV-1 proteinase inhibitor binding. The effect of active site conformational restraints on calculated free energies of ligand binding -- 33 Free
energy and binding selectivity -- 34 Structure and dynamics of the sidechains of the gramicidin channel in a DMPC bilayer
ISBN:9789401110587
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:NATO ASI Series, Series C: Mathematical and Physical Sciences: 426
Keywords: Chemistry , Chemoinformatics , Physical chemistry , Chemistry, Physical and theoretical , Computer graphics , Chemistry , Computer Applications in Chemistry , Theoretical and Computational Chemistry , Physical Chemistry , Computer Graphics
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Call number:SPRINGER-1990-9781468458503:ONLINE Show nearby items on shelf
Title:Genetic Toxicology of Complex Mixtures
Author(s):
Date:1990
Size:1 online resource (384 p.)
Note:10.1007/978-1-4684-5850-3
Contents:Development and Application of New Methodologies Applicable to Research on Complex Environmental Mixtures -- Complex Mixtures of Genotoxicants in Air -- Identification of Genotoxic Agents in Complex Mixtures of Air Pollutants -- Human
Exposure to Airborne Mutagens Indoors and Outdoors Using Mutagenesis and Chemical Analysis Methods -- Genetic Toxicology of Airborne Particulate Matter Using Cytogenetic Assays and Microbial Mutagenicity Assays -- Indoor and Outdoor
Sources of Airborne Mutagens in Nonurban Areas -- Characterization of Mutagen Sources in Urban Particulate Matter in Gothenburg, Sweden -- Assessment of the Mutagenicity of Volatile Organic Air Pollutants Before and After Atmospheric
Transformation -- Carcinogenicity of Complex Mixtures in Air Using In Vitro and In Vivo Assays -- Contribution of Polycyclic Aromatic Hydrocarbons and Other Polycyclic Aromatic Compounds to the Carcinogenicity of Combustion Sources and
Air Pollution -- Old and New Carcinogens -- Experimental and Epidemiologic Applications to Cancer Risk Assessment of Complex Mixtures -- Mutagenicity, Carcinogenicity, and Human Cancer Risk from Indoor Exposure to Coal and Wood
Combustion in Xuan Wei, China -- The Role of Nitroarenes in the Mutagenicity of Airborne Particles Indoors and Outdoors -- Complex Mixtures of Genotoxicants in Waters -- Characterization of Mutagenic Compounds Formed During
Disinfection of Drinking Water -- Genotoxic and Carcinogenic Properties of Chlorinated Furanones: Important By-products of Water Chlorination -- Assessment and Identification of Genotoxic Compounds in Water -- Methods to Measure
Genotoxins in Wastewater: Evaluation with In Vivo and In Vitro Tests -- Detection of Genotoxicity in Chlorinated or Ozonated Drinking Water Using an Amphibian Micronucleus Test -- Exposure/Effects Assessment -- The Significance of
Mutagenicity as a Criterion in Ecotoxicological Evaluations -- DNA Adducts and Related Biomarkers in Assessing the Risk of Complex Mixtures -- Immunological Methods for the Detection of Polycyclic Aromatic Hydrocarbon-DNA and Protein
Adducts -- 32P-Postlabeling DNA Adduct Assay: Cigarette Smoke-induced DNA Adducts in the Respiratory and Nonrespiratory Rat Tissues -- Postlabeling Analysis of Polycyclic Aromatic Hydrocarbon: DNA Adducts in White Blood Cells of
Foundry Workers -- Protein Adducts as Biomarkers for Chemical Carcinogens -- Evaluation of DNA Binding In Vivo for Low-Dose Extrapolation in Chemical Carcinogenesis -- Cancer Risks Due to Occupational Exposure to Polycyclic Aromatic
Hydrocarbons: A Preliminary Report -- Future Directions in Research on the Genetic Toxicology of Complex Mixtures
ISBN:9781468458503
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:Environmental Science Research : 39
Keywords: Medicine , Human genetics , Pharmacology , Ecotoxicology , Waste management , Biomedicine , Pharmacology/Toxicology , Human Genetics , Waste Management/Waste Technology , Ecotoxicology
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Call number:SPRINGER-1990-9781468457360:ONLINE Show nearby items on shelf
Title:Transduction in Biological Systems
Author(s):
Date:1990
Size:1 online resource (530 p.)
