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SPIRES-BOOKS: FIND KEYWORD RNA-LIGAND INTERACTIONS *END*INIT* use /tmp/qspiwww.webspi1/3549.524 QRY 131.225.70.96 . find keyword rna-ligand interactions ( in books using www Cover
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Call number:SPRINGER-2013-9783642375552:ONLINE Show nearby items on shelf
Title:Protein-Nanoparticle Interactions [electronic resource] : The Bio-Nano Interface
Author(s): Masoud Rahman
Sophie Laurent
Nancy Tawil
L'Hocine Yahia
Morteza Mahmoudi
Date:2013
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:In recent years, the fabrication of nanomaterials and exploration of their properties have attracted the attention of various scientific disciplines such as biology, physics, chemistry, and engineering. Although nanoparticulatesystems are of signific ant interest in various scientific and technological areas, there is little known about the safety of these nanoscale objects. It has now been established that the surfaces of nanoparticles are immediatelycovered by biomolecules (e.g. proteins, ions, and enzymes) upon their entrance into a biological medium. This interaction with the biological medium modulates the surface of the nanoparticles, conferring a biological identity totheir surfaces (referred to as a corona), which determines the subsequent cel lular/tissue responses. The new interface between the nanoparticles and the biological medium/proteins, called bio-nano interface, has been veryrarely studied in detail to date, though the interest in this topic is rapidly growing. In this book, the impor tance of the physiochemical characteristics of nanoparticles for the properties of the protein corona is discussed indetail, followed by comprehensive descriptions of the methods for assessing the protein-nanoparticle interactions. The advantages and limi tations of available corona evaluation methods (e.g. spectroscopy methods, mass spectrometry,nuclear magnetic resonance, electron microscopy, X-ray crystallography, and differential centrifugal sedimentation) are examined in detail, followed by a discussi on of the possibilities for enhancing the current methods and a call fornew techniques. Moreover, the advantages and disadvantages of protein-nanoparticle interaction phenomena are explored and discussed, with a focus on the biological impacts
Note:Springer eBooks
Contents:The Biological Significance of Nano interactions
Nanoparticle and Protein Corona
Protein Corona: Applications and Challenges
Analytical Methods for Corona Evaluations
ISBN:9783642375552
Series:e-books
Series:SpringerLink (Online service)
Series:Springer Series in Biophysics, 0932-2353 : v15
Series:Physics and Astronomy (Springer-11651)
Keywords: Life sciences , Toxicology , Biochemistry , RNA-ligand interactions , Nanotechnology
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Call number:SPRINGER-2013-9783642161056:ONLINE Show nearby items on shelf
Title:Membrane Biophysics [electronic resource]
Author(s): Mohammad Ashrafuzzaman
Jack Tuszynski
Date:2013
Publisher:Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:Physics, mathematics and chemistry all play a vital role in understanding the true nature and functioning of biological membranes, key elements of living processes. Besides simple spectroscopic observations and electricalmeasurements of membranes we address in this book the phenomena of coexistence and independent existence of different membrane components using various theoretical approaches. This treatment will be helpful for readers who want tounderstand biological processes by applying both simpl e observations and fundamental scientific analysis. It provides a deep understanding of the causes and effects of processes inside membranes, and will thus eventually open new doorsfor high-level pharmaceutical approaches towards fighting membrane- and ce ll-related diseases
Note:Springer eBooks
Contents:Structure of Membranes
Lipids in Membranes
The Membrane as a Transporter
Lipid Bilayer
Membrane Protein Coupling
Membrane
Based Nanotechnology and Drug Delivery
Membrane
Related Diseases
ISBN:9783642161056
Series:e-books
Series:SpringerLink (Online service)
Series:Biological and Medical Physics, Biomedical Engineering, 1618-7210
Series:Physics and Astronomy (Springer-11651)
Keywords: Chemistry, Physical organic , RNA-ligand interactions , Cell membranes
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Call number:SPRINGER-2009-9789048123391:ONLINE Show nearby items on shelf
Title:From Molecules to Medicines [electronic resource] : Structure of Biological Macromolecules and Its Relevance in Combating New Diseases and Bioterrorism
Author(s): Joel L Sussman
Paola Spadon
Date:2009
Publisher:Dordrecht : Springer Netherlands
Size:1 online resource
Note:Springer e-book platform
Note:Springer 2013 e-book collections
Note:The synergism played by crystallography and drug discovery is the central focus of this volume which comprises papers presented at the 40th Erice Course held from 28 May to 8 June 2008. A key theme throughout the book is thedependence of modern struc tural science on multiple experimental and computational techniques, and it is the development of these techniques and their integration that will take us forward in the future
Note:Springer eBooks
Contents:Preface. List of Contributors. Surface Proteins of Gram
Positive Pathogens: Using Crystallography to Uncover Novel Features in Drug and Vaccine Candidates
The Rapid Crystallization Strategy for Structure
Based Inhibitor Design
Fragment
Based Drug Discovery in Academia: Experiences from a Tuberculosis Programme
Structural Biology Contributions to the Discovery of Drugs to Treat Chronic Myelogenous Leukemia
Integrating Crystallography Into Early Metabolism Studies
The Foundations of Protein
Ligand Interaction
Structure
Based Design of TRNA
Guanine Transglycosylase Inhibitors
ISBN:9789048123391
Series:e-books
Series:SpringerLink (Online service)
Series:NATO Science for Peace and Security Series A: Chemistry and Biology, 1874-6489
Series:Physics and Astronomy (Springer-11651)
Keywords: Computer simulation , Biochemistry , RNA-ligand interactions , Bioinformatics , Crystallography
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