Note:10.1007/978-1-4684-5736-0
Contents:I. Stimulus-Response Coupling -- A. Transduction in Sensory Cells -- 1 Dynamics of the Release of Calcium by Light and Inositol 1,4,5-Trisphosphate in Limulus Ventral Photoreceptors -- 2 Second Messengers in Invertebrate
Phototransduction -- 3 The cGMP-Gated Channels of Rod and Cone Photoreceptors -- 4 Functional Aspects of the cGMP-Activated Channel from Bovine Rod Outer Segments -- 5 A Complex Regulation of the cGMP-Dependent Channels of Retinal Rod
Membranes by the cGMP Phosphodiesterase -- 6 Transduction, Signal Transference, and Encoding in Composite Chemoreceptors: A Comparison between Gustatory and Arterial Chemoreceptors -- B. Excitation-Secretion Coupling -- 7 Role of
Membrane Receptors in Stimulus-Secretion Coupling -- 8 Glucose Dose Response of Pancreatic ?-Cells: Experimental and Theoretical Results -- 9 Electrical and Secretory Response to Cholinergic Stimulation in Mouse and Human Adrenal
Medullary Chromaffin Cells -- 10 Calcium Currents and Hormone Secretion in the Rat Pituitary Gonadotroph -- 11 Synexin-Driven Membrane Fusion: Molecular Basis for Exocytosis -- 12 Signal Transduction and Ion Permeability in Adrenal
Glomerulosa Cells -- C. Other Transduction Mechanisms -- 13 The Target of Inositol 1,4,5-Trisphosphate in Nonmuscle Cells: Calciosome or Endoplasmic Reticulum? -- 14 Stimulus-Response Coupling in Mammalian Ciliated Cells: The Role of
Ca2+ in Prostaglandin Stimulation -- 15 Hepatocyte Gap Junctions: Metabolic Regulation and Possible Role in Liver Metabolism -- 16 Mechanisms of Frequency Tuning in the Internal Ear -- II. Excitation-Contraction Coupling in Striated
Muscle -- A. Sodium Channels and Sodium Pump -- 17 Coexistence of Different Types of Sodium Channels in Striated Muscle and Nerve -- 18 Sodium Pump in T-Tubules of Frog Muscle Fibers -- B. Calcium Channels in T-Tubule -- 19
Excitation-Contraction Coupling in Barnacle Muscle Fibers: Does Calcium Entry Trigger Contraction Directly? -- 20 Biochemical Structure of the Dihydropyridine Receptor -- 21 Role of Slow Inward Calcium Current in Excitation-Contraction
Coupling -- C. Molecular Architecture of the Triad -- 22 Molecular Architecture of T-SR Junctions: Evidence for a Junctional Complex That Directly Connects the Two Membrane Systems -- 23 Proteins of the Triad Junction of Skeletal
Muscle -- 24 Monoclonal Antibodies as Probes of Triad Structure and Excitation-Contraction Coupling in Skeletal Muscle -- D. Transduction at the Triad -- 25 A Third Role for Calcium in Excitation-Contraction Coupling -- 26 A
Pharmacological Approach to the Physiological Mechanism of Excitation-Contraction Coupling -- 27 A Chemical Mechanism for Excitation-Contraction Coupling in Skeletal Muscle -- 28 What We Know and What We Would Like to Know about the
Role of Inositol 1,4,5-Trisphosphate in Skeletal Muscle -- 29 Calcium Release in Skinned Muscle Fibers: Effect of Inositol 1,4,5-Trisphosphate -- 30 Metabolism of Phosphoinositides in Skeletal Muscle Membranes -- E. Calcium Release --
31 Pharmacology of the Ryania Alkaloids: The Ester A, a Ryanodine Analog That Only Increases Sarcoplasmic Reticulum Calcium Permeability -- 32 Ca2+ Release Channel of Sarcoplasmic Reticulum: Characterization of the Regulatory Sites --
33 Calcium Channels in Sarcoplasmic Reticulum Membranes Isolated from Skeletal Muscle
ISBN:9781468457360
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Life sciences , Physical chemistry , Biochemistry , Plant science , Botany , Animal anatomy , Animal physiology , Biophysics , Biological physics , Life Sciences , Biochemistry, general , Animal Anatomy / Morphology / Histology , Plant Sciences , Animal Physiology , Biophysics and Biological Physics , Physical Chemistry
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Call number:SPRINGER-1986-9781468450651:ONLINE Show nearby items on shelf
Title:A Primer of Human Behavioral Pharmacology
Author(s): Alan Poling
Date:1986
Size:1 online resource (246 p.)
Note:10.1007/978-1-4684-5065-1
Contents:1 Historical Origins of Behavioral Pharmacology -- What Is Behavioral Pharmacology? -- Drugs and Psychiatry -- Drug Abuse, LSD, and Behavioral Pharmacology -- Behavioral Toxicology -- Pharmacology and Behavioral Pharmacology --
Milestones in Behavioral Pharmacology -- Concluding Comments -- 2 Basic Principles of Pharmacology -- Labeling and Classification of Drugs -- Physical Properties of Drugs -- The Fate of a Drug -- Absorption and Route of Administration
-- Distribution of Drugs -- Biotransformation and Elimination -- Drug Kinetics and Dose-Dependent Drug Effects -- Time Course of Drug Action -- Tolerance and Physical Dependence -- Drugs, Receptors, and Neuronal Activity -- Drug
Interactions -- Individual Differences -- Concluding Comments -- 3 Overview of Behavioral Psychology -- Science and Behavioral Psychology -- Respondent Conditioning -- Operant Conditioning -- Nonhuman Research, Human Research, and
Meaningful Inference -- Concluding Comments -- 4 Stimulus Properties of Drugs -- Drugs as Unconditional and Conditional Stimuli -- Distinguishing Discriminative Stimulus Functions of Drugs -- Drugs as Positively Reinforcing Stimuli --
Drugs as Negatively Reinforcing Stimuli -- Patient Noncompliance -- Determinants of Negative Reinforcement -- Concluding Comments -- 5 Drug-Behavior Interactions -- Drug Effects on Learning -- Drug Effects on Stimulus-Controlled
Behavior -- Rate-Dependent Drug Effects -- Consequence-Dependent Drug Effects -- Concluding Comments -- 6 Clinical Drug Assessment -- Psychiatric Diagnosis -- Target Behaviors and Their Assessment -- Experimental Designs and Strategies
-- Concluding Comments -- 7 Drug Abuse -- Drugs as Positive Reinforcers -- Drug Abuse as an Operant Response -- Treating Drug Abuse -- Concluding Comments -- 8 The Future -- References
ISBN:9781468450651
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Psychology , Clinical psychology , Psychology , Clinical Psychology
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Call number:SPRINGER-1984-9781461327912:ONLINE Show nearby items on shelf
Title:Aging and Drug Therapy
Author(s):
Date:1984
Size:1 online resource (523 p.)
Note:10.1007/978-1-4613-2791-2
Contents:Pharmacokinetics in Advancing Age -- Brain Receptors and Aging in Relation to Drug Effect -- Clinical Trials in Old Subjects -- General Symptomatology of Pathogenic Drug Usage in Old Patients -- Epidemiological Consideration of
Adverse Reactions to Drugs -- Drug Compliance -- The Treatment of Sleep Disorders -- Assessment and Management of Confused Old People in General Hospitals -- Treatment of Depression in the Elderly -- Treatment of Chronic Brain Failure
-- Perspective in the Treatment of Dementia -- Physiopathology and Treatment of Transient Ischaemic Attacks -- Psychodynamic Treatment of the Elderly -- Nutrition of Elderly Patients in Long Care Wards -- Disorders of Fluid and
Electrolyte Metabolism in the Elderly -- Long Term Treatment with Oral Antidiabetics -- Insufficiency of Haemoactive Principles in the Elderly and its Treatment -- Plasma Lipids and Frequency of Hyperlipidaemia in the Elderly:
Indications and Cost/Benefit Ratio of Hypolipidaemic Treatment -- Metabolic Bone Disease and Fracture of the Femoral Neck -- The Prophylaxis of Senile Osteoporosis -- Treatment of Post-Menopausal Osteoporosis -- The Role of the
Physician in Femoral Neck Fracture -- Digitalis Metabolism in Aged Patients -- Digitoxin in Elderly Patients with Rapid Atrial Fibrillation -- The Use of the Antiarrythmic Agents in the Elderly -- Diuretic Therapy in Old Patients --
Should Hypertension in the Elderly be Treated? -- Anti-Hypertensive Treatment in the Older Patient -- Treatment of Orthostatic Hypotension -- Treatment of Cardiorespiratory Failure in the Elderly -- Intensive Care of Acute Ischemic
Cardiopathy in Old Patients -- Cardiac Rehabilitation in the Elderly -- Pathophysiology of Urinary Incontinence -- The Pharmacology of Urinary Incontinence -- Perspectives on the Prophylaxis and Therapy of Thromboembolism in the Aged
-- Thrombolytic Therapy in the Elderly -- Antiplatelet Aggregating Agents -- Endogenous Opiates Regulating Pain Perception in the Aged Rat -- Pathophysiology of Prostaglandins, with Particular Reference to the Elderly -- Pain Treatment
in Old Patients
ISBN:9781461327912
Series:eBooks
Series:SpringerLink (Online service)
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Keywords: Physics , Physics , Physics, general
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Call number:SPRINGER-1984-9781461253129:ONLINE Show nearby items on shelf
Title:Neurobiology of the Trace Amines Analytical, Physiological, Pharmacological, Behavioral, and Clinical Aspects
Author(s):
Date:1984
Size:1 online resource (598 p.)
Note:10.1007/978-1-4612-5312-9
Contents:A. Introduction -- Trace Amines: The Early Years -- Trace Amines and the Neurosciences: An Overview -- B. Analysis -- Invited Communications -- Quantification of Trace Amines and Their Metabolites by High Resolution or Metastable
Analysis Using Double Focussing Mass Spectrometry -- The Use of Enzymatic Radioisotopic Microassays for the Quantification of ?-Phenylethylamine, Phenylethanolamine, Tyramine, and Octopamine -- Gas Chromatography for Analysis of the
Trace Amines in Tissues and Body Fluids -- Free Communications -- Studies on Tryptamine Metabolism by GC-MS and HPLC Techniques -- A Rapid and Specific Technique for the Extraction of Tyramine and Octopamine from Biological Tissues for
HPLC Analysis -- Analysis of Octopamine, Dopamine, 5-Hydroxtryptamine, and Tryptophan in the Brain and Nerve Cord of the American Cockroach -- Natural Occurrence and Metabolism of the Isomeric Octopamines and Synephrines -- Octopamine
is Present in Retinas of Various Mammalian Species -- C. Physiology and Pharmacology -- Invited Communications -- Investigation of Trace Amine Metabolism in the Central Nervous System through Measurements on Cerebrospinal Fluid --
Analysis of Trace Amines: Endogenous Levels and the Effects of Various Drugs on Tissue Concentrations in the Rat -- Drug-Induced Changes in the Central Metabolism of Tyramine and Other Trace Monoamines: Their Possible Role in Brain
Functions -- Aminergic Control of the Electrocorticogram: A Progress Report -- Neuronal Transport of Trace Amines: An Overview -- Electrophysiological Studies of the Possible Role of Trace Amines in Synaptic Function -- Effects of
Octopamine and Serotonin on Neurones of Aplysia Californica -- Free Communications -- Individual Housing Stress Elevates Brain and Adrenal Tryptamine Content -- The Uptake and Release of 14C-Tryptamine by Rat Brain Slices --
Tryptamine-Induced Changes in Endogenous 5-Hydroxytryptamine and [3H]-5-HT Release from Mouse Hypothalamic Slices -- Effect of Chronic Haloperidol on the Levels of Blood and Urinary Phenylethylamine and Phenylacetic Acid in Rats -- A
Comparison of effects of Acute and Chronic Administration of Phenelzine and Tranylcypromine on Brain Concentrations of 2-Phenylethylamine, p-Tyramine, and Tryptamine in the Rat -- Phenylethylamine Deamination in the Noradrenergic
Neurotransmitter System -- Effect of Lignocaine on Tyramine and Serotonin Oxidation in Brain -- Degradation Kinetics by MAO of PEA Derivatives. A Model for the Molecular Basis of Their Analgesic and Behavioral effects? -- The Kinetics
of Hydroxylation of Phenylethylamine, Amphetamine, and Phenylalanine in Rodent Tissues -- Chronotropic and Inotropic Selectivity of Substituted Phenylethylamines in the Isolated, Perfused Rabbit Heart -- Trace Amine-Peptide
Interactions on Central Neurones: I. Tryptamine and Substance P -- Trace Amine-Peptide Interactions: II. Phenylethylamine and enkephalin p-Tyramine and enkephalin -- D. Behavior -- Invited Communications -- Beta-Phenylethylamine: Some
Preliminary Chronic Studies -- ?-Phenylethylamine: A Functional Role at the Behavioral Level? -- Differentiation of Phenylethylamine (PE)- and Amphetamine (AMPH)- Induced Behaviors -- Studies on the Mechanism of Action of
?-Phenylethylamine Stereotypy in Rodents: Implications for a ?-Phenylethylamine Animal Model of Schizophrenia -- Free Communications -- Effects of Tryptamine and 5-Hydroxytryptamine on Food Intake in the Rat -- 5-HT Involvement in
Tryptamine-Induced Behavior in Mice -- Hypodipsic Effects of ?-Phenylethylamine, Phenylethanolamine, N-Methylphenylethylamine, and d-Amphetamine: A Temporal Analysis -- Taste-Dependent Effects of Low Doses of ?-Phenylethylamine and
d-Amphetamine on Drinking in the Rat -- ?-Phenylethylamine and d-Amphetamine: Differential Potency in the Conditioned Taste Aversion Paradigm -- Locomotor Stimulant Effect of ?-Phenylethylamine-Naloxone -- E. Clinical Studies --
Invited Communications -- The Origin, Drug Interaction, Urine, Plasma, and CSF Concentrations of Phenylacetic Acid in Normal and Psychiatric Subjects -- The Catabolism of Trace Amines in Some Psychiatric Disorders -- Tyramine and
Depressive Illness -- Phenethylamine, Tyramine, and Other Trace Amines in Patients with Affective Disorders: Associations with Clinical State and Antidepressant Drug Treatment -- Phenylethylamine and Schizophrenia—Clinical and
Pharmacological Results -- Urinary Excretion of Tryptamine in Comparison to Normetanephrine and beta-Phenylethylamine in Human Volunteers after Subchronic Treatment with Different Monoamine Oxidase Inhibitors -- Free Communications --
p-Hydroxyphenylacetic Acid Concentration in the CSF of Patients with Neurological and Psychiatric Disorders -- Noncatecholic Phenylethylamines and MAO Activity in Diabetes and Migraine -- Phenylethylamine and Tardive Dyskinesia --
Phenylethylamine, Phenylacetic Acid, and Methionine Enkephalin Levels in Humans Following Profound Acute Stress -- 14C-Tryptamine Binding in Parkinson’s Disease and Hepatic Coma -- Biochemical and Antidepressant Mechanisms of
L-Deprenyl
ISBN:9781461253129
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Life sciences , Neurosciences , Biochemistry , Life Sciences , Biochemistry, general , Neurosciences
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Call number:SPRINGER-1983-9783642689574:ONLINE Show nearby items on shelf
Title:Radiological Functional Analysis of the Vascular System Contrast Media — Methods — Results
Author(s):
Date:1983
Size:1 online resource (298 p.)
Note:10.1007/978-3-642-68957-4
Contents:Welcoming Address -- I. Physiology -- Physiological Aspects Concerning the Diagnostic Analysis of Circulatory Dynamics -- II. Pharmacology of Contrast Media -- Contrast Media for Cardiovascular Analysis -- The Pharmacological Effect
of Contrast Media on Renal Circulation Measured by Means of Angiodensitometry -- III. Technique of Injection -- Technique for Injection of Contrast Medium -- Model Experiments for Angiocinedensitometry -- IV. Physical and Technical
Basics for the Radiological Analysis of Circulation -- Problems of Choice of Reference System for Quantitative Radiological Circulation Analysis -- Information Content of Cinedensitometric Blood Flow Measurements -- Problems of
Different Methods of Radiographic Absorptiometry of Circulation -- Digital Videodensitometry: Some Approaches to Radiographic Image Restoration and Analysis -- Flow Measurements by Videodensitometry -- Influence of Time Resolution in
Cine and Video Cardangiography -- Automated Digital Image Processing for Hemodynamic Investigations -- Application Fields of Computer Angiography -- Demonstration of Dopamine Effect in Dog Kidneys by Computer Angiography -- V. Clinical
Applications and Results -- Roentgen Cinedensitometry of Blood Circulation -- Arterial Blood Flow -- Coronary Flow Measurements Using Cinedensitometry -- Survey of Techniques for Measuring Myocardial Microperfusion -- Densitometric
Analysis of Cerebral Blood Flow -- Angiocinedensitometry of Renal Blood Circulation by ECG Controlled Injection -- Results of Blood Flow Measurements -- Cinedensitometric Examinations of the Human Abdominal Aorta -- Cinedensitometric
Measurement of Flow in the Femoral and Iliac Arteries During Angioplasty -- Venous Blood Flow -- Determination of Portal and Arterial Liver Hemodynamics by Angiodensitometry -- Videodensitometric Measurement of Venous Return from the
Lower Limb -- Stenoses -- Computer Aided Densitometric Evaluation of Coronary Cineangiograms -- Quantification of Coronary Stenoses -- VI. Angiographic Studies by Image Subtraction -- Systems for Digital Diagnosis of Vessels --
Analysis of the Circulatory System Using Intravenous Contrast Medium Injections -- Importance of Contrast Agent Bolus in Intravenous Subtraction Angiography -- Analytical Function Studies Using Digital Intravenous Angiography as a
Method for Quantitative Analysis of the Circulation -- Functional Possibilities with the Digital Vascular Imaging System -- Digital Subtraction Angiography as a Control Procedure After Surgery and Percutaneous Transluminal Angioplasty
-- VII. Dynamic Studies by Computed Tomography -- Bolus Geometry and Dynamics After Intravenous Injection of Contrast Media -- The Chronogram — Principle and First Results -- Renal Perfusion Studies by Means of CT -- Dynamic Computed
Tomography in Abdominal Tumors: New Aspects for Differential Diagnosis
ISBN:9783642689574
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Keywords: Mathematics , Radiology , Hematology , Functional analysis , Mathematics , Functional Analysis , Imaging / Radiology , Hematology
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Call number:SPRINGER-1979-9781468434835:ONLINE Show nearby items on shelf
Title:Human Evoked Potentials Applications and Problems
Author(s):
Date:1979
Size:1 online resource (498 p.)
Note:10.1007/978-1-4684-3483-5
Contents:Auditory, Somatosensory and Visual Evoked Potentials in the Diagnosis of Neuropathology: Recording Considerations and Normative Data -- Adaptation Effects in the Transient Visual Evoked Potential -- Linguistic Meaning-Related
Differences in ERP Scalp Topography -- Application of Somatosensory Event Related Potentials to Experimental Pain and the Pharmacology of Analgesia -- Hemispheric Differences in Evoked Potentials to Relevant and Irrelevant Visual
Stimuli -- A System Transfer Function for Visual Evoked Potentials -- Somatosensory Evoked Potentials in Man: Maturation, Cognitive Parameters and Clinical Uses in Neurological Disorders -- Event Related Potential Investigations in
Children at High Risk for Schizophrenia -- Late Positive Component (LPC) and CNV During Processing of Linguistic Information -- The Macular and Paramacular Subcomponents of the Pattern Evoked Response -- The Effects of Methylphenidate
Dosage on the Visual Event Related Potential of Hyperactive Children -- Evoked Potential Indicants of Size- and Orientation-Specific Information Processing: Feature-Specific Sensory Channels and Attention -- Maturation and Task
Specificity of Cortical Potentials Associated with visual Scanning -- Multichannel Mapping of Spatial Distributions of Scalp Potential Fields Evoked by Checkerboard Reversal to Different Retinal Areas -- Spontaneous and Evoked Cerebral
Electrical Activity and Localization of Language Function in Children with Minimal Cerebral Dysfunction -- Hemisphere Differences in Event Related Potentials and CNVs Associated with Monaural Stimuli and Lateralized Motor Responses --
Different Variants of Endogenous Negative Brain Potentials in Performance Situations: A Review and Classification -- Event Related Potentials in Language and Non-Language Tasks in Patients with Alexia without Agraphia -- Spatial and
Temporal Distribution of Olfactory Evoked Potentials and Techniques Involved in Their Measurement -- Event Related Scalp Potentials During a Bimanual Choice R. T. Task: Topography and Interhemispheric Relations -- A Trial by Trial
Study of the Visual Omission Response in Reaction Time Situations -- Event Related Potential Research in Psychiatry -- Spatial Distributions of Sensory Evoked Potentials in Psychiatric Disorders -- Contrast Evoked Potentials and
Psychophysics in Multiple Sclerosis Patients -- Event Related Potentials in Development, Aging and Dementia -- Event Related Potential Assessment of Sensory and Cognitive Deficits in the Mentally Retarded -- Anatomical and
Physiological Origins of Auditory Brain Stem Responses (ABR) -- Color Evoked Potentials: Cortical and Subcortical Elements -- Abstracts -- Interactions Between Target and Masking Stimuli: Perceptual and Event Related Potential Effects
-- Cerebral Organization of Event Related Potentials Analyzed by Multidimensional Scaling Techniques -- Electrophysiological Indicators of Cognitive Deficits in Chronic Alcoholics and Geriatric Subjects -- GSR, AEP and CNV in Depressed
Patients and Healthy Controls -- Scalp-Recorded Visual Evoked Subcortical Potentials in Man -- Efficacy of the Scalp-Recorded Visually Evoked Potential in Demonstrating Misrouting of Optic Projections in Man -- Event Related Brain
Potentials in Response to Conscious and Non-Concious Stimuli: Hemispheric Specialization and the Effects of Attention -- Clinical Use of the ABR in an Infant Intensive Care Unit -- The Evoked Potential as a Measure of Brain
Dysfunction: -- Aging, Down’s Syndrome, Alcoholoism, Amytrophic Lateral Sclerosis and Renal Disease -- A New Test of Brain Function: Brain Stem Transmission Time (BTT) -- Equivocation in Prediction Versus No-Prediction Schedules:
Effects on ERSP Measures -- The Utility of ERPs in Determining Age-Related Differences -- Application of ERPs in the Study of Drug Use and Abuse in Man: A Close Look with More Sensitive Tasks and Measurement Techniques -- Auditory
Evoked Potentials and Psychophysical Parameters in Circadian Studies -- Effects of Methylphenidate on Hyperactive Children’s Evoked Responses During Passive and Active Attention -- Evoked Potentials in Senile Dementia --
Electrophysiological and Biochemical Studies in Autistic Children Treated with Vitamin B6 -- Visual Event Related Potentials of Pilots and Navigators -- Effects of Slow Cortical Potentials on Reaction Time -- Effect of Sound Pressure
Direction and Frequency Spectrum of Clicks on Brain Stem Responses in Children -- Relations Between Contingent Negative Variation and Behavior Under Psychoactive Drugs in Man -- Evoked Potential Abnormality and Disability in Brain
Damaged Patients: A Replication Study and Preliminary Findings in Relation to Outcome -- Electrocortical Manifestations of Complementary Hemispheric Specialization in an Expectancy Task -- The Effects of Optical Blur and Grating
Adaptation on Amplitude and Phase of Evoked Potentials -- Operant Evoked Potential Conditioning in Animal and Man -- Visual Evoked Potentials During Stimulus Discrimination Learning -- The Utilization of Evoked Potentials in
Psychopharmacology and Pharmacopsychiatry -- Discriminate Function Models of ERP Data in Hyperactive Children -- Auditory Evoked Potentials as Probes of Lateralized Information Processing in Adults and Infants -- Auditory Evoked
Potentials Indicate Attentive Dysfunctions in Hyperkinetic Adolescents -- Diminished CNV Rebound and Perseverative Attention Set in Older Subjects -- Late Components of the Auditory Evoked Response in Schizophrenics -- HAAR Transforms
of Event Related Potentials: Toward an Optimal Re-Expression of the Data -- Developmental Changes in ERP Preceding Movement: Relation to Variability and IQ -- Evoked Potentials in the Differential Diagnosis of Sensory and Neurologic
Impairment in Children -- Contributor Index -- Author Index
ISBN:9781468434835
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:NATO Conference Series : 9
Keywords: Medicine , Pathology , Medicine & Public Health , Pathology
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Call number:SPRINGER-1978-9781461589488:ONLINE Show nearby items on shelf
Title:Pentachlorophenol Chemistry, Pharmacology, and Environmental Toxicology
Author(s):
Date:1978
Size:1 online resource (402 p.)
Note:10.1007/978-1-4615-8948-8
Contents:I. Usage Patterns and Environmental Fate of Pentachlorophenol -- Patterns of Pentachlorophenol Usage in Canada — An Overview -- Patterns of Pentachlorophenol Usage in the United States of America — An Overview -- Photolysis of
Pentachlorophenol in Water -- Degradation of Pentachlorophenol in Soil, and by Soil Microorganisms -- The Fate of Pentachlorophenol in an Aquatic Ecosystem -- The Environmental Fate of 14C-Pentachlorophenol in Laboratory Model
Ecosystems -- II. Pharmacology and Toxicology of Pentachlorophenol -- A. Metabolism -- Microbial Metabolism of Pentachlorophenol -- Fate of Pentachlorophenol in the Blue Crab, Callinectes sapidus -- Metabolism of Pentachlorophenol in
Fishes -- Studies on the Uptake, Disposition and Metabolism of Pentachlorophenol and Pentachloroanisole in Rainbow Trout (Salmo gairdneri) -- Dechlorination of Pentachlorophenol in vivoandin vitro -- Pentachlorophenol in Different
Species of Vertebrates after Administration of Hexachlorobenzene and Pentachlorobenzene -- B. Comparative Toxicology and Pharmacology -- Toxicity of Pentachlorophenol and Related Compounds to Early Life Stages of Selected Estuarine
Animals -- Effects of Sodium Pentachlorophenate on Several Estuarine Animals: Toxicity, Uptake and Depuration -- Effects of Dowicide® G-ST on Development of Experimental Estuarine Macrobenthic Communities -- Effects of
Pentachlorophenol on the Meiobenthic Nematodes in an Experimental System -- Effect of Sodium Pentachlorophenate on the Feeding Activity of the Lugworm, Arenicola cristata Stimpson -- Toxicity of Sodium Pentachlorophenate to the Grass
Shrimp, Palaemonetes pugio, in Relation to the Molt Cycle -- Inhibition of Limb Regeneration in the Grass Shrimp, Palaemonetes pugio, by Sodium Pentachlorophenate -- Effect of Sodium Pentachlorophenate on Exoskeletal Calcium in the
Grass Shrimp, Palaemonetes pugio -- Ultrastructural Changes Induced by Sodium Pentachlorophenate in the Grass Shrimp, Palaemonetes pugio, in Relation to the Molt Cycle -- Effects of Sodium Pentachlorophenate and 2,4-Dinitrophenol on
Respiration in Crustaceans -- Effects of Sodium Pentachlorophenate and 2,4-Dinitrophenol on Hepatopancreatic Enzymes in the Blue Crab, Callinectes sapidus -- Effect of Pentachlorophenol on the ATPases in Rat Tissues -- Effects of
Sodium Pentachlorophenate on Survival and Energy Metabolism of Embryonic and Larval Steelhead Trout -- Results of Two-Year Toxicity and Reproduction Studies on Pentachlorophenol in Rats -- III. Chlorophenols and Their Contaminants:
Chemistry, Toxicology, Environmental Residues and Environmental Impact -- Impurities in Commercial Products Related to Pentachlorophenol -- Genetic Activity of Chlorophenols and Chlorophenol Impurities -- Negative Chemical Ionization
Mass Spectrometry: Applications in Environmental Analytical Chemistry -- Human Exposure to Pentachlorophenol -- Survey of Pesticide Residues and Their Metabolites in Urine from the General Population -- Health Implications of
2,3,7,8-Tetrachlorodibenzo-p-dioxin Exposure in Primates -- Renal Effects of 2,3,7,8-Tetrachlorodibenzo-p-dioxin -- Environmental Impact of Pentachlorophenol and Its Products—A Round Table Discussion
ISBN:9781461589488
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:Environmental Science Research : 12
Keywords: Environment , Air pollution , Environment , Atmospheric Protection/Air Quality Control/Air Pollution
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Call number:SPRINGER-1978-9781461340188:ONLINE Show nearby items on shelf
Title:Biochemistry of Silicon and Related Problems
Author(s):
Date:1978
Size:1 online resource (591 p.)
Note:10.1007/978-1-4613-4018-8
Contents:General Chemistry of Silicon -- Aqueous Silicic Acid, Silicates and Silicate Complexes -- Hydrogen-Bonded Complexes of Silica with Organic Compounds -- The Silicon-Nitrogen Bond. A Short Survey -- Silicon in Soil, Plants and
Microorganisms -- Effect of Interactions of Silicious Components and Organic Substances on Life in Soil — A Contribution to Plant Production -- Isolation and Characterization of a Silicon-Organic Complex from Plants -- Biodegradation
of Silicon-Oxygen-Carbon- and Silicon-Carbon-Bonds by Bacteria — A Reflection on the Basic Mechanisms for the Biointegration of Silicon -- Regulation of Metabolism by Silicate in Diatoms -- Role of Silicon in Diatom Metabolism and
Silicification -- Physiological Significance of Silicon Compounds in Animals and Man -- Significance and Functions of Silicon in Warm-Blooded Animals. Review and Outlook -- Essentiality and Function of Silicon -- Silicon Levels in
Human Tissues -- Silicon, Endocrine Balance and Mineral Metabolism (Calcium and Magnesium) -- The Physiological Role of Silicon and Its Anti-Atheromatous Action -- Isolation and Characterization of a Characteristic Phosphato-Silicate
from Human Lungs with Silicosis -- Silicosis and Other Diseases Caused by Silicon Compounds -- Carcinogenic Potential of Silica Compounds -- Interactions of Silica and Asbestos with Macrophages -- Cellular Reactions with Silica --
Old-New Problems of Silicotic Fibrosis -- Biological and Pharmacological Effects of Organo-Silicon Compounds -- Biological Activity of Silatranes -- Biological Activity of Nitrogen-Containing Organosilicon Compounds -- Silica-Pharmaca
-- The Pharmacology of Silanes and Siloxanes -- Biochemical Effects of 2, 6-cis-Diphenylhexamethyl-cyclotetrasiloxane in Man -- Structural and Analytical Aspects of Organosilicon Compounds -- Structural Aspects on Organosilicon
Compounds -- Analysis of some Organosilicon Compounds in Biological Material -- Discussion and Summary -- Silicon in Biological Systems -- Final Discussion -- List of Participants
ISBN:9781461340188
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:Nobel Foundation Symposia : 40
Keywords: Life sciences , Biochemistry , Life Sciences , Biochemistry, general
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Call number:SPRINGER-1975-9781468426342:ONLINE Show nearby items on shelf
Title:Behavioral Pharmacology The Current Status
Author(s):
Date:1975
Size:1 online resource (301 p.)
Note:10.1007/978-1-4684-2634-2
Contents:The future of behavioral pharmacology -- Session I Environmental Influences Affecting the Voluntary Intake of Drugs -- Environmental influences affecting the voluntary intake of drugs: an overview -- An experimental analysis of
behavioral factors in drug dependence -- Second-order schedules of drug injection -- Behavioral functions of narcotic antagonists: response-drug contingencies -- Experimental models for the modification of human drug
self-administration: Methodological developments in the study of ethanol self-administration by alcoholics -- Session II Interactions of Behavioral and Neurochemical Processes -- On neurochemistry and behavior -- Behavioral correlates
of serotonin depletion -- Neurochemical changes associated with schedule-controlled behavior -- Serotonergic and cholinergic mechanisms during disruption of approach and avoidance behavior -- Catecholamines and drug—behavior
interactions -- Session III Behavioral Toxicology -- Behavioral toxicology: A developing discipline -- Assessing the impact of low level chemicals on development: behavioral and latent effects -- Amphetamine toxicity: behavioral and
neuropathological indexes -- Psychophysical evaluation of toxic effects on sensory systems -- Behavioral effects of mercury and methylmercury -- Session IV Contingencies of Reinforcement as Determinants of Drug Response --
Schedule-controlled behaviors as determinants of drug response -- Determinants of drug effects on punished responding -- The role of discriminative stimuli in modulating drug action -- Reinforcement schedules and extrapolations to
humans from animals in behavioral pharmacology -- Discrete trial analysis of drug action
ISBN:9781468426342
Series:eBooks
Series:SpringerLink (Online service)
Series:Springer eBooks
Series:FASEB Monographs : 4
Keywords: Medicine , Pharmacology , Behavioral sciences , Biomedicine , Pharmacology/Toxicology , Behavioral Sciences
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Call number:QC454.M3W48::1986 Show nearby items on shelf
Title:Mass spectrometry : applications in science and engineering
Author(s): Frederick Andrew White 1918-
George M.(Marshall) Wood 1933-
Date:1986
Publisher:John Wiley and Sons: New York
Size:773 pgs.
Contents:Part I: Instrumentation - 1. Introduction: Atoms, Molecules, Ions, and Isotopes, 2. Ion Sources, 3. Types of Spectrometers, 4. Tandem Systems and Special Types, 5. Detection of ion Beams, 6. Computer-Aided Data Processing, 7. Chromatography / Mass Spectrometry
Part II: Engineering and the Physical Sciences - 8. Geochemistry and Geochronology, 9. Atmospheric, Lunar, and Planetary Measurements, 10. Metals, Glasses, Ceramics, and Composites, 11. Electronic Materials and Devices, 12. Electrophysics, 13. Energy System Diagnostics: Solar, Fossil, Fission, Fusion, 14. On-Line Monitoring and Process Control
Part III: Environmental Measurements and the Life Sciences - 15. Air and Water Monitoring, 16. Agriculture and Food Science, 17. Beomedical Applications, 18. Pharmacology, 19. Toxicology and Forensic Science, 20. New Frontiers in Mass Spectrometry and Ion Beam Technology
Appendices: 1. Isotopic Abundances of the Elements, 2. Ionization Potentials, Electron Affinities, Work Functions, and Melting Points
ISBN:0471092363
Keywords: Mass spectrometry.
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